HealthyNCT05669131
Does Motor Imagery Training Enhance Control of Movement in Older Adults?
A study testing Motor imagery training in people with Healthy, run by University of British Columbia.
Trial summary
The goal of this clinical trial is learn about motor imagery training (i.e. imagining a task) with healthy older adults. The main question this clinical trial aims to answer is: Will imagining a task improve control of force during an elbow flexion muscle contraction in healthy older adults? Participants will… Read more about this study
- Who is it for?
- Ages 65 to 90 yearsHealthy volunteers can take part
- Conditions the study is for
- Healthy
- What is being tested?
- Motor imagery training
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- No sites listed yet
- Study dates
- Dec 2022to Aug 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 to 90 years
- All sexes
- Healthy volunteers accepted
- Older adult
Who may be able to join
- Healthy older adults aged 65 to 90 years old
Who cannot join
- have had an injury or orthopaedic surgery to the arm or shoulder in the prior 6 months
- are involved in high levels of upper-body strength training
- have history of training in fine motor tasks (i.e., musicians)
- have a history of MIT
- have systemic diseases and/or nerve damage affecting neuromuscular function
- have severe cognitive impairment
- are unable to read or speak English fluently
- are left hand dominant
Trial locations and contacts
No sites are listed yet.
About this study
Official title: Motor Imagery Training, Force Steadiness and Neural Drive
The goal of this clinical trial is learn about motor imagery training (i.e. imagining a task) with healthy older adults. The main question this clinical trial aims to answer is:
- Will imagining a task improve control of force during an elbow flexion muscle contraction in healthy older adults?
Participants will:
- Complete questionaries about general activity levels and ability to imagine tasks
- Perform either motor imagery training or watch a documentary
- Perform maximal and submaximal elbow flexion contractions
Researchers will compare the motor imagery training with the control group to see if control of force is improved in the motor imagery training group.
Read the detailed description
Motor imagery training could be beneficial in rehabilitative settings when participants are not physically capable of preforming a motor task or in injury prevention scenarios such as when multiple repetitions of a motor task should not be performed. If the effects of motor imagery training are favourable then they could have meaningful influence on the performance of steady movements in older adults who experience declines in force steadiness with age. Therefore, the first aim of this study will be to determine if one session of motor imagery training will influence corticospinal excitability in older adults and improve force steadiness during isometric elbow flexion contractions with the observed benefit being greater in females. The second aim of this study will be to determine if there is an associated change in oscillations in common synaptic input to motor neurons with a change in force steadiness.
- Conditions
- Healthy
- Being tested
- Motor imagery training
- Keywords
- Aged, Aged, 80 and over
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Motor imagery trainingOther
Participants imagine themselves through their own eyes performing submaximal elbow flexion contractions.
| Study group | Role | What they receive |
|---|---|---|
| Motor Imagery Training | Experimental | Participants will do motor imagery training in 5 minute blocks for a total of 20 minutes. Receives: Other: Motor imagery training |
| Control | No intervention | Participants will watch a documentary in 5 minute blocks for a total of 20 minutes. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Force steadiness
Measured as the the coefficient in variation of force
Measured: Within one session: Change from baseline (immediately before session) to 20 minutes after the session
Corticospinal excitability
Measured as the peak-to-peak amplitude of a motor evoked potential
Measured: Within one session: Change from baseline (immediately before session) to 20 minutes after the session
Common synaptic input
Estimated from motor unit discharge times.
Measured: Within one session: Change from baseline (immediately before session) to 20 minutes after the session
Secondary outcomes (1)
Maximal elbow flexion force
The total amount of force produced during a maximal contraction
Measured: Within one session: Change from baseline (immediately before session) to 20 minutes after the session
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Dec 2022
- Study startDec 2022 (estimated)
- Primary completionAug 2023 (estimated)
- Study completionAug 2023 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HealthyStudies of the same condition, open and under way.
- More trials run by University of British ColumbiaThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants will be randomly assigned to either the motor imagery training group or the control group.
