Clinical trials: Burn
Burn Injury
Skin Wetting in Burn Survivors
This project will identify the efficacy of whole body skin wetting aimed to attenuate excessive elevations in internal body temperatures during physical activity in well-healed burn survivors.
- Trial name
- NCT06529757
- Testing
- Whole body cooling, Non-cooling
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Post Burn Cubital Tunnel Syndrome
Post Burn Cubital Tunnel Syndrome Electrophysioligical and Functional Responses to High Intensity Laser Therapy Versus Extracorperal Shock Wave Therapy.
Post-burn cubital tunnel syndrome is a disabling complication that may occur after upper-limb burns involving the elbow due to edema, scar formation, and tissue compression around the ulnar nerve.
- Trial name
- NCT07102992
- Testing
- High intensity laser therapy, Shock Wave therapy, Ulnar nerve gliding exercises.
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ahram Canadian University
Burns
Efferon LPS Hemoadsorption in in Patients With Thermal Burns
The aim of the study is to evaluate the safety and efficacy of multimodal (cytokine and lipopolysaccharide) hemoadsorption using the Efferon® LPS device to reduce the severity of clinical symptoms and to prevent the progression…
- Trial name
- NCT07568132
- Testing
- Efferon LPS
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Efferon JSC
Joint Contracture, Contracture
Recurrence of Extremity Joint Contracture After Z-Plasty Versus Full-Thickness Skin Graft
The purpose of this study is to compare how often joint contractures in the arms and legs come back after two common types of reconstructive surgery: Z-plasty and full-thickness skin graft (FTSG).
- Conditions
- Joint Contracture, Contracture, Cicatrix, Burn Scar Contractures
- Trial name
- NCT07885046
- Testing
- Z-Plasty, Full-Thickness Skin Graft
- Volunteers
- 300 people
- Sponsor
- Universitas Sebelas Maret
Septic Shock, Acute Respiratory Distress Syndrome
CytOSorb TreatMent Of Critically Ill PatientS Registry
Registry intended to provide a data repository and reporting infrastructure for the surveillance of CytoSorb device use in real-world critical care settings, and to serve as an objective, comprehensive, and scientifically-based…
- Conditions
- Septic Shock, Acute Respiratory Distress Syndrome, Trauma, Rhabdomyolysis
- Trial name
- COSMOS (NCT05146336)
- Testing
- CytoSorb
- Where
- 28 sites in Austria, Germany and 4 more
- Volunteers
- 3,000 people
- Sponsor
- CytoSorbents, Inc
Impact of ROM Exercises on Pain and Functional Ability in Patients With Second -Degree Burns
Impact of Range of Motion Exercises on Pain and Functional Ability
The goal of this quasi-experimental study is to evaluate the effect of range of motion (ROM) exercises on pain and functional ability among adult patients of both genders with second-degree burn injuries affecting the upper…
- Trial name
- ROM-SDB (NCT07883863)
- Testing
- Range of Motion exercises
- Volunteers
- 80 people
- Sponsor
- Al-Azhar University
Burns
Lipopolysaccharide Adsorption (Efferon LPS NEO) in Children With Thermal Burns
This observational pilot study aims to identify criteria for evaluating the effectiveness of hemoadsorption with the Efferon LPS NEO device in pediatric burn injury.
- Trial name
- NCT07248930
- Testing
- Efferon LPS NEO
- Where
- 2 sites in Russia
- Sponsor
- Efferon JSC
Burns
Lipopolysaccharide Adsorption (Efferon LPS) in Patients With Thermal Burns
This observational pilot study aims to establish criteria for evaluating the effectiveness of hemoadsorption with the Efferon LPS device in adult patients with burn injury.
- Trial name
- NCT07259668
- Testing
- Efferon LPS
- Where
- Russia
- Sponsor
- Efferon JSC
Glucose Metabolism Disorders, Hunger
Food Orders on Blood Glucose and Fuel Use at Rest
Consuming a carbohydrate-rich food as the final food in a meal, as compared to the first food in a meal, has been shown to reduce blood glucose levels after eating in both diabetes patients and in healthy controls.
- Conditions
- Glucose Metabolism Disorders, Hunger, Fat Burn
- Trial name
- NCT06763562
- Testing
- Carbohydrate-first meal, Carbohydrate-last meal
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Old Dominion University
Sepsis - to Reduce Mortality in the Intensive Care Unit, Burns Involving 20% or More of Body Surface
Evaluating the Accuracy of Multiple Blood Tests to Diagnose Sepsis in Adult Burn Patients
This prospective diagnostic accuracy study evaluates the performance of presepsin and C-reactive protein (CRP) as early biomarkers for suspected sepsis in adult burn patients.
- Trial name
- BioBurnSepsis (NCT07126574)
- Where
- South Korea
- Volunteers
- 165 people
- Sponsor
- Dohern Kym
Critical Illness, Wounds and Injury
Strategy to Avoid Excessive Oxygen Using an Autonomous Oxygen Titration Intervention
This study is a multicenter randomized controlled trial to determine the effectiveness of a closed loop/autonomous oxygen titration system (O2matic PRO100) to maintain normoxemia (goal range SpO2 90-96%, target 93%) during the…
- Conditions
- Critical Illness, Wounds and Injury, Disease Attributes, Pathologic Processes
- Trial name
- SAVE-O2 AI (NCT06374225)
- Testing
- Automated Titration (O2matic)
- Where
- 4 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Colorado, Denver
Burn
Impact of Inspiratory Muscle Training Post-Burn
Pulmonary dysfunction can be developed as a result of complications caused by direct thermal injury to the respiratory tract, smoke irritations, and respiratory tract infection.
- Trial name
- NCT07867639
- Testing
- Inspiratory muscle training, Conventional physical therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Burn
Comparison of Topical Antibiotics Versus Systemic Antibiotics in Preventing Burn Wound Infection in Pediatric Burn Patients
Burn wound infection is a common complication in children with burns and can delay healing and increase the risk of complications.
- Trial name
- NCT07870239
- Testing
- Silver Sulfadiazine Cream 1%, Amoxicillin and clavulanate
- Where
- Pakistan
- Volunteers
- 222 people
- Sponsor
- abdul mateen
Burn, Burn Injury
Assessment Of Burn Severity and Extent Spatial Frequency Domain Imaging
The goal of this pilot clinical study is to evaluate the feasibility of collecting Spatial Frequency Domain Imaging (SFDI) data in patients with circulatory compromise due to thermal burns using the FDA-cleared Clarifi Imaging…
- Trial name
- NCT06921421
- Testing
- Spatial Frequency Domain Imaging
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The Metis Foundation
Pediatric Burns
Magnesium Sulfate in Pediatric Burn Dressing Changes
Prospective feasibility trial utilizing adjuvant magnesium sulfate for analgesia/sedation during pediatric sedated burn dressing changes, which is ultimately hypothesized to decrease ketamine and/or sedative requirements.
- Trial name
- NCT07126795
- Testing
- magnesium sulfate, Normal Saline (0.9% NaCl)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Hennepin Healthcare Research Institute
Sepsis, Burn
Sepsis Biomarker Monitoring in Burn Patients
The goal of this clinical trial is to learn if using pancreatic stone protein (PSP) test results helps doctors find and treat sepsis earlier in adults with serious burn injuries.
- Conditions
- Sepsis, Burn, Inflammation, Burn Infection
- Trial name
- NCT07866521
- Testing
- PSP Monitoring
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Texas Tech University Health Sciences Center
Burns, Burn Injury
Deepview HHF Training and Validation Study
The purpose of this Study is to help expand the use of the DeepView AI System so that it can assess burn injuries on the hands, head/face, and feet. To do this, the Study will collect new images of burns in these areas.
- Conditions
- Burns, Burn Injury, Diagnostic
- Trial name
- UK HHF (NCT07677657)
- Testing
- DeepView AI System
- Volunteers
- 280 people
- Sponsor
- SpectralMD
Burn Scar, Itch Scarring
Novel Strategies for Reducing Burn Scar Itch
The purpose of the study is to see whether using diphenhydramine (Benadryl), famotidine (Pepcid), and cromolyn sodium will decrease burn scar itch.
- Conditions
- Burn Scar, Itch Scarring, Wound
- Trial name
- NCT06801626
- Testing
- Famotidine and 4% topical cromolyn sodium
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Sepsis, Burns
Presepsin Diagnostic Performance in Severe Burn Sepsis
This study enrolls approximately 270 adult patients with severe burns covering at least 20% of total body surface area to evaluate how well the blood biomarker presepsin diagnoses sepsis early in this high-risk population.
- Trial name
- PSEP-BURNS (NCT07060560)
- Where
- South Korea
- Volunteers
- 138 people
- Sponsor
- Dohern Kym
Burn, Health Education
Gamified Approach To Burn Education
The goal of this clinical trial is to evaluate whether different educational strategies can improve knowledge acquisition regarding burn prevention and first aid among students enrolled in a community-based preparatory course.
- Conditions
- Burn, Health Education, Accident Prevention, First Aid
- Trial name
- NCT07404501
- Testing
- Serious Digital Game for Burn Prevention and First Aid, Face-to-Face Educational Lecture on Burn Prevention and First Aid
- Where
- Brazil
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital