Clinical trials: Bilateral Cataract
Cataract
Comparison of a New EDOF-IOL With a Standard-EDOF-IOL
Comparison of the new extended depth of focus (EDOF) intraocular lens (IOL) ARTIS ACTIVE, which is designed as a twinset of IOLs, with the standard EDOF IOL AT Lara .
- Trial name
- NCT03921762
- Testing
- Cataract surgery with Artis Active IOLs, Cataract surgery with AT Lara IOLs
- Where
- Austria
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Cataract
Visual Function After Implantation of Bilateral AcrySoft ReSTOR Aspheric IOL
This study will involve up to 20 bilateral patients per surgeon. Patients will be assessed pre-operatively, and at subsequent visits (following the implantation of the intraocular lens in the second eye) at 1 week, 1 month, 3…
- Trial name
- NCT00934622
- Testing
- AcrySof® ReSTOR® Aspheric IOL
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Alcon Research
Cataract
Bilateral Monofocal Versus Monofocal-EDOF IOL Implantation: Quality of Vision Comparison
The goal of this clinical trial is to compare visual quality after cataract surgery between two groups: bilateral monofocal intraocular lenses (IOL) and monofocal and contralateral extended depth-of-focus (EDOF) IOL implantation.
- Trial name
- COMEDI (NCT06002399)
- Testing
- cataract surgery
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Cataract
Visual Function and Patient Satisfaction After Bilateral Implantation of AcrySof Natural ReSTOR (Model SN60D3) or AcrySof Natural Monofocal (Model SN60AT)
The purpose of the study is: to compare visual parameters (Subjective refraction and Visual Acuity (VA)) and safety (tilt, decentration and posterior chamber opacification (PCO)) in a prospective series of 40 patients after…
- Trial name
- NCT00759668
- Testing
- Acrysof Natural ReSTOR SN60D3, Acrysof Natural Monofocal SN60AT
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Alcon Research
Cataract, Aphakia - Lens Capsule Present
Visual Adaptation and Quality of Life After Different IOL Implantation Strategies
This longitudinal observational study aims to evaluate long-term visual adaptation trajectories, optical quality, and patient-reported outcomes in age-related cataract patients following bilateral implantation of multifocal or…
- Trial name
- MMAQ-IOL (NCT07740590)
- Testing
- Bilateral Bifocal IOL Implantation, Bifocal and EDOF IOL Mix-and-Match Implantation, Bifocal and Monofocal IOL Mix-and-Match Implantation
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Sichuan Academy of Medical Sciences
Cystoid Macular Edema Following Cataract Surgery, Bilateral
Comparison of Topical Ketorolac 0,4% Versus Placebo in Cataract Surgery
The purpose of this study is to compare effects of preoperative and postoperative use of topical ketorolac tromethamine 0.4% versus placebo in uncomplicated cataract surgery.
- Trial name
- NCT01542190
- Testing
- Ketorolac Tromethamine
- Where
- 2 sites in Brazil
- Volunteers
- 80 people
- Sponsor
- University of Campinas, Brazil
Cataract
Assessment of Visual Performance With Virtual Reality After Cataract Surgery
The proposed randomized clinical trial aims to compare visual performance, measured using VR simulations, in cataract patients implanted either with bilateral trifocal IOL or bilateral monofocal IOL with monovision.
- Trial name
- NCT06015334
- Testing
- cataract surgery with implantation of intraocular lens
- Volunteers
- 114 people
- Sponsor
- The University of Hong Kong
Cataract
Accommodation Measurements After Bilateral Implantation of an Aspheric Accommodating Lens and Monofocal Aspheric Lenses
The objective of this study is to demonstrate the correlation of near vision and changes in higher order aberrations following lens extraction and to characterize the defocus curves of Crystalens® AO™ intraocular lens (IOL)…
- Trial name
- NCT01241279
- Testing
- Crystalens AO, SoftPort LI61AO
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract
Combined EDOF / Trifocal
The purpose of this study is to obtain postoperative visual performance data of patients with bilateral implantation of the AT LARA IOL or the AT LARA implanted in the dominant eye and AT LISA tri implanted in the other eye.
