Clinical trials: COVID-19 Respiratory Infection
Covid19
Serological Profile of Children and Young Adolescents With at Least One COVID-19 Diagnosed Family Member
Use of rapid serological tests to assess the vulnerability to SARS-CoV-2 infection of subjects aged 4-16 years old and cohabiting with at least one family member who tested positive to SARS-CoV-2
- Trial name
- NCT04649944
- Testing
- Serological test and phone interview
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Milan
AI (Artificial Intelligence), Mammary Cancer
Experiment on the Use of Innovative Computer Vision Technologies for Analysis of Medical Images in the Moscow Healthcare System
It is planned to integrate various services based on computer vision technologies for analysis of the certain type of x-ray study into Moscow Unified Radiological Information Service (hereinafter referred to as URIS).
- Conditions
- AI (Artificial Intelligence), Mammary Cancer, Lung Cancer, X-Rays; Lesion
- Trial name
- NCT04489992
- Where
- Russia
- Volunteers
- 133,000 people, healthy volunteers welcome
- Sponsor
- Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department
SARS-CoV-2 Infection
Study to Evaluate the Efficacy of COVID19-0001-USR in Patients With Mild/or Moderate COVID-19 Infection in Outpatient
Determine the efficacy and safety of COVID19-0001-USR in the treatment of SARS-COV-2 infection in mild to moderate manifestations administered via nebulization/inhalation.
- Trial name
- COVID-19 (NCT04595136)
- Testing
- Drug COVID19-0001-USR, normal saline
- Where
- Colombia
- Volunteers
- 60 people
- Sponsor
- United Medical Specialties
Covid19, SARS-CoV Infection
Prevalence and Outcome of SARS-CoV-2 Infection & COVID-19 in Transplant Recipients: The COVITRA Study
This project will provide novel data using a large cohort of more than 3000 transplanted patients. Risk and protective factors for SARS-CoV-2 infection and COVID-19 disease severity will be identified.
- Conditions
- Covid19, SARS-CoV Infection, Transplantation Infection
- Trial name
- COVITRA (NCT04579471)
- Testing
- SARS-CoV-2 IgG
- Where
- Belgium
- Volunteers
- 2,000 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Ivermectin, Hydroxychloroquine
A Comparative Study on Ivermectin and Hydroxychloroquine on the COVID19 Patients in Bangladesh
COVID19 is a worldwide pandemic. Hence SARS-CoV-2 is a novel virus; there is no specific medication against it. Like other countries of the world, Bangladesh is also struggling in the case of treatment of this disease.
- Conditions
- Ivermectin, Hydroxychloroquine, COVID19
- Trial name
- NCT04434144
- Testing
- Ivermectin + Doxycycline, Hydroxychloroquine + Azithromycin
- Where
- Bangladesh
- Volunteers
- 116 people
- Sponsor
- Upazila Health & Family Planning Officer's (UHFPO) Office, Chakoria, Cox's Bazar
Coronavirus Infection, Disease Prevention
Assessment of N-95 Facemask for Use in COVID-19 Pandemic in Case of Shortage of Personal Protective Equipment
The purpose of this study is to assess the safety and efficiency of an assembled modified mask in protecting health care workers against Coronavirus in case of any personal protective equipment shortage.
- Trial name
- NCT04416919
- Testing
- Assembled mask
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Covid19
Xylocaine to Freeze During Unpleasant Nasopharyngeal Swabs
Since the beginning of the COVID-19 pandemic, nasopharyngeal swabs (NPS) have been recommended to detect the virus. This procedure has been reported to be painful by 85% of children The aim of the study was to assess whether…
- Trial name
- Xylofuns (NCT04901065)
- Testing
- Xylocaine
- Where
- Canada
- Volunteers
- 88 people
- Sponsor
- Evelyne D.Trottier
COVID19, Ophthalmopathy
Ocular Sequelae of Patients Hospitalized for Respiratory Failure During the COVID-19 Epidemic
Ophthalmologic damages secondary to COVID-19 coronavirus infection are little described. The ocular involvement is probably multiple, ranging from pathologies of the anterior segment such as conjunctivitis and anterior uveitis to…
- Trial name
- SOCOVID (NCT04387292)
- Testing
- Ophthalmologic exam
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Covid19, Contact Case
Relationship Between Biological Profiles and Clinical Evolutions Within the Same Cluster COVID-19 (COVIDCOLLECT)
The hypothesis is that from a cluster defined by a confirmed positive case of COVID-19 and its contact cases, it is possible to study the different expressions and clinical evolutions of COVID-19 infection and to explore the…
- Trial name
- COVIDCOLLECT (NCT04597736)
- Testing
- Biological collection with nasopharyngeal samples, saliva, blood, stool and urine
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Covid19, Bronchoscopy
Narrow Band Imaging Bronchoscopy During SARS-CoV2 Infection
Vascular modifications have been described during SARS-CoV2 infection, especially a dilatation of the bronchial arteries. Within the airway wall, small branches of the bronchial arteries cross the muscle layer to develop a…
