Clinical trials: Apraxia
Aphasia, Apraxia of Speech
taVNS for Speech and Language Recovery in Aphasia
The goal of this research study is to evaluate a novel approach to improving speech recovery in those with acquired apraxia of speech.
- Trial name
- NCT07563387
- Testing
- taVNS
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Florida
Childhood Apraxia of Speech
Treating Childhood Apraxia of Speech
The study will test two modifications to speech therapy for 40 school-age children with childhood apraxia of speech to determine how to improve treatment outcomes.
- Trial name
- NCT03238677
- Testing
- Speech Motor Chaining without Biofeedback, Biofeedback, Distributed Practice
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Syracuse University
Speech Sound Disorder, Apraxia of Speech
Efficacy of an Intervention for the Children With Severe Speech Sounds Disorders
Speech sound disorders (SSDs) is one type of communication problems in children. It is a board term describing different difficulties that impact speech intelligibility.
- Conditions
- Speech Sound Disorder, Apraxia of Speech, Developmental Verbal Dyspraxia
- Trial name
- NCT03700151
- Testing
- Treatment for Children with Severe Speech Sound Disorders
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- Chinese University of Hong Kong
Alzheimer Disease, Early Onset, Alzheimer Disease
Early-onset Alzheimer's Disease Phenotypes: Neuropsychology and Neural Networks
This study attempts to identify two types of AD by using clinical and cognitive tasks and brain imaging. The subtypes of AD are separated into a "typical" group (memory loss) and a "variant" group (language, visuospatial, and…
- Conditions
- Alzheimer Disease, Early Onset, Alzheimer Disease, Alzheimer Disease, Late Onset, Dementia, Alzheimer Type
- Trial name
- EOAD-Subtype (NCT03153371)
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Gait Apraxia, Mild Cognitive Impairment
Gait as Predictor of Dementia and Falls. The Gait and Brain Cohort Study
Motor slowing and cognitive slowing are more prevalent as we age. Importantly, the presence of both in an older person increases their risk of having dementia by ten times.
- Conditions
- Gait Apraxia, Mild Cognitive Impairment, Subjective Cognitive Impairment, Cerebral Atrophy
- Trial name
- NCT03020381
- Where
- Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Manuel Montero Odasso
Walking, Cognitive Function
Transcranial and Rapid Magnetic Stimulation for Gait Apraxia Due to Normal Pressure Hydrocephalus and Cerebral Ischemia
The investigator(neurologist) has published a study in International Congress Series, in the 15th International Conference of Biomagnetism Vancouver Proceedings 2006,and Science Direct website, of 15 patients with brain ischemia…
- Trial name
- NCT00494689
- Where
- 2 sites in Singapore
- Volunteers
- 30 people
- Sponsor
- Devathasan Neurology Practice Pte Ltd
Apraxia of Speech
Using tDCS in Speech-based Stroke Rehabilitation
The purpose of this study is to determine whether the effect of treatment for acquired speech impairment can be enhanced by combining effective behavioral treatment with non-invasive brain stimulation.
- Trial name
- NCT03452202
- Testing
- Soterix 1x1 line tDCS low-intensity stimulator
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- NYU Langone Health
Corticobasal Syndrome
Electrical Polarization of the Brain in Corticobasal Syndrome
This study will test whether DC electrical polarization of the brain can temporarily improve hand function in patients with corticobasal syndrome (CBS).
- Trial name
- NCT00273897
- Testing
- Phoresor II
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke, Ideomotor Apraxia
Ideomotor Apraxia and Robotic Gait Rehabilitation Outcomes After Stroke
After a stroke, some people have difficulty planning and carrying out familiar movements. This difficulty is called ideomotor apraxia and cannot be explained by muscle weakness alone.
- Conditions
- Stroke, Ideomotor Apraxia, Hemiplegia
- Trial name
- NCT07881471
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Izmir City Hospital
Cerebral Palsy, Hydrocephalus
Expanded Access Protocol: Umbilical Cord Blood Infusions for Children With Brain Injuries
This protocol is designed to enable access to intravenous infusions of banked umbilical cord blood (CB), that is thawed and not more than minimally manipulated, for children with various brain disorders.
