Clinical trials: Brain Fog, open to volunteers
Parkinson Disease
Smartshoes for Freezing of Gait in Parkinson's Disease
This is a pilot research study aimed at evaluating whether an FDA listed wearable shoe with capability to deliver vibration feedback can be safe and tolerable for patients with Parkinson disease and control participants and…
- Trial name
- NCT07001072
- Testing
- Smartshoes with haptic vibration feedback
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Stanford University
Parkinson Disease
Function-based Accelerated Stimulation Therapy (FAST-therapy) for Freezing of Gait (FOG) After Parkinson's Disease (PD)
Parkinson disease (PD) is a common disorder in which reduced speed of movement results from inadequate brain production of the chemical dopamine.
- Trial name
- NCT05509842
- Testing
- rTMS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan
Graves Disease, Mental Fatigue
Validating Immunological Markers Associated With Mental Fatigue in Graves' Disease
Mental fatigue occurs in many diseases and the reasons are mostly unknown. The investigators hypothesize that remaining mental fatigue after restored euthyroidism in Graves' disease is an autoimmune complication.
- Trial name
- NCT06081439
- Where
- Sweden
- Volunteers
- 430 people
- Sponsor
- Vastra Gotaland Region
COVID-19, Brain Fog
Transcranial Ultrasound Stimulation for Cognitive Function Modulation in Patients With Post COVID-19 Brain Fog
This study aims to investigate whether a specific brain region mediates the cognitive deficit in long COVID brain fog, and whether targeted modulation of this region can improve cognition.
- Conditions
- COVID-19, Brain Fog, Long COVID, Transcranial Ultrasound Stimulation
- Trial name
- NCT07154199
- Testing
- real transcranial ultrasound stimulation
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Xuanwu Hospital, Beijing
ADHD, Sleep Disturbance
A Study to Evaluate the Effects of a Supplement on the Side Effects Associated With Stimulant Medications
This is a hybrid, two-arm, triple-blind, placebo-controlled, randomized clinical trial evaluating the efficacy of the Stasis supplement on reducing oxidative stress, cortisol levels, and side effects associated with stimulant…
- Conditions
- ADHD, Sleep Disturbance, Brain Fog
- Trial name
- NCT07380412
- Testing
- Stasis Daytime and Nighttime
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Outliers, Inc.
Brain Fog, Cognitive Health
Modulation of the Brain Fog Scale by Eicosapentaenoic Acid Monoglycerides (MAG-EPA).
A growing body of studies shows that omega-3s act directly in molecular signaling pathways that reduce inflammation and are thought to have a positive effect on cognitive health.
- Trial name
- NBF-MG01 (NCT06695910)
- Testing
- Monoglyceride Eicosapentaenoic acid (omega-3), Sunflower Oil
- Where
- 2 sites in Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Samuel Fortin
Mental Fatigue, Athletic Performance
Mental Fatigue, Attentional Focus, and Countermovement Jump Performance
This study examines whether short-term mental fatigue and different jump instructions affect how high people can jump. Thirty-two physically active university students will complete two testing sessions in random order: one after…
- Trial name
- NCT07779304
- Testing
- Mental-Fatigue Protocol (Stroop Task), Control Protocol (Nature Video), No Prescribed Focus Instruction
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Inonu University
Graves Disease
The Impact of Person Centred Care (PCC) in Grave's Disease
Mental fatigue (MF) is prevalent after Graves' disease (GD), which is the most common form of hyperthyroidism. We have reported that 38% of patients, compared to 11% of control subjects, suffer from MF more than 1 year after…
- Trial name
- NCT06309316
- Testing
- Person-centred care (PCC)
- Where
- Sweden
- Volunteers
- 220 people
- Sponsor
- Vastra Gotaland Region
Burnout, Compassion Fatigue
The Effect of Mindfulness Meditation
Cancer is a disease that causes the most deaths worldwide and is challenging for patients and caregivers both physically and psychosocially.
- Conditions
- Burnout, Compassion Fatigue, Psychological Well-Being
- Trial name
- NCT06282913
- Testing
- Mindfulness Meditation
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Gulhane Training and Research Hospital
Neoplasm, Colorectal, Cognitive Impairment
Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy
The purpose of this research study is to see how the brain changes in patients receiving chemotherapy (cytotoxic drug) treatment for colon or rectal cancer at Parkview Cancer Institute.
- Conditions
- Neoplasm, Colorectal, Cognitive Impairment, Cognitive Dysfunction, Cognitive Change
- Trial name
- Chemo Brain (NCT05014399)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Joseph McCollom
Mental Fatigue
Monitoring the Effect of Mental Fatigue on Physical Performance Using Wearable Sensors and Physiological Parameters
Mental fatigue (MF) negatively affects both cognitive and physical performance, increasing the risk of errors in high-stakes environments such as sports and surgery.
- Trial name
- NCT07323810
- Testing
- Mental Fatigue
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Parkinson Disease, Freezing of Gait Symptoms in Parkinson Disease
TURN-IT FOG: Improving Turning and Freezing of Gait in People With PD
The goals of this clinical trial are to 1) learn how two different rehabilitation interventions for PD can reduce Freezing of Gait (FOG) in people with Parkinson's disease, as assessed by patients, clinicians, and wearable…
- Trial name
- NCT06815302
- Testing
- Experimental intervention, Active intervention
- Where
- 3 sites in United States, Brazil
- Volunteers
- 60 people
- Sponsor
- Oregon Health and Science University
Cognitive Performance, Attention
Effects of Caffeine on Chess Performance and Cognitive Function in Professional Chess Players
This study will examine whether caffeine improves cognitive and competitive performance in professional chess players during tournament-style games.
- Conditions
- Cognitive Performance, Attention, Reaction Time, Caffeine
- Trial name
- GRANDMASTER (NCT07641335)
- Testing
- Caffeinated Coffee
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Fatigue Symptom, Fatigue Intensity
Monitoring Fatigue In Daily Life In Adults With Cerebral Palsy or Acquired Brain Injury
The goal of this observational study is to learn about levels and patterns of fatigue in adults with cerebral palsy (CP) and acquired brain injury (ABI) in daily life.
- Conditions
- Fatigue Symptom, Fatigue Intensity, Cerebral Palsy (CP), Acquired Brain Injury Including Stroke
- Trial name
- NCT07135791
- Testing
- Real-time monitoring
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Burnout, Professional, Stress, Psychological
The Effect of Laughter Yoga on Individual and Organizational Outcomes in Nurse Managers
The goal of this clinical trial is to learn if laughter yoga can improve both individual and organizational outcomes in nurse managers.
- Conditions
- Burnout, Professional, Stress, Psychological, Compassion Fatigue, Quality of Life
- Trial name
- NCT07235735
- Testing
- Laughter Yoga Program
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Mental Fatigue
The Effect of Mental Fatigue on Upper Extremity Functional Performance
Mental fatigue (MF) is known to impair cognitive performance and may negatively affect physical performance. While its effects on lower-extremity functional performance have been investigated, little is known about the influence…
- Trial name
- NCT07645404
- Testing
- Mental Fatigue
- Where
- Belgium
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Izmir Bakircay University
Mental Fatigue
Effects of Cognitive Fatigue on Gait
The goal of this study is to comprehend how mental fatigue could affect human gait. The main questions to answer are: Does mental fatigue change how people walk? How long does it take for walking patterns to return to normal…
- Trial name
- NCT07710755
- Testing
- Mental fatigue
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Freezing of Gait Symptoms in Parkinson Disease
A System to Help With Freezing of Gait in Parkinson's Patients
The goal of this clinical trial is to learn if the ParkinSense system, a customizable, multimodal, and adaptable cueing system, can assist with freezing of gait (FOG) in patients with Parkinson's disease.
- Trial name
- NCT07542743
- Testing
- ParkinSense System
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Barron Associates, Inc.
Freezing of Gait, Parkinson Disease
Percept Transitions in FOG and PD
The purpose of this research is to examine the possible causes and signs of freezing of gait (FOG) secondary to Parkinson's disease (PD).
- Trial name
- NCT06848205
- Testing
- OFF Parkinson's Medication(s), OFF Deep Brain Stimulation
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Minnesota
Quiet Quitting, Fatigue, Compassion
Physical Fatigue, Compassion Fatigue, and Quiet Quitting in Physiotherapists
Physiotherapists are exposed to both physical and emotional demands due to the nature of their profession. Repetitive physical workload, prolonged standing, patient handling, and continuous interaction with patients may…
- Conditions
- Quiet Quitting, Fatigue, Compassion, Work Engagement
- Trial name
- NCT07340866
- Testing
- No Intervention (Observational Study)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University