- Conditions
- Covid19, Bronchoscopy, Narrow-band Imaging
- Trial name
- SARS-CoV2-NBI (NCT04884061)
- Testing
- NBI images and/or videos
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
COVID-19
Evaluation of Therapeutic Effects of Melatonin by Inhibition of NLRP3 Inflammasome in COVID19 Patients
The leading cause of death in patients with COVID19 is a severe inflammatory response caused by a cytokine storm that results in acute respiratory distress syndrome and acute pulmonary insufficiency, as well as dysfunction of…
- Trial name
- NCT04409522
- Testing
- Melatonin, The usual treatment
- Where
- Iran
- Volunteers
- 55 people
- Sponsor
- Mohammad Sadegh Bagheri Baghdasht
COVID-19, Nintedanib
Efficacy and Safety of Nintedanib in the Treatment of Pulmonary Fibrosis in Patients With Moderate to Severe COVID -19
This center intends to conduct a single-center, randomized, placebo-controlled study to evaluate the effectiveness and safety of Nintedanib ethanesulfonate soft capsule in the treatment of pulmonary fibrosis in patients with…
- Conditions
- COVID-19, Nintedanib, Safety, Effect of Drugs
- Trial name
- NCT04338802
- Testing
- Nintedanib 150 MG
- Volunteers
- 96 people
- Sponsor
- Huilan Zhang
Coronavirus Disease 2019 (COVID19)
Screening for Patients Admitted to Ain-Shams University Hospitals for SARS-COV-2 (COVID19)
The objective of this study is to screen the patients seeking hospitalization in Ain Shams university hospitals and identify a cost effective tool for continuing screening the patients all through the epidemic period
- Trial name
- NCT04443712
- Where
- Egypt
- Volunteers
- 1,900 people
- Sponsor
- Samia Girgis
Covid19
OD-doxy-PNV-COVID-19 Old Drug " DOXY " for Prevention of New Virus " COVID-19 "
Given the urgency of having guidelines for the management of COVID-19 in the current epidemic context and the lack of specific pharmacological treatment, Military Health recommends the launch of a multicenter, randomized…
- Trial name
- NCT04584567
- Testing
- Doxycyclin
- Where
- Tunisia
- Volunteers
- 194 people
- Sponsor
- Hedi Gharsallah
COVID-19
The Evaluation of Hemostasis in Hospitalized COVID-19 Patients
Coronavirus disease 2019 (COVID-19), a viral respiratory illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been shown to predispose patients to thrombotic diseases (venous and arterial) with…
- Trial name
- TARGET-COVID (NCT04493307)
- Testing
- Phlebotomy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- LifeBridge Health
COVID-19, SARS-CoV-2
Azithromycin for COVID-19 Treatment in Outpatients Nationwide
This individually randomized telemedicine-based trial aims to evaluate the efficacy of a single dose of azithromycin for prevention of progression of COVID-19 in patients with a recent positive SARS-CoV-2 test who are not…
- Trial name
- ACTION (NCT04332107)
- Testing
- Azithromycin
- Where
- United States
- Volunteers
- 263 people
- Sponsor
- Thomas M. Lietman
Colorectal Neoplasms Malignant
Effects of COVID-19 Pandemic on the Outcomes of Colorectal Cancer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been identified as the cause of the Coronavirus disease 19 (COVID-19), which was initially reported in December 2019 in China and has since rapidly spread…
- Trial name
- COVID-CRC (NCT04712292)
- Testing
- Surgical procedure for confirmed or suspected colorectal cancer
- Where
- 45 sites in Italy
- Volunteers
- 15,000 people
- Sponsor
- University of Bologna
Covid19
Luxembourg Cohort of Positive Patients for COVID-19: a Stratification Study to Predict Patient Prognosis
Predi-COVID is a prospective cohort study composed of people positively tested for COVID-19 in Luxembourg, followed digitally for monitoring participants' health evolution and symptoms at home.
- Trial name
- Predi-COVID (NCT04380987)
- Testing
- Biological sampling
- Where
- Luxembourg
- Volunteers
- 1,366 people
- Sponsor
- Luxembourg Institute of Health
Moderate COVID-19-infection
Viable Human SARS-CoV-2 Specific T Cell Transfer in Patients at Risk for Severe COVID-19
Monocentric open phase I (dose escalation component), followed by a multi-center, randomized, phase II component benchmarking IMP+SoC against SoC
- Trial name
- ACT-COVID-19 (NCT04762186)
- Testing
- human SARS-CoV 2 specific T lymphocytes
- Where
- Germany
- Volunteers
- 1 people
- Sponsor
- Universitätsklinikum Köln
Covid-19, SARS
Tocilizumab vs CRRT in Management of Cytokine Release Syndrome (CRS) in COVID-19
Some patients infected with the COVID-19 can develop uncontrolled immune response, leading to potentially life-threatening damage to lung tissue. Tocilizumab was first approved by the U.S.
- Conditions
- Covid-19, SARS, Cytokine Storm, Cytokine Release Syndrome
- Trial name
- TACOS (NCT04306705)
- Testing
- Tocilizumab, Standard of care, Continuous renal replacement therapy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Tongji Hospital
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