Clinical trials: Automobile Driving
Peep Titration in Lung Protective Ventilation
Lung Protective Ventilation and Driving Pressure Guided PEEP Titration in CABG Surgery
Our aim in this study is to compare fixed and individualized PEEP (driving pressure guided ) application for intraoperative lung protective ventilation in patients undergoing on-pump CABG surgery.
- Trial name
- NCT07044089
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Walking Cast Right Leg Immobilisation Effects, Aircast Right Leg Immobilisation Effects
The Effects of Lower Right Limb Orthopedic Immobilization on Driving Performance
Abstract Background: Effects of orthopedic immobilizations of the lower right limb on driving performances are unknown. Therefore, clinicians and legislators cannot put forth recommendations for road safety for patients requiring…
- Trial name
- NCT00950729
- Testing
- Driving with running shoes, Plaster cast, Driving with Aircast
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Healthy Volunteers
Sleep Deprivation : Effects on Driving Performance and Central Fatigue
The effects of sleep deprivation (SD) on performance, while contradictory at first glance, are in reality rather clear when exercise duration is considered, i.e. intense/supramaximal versus prolonged exercises.
- Trial name
- PrivSom (NCT01606020)
- Testing
- sleep deprivation, No intervention
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Breast Carcinoma
CAREFOR: Precision Medicine Driving Precision Nutrition for the Treatment of NeoAdjuvant Breast Cancer
The purpose of the study is to determine if a targeted dietary change can enhance the effect of neo-adjuvant chemotherapy
- Trial name
- NCT02827370
- Testing
- Behavioral Dietary Intervention
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Driving Behavior, Driving Under the Influence
Validation of the Drug Impaired Driving Scenario (DIDS) on the CRCDS-miniSim
Subjects will participate in a 4-visit study protocol at the National Advanced Driving Simulator, part of the University of Iowa, in which they will be asked to complete assorted questionnaires, computerized cognitive tasks, and…
- Trial name
- PDID (NCT04970342)
- Testing
- 0.75 mg Alprazolam Capsule, Cannabis (6.18% THC / <0.025% CBD), Cannabis (0%/ THC / 0% CBD)
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Timothy L. Brown
AIDS-Related Opportunistic Infections, Meningo-encephalitis
Driving Reduced AIDS-associated Meningo-encephalitis Mortality
The DREAMM project is investigating whether the DREAMM interventions (1) Health system strengthening, 2) Co-designed education programs tailored to frontline healthcare workers, 3) Implementation of a diagnostic and treatment…
- Conditions
- AIDS-Related Opportunistic Infections, Meningo-encephalitis, Cryptococcal Meningitis, Bacterial Meningitis
- Trial name
- DREAMM (NCT03226379)
- Testing
- DREAMM
- Where
- 5 sites in Cameroon, Malawi and 1 more
- Volunteers
- 495 people
- Sponsor
- St George's, University of London
Parkinson Disease, Multiple Sclerosis
User-friendliness of a Portable Driving Simulator
The use of simulators to retrain driving skills of patients with stroke, Parkinson's disease (PD), or multiple sclerosis (MS) is very limited because of cost, space required, and incidence of simulator sickness in high fidelity…
- Conditions
- Parkinson Disease, Multiple Sclerosis, Stroke
- Trial name
- NCT03969927
- Testing
- Low-Fidelity PDS, High Fidelity Fixed-Base Simulator
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Kansas Medical Center
Cirrhosis
Method of Assessment of Driving Ability in Patients Suffering From Wakefulness Pathologies.
The project will improve scientific knowledge regarding a recent law applying potentially to every french driver. It will give for the first time an indication on the impact of alerting treatments on driving risks.
