CancerNCT05618158
Cancer Prevention for Young Rural Adults
A study testing 4 Corners Rural Health Cancer Prevention in people with Cancer, run by Klein Buendel, Inc. at 5 sites in United States.
Trial summary
Young adults aged 18-26 engage in a number of behaviors that increase their risk of developing cancer later in life including sedentary lifestyles, unhealthy eating, nicotine produce us, heavy drinking of alcohol, increased UV exposure, and incomplete uptake of HPV vaccination. Read more about this study
- Who is it for?
- Ages 18 to 26 yearsHealthy volunteers can take part
- Conditions the study is for
- Cancer
- What is being tested?
- 4 Corners Rural Health Cancer Prevention
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 1,796 participants
- Where
- 5 sitesUnited States
- Study dates
- 20 Apr 2024to 31 Aug 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 26 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Aged 18-26 years old
- Resides in a county coded as RUCC 4-9 in Arizona, Colorado, New Mexico, or Utah
- Able to speak and read English
- Has regular social media engagement
- Accepts screening call from study staff
- Consents to participate
Who cannot join
- Participated in community engagement activities
- Cannot speak and read English
- Has low or no social media engagement
- Does not accept a screening call from study staff
- Does not consent to participate
- Does not give permission for engagement data to be extracted from Facebook private group
- If biologically female, currently pregnant
Trial locations and contacts
5 sites in 1 country.
5 sites in 1 country
United States5 sites
University of New Mexico
Albuquerque, New Mexico, 87131-0001
University of Colorado Denver
Aurora, Colorado, 80045-2570
Colorado State University
Fort Collins, Colorado, 80521-4593
University of Utah
Salt Lake City, Utah, 84112-5550
University of Arizona
Tucson, Arizona, 85719
About this study
Official title: #4Corners4Health: A Social Media Cancer Prevention Program for Rural Emerging Adults
Young adults aged 18-26 engage in a number of behaviors that increase their risk of developing cancer later in life including sedentary lifestyles, unhealthy eating, nicotine produce us, heavy drinking of alcohol, increased UV exposure, and incomplete uptake of HPV vaccination. A multi-risk factor campaign will be developed to reduce these cancer risk behaviors and delivered to young adults over social media, a popular channel that can reach nearly all young adults. The campaign will be evaluated for effectiveness in a rigorous randomized trial with measures of moderate to vigorous physical activity, healthy eating patterns, nicotine product use, alcohol intake, sunburn prevalence, and HPV vaccination uptake.
Read the detailed description
Several risk factors are prevalent during early adulthood that can lead to cancer later in life. Emerging adults (EAs) aged 18-26 residing in rural areas of the United States engage in many cancer risk behaviors, especially sedentary lifestyles, poor eating patterns, nicotine product use, excess alcohol intake, infrequent sun protection, and inadequate uptake of the HPV vaccine. This application responds to RFA-CA-20-051, "Social and Behavioral Intervention Research to Address Modifiable Risk Factors for Cancer in Rural Populations." The goal is to improve cancer risk behavioral factors among diverse EAs aged 18-26 living in rural counties in the Four Corners states, a unique, underserved region, using a social media campaign designed with community advisors. EAs, including in rural communities, are heavy consumers of online content, especially over social media, and social media provide responsive, engaging, and low-cost platforms for distributing cancer prevention information with high dissemination potential. But, social media also circulate inaccurate, misleading, and harmful information. The specific aims of this research are to: 1) Develop a social media intervention for diverse EAs in rural communities via a community-engaged process that combines expert advice, user-generated content, and online instruction to communicate about behavioral cancer risks, cancer misinformation, counter marketing, digital and media literacy, and family communication; 2) evaluate the effect of a theory-based social media intervention on moderate to vigorous physical activity (MVPA), healthy eating patterns, nicotine product use, alcohol intake, sunburn prevalence, and HPV vaccination with the diverse population of EAs aged 18-26 in rural counties in AZ, CO, NM, and UT (Four Corners states) recruited from Qualtrics' survey panel and enrolled in a pragmatic randomized trial using a stepped-wedge design in which individual EAs will be randomized to 1 of 4 cohorts and receive the social media feed for varying durations in separate Facebook private groups; 3) test if improvements in EAs' cancer risk knowledge and beliefs, digital and media literacy skills, accurate cancer prevention information, and family communication mediate impact of the social media campaign; and 4) explore whether the impact of the social media campaign differs according to: a) level of EAs' engagement with campaign, b) cancer risk factors, and c) biological sex of the participants (as required by NIH). The research is innovative because it tests a theory-based, multi-risk factor approach to cancer prevention with diverse EAs in rural counties, an under-studied population, in a very popular new media. Social media may reach EAs more than interventions through other community channels (e.g., clinics, schools, and workplaces) and for lower cost in the geographically-dispersed, underserved rural communities in the Mountain West. The overall impact is extremely high because it will aid rural EAs in making informed decisions that reduce cancer risk factors and prevent cancer later in life and help EAs critically evaluate and resist misinformation and marketing that promote cancer risk behaviors.
