Clinical trials: Aneurysm Cerebral
Subarachnoid Aneurysm Hemorrhage
Early Motor-Cognitive Integrative Training on Cognitive and Motor Performance in Patients With Aneurysmal Subarachnoid Hemorrhage
Despite its lower incidence rate within the stroke population and tendency to affect younger individuals, SAH carries the highest risk of PSCI.
- Trial name
- NCT07588997
- Testing
- early motor-cognitive integrated training (e-MCIT), Early mobilization
- Where
- Taiwan
- Volunteers
- 18 people
- Sponsor
- National Taiwan University Hospital
Migraine Without Aura
Effect of PACAP38/VIP on Migraineurs Measured by Magnetic Resonance
The purpose of this study is to examine and compare the effect of pituitary adenylate cyclase-activating polypeptide-38 (PACAP38) and vasoactive intestinal polypeptide (VIP) on intracranial arteries and neuronal activity in…
- Trial name
- NCT01471990
- Testing
- Pituitary Adenylate Cyclase-Activating Polypeptide-38, Vasoactive Intestinal Peptide
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Endocarditis, Bacterial, Aneurysm, Intracranial Mycotic
Neurological Complication of Infective Endocarditis: A Prospective Multi-site Cohort Study
The main objective of this study is to better estimate the rate of infectious intracranial aneurysms (IIA) in proved infective endocarditis (IE).
- Trial name
- NCT05152225
- Testing
- Brain MRI, digital subtraction angiography (DSA)
- Volunteers
- 200 people
- Sponsor
- the Jeunes en Neuroradiologie Interventionnelle (JENI) research group
Intracranial Aneurysm
SEAL™IT: Saccular Endovascular Aneurysm Lattice System Interventional Pivotal Trial
To establish the safety and effectiveness of the SEAL™ Saccular Endovascular Aneurysm Lattice system for the treatment of saccular intracranial aneurysms.
- Trial name
- SEAL™IT (NCT05831202)
- Testing
- The SEAL™ Saccular Endovascular Aneurysm Lattice System
- Where
- 6 sites in United States
- Volunteers
- 279 people
- Sponsor
- Galaxy Therapeutics INC
Unruptured Cerebral Aneurysm, Treatment Strategy
New Therapeutic System of Unruptured Intracranial Aneurysms Based on Big Data From Chinese Population
This is a prospective, multicenter, observational study, aiming at comparing the Safety and effectiveness among the different surgical treatment of unruptured intracranial aneurysms in China, so as to improve the diagnosis and…
- Trial name
- NATIONAL-1 (NCT03153865)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Changhai Hospital
Aneurysm, Ruptured, Subarachnoid Hemorrhage
Clinical Efficacy of In-situ Thrombolysis in Case of Intraventricular Haemorraghia by Aneurysm Rupture
The purpose of this study is to determine the impact of in situ fibrinolysis on the mortality at 30 days in case of subarachnoid hemorrhage.
- Trial name
- NCT00823485
- Testing
- fibrinolysis in situ, drainage
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Ischemic Stroke, Patent Foramen Ovale
Patent Foramen Ovale Closure or Anticoagulants Versus Antiplatelet Therapy to Prevent Stroke Recurrence
A patent foramen ovale (PFO) is found more frequently in patients with an ischemic stroke than in control subjects. Therapeutic options to prevent stroke recurrence include antiplatelet drugs, oral anticoagulants, and…
- Conditions
- Ischemic Stroke, Patent Foramen Ovale, Atrial Septal Aneurysm, Migraine
- Trial name
- CLOSE (NCT00562289)
- Testing
- aspirin, Antivitamins K or rivaroxaban or dabigatran or apixaban, Devices for PFO closure
- Where
- France
- Volunteers
- 664 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cerebral Arterial Disease, Cerebral Aneurysm
Esmolol Infusion in Patients Undergoing Craniotomy
Anesthesia techniques that minimize anesthetic requirements and their effects may be beneficial. Esmolol, a short acting hyperselective β-adrenergic blocker is effective in blunting adrenergic response to several perioperative…
- Trial name
- NCT02455440
- Testing
- Esmolol, Propofol and sevoflurane
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- George Papanicolaou Hospital
Intracranial Aneurysm
Pilot Study of the Contour Neurovascular SystemTM
Prospective, single arm, multi centre study to evaluate the safety and performance of the Contour Neurovascular SystemTM in the treatment of intracranial aneurysm (IA)
- Trial name
- NCT02784431
- Testing
- Contour Neurovascular System placement
- Volunteers
- 20 people
- Sponsor
- Cerus Endovascular, Inc.
Unruptured Cerebral Aneurysm, Artificial Intelligence (AI)
AI Models for Cerebral Aneurysms Segmentation, Detection and Stability Prediction
Aneurysmal subarachnoid hemorrhage (SAH) is one of the critical diseases that severely threaten human health, with a clinical mortality rate reaching as high as 30%.
