Clinical trials: Biopsy/Methods
Interstitial Lung Disease
Integration of Cryobiopsies for ILD Diagnoses- Experience Based on 250 Biopsy Procedures.
A retrospective study on safety and Diagnostic yield in using cryobiopsies as a Diagnostic tool in diagnosing patients under investigation for Interstitial lung diseases.
- Trial name
- NCT05311345
- Volunteers
- 250 people
- Sponsor
- Aarhus University Hospital
Prostate Cancer
Does End-fire Technique Increase Detection Rate of Prostate Cancer at First Re-biopsy Compared to Side-fire Technique?
Prostate cancer is the most common cancer among men in Sweden. During investigation of suspected cancer transrectal ultrasound with needle biopsies from prostate leeds to diagnosis.
- Trial name
- NCT02761135
- Where
- Sweden
- Volunteers
- 364 people
- Sponsor
- Kronoberg County Council
Cancer
Pan-canceR Early-Stage deteCtion by lIquid Biopsy tEchNique projecT
PRESCIENT is a multi-center, prospective observational study aimed to detect cancers early by combined assays for serum protein markers and cell-free DNA (cfDNA) methylation markers. Blood RNA markers will also be evaluated.
- Trial name
- PRESCIENT (NCT04822792)
- Testing
- Multi-cancer early detection test
- Where
- China
- Volunteers
- 11,879 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Pancreas Mass Diagnosis
Comparing Methods to Biopsy Pancreas Mass
This study will examine whether there is any difference in number of passes needed to diagnose pancreatic masses during endoscopic ultrasound-guided biopsies using 2 different types of needles.
- Trial name
- NCT01663493
- Testing
- FNB
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Brigham and Women's Hospital
Breast Carcinoma, Sentinel Lymph Node Biopsy
Does Ultrasound Guidance Axillary Incision Improve Sentinel Lymph Node Detection in Breast Cancer?
This single-center randomized controlled trial evaluates whether detecting the first lymph node at the axillary entrance with ultrasound guidance, followed by a targeted axillary incision over the pencil-marked projection…
- Trial name
- NCT07338721
- Testing
- Ultrasound-guided axillary incision group, The standard axillary incision
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Antalya Training and Research Hospital
CT-guided Minimally Invasive Procedures e.g., Biopsies
Evaluation of the Safety, Effectiveness & Usability of the XACT Robotic System for Image Guided Percutaneous Procedures
This is a prospective, single-arm study is to evaluate the safety, effectiveness and usability of the XACT device. Subjects undergoing CT-guided, minimally invasive percutaneous procedures in the interventional radiology suite…
- Trial name
- NCT03008603
- Testing
- XACT Robotic System
- Where
- 2 sites in United States, Israel
- Volunteers
- 60 people
- Sponsor
- Xact Robotics Ltd.
Liver Disease
Comparing Pain in Patients Undergoing Percutaneous Versus Transjugular Techniques of Liver Biopsy
Background: In a liver biopsy, a small piece of liver is removed. A percutaneous liver biopsy (PLB) is done through a needle on the right side of your belly.
- Trial name
- NCT02311348
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Pain
Does Trans-Cutaneous Electrical Nerve Stimulation (TENS) Alleviate The Pain Experienced During Bone Marrow Sampling?
The approach of this study will be to answer the question does high-frequency stimulation Trans-Cutaneous Electrical Nerve Stimulation (TENS) alleviate the pain experienced during the bone marrow sampling procedure in addition to…
- Trial name
- TENS (NCT02005354)
- Testing
- Trans-cutaneous Electrical Nerve Stimulation (TENS), Standard pain relief (ie. local anaesthetic with or without inhaled nitrous oxide)
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- University Hospital Plymouth NHS Trust
Endoscopy, Colonoscopy
Retrospective Review of Gastrointestinal System Endoscopy Procedures
The aim of the study is retrospectively evaluating all features of endoscopic and pathological diagnoses of cases who underwent upper and lower gastrointestinal endoscopy.
- Conditions
- Endoscopy, Colonoscopy, Gastroscopy, Colonic Polyps
- Trial name
- RRGIE (NCT05012527)
- Where
- Turkey (Türkiye)
- Volunteers
- 15,448 people
- Sponsor
- Istanbul Sultanbeyli State Hospital
Lung Neoplasms, Liver Neoplasms
A Comparison of Methods for Assisting Needle Angle Selection During Image-guided Tissue Biopsy
Background: Currently, standard procedures for biopsies that are guided by computed tomography (CT) imaging involve CT scans and a computer program to plan and illustrate where the physician will place the needle to obtain the…
- Conditions
- Lung Neoplasms, Liver Neoplasms, Kidney Neoplasms, Cancer
- Trial name
- NCT01218854
- Testing
- Needle angle measurement
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Leukemia
Use of Lipid Emulsion or Nanoemulsion of Propofol on Children Undergoing Ambulatory Invasive Procedures.