- Conditions
- Cancer
- Being tested
- 4 Corners Rural Health Cancer Prevention
- Keywords
- social media, cancer prevention, nicotine use, physical activity, nutrition, sun protection, alcohol use, HPV vaccine, media literacy
- Medical subject headings
- Neoplasms, Motor Activity, Alcohol Drinking
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
4 Corners Rural Health Cancer PreventionBehavioural
Participants, aged 18-26, will join a private Facebook group to participate in the intervention. The group is not viewable to the public, including other Facebook users. Content that focuses on cancer prevention behaviors will be posted twice per day for up to 12 months. Each group will be hosted by a moderator who is responsible for managing the intervention goals and participants' engagement.
| Study group | Role | What they receive |
|---|---|---|
| 4 Corners Rural Cancer Prevention | Experimental | Four separate Facebook groups, which provide information via posts within the private groups about cancer risk factors (e.g. reducing alcohol consumption, tobacco use cessation, increasing physical activity), behavioral skills to reduce them, benefits of, social support for, and ways to reduce social/financial costs of cancer prevention, and advice from health care providers to decrease barriers. Posts will seek to improve self- and response-efficacy and perceived risk, and link cancer prevention to personal goals. Receives: Behavioral: 4 Corners Rural Health Cancer Prevention |
What is being measured
The primary outcome is the main question the study is designed to answer.
Physical Activity
Participants will self-report minutes per week of moderate to vigorous physical activity.
Measured: Baseline
Physical Activity
Participants will self-report minutes per week of moderate to vigorous physical activity.
Measured: 3 months
Physical Activity
Participants will self-report minutes per week of moderate to vigorous physical activity.
Measured: 12 months
Physical Activity
Participants will self-report minutes per week of moderate to vigorous physical activity.
Measured: 24 months
Diet
Participants will self-report intake per day of fruits, vegetables, whole grains/fiber, added sugars (from sugar-sweetened beverages), and red/processed meats.
Measured: Baseline
Diet
Participants will self-report intake per day of fruits, vegetables, whole grains/fiber, added sugars (from sugar-sweetened beverages), and red/processed meats.
Measured: 3 months
Diet
Participants will self-report intake per day of fruits, vegetables, whole grains/fiber, added sugars (from sugar-sweetened beverages), and red/processed meats.
Measured: 12 months
Diet
Participants will self-report intake per day of fruits, vegetables, whole grains/fiber, added sugars (from sugar-sweetened beverages), and red/processed meats.
Measured: 24 months
Nicotine Product Use
Participants will self-report tobacco/nicotine use in the past 30 days (every day, some days, not at all).
Measured: Baseline
Nicotine Product Use
Participants will self-report tobacco/nicotine use in the past 30 days (every day, some days, not at all).
Measured: 3 months
Nicotine Product Use
Participants will self-report tobacco/nicotine use in the past 30 days (every day, some days, not at all).
Measured: 12 months
Nicotine Product Use
Participants will self-report tobacco/nicotine use in the past 30 days (every day, some days, not at all).
Measured: 24 months
Alcohol Intake
Participants self-report consumption of number of alcoholic drinks in the past 30 days.
Measured: Baseline
Alcohol Intake
Participants self-report consumption of number of alcoholic drinks in the past 30 days.
Measured: 3 months
Alcohol Intake
Participants self-report consumption of number of alcoholic drinks in the past 30 days.
Measured: 12 months
Alcohol Intake
Participants self-report consumption of number of alcoholic drinks in the past 30 days.
Measured: 24 months
Uv Exposure
Participants will self-report number of sunburns.
Measured: Baseline
Uv Exposure
Participants will self-report number of sunburns.
Measured: 3 months
Uv Exposure
Participants will self-report number of sunburns.
Measured: 12 months
Uv Exposure
Participants will self-report number of sunburns.
Measured: 24 months
HPV Vaccination
Participants will self-report whether or not they have received one or more doses of the HPV vaccine.
