Clinical trials: Arrhythmia in Children
Heart Rhythm Disorder
Pharmacokinetics of Amiodarone in Children
PK-AMIO study is a population pharmacokinetic study of Amiodarone in children in order to : study the pharmacokinetic parameters (Pop PK) of Amiodarone in children; identify covariates explaining the variability of these…
- Trial name
- PK-AMIO (NCT03842020)
- Testing
- Blood pharmacokinetic samples
- Where
- France
- Volunteers
- 57 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Child Maltreatment, Interpersonal Relations
Beneficial or Fostering Future Struggles (B.F.F.s)? Characterizing the Role of Friends in the Development of 13- to 17-Year-Old Adolescents
The goal of this clinical trial is to investigate how the friendship experiences of maltreated (i.e., abused and/or neglected) and non-maltreated adolescents differentially influence their risk for adverse outcomes.
- Conditions
- Child Maltreatment, Interpersonal Relations, Victimisation, Psychopathology
- Trial name
- BFFs (NCT05893459)
- Testing
- Debrief
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Neonatal Arrhythmias
Management and Clinical Outcome of Neonatal Arrhythmias
assess the Management and clinical outcome of neonatal arrhythmia
- Trial name
- NCT06705621
- Volunteers
- 80 people
- Sponsor
- Assiut University
Wolff-Parkinson-White Syndrome
Physical Activity in Children With Wolff-Parkinson-White Syndrome
The aim of this study was to investigate the level of physical activity and its determinants in children with WPW.
- Trial name
- NCT06349109
- Testing
- Cardiopulmonary exercise test, Atrial-Ventricular Strain Analysis, Arterial Stiffness Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Karamanoğlu Mehmetbey University
Sudden Cardiac Death, Cardiac Arrhythmias
Cardiovascular Pre-participation Screening in Children and Adolescents
Sports participation is strongly encouraged in children and adolescents, but intense training at early ages may reveal hidden heart conditions that increase the risk of sudden cardiac death.
- Trial name
- NCT07862504
- Testing
- Pre-participation clinical evaluation, Diagnostic Test: Resting 12-lead electrocardiogram, Diagnostic Test: Step test (Harvard step test)
- Where
- Brazil
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Down Syndrome, Bradycardia
Down Syndrome Autonomic Nervous System Induction Bradycardia
Children with Down syndrome (DS) often experience dangerously low heart rates on induction of anesthesia for routine procedures and this occurs at 10 times the rate of non-DS patients.
- Trial name
- DANSIB (NCT05120531)
- Testing
- Monitoring patients undergoing surgery to look for association between ANS activity and bradycardia
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism Spectrum Disorder
Biofeedback Intervention in Adolescents With Autism Spectrum Disorder
This study consists of two phases, a cross-sectional and a interventional. The cross-sectional phase will provide more insight into the differences in the autonomic functioning between adolescents with autism spectrum disorder…
- Trial name
- NCT04628715
- Testing
- RSA biofeedback
- Where
- Belgium
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Long QT Syndrome, Catecholaminergic Polymorphic Ventricular Tachycardia Type 1
Evaluation of Exercise Testing and Physical Activity in Children and Adolescents Living With Inherited Arrhythmias
The goal of this observational study is to evaluate exercise testing and daily physical activity in children and adolescents who are diagnosed with an inherited arrhythmia.
- Conditions
- Long QT Syndrome, Catecholaminergic Polymorphic Ventricular Tachycardia Type 1, Catecholaminergic Polymorphic Ventricular Tachycardia Type 2
- Trial name
- ACTIVELY (NCT06661278)
- Testing
- Exercise tolerance test, Physical activity & heart rate monitoring
- Where
- 2 sites in United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Arrhythmia in Children
Pediatric Apple Watch Study
Specific Aim #1 - To determine the accuracy of Apple Watch ECG tracings heart rate in children. Specific Aim #2 - To determine if extended monitoring with the Apple Watch can identify arrhythmia events that were not detected by…
- Trial name
- PAWS (NCT06053372)
- Testing
- Apple Watch
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Stanford University
Supraventricular Arrhythmias, Children
Management of Supraventricular Tachycardias in Children
Background Supraventricular tachycardias (SVTs) are the most common arrhythmic events in children, with an estimated incidence of 13 per 100,000 per year before the age of 18.