The purpose of this study is to compare the safety and efficacy of the of propofol nanoemulsion and lipid emulsion for sedation in non-invasive ambulatory procedures.
- Trial name
- NCT01326078
- Testing
- propofol
- Sponsor
- Cristália Produtos Químicos Farmacêuticos Ltda.
Hepatic Disease, Renal Disease
Assess Safety and Performance of the Kronos Electrocautery Device for Electrocautery Procedures Following Coaxial Biopsy Procedures
The primary objective for this study is to assess safety and performance of the Kronos Electrocautery Device for electrocautery procedures following coaxial biopsy procedures on areas that include, but are not limited to, liver…
- Trial name
- NCT05593211
- Testing
- Kronos Electrocautery Device
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Single Pass Inc
Mediastinal Lymph Node Enlargement, Sarcoidosis
Bronchoscopic Sampling Techniques in Sarcoidosis
The development of endobronchial ultrasound (EBUS) and EBUS-guided transbronchial needle aspiration (EBUS-TBNA) has improved the safety and diagnostic accuracy of the mediastinal lymph node (MLN) sampling.
- Conditions
- Mediastinal Lymph Node Enlargement, Sarcoidosis, Tuberculosis, Lymphomas
- Trial name
- NCT01836822
- Testing
- EBUS guided transbronchial forceps biopsy (EBUS-TBFB), EBUS guided transbronchial needle aspiration (EBUS-TBNA), large bore (19G) histologic needle biopsy of the mediastinal lymph nodes
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Medical University of Warsaw
Anxiety
Empathy and Standard Diagnostic Procedures in an Outpatient Breast Clinic Might Not be Enough
The project investigates prospectively whether anxiety in the context of breast biopsy can be reduced by the planed intervention (take-home brochure and structured and standardized information given by a psychologically trained…
- Trial name
- NCT02796612
- Testing
- no intervention, delivery of a take-home brochure, patient care by a psychologically trained physician
- Where
- 3 sites in Switzerland
- Volunteers
- 250 people
- Sponsor
- University Hospital, Basel, Switzerland
Pain
EMLA Cream as Analgesic for Outpatient Gynecological Procedures
The goal of this clinical trial is to compare pain perception in the study participant population undergoing the following gynecological procedures: Intra Uterine Device (IUD) insertion, hysteroscopy, and endometrial biopsy and…
- Trial name
- NCT05970354
- Testing
- EMLA Cream, VersaPro Cream Base for Compounding
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- CAMC Health System
Endometrial Cancer, Lymphadenectomy
Comparison of Transvaginal Paracervical and Transperitoneal Approaches in Lymphadenectomy During v-NOTES Surgery for Patients Diagnosed With Endometrial Cancer
The aim of this study is to compare two types of lymphadenectomy (transperitoneal vs. paracervical) during the lymphadenectomy phase of endometrial cancer staging surgery performed using V-NOTES, a new and advanced technique.
- Conditions
- Endometrial Cancer, Lymphadenectomy, Sentinel Lymph Node Biopsy, Minimally Invasive Surgical Procedures
- Trial name
- ENDONOTE (NCT06870903)
- Testing
- Extraperitoneal(transvaginal paracervical sentinel lymphadenectomy) group lymphadenectomy, Transperitoneal lymphadenectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Infertility, Female, IVF
The Study of the Implantation Window From Endometrial Biopsy With Gene Expression Methods
The objective of the study is to gain a better understanding of the gene expression changes in the endometrial biopsy especially whether the endometrium has reached a receptive status, i.e. the implantation window, or not.
- Trial name
- NCT04052464
- Testing
- endometrium biopsy, endometrium lavage, repeated endometrium lavage
- Volunteers
- 67 people
- Sponsor
- Prelife Kft
Carcinoma, Non-Small-Cell Lung, Pathology, Molecular
Influence of Biopsy Technique on Moleculargenetic Tumor Characterisation in NSCLC
Study design Prospective multicentre explorative randomized single blinded study to evaluate accuracy of molecular genetic characterisation of NSCLC.
- Trial name
- PROFILER (NCT03971175)
- Testing
- Forceps biopsy, Cryobiopsy
- Where
- Germany
- Volunteers
- 540 people
- Sponsor
- University Hospital Tuebingen
Needle Biopsy
Intelligent Optical Probe for Guiding Core Needle Biopsy Procedures
To learn if an investigational imaging device can help to identify tumor tissue before a biopsy is taken.
- Trial name
- NCT06199492
- Testing
- tVisio-1
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- M.D. Anderson Cancer Center
Helicobacter Pylori Infection
Gastric Swab for Helicobacter Pylori Detection
A randomized controlled trial for comparing the Helicobacter pylori test using the swap method and the method using the conventional biopsy.
- Trial name
- NCT05349578
- Testing
- swab RUT
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Seoul National University Hospital