Measured: Baseline
HPV Vaccination
Participants will self-report whether or not they have received one or more doses of the HPV vaccine.
Measured: 3 months
HPV Vaccination
Participants will self-report whether or not they have received one or more doses of the HPV vaccine.
Measured: 12 months
HPV Vaccination
Participants will self-report whether or not they have received one or more doses of the HPV vaccine.
Measured: 24 months
Secondary outcomes (28)
Physical Activity
Participants will self-report number of minutes per week engaging in physical activity to determine if they meet the 150 minutes per week recommendation.
Measured: Baseline
Physical Activity
Participants will self-report number of minutes per week engaging in physical activity to determine if they meet the 150 minutes per week recommendation.
Measured: 3 months
Physical Activity
Participants will self-report number of minutes per week engaging in physical activity to determine if they meet the 150 minutes per week recommendation.
Measured: 12 months
Physical Activity
Participants will self-report number of minutes per week engaging in physical activity to determine if they meet the 150 minutes per week recommendation.
Measured: 24 months
Diet
Participants will self-report frequency of eating meals away from home/fast food.
Measured: Baseline
Diet
Participants will self-report frequency of eating meals away from home/fast food.
Measured: 3 months
Diet
Participants will self-report frequency of eating meals away from home/fast food.
Measured: 12 months
Diet
Participants will self-report frequency of eating meals away from home/fast food.
Measured: 24 months
Nicotine Product Use
Participants will self-report tobacco/nicotine use in the past 7 days (every day, some days, not at all).
Measured: Baseline
Nicotine Product Use
Participants will self-report tobacco/nicotine use in the past 7 days (every day, some days, not at all).
Measured: 3 months
Nicotine Product Use
Participants will self-report tobacco/nicotine use in the past 7 days (every day, some days, not at all).
Measured: 12 months
Nicotine Product Use
Participants will self-report tobacco/nicotine use in the past 7 days (every day, some days, not at all).
Measured: 24 months
Nicotine Product Use
Participants will self-report readiness to quit using a 10 point rating scale (1=no thought of quitting; 10=taking action to quit).
Measured: Baseline
Nicotine Product Use
Participants will self-report readiness to quit using a 10 point rating scale (1=no thought of quitting; 10=taking action to quit).
Measured: 3 months
Nicotine Product Use
Participants will self-report readiness to quit using a 10 point rating scale (1=no thought of quitting; 10=taking action to quit).
Measured: 12 months
Nicotine Product Use
Participants will self-report readiness to quit using a 10 point rating scale (1=no thought of quitting; 10=taking action to quit).
Measured: 24 months
Alcohol Intake
Participants will self-report number of times binge drinking in the past 30 days.
Measured: Baseline
Alcohol Intake
Participants will self-report number of times binge drinking in the past 30 days.
Measured: 3 months
Alcohol Intake
Participants will self-report number of times binge drinking in the past 30 days.
Measured: 12 months
Alcohol Intake
Participants will self-report number of times binge drinking in the past 30 days.
Measured: 24 months
UV Exposure
Participants will self-report sun protection behaviors with percent of sun exposure hours using sun protection.
Measured: Baseline
UV Exposure
Participants will self-report sun protection behaviors with percent of sun exposure hours using sun protection.
Measured: 3 months
UV Exposure
Participants will self-report sun protection behaviors with percent of sun exposure hours using sun protection.
Measured: 12 months
UV Exposure
Participants will self-report sun protection behaviors with percent of sun exposure hours using sun protection.
Measured: 24 months
HPV Vaccination
Participants will self-report if they have completed the series of HPV vaccination by receiving 3 doses of the vaccine.
Measured: Baseline
HPV Vaccination
Participants will self-report if they have completed the series of HPV vaccination by receiving 3 doses of the vaccine.
Measured: 3 months
HPV Vaccination
Participants will self-report if they have completed the series of HPV vaccination by receiving 3 doses of the vaccine.
Measured: 12 months
HPV Vaccination
Participants will self-report if they have completed the series of HPV vaccination by receiving 3 doses of the vaccine.
Measured: 24 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Nov 2022
- Study start20 Apr 2024
- Primary completion31 Mar 2027 (estimated)
- Study completion31 Aug 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for CancerStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- Randomized stepped-wedge with four cohorts
- Masking
- None (open label)
- Enrolment
- 1,796 participants (actual)
Sponsor and investigators
- Lead sponsor
- Klein Buendel, Inc.
