Clinical trials: Aviation
Hypoxia, Altitude
Colour Vision Impairment During Acute Hypobaric Hypoxia
This study analyses the impairment of colour vision during hypobaric hypoxia in volunteers of different groups.
- Trial name
- NCT05584813
- Testing
- Hypobaric Hypoxia
- Where
- Germany
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Köln
Oxygen Delivery Systems at Altitude
Aviation Portable Oxygen Delivery System
This study aims to investigate dose based oxygen delivery vs. continuous flow of oxygen during simulated altitude conditions as would be experienced after a loss of pressure during commercial aircraft flight.
- Trial name
- NCT03425409
- Testing
- Integra Pulse Portable- Continuous flow, Integra Pulse Portable- Pneumatic pulsed flow
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Aviation, Heat Stress
Changes in Aviators' Body Core Temperature Measurements at F-35
The many complaints that have been expressed by the US aircrew of the F-35 regarding the heat stress in the cockpit raised an obvious concern that, as a result of such heat levels, the aviators' core body temperature may increase…
- Trial name
- NCT03234270
- Testing
- Core temperature measurements
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Israeli Air Force Aeromedical Center
Noise Exposure
Federal Aviation Administration (FAA) National Sleep Study
This observational study will examine the relationship between aircraft noise exposure in the bedroom and objectively assessed sleep disturbance.
- Trial name
- NSS (NCT05035940)
- Where
- United States
- Volunteers
- 401 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Biospecimen Donation, Environmental Impact
University of Central Florida BEEAST
Since the inception of aerospace travel, NASA has been collecting biospecimens from professional astronauts for research. With the recent growth of civilian aerospace travelers, there is a need for biospecimen banking for…
- Trial name
- NCT06781424
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Low Bone Mineral Density, Muscle Oxygenation
Bone and Muscle Oxygenation in Military Test Pilots
This prospective, single-group interventional pilot study will evaluate the effects of a 12-week resistance and core stabilization exercise program on bone mineral density and resting muscle oxygenation in male military test…
- Trial name
- BMO-MTP (NCT07787143)
- Testing
- Supervised Resistance and Core Stabilization Exercise Program
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Emine Merve Ersever
Back Pain
Light Therapy for the Treatment of Back Pain in Pilots (LLL&Pilots)
Back pain is a common complaint among pilots. Current treatments include physiotherapy and chiropractic manipulations. Low-level laser irradiation (LLLI) in the visible to near-infrared range was shown to reduce neck and low back…
- Trial name
- LLL&Pilots (NCT02665507)
- Testing
- GaAlAs 808nm laser
- Where
- Israel
- Volunteers
- 42 people
- Sponsor
- Hebrew University of Jerusalem
Alertness, Fatigue, Mood, and Performance, Calorie Restriction and Light Intervention
Fatigue in Long-Haul Operations
The purpose of the present study is to test novel countermeasures to reduce fatigue among airline pilots during long-haul flight operations.
- Trial name
- LHops26 (NCT07761611)
- Testing
- Caloric restriction, Light exposure
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- National Aeronautics and Space Administration (NASA)
NASH - Nonalcoholic Steatohepatitis
AVIATION Study: A Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy Study of TERN-201 in Patients With Non-Cirrhotic Non-Alcoholic Steatohepatitis
This is a Phase 1b multi-center, randomized, double-blind, dose-ranging, placebo-controlled, adaptive study to evaluate the safety, pharmacokinetics (PK), pharmacodynamics (PD) of TERN-201 in patients with non-cirrhotic NASH.
- Trial name
- NCT04897594
- Testing
- TERN-201
- Where
- 11 sites in United States
- Volunteers
- 52 people
- Sponsor
- Terns, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Memory Impairment
Age-related Longitudinal Changes in Aviator Performance
Our overall goal has been twofold: 1) to evaluate whether there are significant age-related changes in flight simulator performance near age 60, and 2) to assess whether there is an alternative model that can explain longitudinal…
- Trial name
- NCT01364753
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Stanford University
Hypoxia, Brain
CO2 (Carbon Dioxide) - Cerebral Oxygenation
Several projects in high altitude research in environments with a low oxygen partial pressure (hypobaric hypoxia) leading to hypoxemia showed, that cerebral perfusion and cerebral performance could be improved by adding C02…
- Trial name
- NCT03338907
- Testing
- Oxycarbon (5% CO2+ 95% O2)
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Coronary Artery Disease (CAD), Coronary Artery Calcification
Screening for Coronary Artery Disease USing Primary Evaluation With Coronary CTA in Aviation Medicine (SUSPECT)
SUSPECT is a prospective, single-center, cohort study of 250 military aircrew at the Center for Man in Aviation, Royal Netherlands Air Force.
- Conditions
- Coronary Artery Disease (CAD), Coronary Artery Calcification, Occupational Diseases, Aviator's; Disease
- Trial name
- SUSPECT (NCT05508893)
- Testing
- CT Angiography, Exercise stress test
- Where
- 2 sites in Netherlands
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Pain, Athletic Injuries
Free Fall Acrobatics to Reduce Neck Loads During Parachute Opening Shock: Evaluation of an Intervention.
This study aims to evaluate the use of an aerial human body manoeuvre to reduce the biomechanical load on the neck of a parachutist during the parachute opening, in order to create a basis for future prevention of skydiver neck…
- Conditions
- Pain, Athletic Injuries, Whiplash Injuries, Biomechanical Lesion, Unspecified
- Trial name
- ACROPOSE (NCT02625896)
- Testing
- Intervention
- Where
- Sweden
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Schizophrenia, Persistent Negative Symptoms
Stratifying Psychoses for Personalized REpetitive TMS in Persistent NEgative Symptoms Alleviation
In its 2012's release guideline on therapy for schizophrenia, the EMA joined the FDA to acknowledge primary and persistent negative symptoms (PNS) as an unmet need in the treatment of schizophrenia.
- Conditions
- Schizophrenia, Persistent Negative Symptoms, Progressive Periodic Catatonia, Aviation
- Trial name
- SP-RENESA (NCT06184165)
- Testing
- Personalized rTMS
- Volunteers
- 160 people
- Sponsor
- University Hospital, Strasbourg, France
COPD, Hypoxia
Hypobaric Flight Simulation in COPD Patients
Aim of this study was to evaluate the hypoxic response during hypobaric flight simulation in normal individuals as well as in normocapnic and hypercapnic COPD patients as well as to evaluate the impact of a flight simulation on…
- Conditions
- COPD, Hypoxia, Aviation
- Trial name
- NCT02848391
- Testing
- Environmental
- Where
- Germany
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Krankenhaus Kloster Grafschaft