Clinical trials: Blood Pressure, Low
Otherwise Healthy Individuals With Systolic Blood Pressure (SBP) From 110 to 139 mmHg and Low-density Lipoprotein Cholesterol (LDL-C) ≥ 100 mg/dL
A Study to Evaluate COR-2003 as Monotherapy and Co-Administered With COR-1004 in Adult Volunteers
This clinical trial has two parts. In Part A, the goal is to learn about the safety and tolerability of COR-2003 when it is given alone.
- Trial name
- NCT07858019
- Testing
- COR-2003, COR-1004 + COR-2003
- Where
- 2 sites in Australia, New Zealand
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Corsera Health
Sepsis, Low Blood Pressure
MID-STEP (MIDodrine for Sepsis Treatment and Early vasoPressor Weaning) Trial
This study is being done to determine if early administration of Midodrine can improve outcomes by maintaining a higher mean blood pressure off of intravenous medications.
- Trial name
- NCT06319248
- Testing
- Midodrine, Standard of Care
- Where
- 5 sites in United States
- Volunteers
- 308 people
- Sponsor
- Mayo Clinic
Blood Pressure, Low Back Pain
Therapeutic Mechanisms of Epidural Spinal Cord Stimulation
The purpose of this study in patients undergoing routine care epidural spinal cord stimulation (SCS) is to determine 1) whether SCS reduces arterial blood pressure (BP) in patients which chronic low back pain and hypertension, 2)…
- Conditions
- Blood Pressure, Low Back Pain, Hypertension
- Trial name
- NCT05556902
- Testing
- Permanent Epidural Spinal Cord Stimulation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Alabama at Birmingham
Low Blood Pressure, Delirium
Vasopressor SAT Study
To assess the impact of daily awakening from sedation on the amount of vasoactive medication required in the ICU. The hypothesis of this proposal is that the amount of vasoactive drug required to maintain an adequate mean…
- Conditions
- Low Blood Pressure, Delirium, Critical Illness
- Trial name
- NCT03182335
- Testing
- sedation awakening trial
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- University of Chicago
Blood Pressure, Hypertension
Validation Study of CART BP as a Wearable Cuffless Blood Pressure Monitor
This study aims to evaluate the accuracy of the CART BP, a medically approved ring-type blood pressure monitor, in comparison to the traditional auscultatory method using a dual-head stethoscope.
- Conditions
- Blood Pressure, Hypertension, Blood Pressure, High, Blood Pressure, Low
- Trial name
- NCT06513975
- Testing
- CART BP, sphygmomanometer
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sky Labs
Low Blood Pressure, Normal Blood Pressure
Clinical Trial of H2-BP Electronic Sphygmomanometer
The study compares H2-BP, a wristband blood pressure monitor, with an auscultatory sphygmomanometer. Both devices are used on the same arm.
- Conditions
- Low Blood Pressure, Normal Blood Pressure, Prehypertension, Hypertension
- Trial name
- NCT06491433
- Testing
- H2-BP
- Where
- South Korea
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Hemodynamic Instability, Blood Pressure, Low
Hemodynamic OptimizaTion in Sitting POsition Surgery Trial
Intraoperative hypotension (MAP <65 mmHg) in patients undergoing general anesthesia is a notable risk factor for the development of post-operative complications including acute kidney injury (AKI), myocardial injury, stroke and…
- Conditions
- Hemodynamic Instability, Blood Pressure, Low, Orthopedic Disorder
- Trial name
- HOTSPOT (NCT05143632)
- Testing
- ClearSight
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Non Communicable Diseases, Blood Pressure
Evaluation of the Ambuja Cement Foundation Noncommunicable Disease Program in Bathinda District of Punjab, India
This is an academic evaluation of a program being implemented by the Ambuja Cement Foundation (ACF). The aim of the evaluation is to determine the effect of the ACF noncommunicable disease (NCD) program on (1) fasting blood…
- Conditions
- Non Communicable Diseases, Blood Pressure, Behavior, Health, Blood Glucose, High
- Trial name
- NCT04827615
- Testing
- Ambuja Cement Foundation's Non Communicable Disease Program
- Where
- India
- Volunteers
- 11,322 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Cardiac Output, Low, Cardiac Output, High
Non-invasive Continuous Cardiac Output Monitoring in Preterm Infants Study
This is an observational study in newborn term and preterm infants. The study will validate if non-invasive continuous cardiac output monitoring is feasible in newborn infants, if normative values can be constructed and what is…
- Conditions
- Cardiac Output, Low, Cardiac Output, High, Blood Pressure
- Trial name
- NICCOM (NCT04064177)
- Testing
- NICAS cardiac output monitor
- Where
- United Kingdom
- Volunteers
- 148 people
- Sponsor
- Imperial College Healthcare NHS Trust
Blood Pressure, Low
Goal-Directed Fluid Therapy for Patients Undergoing Oro-Maxillofacial Surgery
Orthognathic surgery, one kind of Oro-maxillofacial surgery, is a complicate surgery that undergoes several hours with nasotracheal intubation general anesthesia.
- Trial name
- NCT03086694
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Hypertension, Nutritional Status
Hypertension DASH Diet and Salt Free Diet
Background: In the management of hypertension lifestyle changes are recommended along with pharmacological treatment. Aims: This randomized controlled intervention study aimed to compare the effects of a Dietary Approaches to…
- Conditions
- Hypertension, Nutritional Status, Diet, Healthy, Blood Pressure
- Trial name
- NCT06117072
- Testing
- diet plan
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nuh Naci Yazgan University
Ciprofol, Propofol
Comparing Ciprofol and Propofol for Sedation in Hypotensive ICU Patients: a Single Center Prospective Cohort Study
This study was a single-center, prospective, 2-year observational cohort study. The study subjects were ICU patients requiring vasopressor drugs and requiring sedation.
- Conditions
- Ciprofol, Propofol, Sedation, Low Blood Pressure
- Trial name
- NCT05971121
- Testing
- ciprofol
- Where
- China
- Volunteers
- 456 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Cardiac Output, Decreased Cardiac Output
Comparison of Hemodynamic Effects of Two Modalities of Alveolar Recruitment Maneuvers in Major Abdominal Surgery Patients
The objective of this study is to investigate the hemodynamic effects of two strategies of alveolar recruitment maneuver in patients undergoing major abdominal surgery in the operating room
- Conditions
- Cardiac Output, Decreased Cardiac Output, Hemodynamic Monitoring, Blood Pressure
- Trial name
- CHARM-Bloc (NCT05365113)
- Testing
- alveolar recruitment maneuver
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Clermont-Ferrand
Blood Pressure, Low
Induction Agent and Incidence of Hypotension in Heart Failure Patients Undergoing LVAD-Implantation
The induction of anesthesia is one of the most critical situations for high-risk-patients undergoing major surgery. For several reasons, it is crucial to maintain adequate blood pressure and cardiac output during this phase.
- Trial name
- INTENS (NCT04934410)
- Testing
- Etomidate, Midazolam, Sevoflurane
- Volunteers
- 50 people
- Sponsor
- Heidelberg University
Dementia, Alzheimer Disease
Effects of Remote-based Resistance Training on Cardiometabolic Risk Factors, Cognitive Function, and Quality of Life in Adults Living With Alzheimer's Disease and/or Related Dementias
The investigators aim to study the effects of a 24-week remote-based resistance exercise training program on cardiovascular disease risk factors, cognitive function, and quality of life in older adults living with mild cognitive…
- Conditions
- Dementia, Alzheimer Disease, Dementia, Vascular, Lewy Body Disease
- Trial name
- NCT05004558
- Testing
- Remote-based Resistance Exercise Training
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Drexel University
Low Blood Pressure, Blood Pressure
MediBeat - HeartBeat Observation Trial
The goal of the study was to compare the current gold standard blood pressure instrument (a mercury-filled sphygmomanometer with cuff and stethoscope) with the new experimental algorithm developed by HeartBeat Technologies Ltd.
- Conditions
- Low Blood Pressure, Blood Pressure, High Blood Pressure, Hypertension
- Trial name
- NCT04082819
- Testing
- Contec CMS50EW, Sphygmomanometer
- Where
- Canada
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- SE Health
Blood Pressure, Nervous System Diseases, Sympathetic
"Effects of Manual Lymphatic Drainage in the Neck in Healthy Subjects. Experimental Randomized Crossover Study"
Drainage manoeuvres described in different Manual Lymphatic Drainage methods, suggest modificactions in vital signs, by changes at nervous system, that would involve modifications to heart rate, breathing rate, blood pressure…
- Conditions
- Blood Pressure, Nervous System Diseases, Sympathetic, Heart Rate Low, Lymphatic Diseases
- Trial name
- NCT03709407
- Testing
- cervical stimuli, terminus, Control group
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Hypotension, Low Blood Pressure
Management of Hypotension In the Preterm Infant
The HIP trial is a large pragmatic, multinational, randomised trial of two different strategies for the management of hypotension in extremely low gestational age newborns (Standard with dopamine versus a restricted with placebo…
- Conditions
- Hypotension, Low Blood Pressure, Intraventricular Hemorrhage of Prematurity
- Trial name
- HIP (NCT01482559)
- Testing
- Dopamine hydrochloride, Dextrose 5%
- Where
- 10 sites in Belgium, Canada and 3 more
- Volunteers
- 58 people
- Sponsor
- University College Cork
Blood Pressure, Low Density Lipoprotein Cholesterol Level
Benefit of IQP-AS-118 on Blood Pressure and LDL-cholesterol
The purpose of this study is to evaluate the benefit and tolerability of IQP-AS-118 on the systolic and diastolic blood pressure (BP) and to explore the effects on parameters of lipid metabolism in subjects with elevated BP and…
- Trial name
- NCT02871362
- Testing
- IQP-AS-118
- Where
- Germany
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- InQpharm Group
Intraoperative Low Blood Pressure
A Effectiveness Trial of Early Hemodynamic Support in Patients Demonstrating a Low Systolic Blood Pressure
The investigators thus propose to use an innovative randomized effectiveness trial design to test the theory that early automatic identification of a ¡ Low Systolic Blood Pressure¡± clinical condition and decision-support alerts…
- Trial name
- NCT01654835
- Testing
- low blood pressure alert, standard of care
- Where
- United States
- Sponsor
- The Cleveland Clinic