- Sponsor type
- Industry (pharma, biotech, devices)
- Collaborators
- National Cancer Institute (NCI), University of Arizona, University of Utah, Colorado State University, University of Colorado, Denver, University of New Mexico
- Responsible party
- Sponsor
- Investigators
- David Buller, PhD, Principal investigator, Klein Buendel, Inc.
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05618158
- Sponsor's protocol ID
- 0341/0353
- Other IDs
- 1R01CA268037-01A1, 4R01CA268037-04, 5R01CA268037-03, 5R01CA268037-02
- Status last verified
- Oct 2026
- First submitted
- 8 Nov 2022
- Last updated
- 19 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Warner EL, Kinsey A, Walkosz BJ, Berteletti J, Nuss K, Small A, Woodall WG, Kepka D, Taren D, Skiba MB, Guest DD, Blair CK, Gordon JS, Wetter DW, Borrayo EA, Henry KL, Sussman AL, Buller DB. A Web-Based Cancer Prevention Intervention for Rural Emerging Adults: Mixed Methods Development and Pilot-Testing Study. J Med Internet Res. 2026 Jan 8;28:e80803. doi: 10.2196/80803.
PubMed 41505184Buller DB, Sussman AL, Thomson CA, Kepka D, Taren D, Henry KL, Warner EL, Walkosz BJ, Woodall WG, Nuss K, Blair CK, Guest DD, Borrayo EA, Gordon JS, Hatcher J, Wetter DW, Kinsey A, Jones CF, Yung AK, Christini K, Berteletti J, Torres JA, Barraza Perez EY, Small A. #4Corners4Health Social Media Cancer Prevention Campaign for Emerging Adults: Protocol for a Randomized Stepped-Wedge Trial. JMIR Res Protoc. 2024 Feb 22;13:e50392. doi: 10.2196/50392.
PubMed 38386396
Study at a glance
From the registry record, last updated by the sponsor on 19 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- #4Corners4Health: A Social Media Cancer Prevention Program for Rural Emerging Adults
- ClinicalTrials.gov ID
- NCT05618158
- Acronym / sponsor ID
- 0341/0353
- Conditions
- Cancer
- Keywords
- social media, cancer prevention, nicotine use, physical activity, nutrition, sun protection, alcohol use, HPV vaccine
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 1,796 participants (actual)
- Lead sponsor
- Klein Buendel, Inc.Industry (pharma, biotech, devices)
- Collaborators
- National Cancer Institute (NCI), University of Arizona, University of Utah, Colorado State University, University of Colorado, Denver, University of New Mexico
- Study start
- 20 Apr 2024 (actual)
- Primary completion
- 31 Mar 2027 (estimated)
- Study completion
- 31 Aug 2027 (estimated)
- First posted
- 16 Nov 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Young adults aged 18-26 engage in a number of behaviors that increase their risk of developing cancer later in life including sedentary lifestyles, unhealthy eating, nicotine produce us, heavy drinking of alcohol, increased UV exposure, and incomplete uptake of HPV vaccination. A multi-risk factor campaign will be developed to reduce these cancer risk behaviors and delivered to young adults over social media, a popular channel that can reach nearly all young adults. The campaign will be evaluated for effectiveness in a rigorous randomized trial with measures of moderate to vigorous physical activity, healthy eating patterns, nicotine product use, alcohol intake, sunburn prevalence, and HPV vaccination uptake.
