Clinical trials: Aged, 80 and Over
Sarcopenia, Aging
Reducing Falls With Progressive Resistance Training for the Oldest Old Adults With Reduced Muscle Strength
This study will investigate the effects of 12 months of high-intensity progressive resistance training compared with a control group on fall-rate in older adults with reduced muscle strength.
- Trial name
- ReFit (NCT05691166)
- Testing
- High-intensity progressive resistance training, Written physical activity guidance
- Where
- Norway
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Aged, 80 and Over
Predictors Associated With Maintaining Driving in Old Age
The goal of this observational study is to learn about predictors associated with maintaining driving in old age. The main questions it aims to answer are : which and how medical factors can influence stopping or maintaining…
- Trial name
- NCT05872490
- Testing
- Semi-structured interviews, Questionnaire
- Where
- 3 sites in France
- Volunteers
- 657 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Confusion, Inflammation
Confusion in the Elderly After Colon Surgery
A study will be conducted to determine if there is any cognitive benefit in elderly patients having open versus minimally invasive colon cancer surgery.
- Conditions
- Confusion, Inflammation, Acute Phase Reaction, Surgery
- Trial name
- NCT01623297
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- New York Hospital Queens
Aged
The Umeå High-Intensity Training Study
This randomized controlled trial will evaluate the effect of high-intensity training (HIT) in older sedentary people. Seventy older people, aged 65 and over, will be randomized to HIT or moderate-intensity continuous training…
- Trial name
- Umeå HIT (NCT03765385)
- Testing
- High-intensity training, Moderate-intensity continuous training
- Where
- Sweden
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Umeå University
Assessment, Self, Muscle Atrophy
Correlation of Muscle Ultrasound Measures (2D and 3D) With Biphotonic X-ray Absorptiometry in Oldest Old Patients.
The sarcopenia diagnosis is based on the muscle mass and on impaired physical performance. The emerging field of ultrasound assessment of muscle mass in older patients is based on 2d parameters with prediction equations for…
- Conditions
- Assessment, Self, Muscle Atrophy, Ultrasound Therapy; Complications, Aging
- Trial name
- DIASEM (NCT04753450)
- Testing
- No intervention
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Colorectal Neoplasms
Risk-adapted Screening in First-degree Relatives of Patients With Colorectal Cancer
BACKGROUND: First-degree relatives of patients with colorectal cancer are at increased risk for colorectal cancer as well. Nevertheless, participation in the German national screening program stagnates at 2-3 percent per year…
- Trial name
- FAMKOL (NCT01903395)
- Testing
- Nurse-led counselling
- Where
- 33 sites in Germany
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Pulmonary Disease, Chronic Obstructive
Blood Levels and Effects of GSK1325756 in Healthy Adult Volunteers Aged 40 to 80 Years Old
This study will invite two groups of volunteers to participate. The data from one group of volunteers will be used to find out how much study drug, known as GSK1325756, is in the blood after taking the drug twice in one day.
- Trial name
- NCT01267006
- Testing
- GSK1325756
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Gait Disorder
Cognitive Training and Dual-task Ability
The first goal of this study is to examine the extent to which the inclusion of dual-task practice to standard balance rehabilitation results in greater benefits to dual-task ability.
- Trial name
- NCT01895608
- Testing
- Balance rehabilitation + dual-tasking, Standard balance rehabilitation, Cognitive training (speed of processing)
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Hypertension, Elderly
Predictive Values of Blood Pressure and Arterial Stiffness in Institutionalized Very Aged Population
Introduction: High blood pressure especially systolic hypertension is a common condition in the elderly and is considered as a major determinant not only of cardiovascular (CV) morbidity and mortality, but also of several other…
- Conditions
- Hypertension, Elderly, Cardiovascular Mortality, Cognitive Impairment
- Trial name
- PARTAGE (NCT00901355)
- Where
- 6 sites in France, Italy
- Volunteers
- 1,130 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Frailty, Obesity
Slow Gait Speed as an Indicator of Overweight, Dynapenic Obesity and Sarcopenic Obesity in Elderly People in the Community
The goal of this observational study is to evaluate the relationship of gait speed with dynapenic or sarcopenic obesity in community-dwelling older people.
