Clinical trials: Brain Stimulation
Cognitive Change
Cerebral Excitability and Cognitive Performance
This study investigates the perceptual and cognitive influences of low-intensity electrical brain stimulation (transcranial direct current stimulation; tDCS), versus control (sham) conditions.
- Trial name
- NCT03807934
- Testing
- Stimulation via Soterix Medical or Neuroelectrics noninvasive brain stimulation systems
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Tufts University
Healthy Volunteers, no Condition, Basic Science
Transcranial Ultrasonic Neuromodulation of Primary Visual Cortex and Primary Auditory Cortex in Humans
There are a number of disorders of the brain that have limited treatment options, such as chronic pain, addiction, and major depression.
- Trial name
- NCT07508722
- Testing
- Transcranial Focused Ultrasound Stimulation, Electroencephalography, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
Asymptomatic Condition
Effects of Transcranial Direct Current Stimulation (tDCS) on Rotator Cuff Fatigue.
The aim of this study will be to determine the effects of active tDCS on rotator cuff fatigue. This study will be a randomized, double-blind, sham-controlled, cross-over clinical trial based on non-probabilistic sampling for…
- Trial name
- NCT05210231
- Testing
- Transcranial Direct Current Stimulation
- Where
- Argentina
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Gran Rosario
Healthy
Stimulating Deep Brain Regions With a Magnetic Stimulator
The purpose of this study is to determine whether a special coil designed for magnetic stimulation of areas deep in the brain can affect mood and emotion in healthy volunteers.
- Trial name
- NCT00063245
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Parkinson's Disease
Evaluation of the Effect of Repetitive Transcranial Magnetic Stimulation in Pain Perception in Parkinson's Disease
Pain is a frequent symptom in Parkinson's disease. Previous studies have shown that pain perception was altered in Parkinson's disease patients and could be related to nociceptive cortical area hyperactivation.
- Trial name
- rTMS (NCT01275573)
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Healthy
Real-time Monitoring of Motor Cortical Activity Induced by Low-frequency Repetitive Transcranial Magnetic Stimulation
In this study, we investigated the effect of low-frequency repetitive trans cranial magnetic stimulation, one of the noninvasive brain stimuli, on the functional changes of the bilateral motor cortical activity in normal subjects…
- Trial name
- NCT04019028
- Testing
- low frequency rTMS + Navigation System, only low frequency rTMS
- Where
- South Korea
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Depression
Brain Stimulation and Decision-making
Decision-making is an important process that is frequently shown to be impaired in patients with depression. While a number of preclinical and clinical studies have identified key regions involved in this process, it remains…
- Trial name
- NCT04099056
- Testing
- Neurostimulation
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Emory University
Idiopathic Parkinson's Disease
Facial Expression Recognition of Emotion and Categorization of Emotional Words in Parkinson's Disease. Impact of L-Dopa and Deep Brain Stimulation of Subthalamic Nucleus
Parkinson'disease is a neurodegenerative disorder characterised by bradykinesia, rigidity, rest tremor and postural instability.
- Trial name
- NCT00664157
- Testing
- Facial expression recognition of emotion
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Spatial Navigation
Modulating Goal-directed Navigation Using Noninvasive Brain Stimulation
Our specific aim is to examine the effects of TMS on spatial processing during goal-directed navigation. In these experiments the investigators will utilize a scalp-recorded brain oscillation called right posterior theta that is…
- Trial name
- NCT05801861
- Testing
- Active 10-Hz TMS to the parietal cortex, Active single pulse TMS to the parietal cortex
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Healthy Population
The Role of Beta Oscillation in Mental Time Travel
The project aims to study the neural basis of Mental Time Travel (MTT), i.e. the ability to travel back and forth in time. It has been proposed that the self-projection in time is similar to the self-projection in space…
- Trial name
- NCT04582994
- Testing
- Beta tACS, Alfa tACS
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Binge Eating, Inhibition, Psychological
Transcranial Magnetic Stimulation and Inhibitory Control Training to Reduce Binge Eating: Brain and Behavioral Changes
People with BE are characterized by high impulsivity, high levels of craving for high-calorie foods, deficits in inhibitory control, and maladaptive decision making.
