Clinical trials: Alcohol and Other Drug Use Disorders
Substance Use, Severe Mental Disorder
Validation of the Dutch Translation of the Tobacco, Alcohol, Prescription Medication and Other Substances (TAPS)-Tool
The aim of the study is to investigate the reliability and validity of the Dutch version of the TAPS-tool. This will be investigated in 2 groups: patients without intellectual disabilities treated in Flexible Assertive Community…
- Conditions
- Substance Use, Severe Mental Disorder, Intellectual Disability, Mild
- Trial name
- NCT05273021
- Testing
- TAPS
- Where
- 3 sites in Netherlands
- Volunteers
- 150 people
- Sponsor
- Birgit Seelen-de Lang
Drug Use Disorders, Illicit Drug Use
An Initial Study of the Implementation of Digital Therapeutics for Substance Use Disorders in Primary Care
The DIGITS Trial addresses a critical knowledge gap: How to best implement digital treatments for opioids and other substance use disorders in primary care.
- Conditions
- Drug Use Disorders, Illicit Drug Use, Alcohol-Related Disorders
- Trial name
- DIGITS Pilot (NCT04907045)
- Testing
- Health Coaching, Practice Facilitation, Standard Implementation
- Where
- United States
- Volunteers
- 1,552 people
- Sponsor
- Kaiser Permanente
Alcohol and Other Drug Use Disorders
Texas Family Health Patterns: A Study Across Generations
The researchers are studying factors that may increase the risk for alcohol and drug use in individuals who do not have any problems with these substances.
- Trial name
- NCT02438254
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Stress Disorders, Post-Traumatic, Substance-Related Disorders
Concurrent Treatment for Substance Dependent Individuals With Post-Traumatic Stress Disorder (PTSD)
This treatment intervention trial is designed for men and women with substance dependence and comorbid Post-Traumatic Stress Disorder (PTSD).
- Trial name
- NCT01365247
- Testing
- Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure, Relapse Prevention Treatment, Active Monitoring Control Group
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- The City College of New York
Asperger's Disorder, Asperger Disorder
QAIAx (AIhealth4U) - AI Smart Health Cities: Microcity Enclave Program (Quantum AI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum AI/AGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Substance Use, Stress
Automating Peer Learning to Reduce Alcohol Use and Related Deviant Behavior in Secondary School
Deviant peer affiliation is one of the most important predictors of alcohol use in adolescence. These affiliations arise when socially marginalized youth self-aggregate and reinforce alcohol use and other deviant activity (i.e.…
- Conditions
- Substance Use, Stress, Relation, Interpersonal, Bullying
- Trial name
- PeerLearning (NCT04478240)
- Testing
- PeerLearning.net
- Where
- United States
- Volunteers
- 924 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Tobacco Use Disorder, Alcohol Use Disorder
Family-Skills Training to Prevent Tobacco and Other Substance Use in Latino Youth
The goal of this project is to evaluate the effectiveness of a family-based tobacco use prevention intervention directed at immigrant Latino parents of middle school aged youth as delivered in partnership with seven community…
- Conditions
- Tobacco Use Disorder, Alcohol Use Disorder, Drug Use Disorder, Smoking
- Trial name
- NCT01442753
- Testing
- Family-Skills Training
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Depression - Major Depressive Disorder, Schizophenia Disorder
A Novel Blood Test as a Biomarker in Mental Health
This longitudinal, observational study aims to assess whether the characteristics of a novel blood peripheral biomarker can serve as indicators for depression and schizophrenia in patients at the Royal Columbian Hospital…
- Conditions
- Depression - Major Depressive Disorder, Schizophenia Disorder, Psychosis, Mania (Neurotic)
- Trial name
- LEADING-MH (NCT06856161)
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Fraser Health
Depression, Substance Use
Group CBT for Depression and AOD Disorders
The investigators will adapt and test an existing treatment (group CBT for depression) for use in outpatient substance use treatment settings as delivered by trained substance use counselors.
- Trial name
- BRIGHT2 (NCT01154309)
- Testing
- Group CBT for Depression and AOD Disorders
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- RAND
Alcohol Abuse, Drug Abuse
Adolescent Family-Based Alcohol Prevention
This study explores whether giving families a choice of family-based prevention programs to prevent adolescent alcohol use will make a difference in program recruitment, retention, completion, as well as adolescent outcomes.
- Trial name
- NCT00858065
- Testing
- Strengthening Families Program (SFP), Family Matters
- Where
- 2 sites in United States
- Volunteers
- 1,228 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Substance Use
Cultural Adaptation of Drug Treatment for DJJ Youth
This project aims to improve the understanding of the impact of Ethnic and Racial Discrimination (ERD) on adolescent alcohol and other drug use (AOD) within the Black Justice-Involved Youth (JIY) population.
