Clinical trials: Alcohol Drinking, active
Alcohol Use and Intimate Partner Violence
Adjunctive Motivational Alcohol Intervention to Prevent IPV
This is a study to provide much-needed experimental data on the efficacy of a brief alcohol Motivational Enhancement Therapy (MET) pre-group intervention for Veterans receiving group treatment for IPV perpetration.
- Trial name
- MET-SAH (NCT05287711)
- Testing
- Motivational Enhancement Therapy, Alcohol Education Control, Treatment as Usual
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- VA Office of Research and Development
Alcohol Use Disorder
Spironolactone in Alcohol Use Disorder (SAUD)
Background: Alcohol use disorder (AUD) affects about 29.5 million people in the United States. Only 3 medicines have been approved by Food and Drug Administration to treat AUD. Researchers want to find better treatments for AUD.
- Trial name
- NCT05807139
- Testing
- Spironolactone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Alcohol Drinking, Self Efficacy
ChangeGradients: Promoting Adolescent Health Behavior Change
As most adolescents visit a healthcare provider once a year, health behavior change interventions linked to clinic-based health information technologies hold significant promise for improving healthcare quality and subsequent…
- Conditions
- Alcohol Drinking, Self Efficacy, Adolescent Behavior, Risk-Taking
- Trial name
- NCT04110756
- Testing
- ChangeGradients
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Alcohol Use, Cannabis Use
MATAspire: Mental Health Awareness Tailored App for Substance Prevention and Integrated Resilience Education
The MATAspire intervention is a web-app designed to promote substance misuse prevention education and bolster protective coping skills whereby students complete six weekly interactive modules using a smart device or computer.
- Conditions
- Alcohol Use, Cannabis Use, Nicotine Use, Illicit Drug Use
- Trial name
- MATAspire (NCT06553196)
- Testing
- MATAspire Web-app
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- California State University, Northridge
Emotional Regulation, Alcohol Drinking in College
Momentary Coping Prompts and Hair Steroids in College Students
This study looks at the moments when college students feel a strong emotional swing, and how those moments relate to reacting online when upset, drinking alcohol, and eating in response to emotions.
- Conditions
- Emotional Regulation, Alcohol Drinking in College, Emotional Eating, Aggression
- Trial name
- REACT-Bio (NCT07782398)
- Testing
- Momentary coping prompt, Active control message
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Florida
Emotional Regulation, Alcohol Drinking in College
Just-in-Time Coping Prompts for Reactive Digital Behavior in College Students
This study looks at the moments when college students feel a strong emotional swing, and how those moments relate to reacting online when upset, drinking alcohol, and eating in response to emotions.
- Conditions
- Emotional Regulation, Alcohol Drinking in College, Emotional Eating, Aggression
- Trial name
- REACT (NCT07789314)
- Testing
- Momentary coping prompt, Active control message
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Florida
Substance Use Disorders, HIV Infections
Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People
This is a multi-phased study, funded through a National Institute on Drug Abuse (NIDA) K24 grant that aims to ultimately refine a virtual reality tool through qualitative and quantitative research targeting HIV and substance…
- Trial name
- NCT05816083
- Testing
- Virtual Reality Tool
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
HIV-1-infection, Alcohol Drinking
Acceptance and Commitment Therapy for HIV+ Hazardous Drinkers
Alcohol consumption is a critical factor in HIV treatment that significantly contributes to poor treatment-related outcomes. Randomized clinical trials (RCTs) of alcohol interventions for people with HIV (PWH) have had limited…
- Trial name
- NCT06648629
- Testing
- Acceptance and Commitment Therapy (ACT), Brief Alcohol Intervention
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Syracuse University
Breast Cancer, Alcohol Drinking
Implementing a Digital Alcohol Intervention to Raise Women's Awareness of Alcohol-related Breast Cancer Risk During Routine Screening Visits
This study is a single-arm feasibility trial evaluating a digital behavioral intervention designed to increase women's awareness of the relationship between alcohol use and breast cancer risk during routine breast cancer…
- Trial name
- NCT07799467
- Testing
- Sobriety Digital Intervention
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Miami
Cancer
Cancer Prevention for Young Rural Adults
Young adults aged 18-26 engage in a number of behaviors that increase their risk of developing cancer later in life including sedentary lifestyles, unhealthy eating, nicotine produce us, heavy drinking of alcohol, increased UV…
- Trial name
- NCT05618158
- Testing
- 4 Corners Rural Health Cancer Prevention
- Where
- 5 sites in United States
- Volunteers
- 1,796 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Alcohol Abuse, Alcohol Use Disorder
A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their Partners
The purpose of this study is to evaluate the efficacy of an adaptive web intervention (Partners Connect) on military spouse drinking behaviors (CPs) and service member help-seeking (SMs).