- Trial name
- AutoSop-Foie (NCT01231828)
- Testing
- L-carnitine, Lactulose
- Where
- France
- Volunteers
- 55 people
- Sponsor
- University Hospital, Caen
Attention Deficit/Hyperactivity Disorder(ADHD)
Effect of Vyvanse on Driving in Young Adults With ADHD
The primary objective of the study is to assess the benefice of Vyvanse on the factors that cause impairments in driving behavior in individuals with ADHD using a driving simulation aimed at examining the factors that cause…
- Trial name
- NCT00801229
- Testing
- Vyvanse
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Massachusetts General Hospital
Visual Performance
Evaluating the Impact of JJVC Senofilcon A - Based Contact Lens With New UV-blocker on Day and Night Driving Performance
This is a bilateral, non-dispensing, randomized, subject masked, four visits, 3-period by 3- treatment crossover study. The objective of this study is to evaluate the effect of JJVC senofilcon A - based contact lens with new…
- Trial name
- NCT03330275
- Testing
- Investigational Contact Lens, Commercial ACUVUE OASYS, Commercial ACUVUE OASYS and Spectacles
- Where
- Australia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
IgG4 Related Disease
Adaptive and Trained Immunity in the Pathogenesis of IgG4-Related Disease
Enquire involvement of trained immunity in the pathogenesis of IgG4RD
- Trial name
- TRIM4 (NCT06844864)
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Sleepiness
Effect of Countermeasures on Nocturnal Driving Performance
Sleep deprivation induces degradation of night-time driving ability via sleepiness. Because of conflicts between physiological needs and social or professional activities, it is necessary to develop affordable countermeasure to…
- Trial name
- KILLSLEEP (NCT01070004)
- Testing
- Real driving situation, Driving simulator
- Where
- 2 sites in France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Autism Spectrum Disorders
A Comparative Study of Driving Performance Among Adolescents With Autism Spectrum Disorder and Neurotypical Adolescents
The primary objective of this study is to compare the number of driving errors made by novice adolescents (0-5 hours of driving instruction) with ASD to those made by neurotypical adolescents during a standardized driving…
- Trial name
- Perf-TSA (NCT07630298)
- Testing
- Assessment of executive functions and attention, Evaluation on a driving simulator, Evaluation on-road
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Hopital La Musse
Acute Respiratory Distress Syndrome
ART-2 Pilot - Driving Pressure Limited Ventilation for Patients With ARDS
This is a multicenter randomized controlled pilot trial to investigate the feasibility of a driving pressure limited mechanical ventilation strategy compared to the ARDS Clinical Network strategy (conventional strategy) in…
- Trial name
- ART2pilot (NCT02365038)
- Testing
- Driving pressure limited ventilation, Conventional ventilation
- Volunteers
- 20 people
- Sponsor
- Hospital do Coracao
Motor Vehicle Crash Injuries
Teenage Passenger Influences on Driving Performance of Teenage Drivers
This study, conducted at the University of Massachusetts at Amherst, will examine how male teenage driving performance varies in the presence or absence of male teenage passengers.
- Trial name
- NCT00716378
- Testing
- Teen Passenger Presence
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Strabismus, Esotropia
Strabismus Surgery and Driving Ability
The strabismus impacts binocular visual acuity and stereoscopy. Thus, driving capacities of patients with strabismus may be reduced.
- Conditions
- Strabismus, Esotropia, Exotropia
- Trial name
- NCT02570555
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Cataract, Presbyopia Correction
Night Driving After Trifocal Versus Monofocal IOL Implantation
This prospective observational cohort study will compare night-driving visual difficulty and visual disturbances after bilateral implantation of an Alcon trifocal intraocular lens or an Alcon monofocal intraocular lens in adults…
- Trial name
- TriIOL (NCT07755189)
- Testing
- AcrySof IQ PanOptix TFNT00 Trifocal Intraocular Lens, Alcon Monofocal Intraocular Lens
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Jin Yang
Cerebral Palsy, Spasticity
Power Wheelchair Joystick Use in Spastic Cerebral Palsy
There are over 750,000 individuals in the U.S. with Cerebral Palsy (CP). Up to 46% of adults with CP report limited mobility in their communities.
- Trial name
- NCT00337688
- Testing
- isometric joystick
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Sleep Deprivation
Chronic Sleep Restriction and Driving
Young subjects and patients with nocturnal respiratory disorders are frequently involved in sleep-related accidents. This study assess the impact of chronic sleep restriction (4 hr of sleep during 5 days) or total sleep…
- Trial name
- PRIVASOM (NCT00560456)
- Testing
- Chronic sleep restriction and driving simulator
- Where
- 2 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Type 1 Diabetes Mellitus, Type 1 Diabetes Mellitus With Hypoglycemia
Glycemic Excursions in Patients With Type 1 Diabetes Mellitus Using Closed-loop Systems
The study aims to compare glycemic excursions during several life situations (such as periods of driving, periods of night sleep, periods of occupation, periods of physical activity, and periods of stress) in patients with type 1…
- Conditions
- Type 1 Diabetes Mellitus, Type 1 Diabetes Mellitus With Hypoglycemia, Drive
- Trial name
- SAFEDRIVE (NCT06382350)
- Testing
- MiniMed 780 G
- Where
- Czechia
- Volunteers
- 120 people
- Sponsor
- University Hospital, Motol