Detailed description
Several risk factors are prevalent during early adulthood that can lead to cancer later in life. Emerging adults (EAs) aged 18-26 residing in rural areas of the United States engage in many cancer risk behaviors, especially sedentary lifestyles, poor eating patterns, nicotine product use, excess alcohol intake, infrequent sun protection, and inadequate uptake of the HPV vaccine. This application responds to RFA-CA-20-051, "Social and Behavioral Intervention Research to Address Modifiable Risk Factors for Cancer in Rural Populations." The goal is to improve cancer risk behavioral factors among diverse EAs aged 18-26 living in rural counties in the Four Corners states, a unique, underserved region, using a social media campaign designed with community advisors. EAs, including in rural communities, are heavy consumers of online content, especially over social media, and social media provide responsive, engaging, and low-cost platforms for distributing cancer prevention information with high dissemination potential. But, social media also circulate inaccurate, misleading, and harmful information. The specific aims of this research are to: 1) Develop a social media intervention for diverse EAs in rural communities via a community-engaged process that combines expert advice, user-generated content, and online instruction to communicate about behavioral cancer risks, cancer misinformation, counter marketing, digital and media literacy, and family communication; 2) evaluate the effect of a theory-based social media intervention on moderate to vigorous physical activity (MVPA), healthy eating patterns, nicotine product use, alcohol intake, sunburn prevalence, and HPV vaccination with the diverse population of EAs aged 18-26 in rural counties in AZ, CO, NM, and UT (Four Corners states) recruited from Qualtrics' survey panel and enrolled in a pragmatic randomized trial using a stepped-wedge design in which individual EAs will be randomized to 1 of 4 cohorts and receive the social media feed for varying durations in separate Facebook private groups; 3) test if improvements in EAs' cancer risk knowledge and beliefs, digital and media literacy skills, accurate cancer prevention information, and family communication mediate impact of the social media campaign; and 4) explore whether the impact of the social media campaign differs according to: a) level of EAs' engagement with campaign, b) cancer risk factors, and c) biological sex of the participants (as required by NIH). The research is innovative because it tests a theory-based, multi-risk factor approach to cancer prevention with diverse EAs in rural counties, an under-studied population, in a very popular new media. Social media may reach EAs more than interventions through other community channels (e.g., clinics, schools, and workplaces) and for lower cost in the geographically-dispersed, underserved rural communities in the Mountain West. The overall impact is extremely high because it will aid rural EAs in making informed decisions that reduce cancer risk factors and prevent cancer later in life and help EAs critically evaluate and resist misinformation and marketing that promote cancer risk behaviors.
Study design
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- Randomized stepped-wedge with four cohorts
| Arm | Type | Receives |
|---|---|---|
| 4 Corners Rural Cancer Prevention | Experimental | Behavioral: 4 Corners Rural Health Cancer PreventionFour separate Facebook groups, which provide information via posts within the private groups about cancer risk factors (e.g. reducing alcohol consumption, tobacco use cessation, increasing physical activity), behavioral skills to reduce them, benefits of, social support for, and ways to reduce social/financial costs of cancer prevention, and advice from health care providers to decrease barriers. Posts will seek to improve self- and response-efficacy and perceived risk, and link cancer prevention to personal goals. |
Who may qualify
- Ages
- 18 to 26 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- Aged 18-26 years old
- Resides in a county coded as RUCC 4-9 in Arizona, Colorado, New Mexico, or Utah
- Able to speak and read English
- Has regular social media engagement
- Accepts screening call from study staff
Key exclusion criteria (7 listed)
- Participated in community engagement activities
- Cannot speak and read English
- Has low or no social media engagement
- Does not accept a screening call from study staff
- Does not consent to participate
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| 4 Corners Rural Health Cancer PreventionParticipants, aged 18-26, will join a private Facebook group to participate in the intervention. The group is not viewable to the public, including other Facebook users. Content that focuses on cancer prevention behaviors will be posted twice per day for up to 12 months. Each group will be hosted by a moderator who is responsible for managing the intervention goals and participants' engagement. | Behavioural | 4 Corners Rural Cancer Prevention |
Primary outcome
Physical Activity
Time frame: Baseline
Participants will self-report minutes per week of moderate to vigorous physical activity.
Physical Activity
Time frame: 3 months
Participants will self-report minutes per week of moderate to vigorous physical activity.
Physical Activity
Time frame: 12 months
Participants will self-report minutes per week of moderate to vigorous physical activity.
Physical Activity
Time frame: 24 months
Participants will self-report minutes per week of moderate to vigorous physical activity.
Diet
Time frame: Baseline
Participants will self-report intake per day of fruits, vegetables, whole grains/fiber, added sugars (from sugar-sweetened beverages), and red/processed meats.
Diet
Time frame: 3 months
Participants will self-report intake per day of fruits, vegetables, whole grains/fiber, added sugars (from sugar-sweetened beverages), and red/processed meats.
Diet
Time frame: 12 months
Participants will self-report intake per day of fruits, vegetables, whole grains/fiber, added sugars (from sugar-sweetened beverages), and red/processed meats.
Diet
Time frame: 24 months
Participants will self-report intake per day of fruits, vegetables, whole grains/fiber, added sugars (from sugar-sweetened beverages), and red/processed meats.
Nicotine Product Use
Time frame: Baseline
Participants will self-report tobacco/nicotine use in the past 30 days (every day, some days, not at all).
Nicotine Product Use
Time frame: 3 months
Participants will self-report tobacco/nicotine use in the past 30 days (every day, some days, not at all).