- Masking
- None (open label)
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of British Columbia
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Jennifer Jakobi, University of British Columbia
- Investigators
- Jennifer Jakobi, PhD, Principal investigator, University of British Columbia- Okanagan
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05669131
- Sponsor's protocol ID
- MIT&ForceSteadiness
- Status last verified
- Dec 2022
- First submitted
- 29 Nov 2022
- Last updated
- 30 Dec 2022
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 30 Dec 2022. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Motor Imagery Training, Force Steadiness and Neural Drive
- ClinicalTrials.gov ID
- NCT05669131
- Acronym / sponsor ID
- MIT&ForceSteadiness
- Conditions
- Healthy
- Keywords
- Aged, Aged, 80 and over
- Study type
- Interventional
- Recruitment status
- Unknown status
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- University of British ColumbiaUniversity, hospital or other
- Study start
- Dec 2022 (estimated)
- Primary completion
- Aug 2023 (estimated)
- Study completion
- Aug 2023 (estimated)
- First posted
- 30 Dec 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is learn about motor imagery training (i.e. imagining a task) with healthy older adults. The main question this clinical trial aims to answer is:
- Will imagining a task improve control of force during an elbow flexion muscle contraction in healthy older adults?
Participants will:
- Complete questionaries about general activity levels and ability to imagine tasks
- Perform either motor imagery training or watch a documentary
- Perform maximal and submaximal elbow flexion contractions
Researchers will compare the motor imagery training with the control group to see if control of force is improved in the motor imagery training group.
Detailed description
Motor imagery training could be beneficial in rehabilitative settings when participants are not physically capable of preforming a motor task or in injury prevention scenarios such as when multiple repetitions of a motor task should not be performed. If the effects of motor imagery training are favourable then they could have meaningful influence on the performance of steady movements in older adults who experience declines in force steadiness with age. Therefore, the first aim of this study will be to determine if one session of motor imagery training will influence corticospinal excitability in older adults and improve force steadiness during isometric elbow flexion contractions with the observed benefit being greater in females. The second aim of this study will be to determine if there is an associated change in oscillations in common synaptic input to motor neurons with a change in force steadiness.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Participants will be randomly assigned to either the motor imagery training group or the control group.
| Arm | Type | Receives |
|---|---|---|
| Motor Imagery Training | Experimental | Other: Motor imagery trainingParticipants will do motor imagery training in 5 minute blocks for a total of 20 minutes. |
| Control | No intervention | –Participants will watch a documentary in 5 minute blocks for a total of 20 minutes. |
Who may qualify
- Ages
- 65 to 90 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Older adult
Key inclusion criteria (1 listed)
- Healthy older adults aged 65 to 90 years old
Key exclusion criteria (8 listed)
- have had an injury or orthopaedic surgery to the arm or shoulder in the prior 6 months
- are involved in high levels of upper-body strength training
- have history of training in fine motor tasks (i.e., musicians)
- have a history of MIT
- have systemic diseases and/or nerve damage affecting neuromuscular function
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Motor imagery trainingParticipants imagine themselves through their own eyes performing submaximal elbow flexion contractions. | Other | Motor Imagery Training |
Primary outcome
Force steadiness
Time frame: Within one session: Change from baseline (immediately before session) to 20 minutes after the session
Measured as the the coefficient in variation of force
Corticospinal excitability
Time frame: Within one session: Change from baseline (immediately before session) to 20 minutes after the session
Measured as the peak-to-peak amplitude of a motor evoked potential
Common synaptic input
Time frame: Within one session: Change from baseline (immediately before session) to 20 minutes after the session
Estimated from motor unit discharge times.
1 secondary outcome
Maximal elbow flexion force
Time frame: Within one session: Change from baseline (immediately before session) to 20 minutes after the session
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Dec 2022.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Jennifer Jakobi, PhD principal investigator
University of British Columbia- Okanagan
Questions about this trial
What is this clinical trial studying?
A study testing Motor imagery training in people with Healthy, run by University of British Columbia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 30 Dec 2022. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Jennifer Jakobi, PhD (250-807-9884, jennifer.jakobi@ubc.ca), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Force steadiness (time frame: Within one session: Change from baseline (immediately before session) to 20 minutes after the session). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Dec 2022.