Clinical trials: Anesthesia,General
Accidental Awareness During General Anesthesia
Prevalence of AAGA
Accidental Awareness During General Anesthesia (AAGA) is a condition where patients regain partial or full consciousness during anesthesia, unable to move or react.
- Trial name
- NCT06759974
- Where
- Turkey (Türkiye)
- Volunteers
- 459 people
- Sponsor
- Marmara University
Intubation, Endotracheal Tube Cuff Pressure
Effect of a Brief Educational Intervention on Endotracheal Tube Cuff Pressure
Endotracheal tube cuff pressure outside the recommended range of 20-30 cmH₂O is common in routine anesthesia practice. Over-inflation can injure the tracheal mucosa, while under-inflation increases the risk of aspiration and…
- Conditions
- Intubation, Endotracheal Tube Cuff Pressure, Anesthesia, Anesthesia,General
- Trial name
- NCT07891195
- Testing
- Brief educational intervention (educational video and reminder posters)
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Airway Management, Supraglottic Airway Device Insertion
Effect of Neuromuscular Blocking Agent Use on Video Laryngeal Mask Airway Insertion
This study aims to investigate whether the administration of a neuromuscular blocking agent (rocuronium) improves the anatomical positioning of a third-generation video laryngeal mask airway (video LMA) in adult patients…
- Conditions
- Airway Management, Supraglottic Airway Device Insertion, Laryngeal Mask Airways, Anesthesia, General
- Trial name
- NCT07894029
- Testing
- Rocuronium, Standard Anesthesia Induction (Propofol and Remifentanil)
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Hacettepe University
Anesthesia, General, Hypotension
Haemodynamic Effects of Four Sevoflurane Wash-In Strategies After Tracheal Intubation
The goal of this clinical trial is to compare how four different ways of starting sevoflurane anaesthesia (the "wash-in" phase) affect the heart and circulation during the first 10 minutes after endotracheal intubation in adults…
- Trial name
- WASH-PRAM (NCT07894393)
- Testing
- End-tidal-controlled sevoflurane wash-in, Low-flow high-concentration wash-in (0.5 L/min, 8% sevoflurane), Low-flow wash-in (1 L/min, 4% sevoflurane)
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Ataturk University
General Anesthesia; Tracheal Intubation
Association of WWI With Difficult Intubation
Difficult intubation remains a clinically significant challenge in anesthetic practice, particularly among patients with obesity and altered body composition.
- Trial name
- WWI (NCT07894692)
- Testing
- Weight, Height, BMI, Waist circumference, WWI, Neck circumference, Mallampati score, Sternomental distance, EGRI score, BMV grade Cormack-Lehane grade,Number of attempts Use of adjunts
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
General Anesthesia Monitoring
Multimodal Monitoring During General Anesthesia in ENT Surgery
This study evaluated whether using several monitoring methods together during general anesthesia could improve patient safety and help anesthesiologists adjust medication doses in adults undergoing ear, nose, and throat (ENT)…
- Trial name
- NCT07895836
- Testing
- Multimodal Anesthesia Monitoring (BIS, SPI, TOF), Standard Anesthesia Monitoring
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Barbara Verro
Any Patient Under General Anesthesia With Propofol Induction
A Novel Two-Step Dosing Induction Strategy (The Propofol Challenge Test) to Minimize Propofol Injection Pain
Propofol is the most widely used intravenous hypnotic agent for the induction of general anesthesia owing to its rapid onset and short duration of action.
- Trial name
- PROTECT (NCT07763548)
- Testing
- Bolus injection, Fractionned onjection
- Where
- Belgium
- Volunteers
- 2,000 people
- Sponsor
- Erasme University Hospital
Gynecologic Surgery, General Anesthesia
Long-term Follow-up of Bio-signals and Quality of Recovery Following Implementation of ERAS Based on the Mobile Application
The goal of this clinical trial is to evaluate the effect of an Enhanced Recovery After Surgery (ERAS) protocol in patients undergoing gynecologic laparoscopic or robotic surgery under general anesthesia.
- Trial name
- NCT07868952
- Testing
- Enhanced Recovery After Surgery, Usual Care
- Where
- South Korea
- Volunteers
- 350 people
- Sponsor
- Wonju Severance Christian Hospital
Airway Management, Anesthesia, General
Video Laryngeal Mask SaCoVLM Versus LMA Supreme and Ambu AuraGain in Children
This randomised controlled trial compares three supraglottic airway devices (laryngeal masks) in children with a body weight of 3-30 kg undergoing elective surgery under general anaesthesia: the SaCoVLM video laryngeal mask (UE…
- Conditions
- Airway Management, Anesthesia, General, Pediatric Anesthesia
- Trial name
- SACOVLM-PEDI (NCT07891832)
- Testing
- SaCoVLM video laryngeal mask, LMA Supreme, Ambu AuraGain
- Where
- Czechia
- Volunteers
- 135 people
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Obesity (BMI>30), General Anesthesia
Frontal EEG Dynamics During Anesthesia in Patients With Obesity and Normal Weight
This prospective observational study aims to compare frontal electroencephalographic (EEG) spectral dynamics between patients with obesity and normal weight undergoing general anesthesia.
