Clinical trials: Biomonitoring
Occupational Exposure
Sevoflurane Human Biomonitoring in Operating Room Personnel
Sevoflurane is a widely used volatile agent for induction and maintenance of anaesthesia. The administration of sevoflurane involves the risk of occupational exposure.
- Trial name
- NCT03891316
- Testing
- HFIP and Sevoflurane are measured after 3 consecutive days of work.
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Product Use
Study of Exposure to Chemicals in Consumer Products
Background: In a lifetime, a person may encounter tens of thousands of chemicals used as ingredients in the products they buy. It s not easy to measure them because the companies that sell the products don t have to tell the…
- Trial name
- NCT02471365
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Asthma
Biological Monitoring of Nano Sized Particles in the Airways of Asthmatic Children
Background Ambient airborne particulate material (PM) is defined according the aerodynamic diameter into coarse, fine, and ultrafine or "nano" sized particles ranging between 2.5-10 µm (coarse), <2.5 µm (fine), and <0.1 µm…
- Trial name
- EHF (NCT01754948)
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Chronic Iron Overload
Survey to Assess Physicians' Knowledge of Exjade Posology and Biological Monitoring Recommendations as Described in the Educational Materials
The objective of this survey is to assess the knowledge of HCPs in relation to the recommended posology and biological monitoring for Exjade, based on the current locally valid Exjade educational materials (including the…
- Trial name
- NCT06215287
- Testing
- Physician survey
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- Novartis Pharmaceuticals
Obesity
Mobile Device Biomonitoring to Prevent and Treat Obesity in Underserved Youth
This project proposes to use mobile devices to develop new tools for pediatric obesity prevention and treatment targeting underserved minority adolescent populations at high risk for obesity and related diseases.
- Trial name
- KNOWME (NCT02017223)
- Testing
- Knowme Device Wear
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Cadmium, Placenta
Cadmium Exposure During Pregnancy and Fetal Growth
Cadmium is a toxic heavy metal naturally present in the environment, whose human exposure has increased over recent decades due to diffuse anthropogenic contamination, particularly related to industrial activities and the use of…
- Conditions
- Cadmium, Placenta, Fetal Growth, Birth Weight
- Trial name
- CADNAT (NCT07855237)
- Testing
- maternal blood samples, Placental tissue samples, maternal urine samples
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Cardiorenal Syndrome, Acute Decompensated Heart Failure
Biomonitoring and Cardiorenal Syndrome in Heart Failure(BIONICS-HF) Trial
The purpose of this study is to evaluate the ability of a non-invasive monitor that measures how much fluid is in the body as well as various blood tests for their ability to predict worsening kidney function in patients with…
- Trial name
- BIONICS-HF (NCT01570153)
- Where
- 2 sites in United States, Italy
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
ANCA Associated Vasculitis (AAV), Polyangiitis (GPA)
Comparison of a Strategy Based on Clinico-biological Monitoring Versus Pre-emptive Rituximab Treatment in Cases of ANCA Reappearance in Granulomatosis With Polyangiitis and Microscopic Polyangiitis.
The PREP-ANCA study seeks to establish a more personalized treatment strategy for ANCA-associated vasculitides by assessing the efficacy of pre-emptive rituximab administration upon ANCA repositivity in preventing relapses in…
- Conditions
- ANCA Associated Vasculitis (AAV), Polyangiitis (GPA), Microscopic Polyangiitis (MPA)
- Trial name
- PREP-ANCA (NCT07451847)
- Testing
- Rituximab
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Occupational Exposure, Genotoxicity
Biomonitoring of Occupationally Populations Exposed to Micro and Nanoplastic
The biomonitoring study aims to evaluate genotoxic damage and other parameters of exposure in different occupational exposed populations that work directly with different plastics.
- Conditions
- Occupational Exposure, Genotoxicity, Damage Dna
- Trial name
- NCT06323603
- Testing
- Micro and nanoplastic
- Where
- 4 sites in Finland, Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ricard Marcos
Myocardial Infarction, Myocardial Infarction, Acute
BIO monitorinG in Patients With Preserved Left ventricUlar Function AfteR Diagnosed Myocardial Infarction
The BIO|GUARD-MI study investigates whether continuous arrhythmia monitoring and the consequent treatment after detected arrhythmias in patients after myocardial infarction with preserved cardiac function, but other risk factors…
- Conditions
- Myocardial Infarction, Myocardial Infarction, Acute, Myocardial Infarction Old
- Trial name
- BIO-GUARD-MI (NCT02341534)
- Testing
- BioMonitor
- Where
- 59 sites in United States, Australia and 12 more
- Volunteers
- 802 people
- Sponsor
- Biotronik SE & Co. KG
Pesticides, Occupational Exposure
Fungicide Exposure Assessment Among Apple and Peach Farmers in the Argicultural Health Study
This protocol describes an exposure assessment study of farmers in North Carolina and Iowa who personally apply the fungicides captan, thiophanate-methyl, and benomyl to apple and peach orchards.
