Peripheral Arterial HemodynamicsKinesio tapeNCT07858851
Doppler Ultrasound Evaluation of the Effects of Exercise Combined With Kinesiology Taping on Local Hemodynamic Parameters
A study testing Kinesiology Taping and Ankle Pumping Exercise in people with Peripheral Arterial Hemodynamics and Lower Extremity Blood Flow, run by China Medical University Hospital at 1 site in Taiwan.
Trial summary
This study aims to evaluate the effects of exercise combined with kinesiology taping on local hemodynamic parameters in healthy university students. Doppler ultrasound will be used to assess local blood flow and hemodynamic responses associated with the intervention. Read more about this study
- Who is it for?
- Ages 20 to 30 yearsHealthy volunteers can take part
- Conditions the study is for
- Peripheral Arterial Hemodynamics, Lower Extremity Blood Flow
- What is being tested?
- Kinesiology Taping and Ankle Pumping Exercise
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 52 participants
- Where
- 1 siteTaiwan
- Study dates
- 1 Oct 2026to 31 Oct 2026
- Phase
- Interventional
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 30 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Healthy adults aged 20-30 years.
- Able to understand the study procedures and provide written informed consent.
Who cannot join
- History of cardiovascular disease, including hypertension, heart disease, or peripheral vascular disease.
- History of diabetes mellitus or other metabolic diseases that may affect vascular function.
- History of lower-extremity surgery or fracture.
- Acute lower-extremity musculoskeletal injury within the previous 6 months.
- Skin allergy or hypersensitivity to kinesiology tape.
- Current use of medications that may affect blood circulation or vascular function.
- Regular smoking.
- Pregnancy.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Taiwan1 site
Department of Physical Therapy, China Medical University
Taichung, 40407
Yueh-Ling Hsieh, PhD, 886-929122977, sherrie@mail.cmu.edu.tw
About this study
Official title: Acute Effects of Kinesio Taping Combined With Ankle Pumping Exercise on Peripheral Deep Arterial Hemodynamics: A Doppler Ultrasound Investigation
This study aims to evaluate the effects of exercise combined with kinesiology taping on local hemodynamic parameters in healthy university students. Doppler ultrasound will be used to assess local blood flow and hemodynamic responses associated with the intervention. Participants will perform the exercise protocol with kinesiology taping, and hemodynamic parameters will be assessed to determine whether the combined intervention produces changes in local circulation. The study is designed to provide a better understanding of the acute circulatory responses to exercise combined with kinesiology taping.
Read the detailed description
Kinesiology taping (KT) is commonly used to reduce swelling and promote local circulation. Fan-cut KT is thought to lift the skin and alter the space between the skin and underlying tissues, potentially affecting local blood and lymphatic circulation. Ankle pumping exercise produces repetitive contractions of the lower-leg muscles and may further influence peripheral circulation through the muscle-pump mechanism. However, the acute effects of KT alone and KT combined with ankle pumping exercise on deep arterial hemodynamics remain unclear.
This randomized controlled trial will investigate the acute effects of KT alone and KT combined with ankle pumping exercise on peripheral arterial hemodynamics in healthy adults. A total of 52 participants will be randomly allocated in a 1:1 ratio to either a kinesiology taping group (K group, n=26) or a kinesiology taping combined with ankle pumping exercise group (KE group, n=26).
Following baseline assessment, participants in both groups will receive fan-cut kinesiology taping around the ankle region. Participants in the KE group will additionally perform ankle pumping exercise consisting of approximately 2 seconds of ankle dorsiflexion followed by 2 seconds of plantar flexion. The exercise will be performed for five cycles, with each cycle consisting of 1 minute of exercise followed by 2 minutes of rest. Participants in the K group will rest without exercise during the corresponding period.
Doppler ultrasound will be used to assess hemodynamic responses in the anterior tibial artery and posterior tibial artery. Measurements will be obtained at baseline, immediately after kinesiology taping, and 15 minutes after the subsequent exercise or resting period. Hemodynamic parameters will include peak systolic velocity, end-diastolic velocity, mean velocity, time-averaged peak velocity, blood flow volume, resistive index, pulsatility index, and systolic/diastolic ratio.
The study will compare changes in arterial hemodynamic parameters between the two groups to determine whether adding ankle pumping exercise to kinesiology taping produces different acute hemodynamic responses compared with kinesiology taping alone.
- Being tested
- Kinesiology Taping, Ankle Pumping Exercise
- Keywords
- Kinesio Taping, Doppler Ultrasound, Ankle Pumping Exercise, Peripheral Hemodynamics
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Kinesiology TapingOther
Participants will perform ankle pumping exercise in a semi-reclined position with both lower limbs relaxed, the knees slightly flexed, and the heels supported. Each movement will consist of approximately 2 seconds of ankle dorsiflexion followed by 2 seconds of plantar flexion. The exercise will be performed for five cycles, with each cycle consisting of 1 minute of exercise followed by 2 minutes of rest. Participants will breathe normally and will be instructed to avoid breath-holding during the exercise.
Ankle Pumping ExerciseBehavioural
Participants will perform ankle pumping exercise in a semi-reclined position with both lower limbs relaxed, knees slightly flexed, and heels supported. Each movement will consist of approximately 2 seconds of ankle dorsiflexion followed by 2 seconds of plantar flexion. The intervention will consist of five cycles, with each cycle including 1 minute of exercise followed by 2 minutes of rest. Participants will breathe normally and avoid breath-holding during the exercise.
| Study group | Role | What they receive |
|---|---|---|
| Kinesiology Taping (K) | Experimental | Participants will receive fan-cut kinesiology taping around the ankle region. Two 12.5-cm kinesiology tape strips will be applied, with the anchor applied at 0% tension and the fan-shaped strips applied toward the foot at approximately 20% tension. Participants will rest without ankle pumping exercise during the intervention period. Receives: Other: Kinesiology Taping |
| Kinesiology Taping Combined With Ankle Pumping Exercise (KE) | Experimental | Participants will receive the same fan-cut kinesiology taping as the K group and will additionally perform ankle pumping exercise in a semi-reclined position. Each ankle movement will consist of approximately 2 seconds of dorsiflexion followed by 2 seconds of plantar flexion. The intervention will consist of five cycles, with each cycle including 1 minute of ankle pumping exercise followed by 2 minutes of rest. Receives: Other: Kinesiology Taping; Behavioral: Ankle Pumping Exercise |
What is being measured
The primary outcome is the main question the study is designed to answer.
Blood Flow Volume of the Lower-Limb Arteries
Blood flow volume will be measured using Doppler ultrasound in the anterior tibial artery (ATA) and posterior tibial artery (PTA). Measurements will be obtained under standardized conditions to evaluate acute changes in peripheral arterial blood flow following the intervention.
Measured: Baseline, immediately after kinesiology taping, and 15 minutes after the exercise or resting period
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Oct 2026
- Study start1 Oct 2026 (estimated)
- Primary completion31 Oct 2026 (estimated)
- Study completion31 Oct 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Peripheral Arterial HemodynamicsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants will be randomly assigned in a 1:1 ratio to one of two parallel groups: a kinesiology taping alone group (K group) or a kinesiology taping combined with ankle pumping exercise group (KE group). Each participant will receive only the intervention assigned to their group.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 52 participants (estimated)
Sponsor and investigators
- Lead sponsor
- China Medical University Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Yueh-Ling Hsieh, China Medical University, China
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07858851
- Sponsor's protocol ID
- CMUH114-REC1-232
- Other IDs
- NSTC115-2813-C-039-100-B
- Acronym
- Kinesio tape
- Status last verified
- Sep 2026
- First submitted
- 30 Sep 2026
- Last updated
- 5 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be publicly shared because the study protocol and informed consent do not include provisions for public sharing of individual-level participant data. Only aggregated and de-identified study results will be reported in publications or presentations.