- Conditions
- Cerebral Palsy, Hydrocephalus, Apraxia of Speech, Hypoxia Ischemia, Cerebral
- Trial name
- NCT03327467
- Testing
- Cord Blood Infusion
- Where
- United States
- Sponsor
- Joanne Kurtzberg, MD
Aphasia, Stroke
ReadMap: Reading in Stroke Alexia and Typical Aging
Loss of reading ability due to stroke, called alexia, likely affects over a million Americans at any given time and causes difficulty performing many daily life functions, such as paying bills, using email/text, reading for…
- Conditions
- Aphasia, Stroke, Alexia
- Trial name
- ReadMap (NCT06700005)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Primary Progressive Aphasia, Apraxia of Speech
Treating Primary Progressive Aphasia and Apraxia of Speech Using Non-invasive Brain Stimulation
The purpose of the study is to test whether low level electric stimulation, called transcranial Direct Current Stimulation (tDCS), on the part of the brain (i.e., pre-supplementary motor area and left inferior frontal gyrus)…
- Trial name
- NCT05368350
- Testing
- high-definition transcranial direct current stimulation (HD-tDCS)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- The University of Texas at Dallas
Childhood Apraxia of Speech
Motor-based Intervention for Childhood Apraxia of Speech: DTTC-Connect
Childhood apraxia of speech (CAS) is a complex motor speech disorder that significantly limits a child's ability to communicate in daily activities, with difficulties often persisting into adolescence and adulthood.
- Trial name
- NCT07526246
- Testing
- Dynamic Temporal and Tactile Cueing - Connect (DTTC-Connect)
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- New York University
Cerebral Palsy, Dyspraxia
Immersive Virtual Environments and Wearable Haptic Devices in Rehabilitation of Children With Neuromotor Impairments
The investigators proposed a controlled, single-blind, unicentric, crossover, randomized, clinical trial to test the effects of immersive virtual environments and wearable haptic devices in the rehabilitation of children with…
- Trial name
- SERIOUSGAME (NCT03353623)
- Testing
- Serious Game, Conventional Therapy
- Where
- Italy
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Scuola Superiore di Studi Universitari e di Perfezionamento Sant'Anna
Aphasia, Stroke
Brain Biomarkers of Response to Treatment for Apraxia of Speech
The study will use MRI brain imaging to identify brain changes associated in stroke patients after they receive speech-language treatment for their speech difficulties.
- Trial name
- SPT (NCT02046941)
- Testing
- Speech Production Treatment
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- VA Office of Research and Development
Autism Spectrum Disorder, Apraxia of Speech
Video Assisted Speech Technology to Enhance Motor Planning for Speech
Nearly 3.5 million Americans are diagnosed with Autistic Spectrum Disorder (ASD), a communication disorder that causes skill limitations in the areas of language acquisition, sensory integration, and behavior.
- Trial name
- VAST (NCT04764539)
- Testing
- Video Assisted Speech Therapy (VAST)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- iTherapy, LLC
Stroke, Apraxias
Trial Using CogWatch for Tea Making Training in Stroke Apraxia and Action Disorganisation Syndrome
Apraxia and action disorganization syndrome after stroke can disrupt activities of daily living (ADL). Occupational therapy has been effective in improving ADL performance, however, inclusion of multiple tasks means it is unclear…
- Trial name
- CogWatchTea (NCT04044911)
- Testing
- Task model (CogWatch)
- Volunteers
- 29 people
- Sponsor
- University of Birmingham
Ideomotor Apraxia
Using fMRI to Understand the Roles of Brain Areas for Fine Hand Movements
Ideomotor apraxia, a disorder that affects patients with stroke and a variety of other brain lesions, features disturbed timing, sequence, and spatial organization of skilled movements.
- Trial name
- NCT00063115
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Alzheimer's Disease, Lewy Body's Dementia
Construction-LBD (Constructional Apraxia in Alzheimer's Disease (AD) and Lewy Body's Dementia (LBD))
Alzheimer's disease (AD) and Lewy body's dementia (LBD) are two frequent neurodegenerative pathologies. They differ in their expression, their evolution but share same features which make their diagnosis uneasy.
- Trial name
- NCT01993628
- Testing
- Rey figure test, MRI
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Strasbourg, France
Apraxia, Ideomotor
Effects of Transcranial Direct Current Electrical Stimulation on the Recovery of Ideomotor Apraxia of the Upper Limbs
Limbs apraxia is a motor disorder whose characteristic is the inability or difficulty to perform intentional movements of the limbs (gestures), most frequently involving the upper limbs.
- Trial name
- NCT05259176
- Testing
- transcranial Direct Current Stimulation (tDCS), Behavioural
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Clinica di Riabilitazione Toscana Spa