Nicotine Product Use
Time frame: 12 months
Participants will self-report tobacco/nicotine use in the past 30 days (every day, some days, not at all).
Nicotine Product Use
Time frame: 24 months
Participants will self-report tobacco/nicotine use in the past 30 days (every day, some days, not at all).
Alcohol Intake
Time frame: Baseline
Participants self-report consumption of number of alcoholic drinks in the past 30 days.
Alcohol Intake
Time frame: 3 months
Participants self-report consumption of number of alcoholic drinks in the past 30 days.
Alcohol Intake
Time frame: 12 months
Participants self-report consumption of number of alcoholic drinks in the past 30 days.
Alcohol Intake
Time frame: 24 months
Participants self-report consumption of number of alcoholic drinks in the past 30 days.
Uv Exposure
Time frame: Baseline
Participants will self-report number of sunburns.
Uv Exposure
Time frame: 3 months
Participants will self-report number of sunburns.
Uv Exposure
Time frame: 12 months
Participants will self-report number of sunburns.
Uv Exposure
Time frame: 24 months
Participants will self-report number of sunburns.
HPV Vaccination
Time frame: Baseline
Participants will self-report whether or not they have received one or more doses of the HPV vaccine.
HPV Vaccination
Time frame: 3 months
Participants will self-report whether or not they have received one or more doses of the HPV vaccine.
HPV Vaccination
Time frame: 12 months
Participants will self-report whether or not they have received one or more doses of the HPV vaccine.
HPV Vaccination
Time frame: 24 months
Participants will self-report whether or not they have received one or more doses of the HPV vaccine.
28 secondary outcomes
Physical Activity
Time frame: Baseline
Physical Activity
Time frame: 3 months
Physical Activity
Time frame: 12 months
Physical Activity
Time frame: 24 months
Diet
Time frame: Baseline
Diet
Time frame: 3 months
Diet
Time frame: 12 months
Diet
Time frame: 24 months
Nicotine Product Use
Time frame: Baseline
Nicotine Product Use
Time frame: 3 months
Nicotine Product Use
Time frame: 12 months
Nicotine Product Use
Time frame: 24 months
Nicotine Product Use
Time frame: Baseline
Nicotine Product Use
Time frame: 3 months
Nicotine Product Use
Time frame: 12 months
Nicotine Product Use
Time frame: 24 months
Alcohol Intake
Time frame: Baseline
Alcohol Intake
Time frame: 3 months
Alcohol Intake
Time frame: 12 months
Alcohol Intake
Time frame: 24 months
UV Exposure
Time frame: Baseline
UV Exposure
Time frame: 3 months
UV Exposure
Time frame: 12 months
UV Exposure
Time frame: 24 months
HPV Vaccination
Time frame: Baseline
HPV Vaccination
Time frame: 3 months
HPV Vaccination
Time frame: 12 months
HPV Vaccination
Time frame: 24 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Oct 2026.
- Derived from this study: PubMed 41505184Warner EL, Kinsey A, Walkosz BJ, Berteletti J, Nuss K, Small A, Woodall WG, Kepka D, Taren D, Skiba MB, Guest DD, Blair CK, Gordon JS, Wetter DW, Borrayo EA, Henry KL, Sussman AL, Buller DB. A Web-Based Cancer Prevention Intervention for Rural Emerging Adults: Mixed Methods Development and Pilot-Testing Study. J Med Internet Res. 2026 Jan 8;28:e80803. doi: 10.2196/80803.
- Derived from this study: PubMed 38386396Buller DB, Sussman AL, Thomson CA, Kepka D, Taren D, Henry KL, Warner EL, Walkosz BJ, Woodall WG, Nuss K, Blair CK, Guest DD, Borrayo EA, Gordon JS, Hatcher J, Wetter DW, Kinsey A, Jones CF, Yung AK, Christini K, Berteletti J, Torres JA, Barraza Perez EY, Small A. #4Corners4Health Social Media Cancer Prevention Campaign for Emerging Adults: Protocol for a Randomized Stepped-Wedge Trial. JMIR Res Protoc. 2024 Feb 22;13:e50392. doi: 10.2196/50392.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
David Buller, PhD principal investigator
Klein Buendel, Inc.
5 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing 4 Corners Rural Health Cancer Prevention in people with Cancer, run by Klein Buendel, Inc. at 5 sites in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 19 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 5 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Physical Activity (time frame: Baseline). The study lists 24 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05618158, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Oct 2026.