Clinical trials: Anesthesia Awareness
Fraily, Abdominal Surgery
Awareness Neuraxial Versus General Anesthesia in Frail Patients Undergoing Laparoscopic or Robotic Abdominopelvic Surgery.
This is a bicentric, prospective, non-pharmacological, randomized study designed to compare the efficacy and safety of awake neuraxial anesthesia with sedation versus general anesthesia in frail patients undergoing elective major…
- Conditions
- Fraily, Abdominal Surgery, Postoperative Cognitive Dysfunction (POCD)
- Trial name
- SAFE-AWARENESS (NCT07486336)
- Testing
- Neuraxial anesthesia, General Anesthesia, avoidance of GABAergic-drugs strategy
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Ente Ospedaliero Ospedali Galliera
Intraoperative Awareness, Anesthesia, General
Subconscious Effects of Intraoperative Speech: Health Professionals' Perceptions
This observational, questionnaire-based study aims to evaluate health professionals' perceptions regarding the potential subconscious effects of intraoperative conversations on patients.
- Conditions
- Intraoperative Awareness, Anesthesia, General, Consciousness
- Trial name
- NCT07396727
- Testing
- Questionnaire / Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Consciousness, Level Depressed, Intraoperative Awareness
Awareness During Blended Anaesthesia
the aim of this study was to estimate the relations between Bispectral Index values and explicit or implicit memory or dreams during two different minimal alveolar concentration (MAC) of sevoflurane in patients undergoing blended…
- Trial name
- NCT01800578
- Testing
- monitor for depth of hypnosis
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Germano De Cosmo
Anesthesia Awareness
Heart Rate Variability to Quantify General Anesthesia Depth
The shortage of anesthetic agents can lead to intraoperative awareness while overdosing can trigger severe intra and postoperative problems.
- Trial name
- NCT04788732
- Testing
- ECG and EEG monitoring
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo
Breast Cancer, Quality of Life
Effect of Chan-Chuang Qigong With Breathing Meditation on Quality of Life in Patients With Breast Cancer
The aim of this study was to evaluate the effect of the 15 weeks Chan-Chuang qigong program with breathing meditation on quality of life and interoceptive awareness in patients with breast cancer during chemotherapy.
- Conditions
- Breast Cancer, Quality of Life, Intraoperative Awareness
- Trial name
- NCT05385146
- Testing
- qigong
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Ching-I Chang
Intraoperative Awareness
Incidence of Intraoperative Awareness in Indian Patient Population
The profiling of bi-spectral index (BIS) monitored facilitation of general anesthesia (GA), including, anesthesia induction and maintenance of GA depth state, emergence characteristics, and postoperative recovery parameters, is…
- Trial name
- NCT03571945
- Testing
- Bi-spectral Index (BIS QUATRO REF #186-0106), End tidal anaesthesia gas concentration (ETAG)
- Where
- 5 sites in India
- Volunteers
- 2,000 people
- Sponsor
- Sir Ganga Ram Hospital
Delirium, Anesthesia Awareness
Anesthesia Depth Increases Delirium Incidence
This study aimed to determine whether targeting bispectral index (BIS) readings of 55 (light anaesthesia) was associated with a lower incidence of delirium, dementia (POD), POCD and mortality but higher rates of awareness and…
- Trial name
- NCT05656703
- Testing
- BIS guidance of anesthesia, Standard of Care
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Heidelberg University
Remimazolam, Anesthesia Awareness
The Effect of Wavelet Index in Monitoring the Sedation Depth of Remimazolam Besylate
To explore the sedative effect of remimazolam in patients undergoing spinal anesthesia without pain stimulation. Both the Modified Observer's Assessment of Alertness/Sedation (MOAA/S) and the Wavelet index (WLi) were used to…
- Conditions
- Remimazolam, Anesthesia Awareness, Sedative, Hypnotic, or Anxiolytic Withdrawal
- Trial name
- NCT06427785
- Testing
- Remimazolam besylate
- Volunteers
- 30 people
- Sponsor
- Beijing Chao Yang Hospital
Mortality, Surgical Complication
Clinical Outcomes in Adult Patients Undergoing Laparoscopic Surgery Under Neuraxial Anesthesia
The goal of this observational study is to learn about postoperative mortality and postoperative length of stay outcomes after abdominal laparoscopic major surgery.
- Conditions
- Mortality, Surgical Complication, Neurological Complication, Respiratory Complication
- Trial name
- NEURAX (NCT06360666)
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Asst Melegnano e Martesana
Accidental Awareness During General Anesthesia
Comparison of Modulations of Motor Brain Activity and SedLine After Median Nerve Stimulation in General Anesthesia
To this date, no monitoring device can reliably detect episodes of accidental awakening during general anesthesia. One promising approach is the use of electroencephalography (EEG) to detect movement attempts via a brain-computer…
- Trial name
- NCT07267403
- Testing
- EEG Headset, SD LTM STIM (Micromed), SedLine®
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Brugmann University Hospital
Awareness, Anesthesia, Recall Phenomenon
Awareness in Old Aged Patients During Laryngoscopy and Intubation Using Isolated Forearm Technique
Awareness during general anesthesia - that has an incidence between 0.1% and 0.9% of cases and may be more in elderly - remains a concern for anesthesiologists.
- Conditions
- Awareness, Anesthesia, Recall Phenomenon, Inhalation; Gas
- Trial name
- NCT05019560
- Testing
- Sevoflurane, TIVA
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
To Investigate the Incidence and Causes of Awareness During General Anesthesia, To Investigate the of Dreaming During Anesthesia
İntraoperative Awareness Under General Anesthesia
Intraoperative awareness which means the recall of experiences recorded in patients' memories during general anesthesia in the postoperative period is an important issue in anesthesia practice.
- Conditions
- To Investigate the Incidence and Causes of Awareness During General Anesthesia, To Investigate the of Dreaming During Anesthesia, To Investigate the Intra-operative Experiences of Patients Who Report Awareness, To Investigate the Risk Factors That May be Associated With Awareness
- Trial name
- NCT04697732
- Testing
- General anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 30,000 people
- Sponsor
- Baskent University Ankara Hospital
Intraoperative Awareness, Postoperative Pain
Role of Intraoperative Beta Blocker for Morbid Obese Patients Undergoing Laparoscopic Bariatric Surgery
Using esmolol during anesthetic maintenance of laparoscopic bariatric surgery significantly decreases anesthetic, analgesic requirements, postoperative pain, PNV and postoperative hypoxia.
- Trial name
- NCT04086940
- Testing
- Esmolol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Pediatric Cardiac Surgery, Intraoperative Awareness
Closed Loop Propofol Administration in Pediatric Cardiac Surgery
The purpose of the study is to evaluate and compare the feasibility, efficacy and safety of IAADS (Improved Anaesthetic Agent Delivery System) for propofol anaesthesia against manual control using bispectral index in paediatric…
- Conditions
- Pediatric Cardiac Surgery, Intraoperative Awareness, Automated Drug Delivery
- Trial name
- NCT01600287
- Testing
- IAADS, Manual propofol administration
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Anesthesia; Functional, Anesthesia Awareness
The Effect of Minimal Flow Sevoflurane Anesthesia
Our aim is to investigate the effect of minimal flow anesthesia with sevoflurane on hemodynamics and arterial blood gas parameters in laparoscopic cholecystectomy operations.
- Trial name
- NCT04813952
- Testing
- Sevoflurane inhalant product
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Awareness During General Anesthesia
Bispectral Index (BIS) Versus Electronic Alerts in the Prevention of Anesthesia Awareness: the Michigan Awareness Control Study
Awareness during anesthesia is a problem receiving increased attention by patients, clinicians, and the general public. The incidence of intraoperative awareness has been reported to be between 1-2/1000 cases, but recent data…
- Trial name
- MACS (NCT00689091)
- Testing
- Bispectral Index Monitor, Electronic MAC alert
- Where
- United States
- Volunteers
- 22,185 people
- Sponsor
- University of Michigan
Intraoperative Awareness
Comparison of Combined Dexmedetomidine and Ketamine (Ketodex) Versus Dexmedetomidine Alone in Awake Mapping for Deep Brain Stimulation: A Randomized Controlled Trial
Adult patients undergoing awake Deep Brain Stimulation (DBS) surgery for movement disorders (e.g., Parkinson's Disease, Essential Tremor).
- Trial name
- NCT07513935
- Testing
- Ketodex, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Intraoperative Awareness, General Anesthesia
Study to Determine if Patients Exposed to General Anesthesia Significant Numbers of Times Would Increase the Risk for Intraoperative Awareness.
This study will detect whether prior exposure to general anesthesia multiple times is associated with an increased incidence of awareness with explicit recall (AWR).
- Trial name
- EXPLICIT-RCL (NCT05857618)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Chicago
Cesarean Section (MeSH: D002585), Anesthesia
Evaluation of Consciousness Depth (qCON) and Analgesia Depth (qNOX) Indices in General Anesthesia
Objective: This prospective, single-center, observational clinical study aims to evaluate changes in qCON (hypnotic depth), qNOX (nociception/analgesia depth), EMG, and other parameters in patients undergoing elective cesarean…
- Conditions
- Cesarean Section (MeSH: D002585), Anesthesia, Intraoperative Awareness, Analgesia
- Trial name
- NCT07887919
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Kudret Dogru
Anesthesia Awareness
A Study of Human Multi-Sensory Integration
The primary aim of this study is to determine whether spatiotemporal characteristics of multisensory evoked potentials can be used as a marker of consciousness (awareness) under anesthesia.
- Trial name
- MSI (NCT03498391)
- Testing
- Propofol, Ketamine Injectable Product
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania