Clinical trials: Automobile Driving
Visual Performance
Evaluating the Impact of JJVC Senofilcon A - Based Contact Lens With New UV-blocker on Day and Night Driving Performance
This is a bilateral, non-dispensing, randomized, subject masked, four visits, 3-period by 3- treatment crossover study. The objective of this study is to evaluate the effect of JJVC senofilcon A - based contact lens with new…
- Trial name
- NCT03330275
- Testing
- Investigational Contact Lens, Commercial ACUVUE OASYS, Commercial ACUVUE OASYS and Spectacles
- Where
- Australia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Narcolepsy, Excessive Sleepiness
Study Assessing Effects of JZP-110 on Driving Performance in the Treatment of Excessive Sleepiness in Narcolepsy
This trial is a randomized, double-blind, placebo-controlled, crossover study to evaluate the effect of JZP-110 on driving performance in subjects with excessive sleepiness due to narcolepsy.
- Trial name
- NCT02806908
- Testing
- JZP-110
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Jazz Pharmaceuticals
Driving While Intoxicated, Driving Under the Influence
A Web Application to Reduce Heavy Drinking in First-time DWI Offenders
The overall objective of this project is to develop, evaluate, and disseminate a web application for first-time DWI offenders that will provide them with an age-appropriate brief motivational intervention (BMI) to motivate them…
- Conditions
- Driving While Intoxicated, Driving Under the Influence, Heavy Drinking, Alcohol Abstinence
- Trial name
- NCT02071836
- Testing
- Right Turns web application, Treatment as usual
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Behavior Therapy Associates, LLP
Insomnia
Effects of Insomnia on Simulated Driving (MK-0000-183-00)
This is a double-blind, parallel design study in elderly primary insomnia patients and demographically matched controls. The objectives if this study are primarily: 1.
- Trial name
- NCT01209728
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Cataract
Night Driving Pilot
Pilot study to evaluate usability of Mesotest II for assessment of night driving capacity of pseudo-phakic patients implanted with aspheric monofocal posterior chamber IOL *AT.Smart 46LC.
- Trial name
- NCT00876278
- Testing
- *AT.Smart 46LC
- Where
- Germany
- Sponsor
- Carl Zeiss Meditec AG
Healthy
Comparative Effects of Rupatadine 10 mg, Hydroxyzine 50 mg and Placebo on Actual Driving Performance
The primary objective of this study is to measure and compare the acute effects of rupatadine 10 mg, relative to placebo and hydroxyzine 50 mg as an active control on healthy volunteers' performance on a standard over-the-road…
- Trial name
- NCT00162786
- Testing
- Rupatadine, Hydroxyzine
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- J. Uriach and Company
Healthy
A Clinical Study to Assess Next-day Driving Performance Following Administration of ACT-541468 in Middle-aged and Elderly Subjects
A clinical study to assess next-day driving performance following evening administrations of ACT-541468 in middle-aged and elderly subjects
- Trial name
- NCT03892902
- Testing
- ACT-541468, Zopiclone 7.5 mg
- Where
- Netherlands
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Healthy
Study to Assess the Effects of Esketamine on Safety of On-road Driving in Healthy Participants
The purpose of this study is to evaluate the effect of esketamine compared to placebo on driving performance as assessed by the mean difference of standard deviation of lateral position (SDLP) from an on-road driving test in…
- Trial name
- DRiVESaFe (NCT02228239)
- Testing
- Esketamine, Mirtazapine
- Where
- Netherlands
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Depressive Disorder, Major
A Study of Oral Seltorexant as an add-on Medication to an Antidepressant on On-road Driving Performance in Participants With Major Depressive Disorder
The purpose of the study is to evaluate the effect of seltorexant, compared to placebo, as an add-on medication to an antidepressant, on next-day driving performance as assessed by the mean difference of standard deviation of…
- Trial name
- NCT04451187
- Testing
- Seltorexant Dose 1, Seltorexant Dose 2, Zopiclone
- Where
- 2 sites in Belgium, Germany
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Attention Deficit Hyperactivity Disorder
A Study of SPD465 in Young Adult Drivers With Attention-Deficit Hyperactivity Disorder (ADHD) Using Driving Simulators
The purpose of this study is to determine whether SPD465 is safe and effective in the treatment of ADHD in young adult drivers after a duration of 16 hours.