- Trial name
- NCT05462067
- Testing
- AT LARA IOL, AT LISA Tri IOL
- Where
- 4 sites in Denmark, Germany and 1 more
- Volunteers
- 72 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract, Bilateral Senile Cataract
Cataract Monitored Anesthesia Care (MAC) Feasibility Pilot Study
The goal of this pilot clinical trial comparing two different sedation approaches for cataract surgery is to assess the feasibility, completeness, and distribution of data in measuring patient satisfaction, the quality of…
- Conditions
- Cataract, Bilateral Senile Cataract, Anesthesia, Patient Satisfaction
- Trial name
- CaTNAPS-1 (NCT06506669)
- Testing
- Oral sedation
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cataract
Clinical Outcomes After Bilateral Implantation of ZEISS AT LISA TRI AND TRI TORIC IOL
The aim of this study is to evaluate the visual function of patients with bilateral implantation of the IOL trifocal ZEISS AT LISA TRI AND TRI TORIC by means of visual acuity tests with and without optical correction, sensitivity…
- Trial name
- NCT02770924
- Testing
- AT LISA TRI TORIC, AT LISA TRI
- Where
- 2 sites in Brazil
- Volunteers
- 20 people
- Sponsor
- Federal University of São Paulo
Cataract Bilateral, Astigmatism Bilateral
Vision and Balance Changes After Bilateral Implantation of Toric IOLs
Cataracts are the major cause of blindness in the world. Cataract surgery, being the most performed surgery in the world today, provide correction by extracting the natural lens from its capsular bag and replaced by an artificial…
- Trial name
- NCT05629078
- Testing
- Toric intraocular lens Zeiss AT TORBI
- Where
- United Kingdom
- Volunteers
- 140 people
- Sponsor
- University of Plymouth
Cataract, Pediatric Cataract
AquaLase Capsule Wash for Pediatric Eyes
To determine whether AquaLase capsule wash reduces posterior capsule opacification (PCO) in pediatric eyes.
- Trial name
- NCT00756327
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Senile Cataract
Safety and Performance of Hydrophobic and Hydrophilic Intraocular Lenses After Bilateral Cataract Surgery
Subjects who had a bilateral age-related cataract surgery with the IOLs AT ELANA 841P and AT LISA tri 839MP will be contacted and invited to attend a postoperative visit more than one year after the surgery
- Trial name
- NCT06192901
- Where
- El Salvador
- Volunteers
- 8 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract
Comparison Between Bilateral Multifocal Intraocular Lenses and Pseudophakic Monovision
More and more patients like to achieve complete spectacle independence after cataract surgery. Two possibilities that are particularly often used today are on the one hand multifocal lenses, and on the other hand the concept of…
- Trial name
- NCT02155348
- Testing
- Bilateral cataract surgery with implantation of multifocal IOLs, Bilateral cataract surgery with monovision, Lentis LS-313
- Where
- Austria
- Volunteers
- 70 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Congenital Cataract
Aphakia Versus Pseudophakia in Children Under 2 Years Undergoing Bilateral Congenital Cataract Surgery
The purpose of this study is to document the safety and efficacy of primary IOL implantation in children below 2 years of age undergoing congenital cataract surgery.
- Trial name
- NCT01297153
- Testing
- Intraocular Lens (Acrysof IOL), No IOL
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Microphthalmos With Congenital Cataracts
Long-term Postoperative Outcomes After Bilateral Congenital Cataract Surgery in Eyes With Microphthalmos
Cataract surgery in infantile eyes, which are microphthalmic, can be even more demanding. In addition, the frequent presence of other ocular and systemic anomalies such as nystagmus, glaucoma, amblyopia, and higher rate of…
- Trial name
- NCT01818037
- Testing
- Cataract surgery
- Where
- India
- Volunteers
- 36 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Cataract, Cataract Surgery
Binocular and Monocular Distance-Corrected Visual Performance and Defocus Characteristics of Clareon Truplus Intraocular Lens (IOL)
This study aims to generate data that characterizes visual outcomes, including the binocular distance-corrected intermediate visual acuity (DCIVA) at 66cm or defocus behavior, of the Clareon TruPlus modified monofocal intraocular…
- Conditions
- Cataract, Cataract Surgery, Cataract Bilateral, Cataract (Post-operative Cataract Surgery Follow-up)
- Trial name
- BMVDI (NCT07589894)
- Testing
- Clareon TruPlus IOL
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Colvard Kandavel Eye Center
Presbyopia, Refractive Errors
Comparison of Premium Monovision and Bilateral Implantation of Trifocal Diffractive Intraocular Lenses
Primary objective of this study is to compare two presbyopia correction surgical techniques, specificaly premium monovision, in which the dominant eye is corrected with an extended depth of field intraocular lens and the…
- Conditions
- Presbyopia, Refractive Errors, Cataract
- Trial name
- NCT05494177
- Testing
- bUDVA, bUIRA, bUNRA, bUICPS, bUNCPS, Contrast sensitivity
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Democritus University of Thrace
Cataract, Cataract (Post-operative Cataract Surgery Follow-up)
Evaluation of Visual Outcomes, Complications, and Neuroadaptation Following Bilateral Implantation of enVista Envy Trifocal Intraocular Lenses
The enVista Envy intraocular lens (IOL) manufactured by Bausch + Lomb is a new multifocal intraocular lens based on diffractive optics.
- Trial name
- NCT07696130
- Testing
- cataract surgery
- Where
- Poland
- Volunteers
- 20 people
- Sponsor
- Pomeranian Medical University Szczecin