- Trial name
- NCT00342394
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- National Cancer Institute (NCI)
Pregnancy Related, Pregnancy Complications
The Heartland Study
The Heartland Study is a prospective, observational study that will enroll up to 2,600 pregnant participants across the Heartland States in the U.S..
- Conditions
- Pregnancy Related, Pregnancy Complications, Birth Defect, Gestational Age and Weight Conditions
- Trial name
- NCT05492708
- Where
- 4 sites in United States
- Volunteers
- 2,600 people, healthy volunteers welcome
- Sponsor
- Heartland Health Research Alliance
Congestive Heart Failure
Aetna_Intel Medicare Home Biomonitoring Study
The hypothesis is that use of Internet-connected home biomonitoring of weight, blood pressure and other indicators, in conjunction with nurse case management, will result in improved outcome for Medicare beneficiaries with with…
- Trial name
- NCT01105572
- Testing
- Intel Health Guide, Case Management
- Where
- United States
- Volunteers
- 316 people
- Sponsor
- Aetna, Inc.
Environmental Exposure
Behavioural Intervention to Decrease Exposure to Emerging Chemical Pollutants
The purpose of this study is to evaluate the effectiveness of a behavioural intervention designed to reduce exposure to environmental chemical pollutants among adults in Spain.
- Trial name
- INPOL (NCT07465315)
- Testing
- Guidelines from the public healthcare system, INPOL healthy lifestyle informative guidelines
- Where
- 5 sites in Spain
- Volunteers
- 740 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Hodgkin Lymphoma
Circulating Tumor DNA Genotyping for Biological Monitoring of Patients Treated in the FIL-Rouge Clinical Trial
Prospective, multicenter, non-interventional, biological study ancillary to FIL-Rouge clinical trial (NCT03159897) enrolling patients affected by Advanced-stage Hodgkin Lymphoma, ABVD-based upfront treatment in 19 centers in…
- Trial name
- FIL-RougeBIO (NCT05066555)
- Where
- 13 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Italiana Linfomi - ETS
Dermal Exposure, Inhalative Exposure
Application of Plant Protection Products (PPP) in Apple Orchards
The aim of the aPPPle pilot study is to test feasibility and generate first results in preparation for a main study. The aPPPle study will investigate the exposure of operators, workers and residents to plant protection products…
- Conditions
- Dermal Exposure, Inhalative Exposure, Metabolites in Urine, Effekt Biomarker in Blood
- Trial name
- aPPPle (NCT06884189)
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- German Federal Institute for Risk Assessment
Heart Failure
Biological Monitoring by a Nurse for Heart Failure Patients.
The aim of this study is to evaluate the feasibility and safety of delegating remote biological monitoring in post-hospitalization for cardiac decompensation by a heart failure nurse.
- Trial name
- IC-SPEC (NCT05782075)
- Testing
- Remote biological monitoring by a heart failure nurse
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hôpital NOVO
Malnutrition Pregnancy, Malnutrition in Children
Early Life Malnutrition, Environmental Enteric Dysfunction and Microbiome Trajectories
Malnutrition in women of reproductive age remains a public health concern in Sub-Saharan Africa (SSA). Malnutrition during pregnancy affects foetal growth with a tendency of the exposed infants to also develop it.
- Conditions
- Malnutrition Pregnancy, Malnutrition in Children, Malnutrition (Calorie), Environmental Enteric Dysfunction
- Trial name
- UZBCS-2 (NCT07195006)
- Testing
- Malnutrition in pregnancy as exposure, Poor WASH living conditions as exposure
- Where
- Zimbabwe
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- University of Zimbabwe
Mycotoxin Biomonitoring
How Healthy Are Your Oats?
Oat foods are commonly consumed as healthy breakfast options and their nutritional value is well recognised. Oats are a rich source of fibre, micronutrients and non-nutrient bioactive compounds, but at the same time cereals…
- Trial name
- HISU_101 (NCT07050680)
- Testing
- Dietary intervention
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Smoking
Using Smartwatches to Monitor Smoking in Real-life Situations
Background: It is important to quickly identify when people are at risk of smoking. Most current methods rely on people reporting when they smoke or what makes them want to smoke.
- Trial name
- NCT07067151
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute on Minority Health and Health Disparities (NIMHD)