Clinical trials: Angiography
Multiple Pulmonary Emboli
Efficacy of Low (30ml) Versus Full Dose (100ml) Contrast CT Pulmonary Angiography in Detecting Emboli
With the improvement in CT scanners and injectors, diagnostic chest CT can now be performed in less than 10 seconds. It was hypothesized that diagnostic CT pulmonary angiograms could be done with less than the usual 80-120 ml of…
- Trial name
- NCT01935141
- Testing
- Low-Dose IV Contrast, Siemens Sensation 64-MDCT scanner., Visipaque 320 non-ionic isoosmolar contrast agent
- Where
- United States
- Sponsor
- VA Greater Los Angeles Healthcare System
Contrast-induced Nephropathy, Coronary Angiography
Using Preprocedural Urine NMR(Nuclear Magnetic Resonance) -Based Metabolomics Analysis
The use of coronary intervention has increased over the last decade. Contrast induced nephropathy (CIN) that develops as a result of procedures using intravenous or intra arterial contrast enhancement, or other diagnostic…
- Trial name
- NCT03731962
- Testing
- Coronary Angiography
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Coronary Microvascular Dysfunction, Heart Failure With Preserved Ejection Fraction (HFpEF)
Women's Ischemia Syndrome Evaluation (WISE) Pre-HFpEF
The purpose of this study is to examine small vessel disease (a condition in which the small arteries in the heart become narrowed).
- Trial name
- NCT03876223
- Where
- 2 sites in United States
- Volunteers
- 180 people
- Sponsor
- Cedars-Sinai Medical Center
Peripheral Arterial Disease
BIO REsponse Adapted Combination Therapy Pilot Study
Both drug-coated balloon and stents have been used for a number of years to treat subjects with Peripheral Artery Disease (PAD) and are recognized as very good treatment methods.
- Trial name
- NCT03547986
- Testing
- Duplex Ultrasound (DUS), IVUS with Intraarterial pressure measurement (IAP) if needed
- Where
- 15 sites in Australia, Austria and 4 more
- Volunteers
- 150 people
- Sponsor
- Biotronik AG
Lower Gastrointestinal Bleeding
MSCT Angiography in Bleeding
Lower gastrointestinal bleeding occurs distal to the ligament of treitz and may involve the small bowel, colon and rectum . Active lower gastrointestinal bleeding is a common, potentially life threatening medical presentation…
- Trial name
- NCT03464513
- Testing
- Multislice CT Angiography
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Assiut University
Coronary Artery Disease
Silicon-based Photon Counting Computed Tomography for Advanced Cardiac Imaging
Computed tomography (CT) is a key imaging modality, with rapidly increasing use in cardiovascular diagnostics. Coronary CT angiography (CCTA) provides high-resolution, non-invasive assessment of coronary anatomy and is now…
- Trial name
- SILIC-HEART (NCT07411196)
- Testing
- Photon-counting computed tomography
- Volunteers
- 1,000 people
- Sponsor
- Ronny R Buechel, MD
Acute Kidney Injury
Tailored Hydration Based on Bioimpedance Analysis for Prevention of Contrast Induced Acute Kidney Injury
The aim of this study was to evaluate, in patients with "normal fluid status" assessed by the bio-impedance analysis, whether two different protocol of IV isotonic saline infusion are associated with different volume expansion…
- Trial name
- Hydra2 (NCT04215042)
- Testing
- sodium chloride infusion
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Ospedale Misericordia e Dolce
Microvascular Coronary Artery Disease, STEMI
Clinical Trial for Evaluating the Effectiveness and Safety of Online caIMR in STEMI Patients
Despite the success of restoration of epicardial blood flow by the primary percutaneous coronary intervention (PPCI), approximately a half of patients with ST-segment elevation myocardial infarction (STEMI) have failed myocardial…
- Trial name
- FlashIV (NCT06118450)
- Testing
- Non-intervention
- Where
- 8 sites in China
- Volunteers
- 335 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Coronary Artery Disease
One-Dimensional Mathematical Model-Based Automated Assessment of Fractional Flow Reserve
This study evaluates the diagnostic efficiency of an automated method of noninvasive assessment of the fractional reserve of coronary blood flow.
- Trial name
- NCT03797118
- Testing
- FFR
- Where
- Russia
- Volunteers
- 31 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Pulmonary Embolism, Radiation Exposure
MR Pulmonary Angiography to Replace CT Pulmonary Angiography for Patients With a Suspicion of a Pulmonary Embolism
Rational: The first choice of imaging modality for patients with a suspicion of pulmonary embolism is CT pulmonary angiography (CTPA).
- Trial name
- MIRACLE (NCT05879380)
- Testing
- MRPA, CPTA
- Volunteers
- 272 people
- Sponsor
- Noordwest Ziekenhuisgroep
Ventricular Tachycardia, Ventricular Fibrillation
Registry of Malignant Arrhythmias and Sudden Cardiac Death - Influence of Diagnostics and Interventions
The "Registry of Malignant Arrhythmias and Sudden Cardiac Death - Influence of Diagnostics and Interventions (RACE-IT)" represents a mono-centric registry of patients being hospitalized suffering from malignant arrythmias…
- Conditions
- Ventricular Tachycardia, Ventricular Fibrillation, Sudden Cardiac Death, Coronary Angiography
- Trial name
- RACE-IT (NCT02982473)
- Where
- Germany
- Volunteers
- 3,200 people
- Sponsor
- Universitätsmedizin Mannheim
Glaucoma
Phosphodiesterase Inhibitors in Glaucoma Study (PhiGS)
It is commonly known that high eye pressure is associated with glaucoma. However, there is also a theory that poor circulation to the eye is a contributing factor.
- Trial name
- PhiGS (NCT04052269)
- Testing
- Sildenafil 100mg
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Imperial College London
Coronary Artery Disease
Dual-antiplatelet Therapy Strategies for Elective PCI in a Real-world Setting
To assess the safety and efficacy of in-laboratory clopidogrel loading dose administration before ad-hoc PCI versus clopidogrel preloading treatment in patients planned for diagnostic angiography with optional ad-hoc PCI.
- Trial name
- DAPT-FOR-REAL (NCT05559918)
- Where
- 2 sites in Netherlands
- Volunteers
- 1,462 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Acute Renal Failure
Intravenous High Dose NAC and Sodium Bicarbonate for the Prevention of Contrast-induced Acute Injury
Contrast-induced acute kidney injury is a common cause of acquired in-hospital renal insufficiency and is associated with prolonged hospitalization and unfavorable early and late outcomes.
- Trial name
- NCT01612013
- Testing
- Sodium bicarbonate plus saline, Intravenous NAC plus saline, NAC plus sodium bicarbonate plus saline
- Where
- Brazil
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Diabetic Retinopathy, Periodontitis
Periodontitis Severity in Patients With Diabetic Retinopathy
The aim of this observational study is to investigate the relationship between periodontal disease severity and retinal layer thickness in patients diagnosed with diabetic retinopathy (DR), using optical coherence tomography…
- Trial name
- NCT07137013
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Thoracoabdominal Aortic Aneurysm
Automated Carbon Dioxide Angiography in Fenestrated/Branched Endovascular Abdominal Aortic Aneurysm Repair
Carbon Dioxide (CO2)-based angiography is a digital subtraction angiography (DSA), where CO2 is used as an intra-arterial contrast agent.
- Trial name
- NCT06103942
- Testing
- CO2 angiography
- Volunteers
- 30 people
- Sponsor
- Uppsala University
Pulmonary Embolism
Comparison of 3 Diagnostic Strategies of PE: Planar V/Q Scan, CTPA, and V/Q SPECT.
Pulmonary embolism (PE) remains a diagnostic challenge. False negative testing exposes patient to the risk of potentially fatal recurrence.
- Trial name
- SPECTACULAR (NCT02983760)
- Testing
- Planar V/Q-based strategy, CTPA-based strategy, V/Q SPECT-based strategy
- Where
- 11 sites in Canada, France and 1 more
- Volunteers
- 611 people
- Sponsor
- University Hospital, Brest
Alzheimer's Disease, Mild Cognitive Impairment
Retinal Imaging in Neurodegenerative Disease
This study aims to develop and evaluate biomarkers using non-invasive optical coherence tomography (OCT) and OCT angiography (OCTA) as well as ultra-widefield (UWF) fundus photography to assess the structure and function of the…
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Parkinson's Disease, Multiple Sclerosis
- Trial name
- NCT03233646
- Testing
- Retinal and Choroidal Imaging
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Radial Artery Spasm, Radial Artery Access
The Effect of Using Virtual Reality Glasses on Anxiety-related Radial Vasospasm in Patients Undergoing Transradial Coronary Angiography
Compared to transfemoral access, transradial access is a safe and effective method for coronary interventions, associated with lower rates of vascular complications, including major bleeding.
- Conditions
- Radial Artery Spasm, Radial Artery Access, Virtual Reality
- Trial name
- NCT06726031
- Testing
- wearing VR glass
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mersin University
Gastric Varices
Angiography for Evaluation of the Feeder Vessel in EUS-guided Coils and Cyanoacrylate Therapy for Gastric Varices
INTRODUCTION: Bleeding from gastric varices (GV) is associated with a high mortality rate. Injection of cyanoacrylate (CYA) using standard gastroscope has demonstrated to achieve higher hemostasis and lower rebleeding rates…
- Trial name
- NCT03277937
- Testing
- angiography in EUS-injection of coils + CYA
- Where
- Ecuador
- Volunteers
- 30 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
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