- Trial name
- NCT00458445
- Testing
- SPD465
- Where
- United States
- Sponsor
- Shire
Healthy Participants
Development of Assessment Method for Driving Ability Using Driving Simulator in Healthy Volunteers #3
The purpose of this study is to collect alcohol calibration data for the driving simulator.
- Trial name
- NCT03572985
- Testing
- Road-tracking test, Car-following test, Harsh-braking test
- Where
- Japan
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Taisho Pharmaceutical Co., Ltd.
Choroidal Neovascularization Secondary to Pathologic Myopia
A Study of the Criteria Establishing the Need for Re-treatment With Ranibizumab Upon Relapse in Patients With Visual Impairment Due to Choroidal Neovascularization Secondary to Pathologic Myopia.
The primary objective of the study was to investigate current criteria driving re-treatment in patients affected by Choroidal Neovascularization (CNV) secondary to Pathologic Myopia (PM) and experiencing a relapse of the disease…
- Trial name
- OLIMPIC (NCT02034006)
- Testing
- Ranibizumab
- Where
- 31 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Novartis Pharmaceuticals
Healthy Participants
Development of Assessment Method for Driving Ability Using Driving Simulator in Healthy Volunteers #2
The purpose of this study is to verify the intra-individual difference of the SDLP values in driving simulator.
- Trial name
- NCT03413592
- Testing
- Road-tracking test, Car-following test, Harsh-braking test
- Where
- Japan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Taisho Pharmaceutical Co., Ltd.
Healthy Subjects, Attention Deficit
Identification of Biomarkers to Predict Driver Take-over Control Quality
At level 3 conditionally automated, the vehicle ensures driving and the driver disengages from driving to perform another activity independent of driving (ex: read a book, play on his phone ....).
- Trial name
- ANTIDOTE (NCT04188626)
- Testing
- Driving simulator sessions
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- PSA Automobiles S.A.
Heart Failure, Cardiomyopathies
The Use of the EXCOR Active Driving Unit for Mobilization of Pediatric Patients With Ventricular Assist Device Support
The purpose of this observational study is to evaluate the performance of the Berlin Heart EXCOR Active driving unit while being used with the approved EXCOR ventricular assist device system.
- Conditions
- Heart Failure, Cardiomyopathies, Ventricular Dysfunction, Heart Diseases
- Trial name
- E-Motion (NCT04634708)
- Testing
- No intervention
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Berlin Heart GmbH
Insomnia
Driving Performance After Middle of the Night Administration of 3.5 mg Zolpidem Tartrate Sublingual Tablet
A study in healthy volunteers of the next morning driving performance after middle-of-the-night dosing of 3.5 mg zolpidem tartrate sublingual tablet, a sleep aid.
- Trial name
- NCT01106859
- Testing
- zopiclone, zolpidem tartrate sublingual tablet
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Transcept Pharmaceuticals
Healthy Participants
Development and Validation of a Driving Simulator for Evaluating the Residual Effects of Drugs on Driving Performance - Sensitivity Analysis Using Zopiclone As a Positive Control
The purpose of this study is to confirm of assay sensitivity of Driving Simulator by positive control
- Trial name
- NCT04108351
- Testing
- Road-tracking test, Car-following test, Harsh-braking test
- Where
- 2 sites in Japan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Taisho Pharmaceutical Co., Ltd.
Healthy
A Study of Lasmiditan on Simulated Driving Performance in Healthy Participants
The purpose of this study is to evaluate the effect of lasmiditan on simulated driving performance in healthy participants. Participants are expected to complete each of four study periods, which will last a total of about 10…
- Trial name
- NCT03459612
- Testing
- Lasmiditan, Diphenhydramine
- Where
- 3 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Healthy
Simulated Driving Performance, Daytime Sedation and Cognition in Healthy Volunteers Taking Gralise, Neurontin or Lyrica
Phase 4, double-blind, placebo-controlled, four treatment, four sequence crossover study comparing simulated driving performance, daytime sedation and cognition in healthy volunteers administered therapeutic doses of Gralise®…
- Trial name
- NCT03179345
- Testing
- Gabapentin, Pregabalin
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Depomed
Skin Diseases, Photoaging
Driving Time and Facial Skin Hydration Asymmetry in Florida Drivers
his observational study examines whether time spent driving is associated with differences in skin hydration between the left and right cheeks in female drivers residing in Florida.
- Conditions
- Skin Diseases, Photoaging, Skin Hydration
- Trial name
- DCHA-FL-25-65 (NCT07764809)
- Testing
- BT-Analyze bioimpedance skin hydration measurement
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IAS Skin Care