- Trial name
- NCT07877090
- Testing
- Frontal Electroencephalography Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Duzce University
General Anesthesia, Testosterone
Comparison of the Effect of Testosterone Administered for Micropenis Hypospadias Surgery With Bispectral Index
The aim of this observational study is to learn the effects of hormone therapy (testosterone) applied in micropenis hypospadias surgery on the depth of anesthesia under general anesthesia.
- Conditions
- General Anesthesia, Testosterone, BIS
- Trial name
- NCT06606496
- Testing
- Bispectral index (BIS)
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Namik Kemal University
Post Operative Pulmonary Complications, Neuromuscular Blockade
Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney Disease
The purpose of the study is to determine which combination of neuromuscular blocking agent and reversal agent is safer to use during anesthesia for patients with chronic kidney disease.
- Conditions
- Post Operative Pulmonary Complications, Neuromuscular Blockade, General Anesthesia
- Trial name
- NCT07203287
- Testing
- Rocuronium, Cisatracurium, Sugammadex
- Where
- United States
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Airway Management, General Anesthesia
Comparison of Three Airway Intubation Devices for First-Attempt Success in General Anesthesia Patients
The goal of this clinical trial is to compare three airway intubation devices in adult patients undergoing general anesthesia who require tracheal intubation.
- Conditions
- Airway Management, General Anesthesia, Tracheal Intubation
- Trial name
- NCT07699653
- Testing
- SPHJ-II, Video lighted stylet, Visual intubation fiberscope
- Where
- China
- Volunteers
- 542 people
- Sponsor
- Guangzhou University of Chinese Medicine
Patients Undergoing General Anesthesia
Deep Neuromuscular Block With Pipecuronium in Patients Undergoing Robotic Thoracic Surgery
Robotic-assisted surgery is rapidly expanding across surgical specialties, including thoracic surgery. Compared with conventional techniques, robotic surgery provides the surgeon with a three-dimensional view and highly precise…
- Trial name
- Deep block (NCT07868094)
- Testing
- Electromiograph
- Where
- Hungary
- Volunteers
- 19 people
- Sponsor
- University of Debrecen
Anesthesia, General, Airway Management
Effect of Laryngeal Mask Cuff Shape on Pharyngeal Stress
Laryngeal masks are widely used supraglottic airway devices, but their cuffs differ considerably in shape and design. The cuff exerts pressure on the pharyngeal structures, which may provoke a physiological stress response and…
- Conditions
- Anesthesia, General, Airway Management, Postoperative Sore Throat
- Trial name
- CUFFSTRESS (NCT07868848)
- Testing
- SaCoVLM video laryngeal mask, LMA Supreme, Ambu AuraGain
- Where
- 2 sites in Czechia
- Volunteers
- 162 people
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Analgesics, Opioid, Anesthesia, General
Asleep Fiberoptic vs Direct Laryngoscopy Effect on Hemodynamic Stability Using Opioid Free Anesthesia Induction
The goal of this clinical trial is to compare heart rate between the fiberoptic and direct oral intubation using opioid free anesthesia induction.
- Conditions
- Analgesics, Opioid, Anesthesia, General, Heart Rate, Blood Pressure
- Trial name
- NCT06487988
- Testing
- direct conventional laryngoscopy, fiberoptic guided intubation
- Where
- Lebanon
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Pediatric Anesthesia, Airway Management
Effective Dose of Alfentanil Combined With Propofol for Laryngeal Mask Airway Insertion in Children
This study uses a prospective, up-and-down sequential allocation method to determine the median effective dose (ED50) and 95% effective dose (ED95) of alfentanil combined with propofol for successful laryngeal mask airway (LMA)…
- Conditions
- Pediatric Anesthesia, Airway Management, General Anesthesia, LMA
- Trial name
- NCT07581665
- Testing
- Alfentanil
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Intraoperative Hypotension, Perioperative Care
Machine Learning-Assisted Management of Intraoperative Hypotension for Personalized Treatment
Intraoperative hypotension, defined as a drop in blood pressure during surgery, is a frequent event in patients undergoing general anesthesia.
- Conditions
- Intraoperative Hypotension, Perioperative Care, Hemodynamic Monitoring, Blood Pressure
- Trial name
- HYPOGUARD (NCT07396636)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Nevsehir Public Hospital
Minimal Flow Anesthesia, General Anaesthesia
Minimal Flow Anesthesia and Infection Risk
This study is being done to find out if the heat and moisture that build up during minimal flow anesthesia can lead to the growth of germs (microorganisms) inside the anesthesia equipment.
- Conditions
- Minimal Flow Anesthesia, General Anaesthesia, Inhalation Anesthesia, Infection Risk
- Trial name
- NCT07092046
- Testing
- Sevoflurane (Volatile Anesthetic), Propofol 1%, Remifentanil 2 MG
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
General Anesthesia, Hemodynamics
Effect of Operating Room Noise on BIS and Hemodynamics Under General Anesthesia
This prospective observational study aims to evaluate the impact of operating room noise on bispectral index (BIS) and hemodynamic parameters in patients undergoing general anesthesia.
- Conditions
- General Anesthesia, Hemodynamics, Noise Exposure
- Trial name
- NCT07194707
- Testing
- Intraoperative Noise Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital