Clinical trials: Blepharoplasty
Edema Face
Tacrolimus for Malar Edema
Elective lower eyelid surgery is a common cosmetic procedure. Facial swelling is a common complication. Studies suggest that this facial swelling is part of a complex inflammatory process.
- Trial name
- NCT03715387
- Testing
- Tacrolimus Topical 0.1% Topical Ointment, Polysporin Ointment
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Excess Skin of Both Eyelids, Contrast Sensitivity
The Effect of Upper Blepharoplasty on Vision Quality in the Early Postoperative Period
Contrast sensitivity (CS) and tear film (TF) changes are noted in late postoperative period after upper blepharoplasty (UB), while the same was rarely investigated in the early postoperative period.
- Conditions
- Excess Skin of Both Eyelids, Contrast Sensitivity, Tear Film Insufficiency of Both Eyes, Corneal Topography
- Trial name
- NCT05549713
- Testing
- Upper blepharoplasty
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- Osijek University Hospital
Injury Throat
Nasopharyngeal Versus Laryngeal Mask Airway in Anaesthesia for Bilateral Blepharoplasty
General anaesthesia demands securing patient's airway either with endotracheal tube or laryngeal mask (LMA); however, both carry the disadvantage of postoperative soar throat.
- Trial name
- NCT03510949
- Testing
- Nasopharyngeal airway or laryngeal mask airway
- Where
- Egypt
- Volunteers
- 148 people
- Sponsor
- Hala Salah El-Din El-Ozairy
Lower Eyelid Steatoblepharon (Excess Eyelid Fat)
Phase 2 Study of XAF5 (XOPH5) Ointment for Reduction of Excess Eyelid Fat (Steatoblepharon)
This study will test whether XAF5 (XOPH5) ointment, applied once daily to the lower eyelids for 10 weeks, reduces the prominence of lower eyelid fat in adults with moderate to severe steatoblepharon (excess eyelid fat).
- Trial name
- NCT02230761
- Testing
- XOPH5 Ointment
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Topokine Therapeutics, Inc.
Eyelid Diseases
Functional Changes After Upper Blepharoplasty
Upper blepharoplasty is a common eyelid procedure. It associated with visual, cosmetic and functional changes .Investigator will evaluate outcome of this procedure.
- Trial name
- NCT04201925
- Testing
- upper blepharoplasty
- Where
- United Arab Emirates
- Volunteers
- 50 people
- Sponsor
- Benha University
Ptosis, Eyelid
Effect of Eyelid Patching After Ptosis Surgery
The goal of this randomized, controlled, observer-blinded study is to compare the effect of compression dressing after ptosis surgery.
- Trial name
- NCT05770973
- Testing
- Compression dressing (build by Kompressen, gauze swabs, Nobamed Paul Danz AG, Wetter, Germany and NOBALUMENAL® - steril, eye pad, Nobamed Paul Danz AG, Wetter, Germany
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Augenklinik LMU
Eyelid Diseases, Ptosis, Eyelid
Telemedicine Follow-up for Routine, Low-Risk Oculoplastic Surgery
The investigators propose utilizing a simple telemedical protocol to allow patients to substitute the first post-operative visit with a remote survey that includes essential post-operative history, vision measurement, and…
- Conditions
- Eyelid Diseases, Ptosis, Eyelid, Blepharoptosis, Dermatochalasis
- Trial name
- NCT04235803
- Testing
- Telemedicine follow-up
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of California, San Francisco
Eyelid Diseases, Ptosis, Eyelid
Effect of Upper Eyelid Surgeries on Corneal Characteristics
The goal of this prospective observational study is to learn about the impact of conventional eyelid correction surgery on the eye's health and function in ptosis and eyelid retraction patient.
- Trial name
- NCT05750251
- Testing
- levator muscle resection surgery, Müller's muscle-conjuctival resection surgery, full-thickness anterior blepharotomy surgery
- Where
- Taiwan
- Volunteers
- 13 people
- Sponsor
- National Taiwan University Hospital
Dermatochalasis, Blepharoplasty
Electrocautery Versus Scalpel Incision in Upper Eyelid Blepharoplasty
This prospective randomized contralateral comparative study aims to compare electrocautery and scalpel incision techniques in upper eyelid blepharoplasty.
- Trial name
- ELECT-BLEPH (NCT07749846)
- Testing
- Electrocautery incision, Scalpel incision
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Beyoglu Eye Research and Education Hospital
Dermatochalasis of Upper Eyelid
Does Unilateral Compression Dressing Reduce Postoperative Swelling and Bruising After Upper Eyelid Blepharoplasty?
This study evaluated whether applying a compression dressing to one eyelid after upper eyelid blepharoplasty (eyelid lift surgery) reduces swelling, bruising, and discomfort compared to the untreated eyelid.
- Trial name
- COMPRESS-BLEPH (NCT07701265)
- Testing
- Compression Dressing (CD), No Dressing (Standard Postoperative Care)
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Fatma Poslu Karademir
Pain, Postoperative, Bruising
Use of Tranexamic Acid in Blepharoplasties
The goal of this investigation is to assess whether or not there is a significant difference in the presence and/or degree of post-operative ecchymosis, pain, and edema between groups of patients undergoing upper lid…
- Trial name
- NCT04724772
- Testing
- Tranexamic acid injection
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Subbrow Blepharoplasty;Double Eyelid Surgery； Orbicularis Oculi Muscle
Subbrow Blepharoplasty Combined With Double Eyelid Surgery for Upper Eyelid Rejuvenation in Asian Women
Subbrow blepharoplasty combined with double eyelid surgery excising the subbrow skin and the supratarsal upper eyelid skin, lifting and fixing the OOM flap, meanwhile restoring the natural and symmetrical appearance, is a safe…
- Trial name
- NCT04001660
- Testing
- Subbrow Blepharoplasty Combined with Double Eyelid Surgery
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Lower Eyelid Entropion
Minimally Invasive Holmium:YAG Laser Blepharoplasty
The purpose of this research study is to is to evaluate the safety and effectiveness of the FDA approved Holmium:YAG laser for reducing lower eyelid bags.
- Trial name
- NCT00842764
- Testing
- Holmium: YAG laser
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Dermatochalasis, Ptosis, Eyelid
A Comparison of the Effect of Suture Material on Blepharoplasty Incision
The objective is to compare the effect of suture material on blepharoplasty incision. Outcomes of blepharoplasty scar and/or cosmesis will be compared between plain gut and polypropylene suture.
- Trial name
- NCT04585217
- Testing
- Randomized laterality of suture materials for closure (6-0 polypropylene monofilament suture vs fast absorbing gut suture on right eyelid)
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Other Degenerative Disorders of Eyelid and Periocular Area
Botulinum Toxin to Improve Lower Blepharoplasty Scar
The combination of Botulinum toxin for crow feet (lateral part of orbicularis oculi muscle) and lower blaphaloplasty might have reduces the tension on the end of lower blaphaloplasty incision whereas the scar is more visible on…
- Trial name
- NCT02786550
- Testing
- Botulinum Toxin, Normal Saline
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Lower Eyelid Bags
The Effect of Inhalation Aromatherapy on Intraoperative Fear in Patients Undergoing Lower Blepharoplasty Under Local Anesthesia: A Randomized Controlled Trial
This study is a single-center, randomized, controlled, open-label clinical trial designed to evaluate the intervention effect of inhaled aromatherapy on intraoperative fear in patients undergoing lower blepharoplasty (eyelid bag…
- Trial name
- NCT07766902
- Testing
- inhaled aromatherapy
- Where
- China
- Volunteers
- 152 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Dermatochalasis of Upper Eyelid, Blepharoplasty
Perioperative Haemostasis, Procedure-Related Pain After Physiological or Pharmacological Modifications of Local Anaesthesia Around the Eyes
The goal of this clinical trial is to determine whether buffering, warming, or addition of hyaluronidase or tranexamic acid to lignocaine during eyelid injection of local anaesthesia reduce injection pain and procedure-related…
- Trial name
- P4LE (NCT07734740)
- Testing
- Sodium Bicarbonate (NaHCO3), Warmed lignocaine, Hyaluronidase Injection
- Where
- 3 sites in Hong Kong
- Volunteers
- 80 people
- Sponsor
- Prince of Wales Hospital, Shatin, Hong Kong
Eyelid Diseases
Brassiere Brow Suture and Internal Browpexy
Brow ptosis is a common problem. internal browbexy and brassier suture are common surgical approach
- Trial name
- NCT04861454
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- Benha University
Brow Ptosis, Dermatochalasis
Enhancing the Durability of Thread-Assisted Brow Suspension Through Upper Blepharoplasty-Assisted Ligament Release
This prospective clinical study aims to investigate whether combining upper blepharoplasty with limited release of the lateral brow-retaining ligaments improves the long-term effectiveness of barbed thread brow suspension.
- Conditions
- Brow Ptosis, Dermatochalasis, Periorbital Aging
- Trial name
- NCT07879456
- Testing
- Upper Blepharoplasty, Barbed Thread Brow Suspension, Lateral Brow-Retaining Ligament Release
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Muhammed Mustafa Demirok
Eye Disorders
Dry Eye in Upper Eyelid Surgery: Muscle Versus Fat Removal
The aim of this study is to compare the effects of two different surgical techniques (Orbicularis Oculi excision and Orbicularis Oculi + Fat excision) applied in upper blepharoplasty surgery on dry eye and to evaluate the effects…
- Trial name
- NCT06985264
- Testing
- Upper Eyelid Blepharoplasty surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people
- Sponsor
- Mersin Training and Research Hospital