Skin DiseasesDCHA-FL-25-65NCT07764809
Driving Time and Facial Skin Hydration Asymmetry in Florida Drivers
An observational study of Skin Diseases and Photoaging, run by IAS Skin Care at 1 site in United States.
Trial summary
his observational study examines whether time spent driving is associated with differences in skin hydration between the left and right cheeks in female drivers residing in Florida. Read more about this study
- Who is it for?
- Ages 25 to 65 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Skin Diseases, Photoaging, Skin Hydration
- What is being tested?
- BT-Analyze bioimpedance skin hydration measurement
- How many people
- 80 participants
- Where
- 1 siteUnited States
- Study dates
- 5 Oct 2026to 1 Mar 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 25 to 65 years
- Women only
- Healthy volunteers accepted
- Adult, Older adult
Study population: Convenience sample of female drivers aged 25-65 years residing in Florida, recruited from an esthetics practice client base and referral networks in the Orlando metropolitan area.
Who may be able to join
- Female sex, aged 25 to 65 years (inclusive)
- Valid driver's license and active driving for a minimum of 3 years
- Driving frequency of at least 3 days per week on average
- Florida residency for a minimum of 2 years prior to enrollment
- Ability to provide written informed consent in English or Russian
Who cannot join
- Window tinting on the driver-side window of the participant's primary vehicle
- Regular sunscreen application specifically to the left side of the face before driving (more than half of driving occasions in the past month)
- Active skin disease on the face at time of assessment
- Injectable cosmetic procedures (Botox or fillers) in the past 6 months
- Laser resurfacing or chemical peel in the past 3 months
- Inability to refrain from facial cosmetics for at least 2 hours prior to the visit
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
IAS Skin Care
Orlando, Florida, 32835
Olga IAS, M.Sc, 689-249-2677, ias.skincare1@gmail.com
About this study
Official title: Driving Time and Left-Cheek Skin Hydration Asymmetry in Florida Residents: An Observational Study on Cumulative UVA Exposure Through Vehicle Side Windows
his observational study examines whether time spent driving is associated with differences in skin hydration between the left and right cheeks in female drivers residing in Florida. In left-hand-drive vehicles, the driver's left cheek is chronically exposed to ultraviolet A (UVA) radiation through the unshaded side window during every daytime driving episode. A prior study by IAS Skin Care (NCT07564869, n=30) found that the left cheek was less hydrated than the right cheek in 60% of participants, suggesting a possible effect of driving-related UVA exposure on facial skin hydration asymmetry.
Eighty female drivers aged 25-65 years residing in Florida will be enrolled. At a single visit, skin hydration will be measured at three facial zones (left cheek, right cheek, and forehead as a symmetrical control zone) using the BT-Analyze bioimpedance device. Participants will complete a structured questionnaire on driving habits, sun protection practices, and skin history. The primary outcome is the Hydration Asymmetry Index (HAI = right cheek minus left cheek BT-Analyze score). Associations between driving time, cumulative driving exposure, window tinting, sunscreen use, and HAI will be examined using Spearman correlation, Mann-Whitney U tests, and multiple linear regression.
- Conditions
- Skin Diseases, Photoaging, Skin Hydration
- Being tested
- BT-Analyze bioimpedance skin hydration measurement
- Keywords
- skin hydration, UVA exposure, driving, photoaging, bioimpedance, facial asymmetry, Florida, BT-Analyze
- Medical subject headings
- Skin Diseases, Facial Asymmetry
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
BT-Analyze bioimpedance skin hydration measurementOther
Non-invasive skin hydration measurement at three facial zones (right cheek, left cheek, forehead) using the BT-Analyze bioimpedance device. Three measurements per zone. Single visit.
| Study group | Role | What they receive |
|---|---|---|
| Female Florida Drivers | Female drivers aged 25-65 years residing in Florida for at least two years, driving at least 3 days per week, without window tinting on the driver-side window. Receives: Other: BT-Analyze bioimpedance skin hydration measurement |
What is being measured
The primary outcome is the main question the study is designed to answer.
Hydration Asymmetry Index (HAI)
Difference in mean BT-Analyze bioimpedance scores between the right and left cheeks (HAI = right cheek mean minus left cheek mean). A positive value indicates lower hydration on the left cheek relative to the right.
Measured: Single visit (Day 1)
Secondary outcomes (4)
Correlation between cumulative driving exposure and HAI
Spearman correlation between cumulative driving exposure index (years of driving × hours per week) and the Hydration Asymmetry Index.
Measured: Single visit (Day 1)
HAI by window tinting status
Comparison of Hydration Asymmetry Index between participants with tinted versus untinted driver-side windows, assessed by Mann-Whitney U test.
Measured: Single visit (Day 1)
HAI by sunscreen application habit
Comparison of Hydration Asymmetry Index between participants who regularly apply sunscreen to the left side of the face before driving and those who do not, assessed by Mann-Whitney U test.
Measured: Single visit (Day 1)
Forehead hydration as symmetry reference
Forehead BT-Analyze score used as a bilateral symmetry reference zone to confirm that observed cheek asymmetry is directional and not attributable to general hydration differences.