- Conditions
- Unruptured Cerebral Aneurysm, Artificial Intelligence (AI), Subarachnoid Hemorrhage, Aneurysmal, Magnetic Resonance Angiography
- Trial name
- AI-CARE (NCT06766422)
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Intracranial Aneurysm
Pivotal Study of the Silk Vista Baby Flow Diverters in the Treatment of Unruptured Intracranial Aneurysms (PIONEER)
The PIONEER Study is a pivotal, multi-center, prospective, single-arm study designed to evaluate the safety and efficacy of the Silk Vista Baby (SVB) Flow Diverter for the treatment of unruptured aneurysms.
- Trial name
- PIONEER (NCT07225075)
- Testing
- Silk Vista Baby (SVB) Flow Diverter
- Where
- 6 sites in United States, Canada
- Volunteers
- 250 people
- Sponsor
- Balt USA
Subarachnoid Hemorrhage, Aneurysmal, Intracranial Aneurysm
Predictors of Rupture Risk of Intracranial Aneurysms
Patients admitted to Haukeland University Hospital with either UIA or aSAH underwent a measurement of bioelectrical impedance and body mass composition using InBody 10. Lipids and lipoproteins were collected from plasma.
- Trial name
- RAPID (NCT04613427)
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University of Bergen
Subarachnoid Hemorrhage, Cerebral Vasospasm
Sildenafil for Prevention of Cerebral Vasospasm
A Randomized Clinical Trial with security and dose testing of Sildenafil Citrate in patients with subarachnoid hemorrhage due to a rupture of a cerebral aneurism for prevention of cerebral vasospasm.
- Conditions
- Subarachnoid Hemorrhage, Cerebral Vasospasm, Rupture of Intracranial Aneurysm
- Trial name
- SIPCEVA (NCT01091870)
- Testing
- Sildenafil Citrate, 25 mg, 3 times a day., Sildenafil Citrate 50 mg, 3 times a day
- Where
- Brazil
- Sponsor
- Hospital de Clinicas de Porto Alegre
Intracranial Saccular Aneurysm, Either Rupture or Unruptured, Wide Neck Aneurysm
Solitaire Aneurysm Remodeling Registry
The objective of the registry is to evaluate the effectiveness and performance of the Solitaire Neurovascular Remodeling Device when used with embolic coils in the treatment of intracranial aneurysms.
- Trial name
- NCT04905303
- Where
- France
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Aneurysm, Intracranial
US IDE Study of the Contour NEurovasCular System™ for IntraCranial Aneurysm Repair
The purpose of this trial is to gather data on the safety and effectiveness of the Contour /Contour 021 System in the treatment of wide-necked bifurcated saccular, intracranial aneurysms for submission to FDA in support of a…
- Trial name
- NECC (NCT04852783)
- Testing
- Contour Neurovascular System
- Where
- 20 sites in United States
- Volunteers
- 250 people
- Sponsor
- Cerus Endovascular, Inc.
Aneurysm Cerebral
Interest of a Simulated Procedure Performed on a Printed Model in the Endovascular Treatment of Carotid-sylvian Aneurysms
It is now considered that 1% to 2% of the French population has an intracranial aneurysm. The major risk of this malformation is essentially the rupture which will lead in 10% of cases to death immediately, in 30% to 50% death…
- Trial name
- Anev3D (NCT05419661)
- Testing
- Operational Pre-Planning
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Brest
Carotid Artery Stenosis, Abdominal Aortic Aneurysm
Prevalence of Carotid Artery Stenosis and Abdominal Aortic Aneurysms in Brussels: a Population-based Screening Study.
Both abdominal aortic aneurysm (AAA) and carotid artery stenosis (CAS) are frequent clinical entities, with major morbidity and mortality.
- Conditions
- Carotid Artery Stenosis, Abdominal Aortic Aneurysm, Epidemiology
- Trial name
- NCT04098523
- Testing
- Duplex ultrasound
- Where
- Belgium
- Volunteers
- 3,286 people, healthy volunteers welcome
- Sponsor
- Erik Debing
Cerebral Aneurysm
A Medical Device to Treat Brain Aneurysms
An aneurysm is a bulge in a blood vessel caused by a weakness in the blood vessel wall, usually where it branches. As blood passes through the weakened blood vessel, the blood pressure causes a small area to bulge outwards like a…
- Trial name
- NCT04963933
- Testing
- Nautilus endovascular device
- Where
- 2 sites in Bulgaria, Latvia
- Volunteers
- 30 people
- Sponsor
- EndoStream Medical
Intracranial Aneurysm
Perioperative Neuroprotection of Stellate Ganglion Block
To investigate whether stellate ganglion block is helpful to brain protection during cranial aneurysm surgery
- Trial name
- NCT02275247
- Testing
- Stellate Ganglion Block
- Where
- China
- Volunteers
- 40 people
- Sponsor
- General Hospital of Ningxia Medical University
Intracranial Aneurysms
MAPS Trial: Matrix And Platinum Science
Primary Objectives: To establish Target Aneurysm Recurrence (TAR) rates for Matrix 2® and GDC® Coils used for the treatment of intracranial saccular aneurysms.
- Trial name
- MAPS (NCT00396981)
- Testing
- Matrix 2® coils for endovascular aneurysm occlusion, GDC® coils for endovascular aneurysm occlusion
- Where
- 43 sites in United States, Australia and 9 more
- Volunteers
- 626 people
- Sponsor
- Stryker Neurovascular