- Conditions
- Alcohol Abuse, Alcohol Use Disorder, Alcohol Drinking, Relations, Interpersonal
- Trial name
- NCT05619185
- Testing
- CRAFT Web-Based Intervention, Phone-Based CRAFT, CRAFT Workbook
- Where
- United States
- Volunteers
- 744 people, healthy volunteers welcome
- Sponsor
- Stanford University
Ketosis, Alcohol Drinking
Effects of Ketone Supplement and Alcohol on Brain Metabolism
The research study is being conducted to better understand the effects of ketones and alcohol on brain functioning and brain metabolism.
- Conditions
- Ketosis, Alcohol Drinking, MRI
- Trial name
- NCT06815237
- Testing
- Kenetik, Alcohol beverage
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Postpartum Depression (PPD), Alcohol Use
Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms
This study aims to learn about depression and alcohol use in postpartum mothers and whether an intervention based on contingency management and problem-solving therapy (CM-PST) can help reduce these symptoms.
- Conditions
- Postpartum Depression (PPD), Alcohol Use, Contingency Management, Problem Solving Therapy
- Trial name
- MOMS-AD (NCT07485036)
- Testing
- Contingency Management & Problem Solving Therapy, Usual Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Illinois at Chicago
Alcohol Use, Underage Drinking
Parent-Focused Alcohol Prevention Program for Hispanic Families in Faith-Based Settings
The goal of this clinical trial is to determine whether Guiando Buenas Decisiones, a parent-focused alcohol prevention program, can help prevent or delay alcohol initiation and use among Hispanic immigrant adolescents ages 12 to…
- Conditions
- Alcohol Use, Underage Drinking, Parenting Intervention, Prevention
- Trial name
- NCT07869550
- Testing
- Guiando Buenas Decisiones (GBD)
- Where
- United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Alcohol Consumption, Sexual Assault
uSafeUS+ App Pilot Testing
The purpose of this study is to test the feasibility and acceptability of an innovative mobile application (uSafeUS+) to reduce college student drinking and sexual assault (SA) risk in real time.
- Trial name
- NCT07557745
- Testing
- uSafeUS+, uSafeUS
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Florida
Alcohol Drinking, Drinking Behavior
Reducing Cardiovascular Risks: The Role of Alcohol Use
The purpose of this study is to learn whether avoiding alcohol can improve heart and blood vessel health in adults who regularly drink alcohol and have high blood pressure.
- Conditions
- Alcohol Drinking, Drinking Behavior, At-risk Drinking, Cardiovascular Risk Factor
- Trial name
- NCT07783061
- Testing
- Alcohol Abstinence, Control arm
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- The University of Texas at Arlington
Alcohol Drinking, Cannabis Use
Cannabis' Impact on Alcohol Consumption
This study employs a repeated measures experimental design to examine the effect of THC-dominant dose of cannabis and CBD-dominant dose of cannabis, relative to placebo, on subsequent drinking in an alcohol choice task in which…
- Conditions
- Alcohol Drinking, Cannabis Use, Cannabis, Alcohol Use Disorder
- Trial name
- NCT05389930
- Testing
- THC-dominant cannabis, CBD-dominant cannabis, Alcohol
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Brown University
Domestic Violence, Post Traumatic Stress Disorder
Evaluation of a Trauma-Informed Partner Violence Intervention Program
The goal of this study is to conduct a randomized controlled trial (RCT) comparing outcomes between two programs to reduce intimate partner violence (IPV)- the Strength at Home (SAH) program and a standard, state-approved IPV…
- Trial name
- NCT06803043
- Testing
- SAH, TAU
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Boston University
HIV Infections, Alcohol Drinking
Precision Microbiota Interventions for Senoreduction Trial
People with HIV who drink alcohol are at increased risk for accelerated aging biology, including increased immune senescence. This randomized, double-blind, crossover clinical trial evaluates two generally recognized as safe…
- Conditions
- HIV Infections, Alcohol Drinking, Aging, Immunosenescence
- Trial name
- PreMIS (NCT07462767)
- Testing
- Limosilactobacillus reuteri, Blueberry extract
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Alcohol Drinking
Nicotinic Receptor Genetic Variation and Alcohol Reward
Background: People with the brain disease AUD (alcohol use disorder) have a serious problem with drinking. Researchers want to study how different people react to alcohol, and how genes affect this.
- Trial name
- NCT03294460
- Testing
- Alcohol (Oral), Alcohol (IV), Alcohol (Ethanol)
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)