Clinical trials: CT Angiography
Acute Ischemic Stroke and Transient Ischemic Attacks
Cardiac CT Angiography in Acute Stroke Imaging (SCOPE-CT)
Stroke can occur when a blood clot travels to the brain and blocks blood flow. In some patients, these blood clots may originate in the heart.
- Trial name
- SCOPE-CT (NCT07896889)
- Testing
- Cardiac CT Angiography
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Ottawa Hospital Research Institute
Coronary Arterial Disease (CAD)
Combined Coronary CT Angiography and CT Perfusion in Coronary Artery Disease (CoroFusion)
Coronary computed tomography angiography (CTA) provides high-resolution imaging of coronary artery disease (CAD), revealing stenosis, plaque characteristics, and hemodynamic markers like CT-derived fractional flow reserve…
- Trial name
- NCT06949150
- Testing
- coronary angiography, Medical therapy
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shanghai Zhongshan Hospital
Acute Myocardial Infarction, Cardiovascular Diseases
Effect of infLuenza vaccInation After Myocardial INfArction on Cardiac inflammaTory responsE
The goal of this randomized, double-blind, placebo-controlled clinical trial is to investigate the immunological effects of influenza vaccination outside of the influenza season on arterial inflammation in patients with a recent…
- Conditions
- Acute Myocardial Infarction, Cardiovascular Diseases, Inflammatory Response
- Trial name
- ELIMINATE (NCT06336317)
- Testing
- Influenza vaccine
- Where
- 3 sites in Denmark, Sweden and 1 more
- Volunteers
- 90 people
- Sponsor
- Region Örebro County
Coronary Artery Disease, CT
Coronary Computed Tomography Angiography (CCTA) for the Pre-procedural Planning of Percutaneous Coronary Intervention
The CT-PLAN PCI trial will evaluate whether CCTA-guided PCI improves procedural efficiency compared with routine PCI (without pre-procedural CCTA-guidance for PCI planning) using procedural time as the primary endpoint.
- Trial name
- CT-PLAN-PCI (NCT07691502)
- Testing
- CT-guided PCI, Routine PCI
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Minneapolis Heart Institute Foundation
Coronary Artery Disease, Atheroscleroses, Coronary
Vascular Inflammation ReDuction and Perivascular Fat Imaging by Computed Tomography
The goal of this clinical trial is to compare the effect of standard of care management vs. CaRi-Heart based management on vascular inflammation in patients with increased Fat Attenuation Index-Score.
- Conditions
- Coronary Artery Disease, Atheroscleroses, Coronary, Vascular Inflammation
- Trial name
- VIRDICT (NCT06083337)
- Testing
- CaRi-Heart device
- Where
- Greece
- Volunteers
- 140 people
- Sponsor
- Hippocration General Hospital
Coronary Disease
International PRospective Multicenter Study On RadiaTion Dose Estimates Of Coronary CT AngIOgraphy IN Daily Practice
Estimation of radiation dose of coronary multislice computed tomography (MSCT) angiography in daily practice in an international, multicenter and vendor-independent trial.
- Trial name
- PROTECTION-I (NCT00610766)
- Where
- Germany
- Volunteers
- 1,965 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Coronary Artery Disease, Atherosclerosis
Measuring Athlete's Risk of Cardiovascular Events 3 (MARC-3)
Regular endurance exercise is widely known to improve cardiovascular health and reduce the risk of heart disease. Yet several imaging studies have shown that male endurance athletes have a higher prevalence of coronary artery…
- Trial name
- MARC-3 (NCT07625488)
- Where
- 2 sites in Netherlands
- Volunteers
- 250 people
- Sponsor
- Radboud University Medical Center
Coronary Atherosclerosis
Subclinical COronary Atheroscleorosis Updated With Coronary cT Angiography (SCOUT Study)
The purpose of this study is to validate the usefulness of 64-slice multi-detecter computeted tomography as a screening tool in asymptomatic population.
- Trial name
- NCT00431860
- Testing
- Coronary computed tomographic angiography
- Where
- South Korea
- Volunteers
- 3,000 people
- Sponsor
- Seoul National University Bundang Hospital
ACS (Acute Coronary Syndrome), SGLT2 Inhibitors
CCTA Evaluation of SGLT2i-related Pericoronary Fat Changes in Non-diabetic ACS Patients Without HF
The goal of this clinical trial is to learn if dapagliflozin, a sodium-glucose cotransporter 2 inhibitor (SGLT2i), can reduce coronary artery inflammation in people with acute coronary syndrome (ACS) who do not have diabetes or…
- Trial name
- DAPA-PCAT (NCT07351643)
- Testing
- Dapagliflozin
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Shenyang Northern Hospital
Atherosclerosis, Coronary Artery Disease
COroNary CT Angiography Evaluation For Clinical Outcomes: An InteRnational Multicenter Registry (CONFIRM)
The CONFIRM study was developed to examine the prognostic value of cardiac computed tomographic angiography (CCTA) findings for prediction of future adverse cardiac events related to coronary artery disease (CAD) in a large…
- Conditions
- Atherosclerosis, Coronary Artery Disease, Cardiovascular Disease
- Trial name
- CONFIRM (NCT01443637)
- Where
- 20 sites in United States, Austria and 5 more
- Volunteers
- 34,000 people
- Sponsor
- Weill Medical College of Cornell University
Coronary Artery Disease, Cardiovascular Diseases
Comparison of the Diagnostic Performance and Costs of FFRB Vs. Standard Care in Suspected Coronary Artery Disease.
