Clinical trials: Burn Injury
Scar
Fractional Photothermolysis for the Treatment of Burn Scars
The aim of our study is to determine the effect of fractional photothermolysis laser in the treatment of burn scars.
- Trial name
- NCT01005992
- Testing
- Fractional laser treatment, Standard scar management
- Where
- Chile
- Volunteers
- 10 people
- Sponsor
- Clinica las Condes, Chile
Burn Out, Nurses
Mitigating Burnout in Nursing and Associated Healthcare Staff
Workplace stress for healthcare workers is at an all-time high and the COVID-19 Pandemic magnified and amplified the impact of stress and burnout on health care workers, especially for frontline staff such as nurses.
- Trial name
- NCT07018609
- Testing
- Zen Den Experience, Music Therapy Experience
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Burns
Exercise Training Post Burn Injury
The purpose of this study is to determine whether a high intensity aerobic and resisted exercise program will improve physical, functional and psychological outcomes in patients post burn injury.
- Trial name
- NCT01368367
- Testing
- Intensive exercise
- Where
- Australia
- Volunteers
- 36 people
- Sponsor
- The University of Queensland
Burns
To Study the Healing Effect of Silver Impregnated Activated Carbon Fiber Wound Dressing on Deep Dermal Burn
Background: Bio-medical Carbon Technology (BCT) Antimicrobial Dressing, a novel advanced wound dressing invented by Bio-medical Carbon Technology Co., Ltd., Taiwan, consists principally of activated carbon fiber impregnated with…
- Trial name
- NCT01598493
- Testing
- BCT Antimicrobial Dressing, Flamazine
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Bio-medical Carbon Technology Co., Ltd.
Burn
VRH Pain Reduction During Burn Wound Care and Physical Therapy
Using Virtual Reality Hypnosis to relief pain and anxiety for burn patients.
- Trial name
- VRH (NCT00260221)
- Testing
- using VR hypnosis/distraction and audio hypnosis
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- National Institute of General Medical Sciences (NIGMS)
Burn, Hypertrophic Scar
Intron A for the Treatment of Hypertrophic Scar
This study assesses the intervention with antifibrotic agents, specifically interferon (IFN) to reduce the magnitude and duration of hypertrophic scar.
- Trial name
- NCT00686478
- Testing
- interferon alpha 2b
- Where
- Canada
- Sponsor
- University of Alberta
Acute Pain, Pediatric ALL
VR-PAT and fNIRS to Identify CNS Biomarkers of Pain
This study aims to use functional near-infrared spectroscopy (fNIRS) to identify and quantify pain biomarkers during burn dressing changes and pain relief induced by virtual reality (VR).
- Conditions
- Acute Pain, Pediatric ALL, Procedural Pain, Burns
- Trial name
- NCT06303687
- Testing
- VR-PAT
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Nationwide Children's Hospital
Burn Injury
A Trial of Restrictive Versus Traditional Blood Transfusion Practices in Burn Patients
The purpose of this study is to find out if burn injured patients do better receiving fewer blood transfusions than what is traditionally given.
- Trial name
- NCT01079247
- Testing
- Restrictive transfusion threshold, Liberal transfusion threshold
- Where
- 18 sites in United States, Canada and 1 more
- Volunteers
- 347 people
- Sponsor
- American Burn Association
Burns, Acute Pain
VR for Burn Dressing Changes at Home
This study will evaluate the impact of our smartphone-based Virtual Reality Pain Alleviation Tool (VR-PAT) during the repeated at-home burn dressing changes of children (5-17 years) with a burn injury in comparison with a control…
- Conditions
- Burns, Acute Pain, Procedural Pain
- Trial name
- NCT04548635
- Testing
- VR-PAT
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Nationwide Children's Hospital
Graft vs Host Disease, Congenital Aniridia
Safety and Performance Study of the ARGOS-IO System in Patients Undergoing Boston Keratoprosthesis Implantation
The ARGOS-IO pressure sensor is intended to be implanted in the human eye in combination with Boston Keratoprosthesis (BKPro) surgery and to remain in place indefinitely.
- Conditions
- Graft vs Host Disease, Congenital Aniridia, Chemical Burns, Stevens-Johnson Syndrome
- Trial name
- NCT02945176
- Testing
- ARGOS-IO system
- Where
- 2 sites in Germany
- Volunteers
- 13 people
- Sponsor
- Implandata Ophthalmic Products GmbH
Limbal Stem Cell Deficiency, Stevens-johnson Syndrome
Clinical Trial on the Effect of Autologous Oral Mucosal Epithelial Sheet Transplantation
To investigate the effect of ocular surface reconstruction and assess the safety in cultivated oral mucosal epithelial cell sheet transplantation (COMET) regarding patients with cicatricial change of ocular surface.
- Conditions
- Limbal Stem Cell Deficiency, Stevens-johnson Syndrome, Ocular Cicatricial Pemphigoid, Chemical Burn
- Trial name
- NCT02149732
- Testing
- cultivated oral mucosal epithelial sheet transplantation
- Where
- 2 sites in South Korea
- Sponsor
- Seoul National University Hospital
Partial-Thickness Burn, Thermal Burn
Silver Sulfadiazine With Hyaluronic Acid Versus Silver Sulfadiazine Alone in Partial-Thickness Burns
Partial-thickness burns are commonly treated with topical silver sulfadiazine; however, its use may delay epithelialization due to cytotoxic effects on regenerating cells.
- Trial name
- NCT07367087
- Testing
- Silver Sulfadiazine With Hyaluronic Acid, Silver Sulfadiazine
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Dr Muhammad Naveed Shahzad
Hand Burns, Flexion Contracture
Comparison of Outcome of Post Burn Flexion Contracture Release Under Tourniquet Verses Tumescent Technique in Children
Post burn flexion contractures are common in pediatric age group. Release of contracture and coverage with full thickness skin graft (FTSG) is a widely used procedure for this problem.
- Trial name
- NCT02501720
- Testing
- post burn flexion contractures release under tourniquet control, post burn flexion contractures release using tumescent solution, Contracture release and application of FTSG
- Volunteers
- 80 people
- Sponsor
- King Edward Medical University
Burns, Stroke
The Use of Simulated Patients During Basic-first Aid Courses for Laypeople
Background: Teaching first aid to laypeople is a cost-effective way to improve public health. However, it is currently unclear what the most effective ways are to teach first aid.
- Trial name
- NCT03608982
- Testing
- Simulated patient, No simulated patient
- Where
- Belgium
- Volunteers
- 1,168 people, healthy volunteers welcome
- Sponsor
- Centre for Evidence-Based Practice, Belgium
Burns
Evaluation of Antimicrobial Soft Silicone, Silver Containing, Foam Dressing, Mepilex Border Ag, in Second Degree Burns
The investigation is designed as an open, non-controlled, post-marketing investigation. Subjects with at least one second degree burn less than 9.5x15 cm in size at 1-3 sites will be included.
- Trial name
- NCT01418482
- Testing
- Mepilex Border Ag
- Where
- 2 sites in Sweden
- Volunteers
- 15 people
- Sponsor
- Molnlycke Health Care AB
Burns
Protocol of Management of Major Pediatric Burn in Intensive Care Unit
Decrease mortality and morbidity in major pediatric burns
- Trial name
- NCT04192942
- Testing
- protocol of management of major burn in intensive care unit
- Volunteers
- 100 people
- Sponsor
- Assiut University
Capsaicin, Ultaviolet B Light Burn
A Mechanistic Evaluation of the Nociceptive Desensitizing Properties of Topical Capsaicin
The aim of this project is to study the role of transient receptor potential (TRP-) channel V1 (TRPV1+) fibers in the development of cutaneous inflammation induced by epidermal Ultraviolet-B damage.
- Conditions
- Capsaicin, Ultaviolet B Light Burn, Neuropathic Pain, Lidocaine
- Trial name
- NCT03587220
- Testing
- Capsaicin Topical, Ultraviolet-B (UVB) irradiation, Histamine 1%
- Where
- Denmark
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Pain
Lidocaine For Treatment of Post-operative Pain From Donor Sites Following Burn Injury.
Burn pain is known to be one the most severe forms of acute pain often requiring large amounts of narcotics in addition to other adjuvants.
- Trial name
- LidocaineBurn (NCT02229578)
- Testing
- Lidocaine
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Florida
Hypertrophic Scar
Effect of Silicone Gel Versus Contractubex Phonophoresis for Post-burn Hypertrophic Scars
Hypertrophic scars and keloids are physically and mentally disturbed, and in addition, can cause pain and itching. Various treatment is utilized to diminish or counteract scarring.
- Trial name
- NCT03777891
- Testing
- phonophoresis with different material
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Sunburn
Clinical Trial of the Safety and Efficacy of SP160412 in the Temporary Relief of Mild to Moderate Sunburn
A phase II multicenter, double-blinded clinical trial of the safety and efficacy of SP160412 in the temporary relief of mild to moderate, (i.e. first degree) sunburn
- Trial name
- NCT03332524
- Testing
- SP160412 Ibuprofen 400 mg and Chlorpheniramine maleate 4 mg
- Where
- Mauritius
- Volunteers
- 80 people
- Sponsor
- Sephoris Pharmaceuticals LLC
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