Clinical trials: Anterior Cervical Spine Surgery
Cervical Vertebrae, Single
The Comparison Between the Stand-alone Cage and the Autologous Iliac Bone Graft/Anterior Plating in the Single-level Surgical Treatment of the Cervical Spine
The use of plate in addition to autologous bone is better then stand alone cage fusion regarding fusion rate and segmental lordosis.
- Conditions
- Cervical Vertebrae, Single, Degenerative Disease
- Trial name
- CAP_2014 (NCT02030899)
- Testing
- Cage fusion, Plate fusion
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Dysphagia
Dysphagia Following Anterior Cervical Spine Surgery; Single Dose Steroid vs Saline (DysDexVSSal)
This prospective, randomized, double blind, controlled study evaluates the effect of a single dose of perioperative IV steroid versus saline on swallowing after anterior cervical spine surgery
- Trial name
- NCT03711474
- Testing
- Dexamethasone, Saline
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Stress
Intermediate Cervical Plexus Block on Stress Response
The aim of the present study is to investigate the effect of Bilateral Ultrasound-Guided intermediate cervical plexus Block combined with general anesthesia on the stress and inflammatory response in patients undergoing anterior…
- Trial name
- NCT06064214
- Testing
- u/s guided intermediate cervical plexus block
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cervical Disc Disease, Radiculopathy, Cervical
Physiotherapy After Anterior Cervical Spine Surgery
Background: Patients suffering residual disability after anterior decompression and fusion (ACDF) surgery for cervical disc disease may be prescribed physical activity (PPA) or neck-specific exercises (NSE).
- Trial name
- NCT03036007
- Testing
- Prescribed Physical Activity, Exercises with Internet support
- Where
- Sweden
- Volunteers
- 39 people
- Sponsor
- Linkoeping University
Intubation, Intratracheal, Pain, Postoperative
Tracheal Tube Cuff Shape and Pressure
This is a randomized controlled trial focusing on the effect of different tracheal tube cuff shape; the tapered-shaped tracheal tube cuff versus the cylindrical-shaped tracheal cuff in anterior cervical spine surgery.
- Conditions
- Intubation, Intratracheal, Pain, Postoperative, Dysphonia
- Trial name
- NCT04591769
- Testing
- Different tracheal tube cuff design
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Pressure Injury, Dysphonia
Initial Increase in Cuff Pressure in Anterior Cervical Spinal Surgery
When the retractor blades oped and is positioned to provide the surgical access in the anterior cervical spine surgery, it cause the trachea to deviate laterally and pose pressure on the tissue between the retractor and the…
- Conditions
- Pressure Injury, Dysphonia, Dysphagia
- Trial name
- NCT03240042
- Testing
- nasotracheal intubation, orotracheal intubation
- Where
- Taiwan
- Volunteers
- 118 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Spine Fusion, Spine Surgery
Fusion Status After ACDF
Pseudarthrosis, a failure of bony fusion, is one of the most common causes of revision surgery following anterior cervical discectomy and fusion (ACDF).
- Trial name
- NCT05986006
- Testing
- Anterior Cervical Disc Fusion (ACDF) Surgery w/ machined bone allograft, Anterior Cervical Disc Fusion (ACDF) Surgery w/ Iliac Crest Bone Graft
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Degenerative Disc Disease, Trauma (Including Fractures)
BIO4 Clinical Case Study: Cervical Spine
The goal of this study is to investigate the efficacy of BIO4 bone matrix in patients undergoing 1 or 2-level Anterior Cervical Discectomy and Fusion (ACDF) spine surgery.
- Conditions
- Degenerative Disc Disease, Trauma (Including Fractures), Spondylolisthesis
- Trial name
- NCT03077204
- Testing
- 1 or 2-Level ACDF utilizing BIO4 with Bio AVS Cervical Allograft (with graft window)., Aviator Anterior Cervical Plating System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Seton Healthcare Family
Hypopharyngeal Pressure Changes Between Before and After Swallowing Rehabiliation
Enhancing Early Swallowing Recovery in Older Dysphagic Patients Afetr Anterior Cervical Spine Surgery
The early swallowing rehabilitation program in older patients receiving elective surgery is regarded to enhance the recovery pf swallowing ability.
- Trial name
- NCT05494515
- Testing
- the early swallowing rehabilitation program
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Wound Heal
Platysma Incision Cosmesis
The anterior cervical fusion and decompression (ACDF) surgery provides direct access to symptomatic areas of the cervical spine.