- Conditions
- Frailty, Obesity, Sarcopenia, Sarcopenic Obesity
- Trial name
- SGSF (NCT06413030)
- Testing
- 10 Meter Walk Test
- Where
- Chile
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- University of Americas - Chili
Healthy
Synbiotic Approach to Immunity and Metabolism in the Elderly Study
The aging process leads to a marked decline in immune function (immunosenescence), causing a significant reduction in immune response after vaccination or infections.
- Trial name
- SAIMES (NCT03168503)
- Testing
- LGG+Promitor™, Promitor™, LGG-PB12+Promitor™
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Roehampton
Mobility
Best Function of Range of Motion (cRCT)
Mobility is a crucial factor for independence and quality of life in older people. However, the majority of those in retirement homes are not physically active to maintain mobility and independence.
- Trial name
- bestform (NCT04207307)
- Testing
- Multimodal exercise program, Usual Care
- Where
- Germany
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Accidental Fall, Accident Prevention
Effect of Treadmill Perturbation Training on Falls
This parallel, randomized, controlled trial aims to quantify the effects of slip- and trip-perturbation training on fall rates collected over 12 months, compared to time-matched treadmill walking, among community-dwelling older…
- Trial name
- NCT04733222
- Testing
- Perturbation training, Treadmill walking
- Where
- Denmark
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Healthy
Does Motor Imagery Training Enhance Control of Movement in Older Adults?
The goal of this clinical trial is learn about motor imagery training (i.e. imagining a task) with healthy older adults. The main question this clinical trial aims to answer is: Will imagining a task improve control of force…
- Trial name
- NCT05669131
- Testing
- Motor imagery training
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Cognition, Dementia
Computerized Cognitive Intervention in the Oldest-Old
Little is known about preventive strategies with immediate public health impact for cognitive functioning in the oldest-old (OO).
- Trial name
- NCT03397498
- Testing
- CogniFit™, Control-games
- Where
- 2 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Aged, 80 and Over, Resistance Training
Resistance-type Exercise Training in the Older Population
Background: Aging is associated with muscle mass and strength loss and "oldest" old people (≥85 y) are at a far greater risk of developing sarcopenia.
- Trial name
- RETO (NCT04999501)
- Testing
- Prolonged resistance-type exercise training
- Where
- Chile
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Endothelial Dysfunction, Aging
Passive Mobilization and Vascular Function
With aging, vascular function (VF) declines. Inactivity and sedentary life style have been shown to contribute to the worsening of VF.
- Conditions
- Endothelial Dysfunction, Aging, Bed Rest
- Trial name
- NCT03087643
- Testing
- Passive mobilization - PM
- Where
- 3 sites in Italy
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Sedentary
Effects of Two Physical Exercise Protocols on Cognition and Physical Performances in Elderly Over 80 Years
The purpose of this study is to compare the effects of different trainings on cognition and physical performances in elderly over 80 years.
- Trial name
- NCT01983397
- Testing
- Multicomponent training, Resistance training
- Where
- Brazil
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Accidental Falls
A Feasibility Study of a Mobile Application Intervention to Promote Strength and Balance Exercises in Older People
This five arm feasibility study aims to promote self-management in strength and balance exercises among community-living older people.
- Trial name
- NCT02916849
- Testing
- Safe Step, OEP
- Where
- Sweden
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Umeå University
Volunteers
Effects of Mode of Contraction on Neuromuscular Fatigue
Aging is associated with multiple deteriorations of the neuromuscular system. Given the increase in life expectancy, the investigators can now distinguish old adults (>60 years old) who conserve their neuromuscular capacities…
- Trial name
- DYN-AGING (NCT04516538)
- Testing
- Mini Mental State Examination, 6 Minutes Walk Test, Timed up and go
- Where
- France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne