Clinical trials: Burn
Burn Out, Nurses
Mitigating Burnout in Nursing and Associated Healthcare Staff
Workplace stress for healthcare workers is at an all-time high and the COVID-19 Pandemic magnified and amplified the impact of stress and burnout on health care workers, especially for frontline staff such as nurses.
- Trial name
- NCT07018609
- Testing
- Zen Den Experience, Music Therapy Experience
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Burns, Stroke
The Use of Simulated Patients During Basic-first Aid Courses for Laypeople
Background: Teaching first aid to laypeople is a cost-effective way to improve public health. However, it is currently unclear what the most effective ways are to teach first aid.
- Trial name
- NCT03608982
- Testing
- Simulated patient, No simulated patient
- Where
- Belgium
- Volunteers
- 1,168 people, healthy volunteers welcome
- Sponsor
- Centre for Evidence-Based Practice, Belgium
Capsaicin, Ultaviolet B Light Burn
A Mechanistic Evaluation of the Nociceptive Desensitizing Properties of Topical Capsaicin
The aim of this project is to study the role of transient receptor potential (TRP-) channel V1 (TRPV1+) fibers in the development of cutaneous inflammation induced by epidermal Ultraviolet-B damage.
- Conditions
- Capsaicin, Ultaviolet B Light Burn, Neuropathic Pain, Lidocaine
- Trial name
- NCT03587220
- Testing
- Capsaicin Topical, Ultraviolet-B (UVB) irradiation, Histamine 1%
- Where
- Denmark
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Pain
Lidocaine For Treatment of Post-operative Pain From Donor Sites Following Burn Injury.
Burn pain is known to be one the most severe forms of acute pain often requiring large amounts of narcotics in addition to other adjuvants.
- Trial name
- LidocaineBurn (NCT02229578)
- Testing
- Lidocaine
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Florida
Burn Injury
Module on Preventing Fire, Burns and Scalds Injury Among Children
The main aim of this intervention study is to test the hypothesis if school based educational intervention program will significantly improve the knowledge of primary school student on childhood burn prevention in Kuala Lumpur.
- Trial name
- NCT03618940
- Testing
- Knowledge and Attitude on burn prevention
- Where
- Malaysia
- Volunteers
- 2,335 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Skin Condition, Cleft Lip and Palate
Online Psychosocial Support for Young People With a Visible Difference: A Randomised Control Study
A visible difference can have a profound impact in a society with a massive emphasis on appearance and "looks". A vulnerable group is adolescents with a condition affecting their appearance as a result of injuries (burns…
- Conditions
- Skin Condition, Cleft Lip and Palate, Burns, Other Conditions Leading to a Visible Difference
- Trial name
- UNGFaceIT (NCT03165331)
- Testing
- Ung Face IT
- Where
- Norway
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Cryotherapy Effect, Burn Scar
Observation of the Comfort and Efficacy of CO2 Laser Combined With Cryo 6 for Burn or Linear Scars.
To investigate the effect of 10,600 nm CO2 laser combined with Zimmer Cryo 6 forced cold air device on the comfort and efficacy of patients with burn scars or post-operative linear scars, and to provide a safer, more effective…
- Conditions
- Cryotherapy Effect, Burn Scar, Scar; Previous Cesarean Section
- Trial name
- NCT05555602
- Testing
- Cold-air cooling
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kaiyang Lv, MD-PhD
Wounds and Injuries
Acute Partial Thickness Burn Study Comparing Transforming Powder Dressing to Standard of Care Dressing
This study is being performed to assess the effectiveness of Altrazeal(R) Transforming Powder Dressing (TPD) in patients with partial thickness burns compared to the current standard of care (SOC) dressing.
- Trial name
- NCT05424354
- Testing
- Altrazeal (R) Transforming Powder Dressing, Standard of Care burn dressing
- Where
- 6 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ULURU Inc.
Healthy Subjects
Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia During a Burn Injury
In several rodent studies, it has been demonstrated that very high doses of opioid antagonists (i.e., naloxone 3-10 mg/kg) administered after weeks after recovery from an inflammatory injury may lead to a reinstatement of…
- Trial name
- TCI-NX-BI (NCT02684669)
- Testing
- Naloxone, Normal saline
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- mads u werner
Hyperalgesia
The Effect of Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers
Treatment of chronic pain is a major clinical challenge since chronic pain is frequent and leads to deterioration of quality of life.
