Clinical trials: Blood Flow
High Flow Oxygen Therapy, ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION
High-Flow Nasal Oxygyen Therapy During Sedated Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration(EBUS-TBNA)
This study aims to evaluate the effects of high-flow nasal oxygen therapy on respiratory complications, blood gas parameters, and post-procedural recovery in patients undergoing sedated endobronchial ultrasound-guided…
- Conditions
- High Flow Oxygen Therapy, ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION, Sedation, Sedation Complication
- Trial name
- NCT07760727
- Testing
- High-Flow Nasal Oxygen Therapy, Conventional Oxygen Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Myocardial Blood Flow
Assessing Repeatability and Intra-individual Variability in [O15]H2O-PET Myocardial Perfusion Imaging
This study wish to assess the reproducibility of baseline and hyperemic myocardial blood flow as well as myocardial blood flow reserve measurements with [O15]H2O-PET-MPI.
- Trial name
- Heart-Wave (NCT06356857)
- Testing
- Myocardial perfusion imaging (MPI) using [O15]H2O-PET-CT
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Peter Hovind
Blood Flow Restriction Exercise, Resistance Training
Low Load With Blood Flow Restriction for Improving Strength, Balance, and Cognition in Older Adults
This study aims to examine the effects of low load resistance exercise with a blood flow restriction cuff on muscle strength, balance, physical performance, depression, and cognitive function in community-dwelling older adults.
- Conditions
- Blood Flow Restriction Exercise, Resistance Training, Elderly (People Aged 65 or More), Muscle Strength
- Trial name
- BFRT (NCT06962514)
- Testing
- Blood flow restriction cuff, Exercise without BFR cuff
- Where
- South Korea
- Volunteers
- 26 people
- Sponsor
- Sahmyook University
Frailty Syndrome, Older Adults
Feasibility and Effects of Inspiratory Muscle Training Combined With Blood Flow Restriction for Frail Older Adults
This randomized controlled trial study aims to evaluate the feasibility and preliminary efficacy of a combined inspiratory muscle training (IMT) and blood flow restriction (BFR) intervention in frail older adults.
- Conditions
- Frailty Syndrome, Older Adults, Blood Flow Restriction (BFR) Training Effects, Inspiratory Muscle Training
- Trial name
- NCT07573995
- Testing
- Exercise
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Medical University
Peripheral Arterial Hemodynamics, Lower Extremity Blood Flow
Doppler Ultrasound Evaluation of the Effects of Exercise Combined With Kinesiology Taping on Local Hemodynamic Parameters
This study aims to evaluate the effects of exercise combined with kinesiology taping on local hemodynamic parameters in healthy university students.
- Trial name
- Kinesio tape (NCT07858851)
- Testing
- Kinesiology Taping, Ankle Pumping Exercise
- Where
- Taiwan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Polyneuropathies, Regional Blood Flow
Comparative Effectiveness of Nursing Interventions: Using Buerger-Allen Exercises Versus Mechanical Compression Therapy on Lower Limb Perfusion and Peripheral Neuropathy Among Patients Undergoing Chemotherapy.
Chemotherapy-induced peripheral neuropathy (CIPN) and impaired lower-limb circulation are common adverse effects that can compromise patients' mobility, comfort, balance, functional independence, and quality of life and may…
- Conditions
- Polyneuropathies, Regional Blood Flow, Lower Extremity
- Trial name
- RCT (NCT07842237)
- Testing
- mechanical compression therapy, Exercises
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Damanhour University
Iliac Artery Occlusive Disease, Blood Flow Velocity
External Iliac Artery Endofibrosis in Cycling
A data request will be made regarding the tests conducted by the subject related to their performance, as well as the results of the medical diagnostic tests performed.
- Conditions
- Iliac Artery Occlusive Disease, Blood Flow Velocity, Performance, Cycling
- Trial name
- NCT07194330
- Where
- Spain
- Volunteers
- 1 people
- Sponsor
- Jesus Torres
Cerebral Blood Flow, APOE 4
A Nutritional and Pharmacological Intervention for Body, Brain, and Longevity Effects (NIBBLE)
The study aims to evaluate the safety, feasibility, and preliminary efficacy of the fasting-mimicking diet (FMD) or low-dose daily rapamycin treatment relative to a matched placebo control group when administered over 8 weeks in…
- Trial name
- NCT06682767
- Testing
- FMD1 (LNT22-017-1), Rapamycin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Cedars-Sinai Medical Center
Local Skin Blood Flow
Reproducibility of Photobiomodulation Induced Changes in Local Skin Blood Flow in Healthy Subjects
This study investigated whether near-infrared photobiomodulation (PBM), a non-invasive light therapy, can consistently increase blood flow in the skin of healthy adults.
- Trial name
- PBM (NCT07809464)
- Testing
- Near-infrared photobiomodulation (NIR PBM), Control (heat)
- Where
- Norway
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Ischemic Heart Disease (IHD), Cardiac Magnetic Resonance Imaging
The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study
This research aims to investigate whether symptoms of chest pain or shortness of breath among the study population are arising due to a heart problem, particularly any reduction of blood flow to the heart muscle from blockages in…
- Conditions
- Ischemic Heart Disease (IHD), Cardiac Magnetic Resonance Imaging, Myocardial Blood Flow
- Trial name
- SPINS2 (NCT06854458)
- Testing
- Quantitative Myocardial Blood Flow Evaluation, Qualitative Myocardial Blood Flow Evaluation, Gadavist
- Where
- 13 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Brigham and Women's Hospital
Prediabetes, Brain Insulin Sensitivity
Long-term Effects of Avocado Consumption on Health in Pre-diabetic Individuals
Primary aim of the study is to assess the effect of 12-week daily avocado consumption on cerebral blood flow and markers of cardio- and vascular health in both, the periphery and the brain, in pre-diabetic individuals with…
- Conditions
- Prediabetes, Brain Insulin Sensitivity, Cerebral Blood Flow, Satiety and Food Intake
- Trial name
- NCT07752225
- Testing
- Avocados
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- Maastricht University Medical Center
Surgical Flaps, Oral Surgical Procedures
Oral Flap Outline and Local Blood Supply After Surgical Removal of Lower Third Molar Teeth
Wisdom teeth in the lower jaw are frequently buried in bone and must be taken out surgically. To reach the tooth, the surgeon lifts the gum away from the bone as a flap, and the shape of that flap is left to the surgeon's…
- Conditions
- Surgical Flaps, Oral Surgical Procedures, Regional Blood Flow, Tooth, Impacted
- Trial name
- NCT07758192
- Testing
- Sulcular flap elevation for wisdom tooth removal, Three-cornered flap elevation for wisdom tooth removal
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Betül Taş Özyurtseven
Electromyographic Response to Blood Flow Restriction Exercise in Healthy Adults
Electromyographic Response to Blood Flow Restriction Exercise in Healthy Adults
This pilot randomized contralateral within-participant study evaluated the immediate neuromuscular response to low-load knee extension exercise performed with and without blood flow restriction in healthy young adults.
- Trial name
- NCT07654608
- Testing
- Bilateral low-load knee extension exercise protocol, Pneumatic blood flow restriction cuff
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad de Extremadura
Healthy, Brain Insulin Sensitivity
Long-Term Effects of Walnut Consumption on Brain Function
Rationale: Healthy foods, including mixed nuts, may improve brain function, which is essential for cognitive and metabolic health, and may contribute to improved food intake regulation.
- Conditions
- Healthy, Brain Insulin Sensitivity, Cerebral Blood Flow, Brain Vascular Function
- Trial name
- WalBrain (NCT07422220)
- Testing
- Walnuts
- Where
- Netherlands
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Blood Flow Restriction Exercise, Aging
Acute Autonomic Responses During and After BFR Training
The goal of this clinical trial is to compare how the body's nervous system responds to two different types of leg exercise in young and older adults.
- Trial name
- HOLD TIGHT (NCT07722403)
- Testing
- High-Intensity Resistance Training (HIRT), Low-Intensity Resistance Training with Blood Flow Restriction (LIRT-BFR)
- Where
- Portugal
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Blood Flow Restriction Training, Muscle Oxygenation
"How Blood Flow Restriction Exercise Affects Muscle Oxygenation and Lactate in Elite Athletes"
This study investigates the effects of blood flow restriction (BFR) training combined with low-intensity aerobic exercise on muscle oxygenation, total hemoglobin (THb), and blood lactate levels in elite athletes, comparing them…
- Conditions
- Blood Flow Restriction Training, Muscle Oxygenation, Physiological Adaptations
- Trial name
- NCT06918314
- Testing
- Blood Flow Restriction Kaatsu Training Device
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Exercise, Blood Flow Restriction (BFR) Training Effects
Effects of BFR-training on Stem Cells and Immune Cells in Human Skeletal Muscle
In this 3-year project, investigators will first measure stem cells (primary outcome) and immune cells (secondary outcome) in human skeletal muscle immediately after and 24 hour after the BFR-training.
- Conditions
- Exercise, Blood Flow Restriction (BFR) Training Effects, Supplement
- Trial name
- NCT07569627
- Testing
- BFR (180 mmHg), NMN-BFR exercise, Vitamin C-resistance exercise
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Taipei
Healthy Adult Participants, Bone Physiology
Postprandial Regulation of Bone Perfusion in Healthy Individuals
The goal of this clinical trial is to learn whether certain natural hormones - Glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide-2, (GLP-2), and amylin - affect blood flow to the bones.
- Conditions
- Healthy Adult Participants, Bone Physiology, Bone Blood Flow Regulation, Peptide Hormones
- Trial name
- GA-27 (NCT07679516)
- Testing
- isotonic saline infusion, Infusion of GIP(1-42), Infusion of GLP-2(1-33)
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Brain Blood Flow, Healthy
Blood Vessel Anatomy and Blood Flow Regulation
Brain blood flow regulation will be measured in response to environmental changes using MRI.
- Trial name
- NCT05396287
- Testing
- MRI
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Wisconsin, Madison
Control Condition, Pulmonary Disease (COPD), Chronic Obstructive
Acute Muscular and Vascular Responses to a Single Session of Exercise With BFR in COPD
Exercise training is a cornerstone of pulmonary rehabilitation (PR) in patients with chronic obstructive pulmonary disease (COPD). However, some patients derive limited benefits from conventional exercise programs.
- Conditions
- Control Condition, Pulmonary Disease (COPD), Chronic Obstructive, Blood Flow Restriction Training (BFRT)
- Trial name
- 2BFREE_aigu (NCT07668921)
- Testing
- Blood Flow Restriction, Standard exercise session
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Grenoble