- Conditions
- Supraventricular Arrhythmias, Children, Management
- Trial name
- NCT07291544
- Testing
- Management of children with supraventricular tachycardias
- Volunteers
- 1,400 people
- Sponsor
- Paris Cardiovascular Research Center (Inserm U970)
Bradycardia, Arrhythmias
Heart Rate Response to Atropine Doses Less Than 0.1mg IV to Anesthetized Infants
An infants heart rate is very important because it ensures that blood is pumped to all organs in the body. Heart rate may decrease during anesthesia and surgery, and this is why the anesthesiologist will often give a medication…
- Trial name
- NCT01819064
- Testing
- Atropine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- State University of New York at Buffalo
Post Tetralogy of Fallot Repair Arrhythmias and Echocardiographic Changes
Echo, ECG and Holter Findings After Fallot Repair in Children
Aim of my study is to detect echocardiographic, ECG and Holter changes in children who have undergone surgical repair of Tetralogy of Fallot.
- Trial name
- NCT07704346
- Testing
- echocardiography , 12-lead ECG and Holter ECG
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
Tachycardia
Incident and Extent of Pulse Alteration During Local Anesthesia in Children
Incident and extent of pulse alteration during administration of various modes of local anesthesia in children during routine dental treatment.
- Trial name
- NCT02328729
- Testing
- mandibular block with Epinephrine, C-CLAD-IL with Epinephrine, Infiltration with Epinephrine
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose…
- Conditions
- Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension
- Trial name
- POPS or POP02 (NCT04278404)
- Testing
- The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Holter Monitoring in Children Presented With Arrythmia Symptoms
The Use of Holter Monitoring in Children Presented With Arrythmia Symptoms in Sohag University Hospitals
This is a study at Sohag university Hospitals aims to determine overall diagnostic yield of Holter monitoring in children presented with arrythmia symptoms in Sohag university Hospitals, The investigators will include any child…
- Trial name
- Holter-SUH (NCT07760805)
- Testing
- Evaluation of symptoms
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Mariln Nathan Azer
Bundle-Branch Block, Heart Septal Defects, Ventricular
Right Bundle Branch Block After Surgical Closure of Ventricular Septal Defect
The most common congenital heart disease is the ventricular septal defect, and after surgical closure of a such defect, an arrythmia called the right bundle branch block, is very frequent.
- Trial name
- NCT01480908
- Testing
- Echocardiography at rest, Echocardiography during exercise, MRI at rest
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Supraventricular Tachycardia
Sevoflurane and Isoflurane for RF or Cryo Ablation in Children.
In children, radiofrequency catheter ablation (RFCA) or cryoablation are highly effective treatments for supraventricular tachycardia treatment.
- Trial name
- NCT01216501
- Where
- Israel
- Volunteers
- 32 people
- Sponsor
- Schneider Children's Medical Center, Israel
Arrhythmia
Population Pharmacokinetics of Propafenone and Propranolol in Children Patients
The use of propafenone and propranolol in children during clinical treatment was depending mostly on experience. Besides, there was no recommended dose for children in drug instruction.
- Trial name
- NCT05463614
- Testing
- Propafenone and Propranolol
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Shandong University
Circadian Dysrhythmia
Post Discharge Circadian Rhythms Post Adenotonsillectomy
The purpose of this study is to utilize non-invasive, easily measurable biomarkers (heart rate, skin temperature, sleep, and activity) in the post surgical discharge period to identify trends which correlate with improved outcome…
- Trial name
- NCT03217708
- Testing
- Jawbone UP4
- Where
- United States
- Sponsor
- Baylor College of Medicine
Severe Respiratory Syncytial Virus Infection
Retrospective Palivizumab Study in Children With Hemodynamically Significant Congenital Heart Disease
Retrospective medical record review study of specific adverse events in children with congenital heart disease who received palivizumab for prophylaxis of serious respiratory syncytial virus infection and control subjects that…
- Trial name
- NCT01075178
- Where
- 37 sites in Austria, Belgium and 8 more
- Volunteers
- 2,036 people
- Sponsor
- Abbott