Chest pain due to coronary artery disease (CAD) is a main driver of healthcare costs. Fractional flow reserve (FFR) measurement during invasive coronary angiography (ICA) is the gold standard to discriminate ischemia.
- Conditions
- Coronary Artery Disease, Cardiovascular Diseases, Cardiovascular; Stenosis, Coronary Occlusion
- Trial name
- ECONOMY (NCT06681584)
- Testing
- CTCA
- Where
- 3 sites in Singapore
- Volunteers
- 340 people
- Sponsor
- National Heart Centre Singapore
Cardiovascular Disease
Coronary CT Angiography to Predict Vascular Events In Noncardiac Surgery patIents cOhort evaluatioN (CTA -VISION) Study
Worldwide 200 million adults annually undergo major noncardiac surgery and 5 million of these patients will suffer a major vascular complication.
- Trial name
- CTA-VISION (NCT01635309)
- Testing
- Coronary CT Angiogram
- Where
- Canada
- Volunteers
- 987 people
- Sponsor
- Canadian Institutes of Health Research (CIHR)
Coronary Disease
Diagnostic Accuracy of CT-FFR Compared to Invasive Coronar Angiography With Fractional Flow Reserve
Invasive coronary angiography is currently considered gold standard in the assessment of coronary artery disease although the method has limitations.
- Trial name
- NCT03045601
- Testing
- CT-FFR, Stress echocardiography
- Where
- Norway
- Volunteers
- 182 people
- Sponsor
- St. Olavs Hospital
Magnetic Resonance Angiography
Comparison of Magnetic Resonance Coronary Angiography (MRCA) With Coronary Computed Tomography Angiography (CTA)
Magnetic resonance coronary angiography (MRCA) has its advantage in its ability to assess the coronary artery morphology without radiation or contrast media.
- Trial name
- NCT03768999
- Testing
- Non-contrast magnetic resonance coronary angiography (MRCA)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Johns Hopkins University
Coronary Artery Disease
Artificial Intelligence for Preventing Heart Disease (AiPHD): Observational, Single Center, Prospective and Retrospective Study
Coronary artery disease (CAD) is a leading cause of mortality in western countries. Coronary computed tomography angiography (cCTA) is the first-line imaging test in patients with suspected obstructive CAD.
- Trial name
- AiPHD (NCT06029387)
- Where
- Italy
- Volunteers
- 3,000 people
- Sponsor
- IRCCS San Raffaele
Coronary Computed Tomographic Angiography, Myocardial Infarction (MI)
GSI Cardiac on Revolution Apex - US
The goal of this clinical data collection study is to collect raw CT scan data using a new GSI Cardiac mode on GE HealthCare's Revolution Apex CT system.
- Conditions
- Coronary Computed Tomographic Angiography, Myocardial Infarction (MI), Cardiac Catheterization
- Trial name
- NCT06702917
- Testing
- GSI Cardiac Scan, Standard of Care CCTA, Research CCTA
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- GE Healthcare
Coronary Artery Disease
Long Term Predictors of Graft Patency After Coronary Artery Bypass Graft Surgery (Multi-slice CT Coronary Angiography Study Validated by Coronary Angiography)
To detect and evaluate the predictors of graft patency after coronary artery bypass graft surgery as assessed by multi-slice CT coronary angiography validated by coronary angiography
- Trial name
- NCT03265041
- Testing
- multi-slice CT coronary angiography and coronary angiography
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Chronic Coronary Syndrome
CTFFR and Prediction of Non-Significant CAD Lesions
In this prospective cohort study, 250 patients with suspected or known CAD and at least one intermediate coronary lesion (50-70% stenosis) who had a NiFFR value greater than 0.80 underwent coronary computed tomography angiography…
- Trial name
- NCT06979427
- Testing
- NIFFR
- Where
- Iran
- Volunteers
- 250 people
- Sponsor
- Shiraz University of Medical Sciences
Coronary Artery Disease, Hydroxymethylglutaryl-CoA Reductase Inhibitors
Assessment of Change in Atherosclerotic Plaque by Serial CCTA
Assessment of Change in AtheROSclerotic Plaque by Serial CCTA (ACROSS) is designed as a prospective observational study which aim is to demonstrate the effect of statins on coronary atherosclerosis, assessed by quantitative…
- Conditions
- Coronary Artery Disease, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Coronary Arteriosclerosis
- Trial name
- ACROSS (NCT03414840)
- Testing
- Atorvastatin
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Yonsei University
CAD, Coronary Artery Disease
AI Driven National Platform for CT cOronary Angiography for clinicaL and industriaL applicatiOns Registry
The overall aim is to build an AI driven national Platform for CT cOronary angiography for clinicaL and industriaL applicatiOns (APOLLO) for automated anonymization, reporting, Agatston scoring and plaque quantification in CAD.
- Conditions
- CAD, Coronary Artery Disease, Coronary Stenosis, Plaques; Epicardial
- Trial name
- APOLLO (NCT05509010)
- Testing
- CTCA
- Where
- 3 sites in Singapore
- Volunteers
- 8,000 people
- Sponsor
- National Heart Centre Singapore