Measured: Single visit (Day 1)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Aug 2026
- Study start5 Oct 2026
- Primary completion1 Mar 2027 (estimated)
- Study completion1 Mar 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Skin DiseasesStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Enrolment
- 80 participants (estimated)
Sponsor and investigators
- Lead sponsor
- IAS Skin Care
- Sponsor type
- Industry (pharma, biotech, devices)
- Responsible party
- Principal investigator, Olga Ias, IAS Skin Care
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07764809
- Sponsor's protocol ID
- IAS-SKIN-2026-002
- Acronym
- DCHA-FL-25-65
- Status last verified
- Oct 2026
- First submitted
- 10 Aug 2026
- Last updated
- 13 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 13 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Driving Time and Left-Cheek Skin Hydration Asymmetry in Florida Residents: An Observational Study on Cumulative UVA Exposure Through Vehicle Side Windows
- ClinicalTrials.gov ID
- NCT07764809
- Acronym / sponsor ID
- DCHA-FL-25-65 / IAS-SKIN-2026-002
- Conditions
- Skin Diseases, Photoaging, Skin Hydration
- Keywords
- skin hydration, UVA exposure, driving, photoaging, bioimpedance, facial asymmetry, Florida, BT-Analyze
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 80 participants (estimated)
- Lead sponsor
- IAS Skin CareIndustry (pharma, biotech, devices)
- Study start
- 5 Oct 2026 (actual)
- Primary completion
- 1 Mar 2027 (estimated)
- Study completion
- 1 Mar 2027 (estimated)
- First posted
- 14 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
his observational study examines whether time spent driving is associated with differences in skin hydration between the left and right cheeks in female drivers residing in Florida. In left-hand-drive vehicles, the driver's left cheek is chronically exposed to ultraviolet A (UVA) radiation through the unshaded side window during every daytime driving episode. A prior study by IAS Skin Care (NCT07564869, n=30) found that the left cheek was less hydrated than the right cheek in 60% of participants, suggesting a possible effect of driving-related UVA exposure on facial skin hydration asymmetry.
Eighty female drivers aged 25-65 years residing in Florida will be enrolled. At a single visit, skin hydration will be measured at three facial zones (left cheek, right cheek, and forehead as a symmetrical control zone) using the BT-Analyze bioimpedance device. Participants will complete a structured questionnaire on driving habits, sun protection practices, and skin history. The primary outcome is the Hydration Asymmetry Index (HAI = right cheek minus left cheek BT-Analyze score). Associations between driving time, cumulative driving exposure, window tinting, sunscreen use, and HAI will be examined using Spearman correlation, Mann-Whitney U tests, and multiple linear regression.
Study design
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Female Florida Drivers | – | Other: BT-Analyze bioimpedance skin hydration measurementFemale drivers aged 25-65 years residing in Florida for at least two years, driving at least 3 days per week, without window tinting on the driver-side window. |
Who may qualify
- Ages
- 25 to 65 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Convenience sample of female drivers aged 25-65 years residing in Florida, recruited from an esthetics practice client base and referral networks in the Orlando metropolitan area.
Key inclusion criteria (5 listed)
- Female sex, aged 25 to 65 years (inclusive)
- Valid driver's license and active driving for a minimum of 3 years
- Driving frequency of at least 3 days per week on average
- Florida residency for a minimum of 2 years prior to enrollment
- Ability to provide written informed consent in English or Russian
Key exclusion criteria (6 listed)
- Window tinting on the driver-side window of the participant's primary vehicle
- Regular sunscreen application specifically to the left side of the face before driving (more than half of driving occasions in the past month)
- Active skin disease on the face at time of assessment
- Injectable cosmetic procedures (Botox or fillers) in the past 6 months
- Laser resurfacing or chemical peel in the past 3 months
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| BT-Analyze bioimpedance skin hydration measurementNon-invasive skin hydration measurement at three facial zones (right cheek, left cheek, forehead) using the BT-Analyze bioimpedance device. Three measurements per zone. Single visit. | Other | Female Florida Drivers |
Primary outcome
Hydration Asymmetry Index (HAI)
Time frame: Single visit (Day 1)
Difference in mean BT-Analyze bioimpedance scores between the right and left cheeks (HAI = right cheek mean minus left cheek mean). A positive value indicates lower hydration on the left cheek relative to the right.
4 secondary outcomes
Correlation between cumulative driving exposure and HAI
Time frame: Single visit (Day 1)
HAI by window tinting status
Time frame: Single visit (Day 1)
HAI by sunscreen application habit
Time frame: Single visit (Day 1)
Forehead hydration as symmetry reference
Time frame: Single visit (Day 1)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Oct 2026.
- Individual participant dataSharing planned: No
Related trials for Skin Diseases
Not yet recruitingPhase 2
Extension Study of Safety and Tolerability of DDY391 in Participants With Moderate to Severe Psoriatic Arthritis (CDDY391A12201-extension)
Moderate to Severe Psoriatic Arthritis
RecruitingPhase 1/2
Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)
Solid Tumor, Non-Small Cell Lung Cancer
RecruitingPhase 1
IL-17 Blockade to Decrease irAEs (REPLAY)
Metastatic Melanoma
Active, not recruiting
Streamlined Geriatric and Oncological Evaluation Based On IC Technology
Breast Cancer, Comorbidities and Coexisting Conditions
RecruitingPhase 2
Gene Signatures to Guide HR+MBC Therapy in a Diverse Cohort
Invasive Mammary Carcinoma, Metastatic Breast Cancer
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Skin Diseases and Photoaging, run by IAS Skin Care at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 13 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Olga IAS, M.Sc (689-249-26-77, ias.skincare1@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Hydration Asymmetry Index (HAI) (time frame: Single visit (Day 1)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Oct 2026.