- Trial name
- NCT03338608
- Testing
- Anterior Cervical Decompression and Fusion, Vertical Platysma Incision, Transverse Platysma Incision
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Boston Medical Center
Dysphagia After Anterior Cervical Decompression and Fusion of the Spine, Dysphonia
Dysphagia and Dysphonia in Anterior Cervical Spinal Surgery
Introduction: The anterior cervical approach is used to treat a variety of spinal disorders; among these, the Smith-Robinson approach is the most commonly used, as it allows access to discs, bony structures, and anterior lesions…
- Conditions
- Dysphagia After Anterior Cervical Decompression and Fusion of the Spine, Dysphonia, Anterior Cervical Spinal Surgery
- Trial name
- NCT07713693
- Testing
- Fiberoptic Endoscopic Evaluation of Swallowing, 30-item questionnaire designed to assess the impact of speech dysfunction on the patient's daily life, EAT-10 questionnaire
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- Instituto Nacional de Rehabilitacion
Anterior Cervical Spine Surgery
ACSS Approach on Dysphagia
Anterior cervical spine surgery (ACSS) is a procedure for the treatment of several neck problems. Even though the procedure is overall safe and effective, there are possible complications after surgery, which include problems…
- Trial name
- NCT07533864
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Hamilton Health Sciences Corporation
Spinal Fusion, Cervical Spine Degenerative Disease
Early Postoperative Home Exercise Program After Cervical Spine Surgery
The overall objective of this two-group randomized controlled trial is to gather preliminary evidence on the efficacy and safety of early postoperative exercise for improving disability, pain, and general physical health in…
- Trial name
- NCT02720172
- Testing
- Early Home Exercise Program, Usual Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vanderbilt University Medical Center
Patients Receiving Anterior Cervical Spine Surgery
Swallowing Motor Function After Cervical Spine Surgery With Anterior Approach
Dysphagia is a well-known complication following anterior cervical spine surgery. However, which muscle at oropharyngeal region weakness and the recovery course of these patients are still unknown.
- Trial name
- NCT03891940
- Testing
- patients recieving anterior cervical spine surgery
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Dysphagia, GERD
Whether Proton Pump Inhibitors, Administered Prior to or After Surgery, Can Reduce the Incidence and/or Severity of Difficulty Swallowing Foods and/or Liquids,Following Anterior Cervical Surgery
The researchers wish to investigate whether proton pump inhibitors, administered prior to or after surgery, can reduce the incidence and/or severity of difficulty swallowing foods and/or liquids,following anterior cervical…
- Conditions
- Dysphagia, GERD, Degenerative Joint Disease
- Trial name
- NCT03488147
- Testing
- Esomeprazole
- Where
- 2 sites in United States
- Sponsor
- Icahn School of Medicine at Mount Sinai
Traumatic Cervical Spine Instability
Anterior Only Surgery for Management of Traumatic Subaxial Cervical Spine Instability
Classic management of cervical spine sublaxation and dislocation is combined anterior and posterior approach. Unfortunately there are disadvantages for this approach like: increasing morbidity related to each approach, increasing…
- Trial name
- NCT03149497
- Testing
- anterior approach only in cervical spine trauma
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- arsany botros saleh
Radiculopathy, Cervical, Myelopathy Cervical
Cervical Arthroplasty Cost Effectiveness Study (CACES)
To date, no consensus exists on which anterior surgical technique is more cost-effective to treat cervical degenerative disc disease (CDDD).
- Conditions
- Radiculopathy, Cervical, Myelopathy Cervical, Myelopathy, Compressive, Radiculopathy, Cervical Region
- Trial name
- CACES (NCT04623593)
- Testing
- ACDF, ACDA
- Where
- Netherlands
- Volunteers
- 198 people
- Sponsor
- Valérie Schuermans
Cervical Spine Degeneration
Analgesic Effectiveness of Nefopam in Patients Undergoing Anterior Cervical Spine Surgery
Nefopam is a benzoxazocine derivative which is non-opioid and non NSAIDs. The previous studies showed that nefopam can inhibit reuptake of serotonin, norepinephrine and dopamine.
- Trial name
- NCT03955705
- Testing
- Nefopam 20 mg/ml, Normal saline
- Where
- Thailand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Cervical Spine Disc Disease, Surgery
ACDF Comparison Trial
This research protocol seeks to compare radiological and clinical outcomes of cervical spine disease patients following standard-of-care anterior cervical discectomy and fusion (ACDF) using allograft fusion versus Cohere porous…
- Conditions
- Cervical Spine Disc Disease, Surgery, Fusion of Spine, Degenerative Disc Disease
- Trial name
- NCT03187171
- Testing
- Allograft Fusion, Cohere PEEK Fusion Group
- Sponsor
- Duke University
Cervical Disc Degeneration
Real World Data Collection and Analysis on the Anterior Cervical Spine Surgery
This observational study aims to evaluate the efficacy and safety of anterior cervical spine surgery in patients with cervical degenerative disc disease
- Trial name
- ACCSS (NCT05602714)
- Testing
- Collection Data
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Beijing Tiantan Hospital