- Trial name
- RemiSun 1 (NCT00811837)
- Testing
- Midazolam, Remifentanil
- Where
- Austria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Hypertrophic Scar
Use of Autologous Platelet-Rich Plasma to Treat Hypertrophic Burn Scars
Hypertrophic burn scars are experienced by more than 70% of burn victims. They are a major source of decreased quality of life in burn patients due to pain, decreased range of motion, and poor cosmetic appearance.
- Trial name
- NCT03935594
- Testing
- PRP Injection, Saline Injection
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Stress
Associations of Communication Skills Workshop and Improvements in Stress, Burnout and Empathy and Psychometric Properties of Chinese Version of Perceived Stress Scale, Professional Fulfillment and Burnout Scale and Empathy Among Health Care Professionals
This study aims to explore associations of burn out, stress, communication skills, interpersonal effectiveness and empathy level using data collected in pre and post assessments from "Workshop of Enhancing Interpersonal…
- Trial name
- NCT04964102
- Testing
- Workshop of Enhancing Interpersonal Effectiveness, Emotional Regulation and Clinical Communication Skills
- Where
- Taiwan
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Inflammation, Sleep Deprivation
Circadian Rhythm Disruption Effects on Smoke Inhalation
Particulate matter exposure during smoke inhalation provokes inflammatory immune responses in people exposed to burning biomass including fire fighters and civilians.
- Conditions
- Inflammation, Sleep Deprivation, Circadian Rhythm Sleep Disorder, Shift Work Type, Smoke Inhalation
- Trial name
- NCT04955431
- Testing
- Sleep Restriction, Normal Sleep
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Montana
Microvesicle Particles, Thermal Burn
Pilot Studies Testing the Use of Oral Amitriptyline in Reducing Localized Burn Injury-induced Microvesicle Particle Release
The purpose of this study is to determine the amount of substances contained in skin known as microvesicle particles (MVP). The hypothesis to be tested in this study is that treatment with a single dose of 75mg of amitriptyline…
- Trial name
- NCT07640061
- Testing
- Amitriptyline
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wright State University
Fat Burn
Non-invasive Lipolysis and Improvement of Muscle Tone in Lateral Abdomen
This study will evaluate the clinical efficacy and performance of the BTL-899 device for changes in subcutaneous fat and muscle tissue in the lateral abdomen region (also referred to as flanks or "love handles").
- Trial name
- NCT05540080
- Testing
- BTL-899
- Where
- 6 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Scald Burn, Itching
Comparison of the Effects of Liquid Vaseline and Olive Oil on Itching and Scarring in Scald Burns
Pain, itching, hypertrophic scar formation after wound healing in burn patients complications, sleep disturbances in patients, anxiety, depression, and daily life It may disrupt activities and deterioration in quality of life.
- Conditions
- Scald Burn, Itching, Hypertrophic Scarring
- Trial name
- NCT06104540
- Testing
- Experimental I liquid vaseline groups, Experimental II extra virgin olive oil groups, Control Croup
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Burn Injury, Body Temperature Regulation
The Effect of Simulated Burn Injury on Post Exercise Recovery in Hot Environments
Burn survivors have difficulty thermoregulating due to reduced skin blood flow and sweating responses at the grafted sites. It has been previously shown that this impaired heat dissipation results in burn survivors experiencing…
- Conditions
- Burn Injury, Body Temperature Regulation, Cardiovascular Physiology
- Trial name
- HSR (NCT07050264)
- Testing
- Simulated burn injury via application of absorbent and impermeable material over 60% of the body
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Sunburn
Hats on Head Start: A A Survey of Sun Protection Behaviors in Head Start and Other Early Childhood Education Programs
The proposed study will assess the current sun safety policies and practices in programs for young children and to determine the willingness of stakeholders to incorporate more protective measures.
- Trial name
- NCT03199573
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Psychological Stress
Mantra Meditation to Reduce Emotional Exhaustion in Emergency Department Staff
Work in a healthcare setting, such as in an emergency department (ED), while rewarding, can be harmful to psychological well being, as demonstrated by the high numbers of Irish hospital doctors experiencing burnout.
- Trial name
- NCT02887300
- Testing
- Mantra Meditation
- Where
- Ireland
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- St. James's Hospital, Ireland
Burn Injury
Skin Wetting in Burn Survivors
This project will identify the efficacy of whole body skin wetting aimed to attenuate excessive elevations in internal body temperatures during physical activity in well-healed burn survivors.
- Trial name
- NCT06529757
- Testing
- Whole body cooling, Non-cooling
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center