- Trial name
- CAST (NCT06003725)
- Testing
- Culturally Adapted Adolescent Substance Use Treatment
- Where
- 2 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Post-Traumatic Stress Symptoms, Problematic Use of Alcohol or Other Drugs
Web-based CBT for Recent Veterans Experiencing Problems With Trauma Symptoms or Alcohol/Drug Use
The proposed study involves developing and evaluating an interactive, web-based CBT intervention for OEF/OIF Veterans with hazardous or problematic substance use and PTSD symptoms (PTSD or subsyndromal PTSD).
- Trial name
- Web CBT (NCT01710943)
- Testing
- Web-based Cognitive Behavioral Treatment
- Where
- 2 sites in United States
- Volunteers
- 216 people
- Sponsor
- National Development and Research Institutes, Inc.
Substance-related Disorders, Alcohol and Other Substance Use Prevention
Evaluating Feasibility, Acceptability, Usability, and an Initial Estimate of Effect of a Novel Training Platform on Peer Recovery Supporter Skill, Adherence, and Knowledge Gain-Phase I
This pilot study evaluates the feasibility, usability, and acceptability of the Thrive Digital Peer Platform (TDPP), an online training system for Peer Recovery Support Specialists (PRSS).
- Conditions
- Substance-related Disorders, Alcohol and Other Substance Use Prevention, Alcohol and Other Drug Use Disorders
- Trial name
- NCT07090590
- Testing
- Thrive Digital Peer Platform (TDPP)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Thrive Digital Health, LLC
Recreational Drug Use, Sexual Violence
Evaluation of Teen Connection Project for Trans and Gender Minority Youth
The purpose of this project is to develop and evaluate an online mentoring and skill-building program for transgender and/or gender minority youth (TGMY) ages 14 to 18, the Teen Connection Project (TCP).
- Conditions
- Recreational Drug Use, Sexual Violence, Victimisation, Depressive Symptoms
- Trial name
- TCP (NCT06587139)
- Testing
- Teen Connection Project (TCP)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Depression, Substance Use
Building Recovery By Improving Goals, Habits, and Thoughts
The investigators will investigate whether group Cognitive Behavioral Therapy (CBT) for depression, with alcohol and other drug (AOD) treatment counselors leading the groups, is effective and cost effective in treating…
- Trial name
- BRIGHT (NCT01191788)
- Testing
- Group Cognitive Behavioral Therapy, Group CBT for Depression
- Where
- United States
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- RAND
Alcohol Abuse, Drug Use
The Weaving Healthy Families Program
Alcohol and other drug (AOD) abuse and violence in families are co-occurring risk factors that drive health disparities and mortality among Native Americans (NA), making the long-term goal of this research is to promote health…
- Conditions
- Alcohol Abuse, Drug Use, Violence, Domestic, Child Abuse
- Trial name
- NCT03924167
- Testing
- Weaving Healthy Families Program
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tulane University
Substance Use Disorder
The Tobacco, Alcohol, Prescription Medication and Other Substances Tool
The purpose of the study is to develop and validate a questionnaire to screen and assess adult primary care patients for tobacco, alcohol, prescription drug, and drug use and problems related to their use.
- Trial name
- CTN0059 (NCT02110693)
- Testing
- Interviewer and tablet administration of the TAPS Tool
- Where
- 4 sites in United States
- Volunteers
- 2,057 people, healthy volunteers welcome
- Sponsor
- Friends Research Institute, Inc.
Drug Use Disorders, Illicit Drug Use
Digital Treatments for Opioids and Other Substance Use Disorders in Primary Care
The DIGITS Trial addresses a critical knowledge gap: How to best implement digital treatments for opioids and other substance use disorders in primary care.
- Conditions
- Drug Use Disorders, Illicit Drug Use, Alcohol-Related Disorders, Opioid Use Disorder
- Trial name
- DIGITS (NCT05160233)
- Testing
- Standard implementation, Health Coaching, Practice Facilitation
- Where
- United States
- Volunteers
- 18,430 people
- Sponsor
- Kaiser Permanente
Alcohol or Other Drugs Use
HealthCall-S: A Pilot Study Targeting Concurrent Non-injection Drug Use and Alcohol in HIV Primary Care Clinics
This pilot study goal is to compare two different treatments to help HIV positive patients reduce their concurrent drinking and non-injection drug use.
- Trial name
- NCT02294318
- Testing
- HealthCall+Motivational Interviewing, Motivational Interviewing
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Research Foundation for Mental Hygiene, Inc.
Alcoholism, HIV Infections
Venue-Based Couples CoOp in South Africa
Couples who use alcohol and other drugs (AOD) in South Africa are at high risk for engaging in risky sex behavior within their relationships and with other sexual partners.
- Trial name
- Couples CoOp (NCT01121692)
- Testing
- Couples Intervention, Women's CoOp, Women's CoOp and Men's Intervention
- Where
- South Africa
- Volunteers
- 600 people
- Sponsor
- RTI International