- Trial name
- BE-NEMOIC (NCT06649994)
- Testing
- Active iTBS of the DLPFC, Active iTBS of the vmPFC, Computerized inhibitory control training
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Raquel Vilar López
Neuralgia
Towards Individualized Deep Brain Stimulation Treatment of Chronic Neuropathic Pain
Chronic neuropathic pain affects millions of individuals worldwide. It causes marked reduction of health, utility and quality of life and represents a considerable economic burden to society due to loss of work capacity and large…
- Trial name
- DBSforPain (NCT01899170)
- Testing
- Deep brain stimulation, Cervel Neurotech, Multi-coil TMS, 11C-Carfentanil
- Where
- Denmark
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Visual Acuity
Temporal Interference Brain Stimulation
The primary aim of this study is to translate temporal interference (TI) stimulation methodology into humans and examine its safety, feasibility, steerability, and focality.
- Trial name
- TI (NCT03747601)
- Testing
- Temporal Interference (TI) Stimulation
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Focal Epilepsy
TMS Combined With EEG/EMG as a Biomarker Predicting Antiepileptic Drug Response
Ιn the present study (BIOEPI), the following three hypotheses will be investigated: 1. The proposed TMS-EEG / EMG protocol (which includes software for calculating the cerebral cortex stimulation threshold) in combination with…
- Trial name
- BIOEPI (NCT05278221)
- Testing
- Software EstimLT
- Where
- Greece
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Aging
CONTROL Walking Study
Older adults often experience substantial deficits in walking ability, especially for walking tasks that are more complex such as obstacle crossing.
- Trial name
- NCT03790657
- Testing
- practice of a complex walking task, Active transcranial direct current stimulation (Active tDCS)
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Parkinson' Disease
Effects of Physical Exercise Combined With Transcranial Direct Current Stimulation in Parkinson's Disease
A controlled, blinded, and randomized clinical study will be carried out in a large sample of people with Parkinson's disease, where the combined effects of physical exercise and transcranial direct curren stimlation (tDCS) on…
- Trial name
- ExtDCSPARK (NCT07524400)
- Testing
- real tDCS and exercise, Exercise
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Spastic Cerebral Palsy
Evaluation of Multifocal Transcutaneous Electrical Stimulation for Self-treatment Among Children With Cerebral Palsy
The main purpose with this study is to investigate the effectiveness of a garment with integrated electrodes for multifocal transcutaneous electrical stimulation intended for treatment of spasticity in children with cerebral…
- Trial name
- NCT04078321
- Testing
- Mollii ®
- Where
- Sweden
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Sormland County Council, Sweden
Alzheimer Disease
The Dementia Study in Northern Norway
The Dementia Study in Northern Norway is an open controled intervention trial carried out in nine rural municipalities, five of which allocated to intervention and four to control.
- Trial name
- NCT00443014
- Testing
- Cognitive, physical and social stimulation
- Where
- Norway
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Dementia, Executive Function
The Effects of Transcranial Direct Current Stimulation on Executive Function in People With Mild to Moderate Dementia
To study the effects of transcranial direct current stimulation on executive function in people with mild to moderate dementia
- Conditions
- Dementia, Executive Function, Transcranial Direct Current Stimulation
- Trial name
- NCT03753191
- Testing
- transcranial direct current stimulation
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Elderly Subjects
Effects of Brain Stimulation During Nocturnal Sleep on Memory Consolidation in Elderly Healthy Subjects
The beneficial effect of nocturnal sleep on memory consolidation is well-documented in young, healthy subjects. Especially, periods rich in slow-wave sleep (SWS) have shown a memory enhancing effect on hippocampus-dependent…
- Trial name
- NCT01791790
- Testing
- Stimulation
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany