Clinical trials: Cancer Surgery
Fracture at Wrist and/or Hand Level, Rupture of Tendon of Wrist and Hand
USG Brachial Plexus Block for Upper Extremity Surgery
Ultrasound-guided (USG) brachial plexus (BP) block efficacy at the Supraclavicular (SCL), Lateral- Infraclavicular (LIC) and Axillary (AX) level: Randomized, observer-blinded study of the single-penetration…
- Conditions
- Fracture at Wrist and/or Hand Level, Rupture of Tendon of Wrist and Hand, Injuries to the Wrist, Hand and Fingers (S60-S69), Ganglion Cysts
- Trial name
- NCT01993290
- Testing
- Ropivacaine
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Jens Borglum Neimann
Anxiety Disorders, Depression
Emotional Impact of the Way Conducting Cancer Patients to the Surgical Center
Cancer is an extremely aggressive disease, anxiety and depression are consequences some patients may develop from diagnosis continuing during treatment. A measures control of the cancer is surgery for removal tumor.
- Trial name
- NCT03576482
- Testing
- Transport on foot
- Where
- Brazil
- Volunteers
- 176 people
- Sponsor
- Barretos Cancer Hospital
Breast Cancer-Related Arm Lymphedema, Quality of Life Impairment
Prehabilitation of Breast Cancer-Related Lymphedema
This prospective prehabilitation study aims to evaluate the effects of an individualized exercise program initiated before breast cancer surgery and continued for 12 months postoperatively.
- Conditions
- Breast Cancer-Related Arm Lymphedema, Quality of Life Impairment, Fatigue Syndrome, Chronic, Prehabilitation
- Trial name
- NCT07301580
- Testing
- Prehabilitation Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- University of Health Sciences Balikesir Hospital Eduation and Research
Colonic Neoplasms
Laparoscopic Versus Open Surgery for Colon Cancer With Visceral Obesity
This study aims to elucidate whether there is a difference in long-term prognosis between laparoscopic surgery and open surgery in colon cancer patients with visceral obesity.
- Trial name
- LOVO (NCT07314996)
- Testing
- Laparoscopic surgery, Open surgery
- Where
- China
- Volunteers
- 664 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Clinical Stage 0 Gastric Cancer AJCC v8, Clinical Stage I Gastric Cancer AJCC v8
Early Recovery After Surgery Protocol in Improving Quality of Life in Participants With Stage 0-IIIC Gastric Cancer Undergoing Surgery
This phase II trial studies how well an early recovery after surgery protocol works in enhancing quality of life in participants with stage 0-IIIC gastric cancer undergoing surgery.
- Conditions
- Clinical Stage 0 Gastric Cancer AJCC v8, Clinical Stage I Gastric Cancer AJCC v8, Clinical Stage II Gastric Cancer AJCC v8, Clinical Stage IIA Gastric Cancer AJCC v8
- Trial name
- NCT03997162
- Testing
- Best Practice, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- City of Hope Medical Center
Surgery
Short-term Outcomes of SILS+1 Versus CLS for Distal Gastric Cancer
To evaluate the short-term outcomes of single-incision plus one-port laparoscopic surgery (SILS + 1) versus conventional laparoscopic surgery(CLS) for distal gastric cancer whose clinical stage was cT1-3N0-2M0
- Trial name
- NCT05035446
- Testing
- single-incision plus one-port laparoscopic surgery, conventional laparoscopic surgery
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Fujian Cancer Hospital
Gastric Cancer, Pain, Postoperative
Comparison of the Effect of Intravenous and Perineural Dexmedetomidine in Gastric Cancer Surgery
Using random case assignment to investigate the analgesic and sedative effect of intravenous dexmedetomidine and dexmedetomidine as a local anesthetic adjuvant in ultrasound-guided subcostal TAP block in gastric cancer patient…
- Trial name
- NCT03393403
- Testing
- Dexmedetomidine, 0.9% Sodium-chloride
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Surgical Site Infection
Surgical-Site Infection After Laparoscopic Right Colectomy
Laparoscopic right colectomy with intracorporeal anastomosis seems to be associated with several short-term benefits. It could reduce the postoperative infection rate and shorten the hospital stay.
- Trial name
- NCT04350203
- Testing
- Laparoscopic right colectomy with intracorporeal anastomosis (IA), Laparoscopic right colectomy with extracorporeal anastomosis (EA)
- Where
- Spain
- Volunteers
- 108 people
- Sponsor
- Hospital Plató
Prostate Cancer, Prostatic Cancer
CyberKnife Radiosurgery For Low & Intermediate Risk Prostate Cancer: Emulating HDR Brachytherapy Dosimetry
The purpose of this study is to investigate the effects of CyberKnife radiosurgery in patients with early stage organ-confined prostate cancer and to evaluate the effects of this treatment on the quality of life over time.
- Conditions
- Prostate Cancer, Prostatic Cancer, Prostatic Neoplasms, Prostate Neoplasms
- Trial name
- NCT00643617
- Testing
- CyberKnife Stereotactic Radiosurgery - Low Risk, CyberKnife Stereotactic Radiosurgery - Intermediate Risk
- Where
- 18 sites in United States
- Volunteers
- 307 people
- Sponsor
- Accuray Incorporated
Breast Neoplasms
Comparing Quality of Recovery Between ESPB and IV Lidocaine After Major Breast Cancer Surgery
The erector spinae plane block (ESPB) is gaining popularity as a regional anesthetic technique for major breast cancer surgery. Although there is controversy about its mechanism of action, emerging evidence suggests that clinical…
- Trial name
- NCT06490718
- Testing
- USG ESPB, Intravenous Infusion
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
Bladder Cancer, Bladder Cancer Stage I
Loop Resection or Cold-cup Biopsy? A Study Comparing the Accuracy of Muscle Samples During Bladder Tumor Surgery
In this report the investigators compared two deep muscle sampling methods (Loop resection and Cold-Cup Biopsy) during endoscopic resection of bladder tumors for patients with suspected bladder cancer in Tygerberg hospital.
- Conditions
- Bladder Cancer, Bladder Cancer Stage I, TURBT
- Trial name
- NCT06796413
- Testing
- Loop Resection or Cold-cup biopsy
- Where
- South Africa
- Volunteers
- 120 people
- Sponsor
- University of Stellenbosch
Urinary Incontinence
Whole Body Vibration and Pelvic Floor Exercises on Urinary Incontinence
Stress urinary incontinence is common in men following prostate cancer surgery. Rehabilitative interventions incorporate pelvic floor muscle training, biofeedback, electrical stimulation, lifestyle changes, or a combination of…
- Trial name
- [PTREC] (NCT03325660)
- Testing
- whole body vibration
- Volunteers
- 61 people
- Sponsor
- Ahlia University
Head and Neck Cancer, Recurrent Cancer
Postoperative Complication After Free Flap Reconstruction for Head and Neck Cancer
This study was designed to investigate the outcome of free-flap reconstruction surgery following head and neck cancer resection between primary and recurrent head and neck cancer patients.
- Conditions
- Head and Neck Cancer, Recurrent Cancer, Surgery--Complications
- Trial name
- NCT04326088
- Testing
- Reconstruction group, Recurrent group
- Where
- Taiwan
- Volunteers
- 2,004 people
- Sponsor
- Chang Gung Memorial Hospital
Breast Neoplasms
Targeting the Hippo Transducer TAZ in Breast Cancer With Statins
This pre-surgical, window-of-opportunity study is designed to investigate whether atorvastatin reduces the proliferation marker Ki-67 via modulation of the Hippo transducer TAZ.
- Trial name
- TRINACRIA (NCT02416427)
- Testing
- Atorvastatin
- Volunteers
- 78 people
- Sponsor
- Regina Elena Cancer Institute
Postoperative Pain, Inflammatory Response
Bilateral Ultrasound Guided Quadratus Lumborum Versus Lumbar Epidural Block on Postoperative Analgesia, and Inflammatory Response in Abdominal Surgery
This study aims at comparing the effects of bilateral ultrasound-guided quadratus lumborum block versus lumbar epidural block on postoperative analgesia and inflammatory response following major lower abdominal cancer surgery.
- Trial name
- NCT03958942
- Testing
- Ultrasound quadratus lumborum block with bupivacaine 25%, lumbar epideural block with bupivacaine 25%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Postoperative Pain, Postoperative Complications
PERiX: Comparison of Efficacy Between Placement of Epidural Catheters X-ray Guided and LOS Technique
The use of epidural catheters for postoperative analgesia in pancreatic surgery is recommended by the guidelines of the ERAS society.
- Conditions
- Postoperative Pain, Postoperative Complications, Pancreatic Cancer, Haemodynamic Instability
- Trial name
- PERiX (NCT03685370)
- Testing
- LOS, X-ray placement
- Where
- Italy
- Volunteers
- 154 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Glioma
Pharmacokinetics (PK) Study of AC480 for Recurrent Glioma
The primary objective is to evaluate the intratumoral and plasma pharmacokinetics of AC480 among patients who are candidates for a resection with a recurrent malignant glioma who are not on CYP-3A enzyme inducing anti-epileptic…
- Trial name
- NCT00979173
- Testing
- AC480
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Annick Desjardins
Dupuytren Contracture
Trial Comparing Treatment Strategies in Dupuytren's Contracture
Trial is a prospective, randomized, controlled, outcome assessor-blinded, three armed parallel 1:1:1, multicenter trial. The research objective is to determine, which treatment strategy 1) primary percutaneous needle fasciotomy…
- Trial name
- DETECT (NCT03192020)
- Testing
- Percutaneous needle fasciotomy (PNF), Collagenase Clostridium Histolyticum (CCH) 2.9 MG/ML [Xiaflex], Limited fasciectomy (LF)
- Where
- 6 sites in Finland
- Volunteers
- 302 people
- Sponsor
- Tampere University
Colonrectal Cancer, Colonrectal Cancer (CRC)
Compassion-Based Rehabilitation Needs Assessment Following Colorectal Cancer Surgery
This randomized controlled trial evaluated the effect of a compassion-based intervention compared with standard procedure for rehabilitation needs assessment among patients undergoing surgery for colorectal cancer with curative…
- Trial name
- NCT07876388
- Testing
- Compassionate Access Targeted Therapy
- Where
- Denmark
- Volunteers
- 77 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Head and Neck Cancer
Ph II Long Term/Low Dose Xeloda in Head and Neck Squamous Cell Carcinoma After Surgery, Radiation & or Chemo
RATIONALE: Drugs used in chemotherapy, such as capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00258310
- Testing
- capecitabine, Surgery, chemotherapy and/or radiotherapy
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
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