Clinical trials: Adolescent and Young Adult Cancer
Pediatric Cancer, Adolescent and Young Adult Cancer
Improving Communication Between AYA Oncology Patients and Clinicians: A Patient-Centered Intervention
The overarching goal is to develop and demonstrate proof-of-concept of ReSPECT (Reproductive and Sexual Health Patient Education and Communication Tool), a multi-modal communication intervention to improve adolescent and young…
- Trial name
- NCT06982066
- Testing
- ReSPECT
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Connecticut Children's Medical Center
Cancer, Pediatric Cancer
Digital Art Therapy for Young Cancer Survivors
This is a single-site, single-arm, interventional study assessing the feasibility of the ARTCan Therapy Application (App) and whether it is an acceptable means of administering art therapy to young adult cancer survivors.
- Conditions
- Cancer, Pediatric Cancer, Pediatric Malignancies, Pediatric Sarcoma of Soft Tissue
- Trial name
- NCT06789666
- Testing
- ARTCan App
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cancer, Cancer Survivorship
AYA Cancer Transitions Program
This is a single-arm, minimal-risk, interventional behavioral clinical trial embedding structured transition support for adolescent and young adult (AYA) survivors of pediatric cancer transitioning into adult-focused survivorship…
- Conditions
- Cancer, Cancer Survivorship, Adolescent and Young Adult Cancer Survivors, Transitions of Care
- Trial name
- NCT07865013
- Testing
- Transitions Program
- Volunteers
- 100 people
- Sponsor
- University of Kansas Medical Center
Financial Toxicity, Cancer
Implementing Stepped Financial and Legal Navigation to Mitigate Financial Toxicity in Adolescent and Young Adult Cancer Patients Oncology Financial and Legal Navigation (OFLN)
The overall objective of this study is to test the effectiveness and implementability of stepped Oncology Financial and Legal Navigation (OFLN) in a noninferiority randomized controlled trial (RCT) using a hybrid type 1…
- Conditions
- Financial Toxicity, Cancer, Adolescent, Young Adult Cancer Survivors
- Trial name
- OFLN (NCT07849699)
- Testing
- Oncology Financial and Legal Navigation (OFLN) Stepped: Low Intensity, Oncology Financial and Legal Navigation (OFLN) Standard, Oncology Financial and Legal Navigation (OFLN) Stepped: High-Intensity
- Where
- United States
- Volunteers
- 294 people
- Sponsor
- University of Louisville
Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma
CAYA Cancer Retrospective Cohort Study
Despite advances in cancer treatment, significant disparities in outcomes persist between high-income countries (HICs) and low-and middle-income countries (LMICs).
- Conditions
- Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Young Adult Cancer, Adolescent Cancer
- Trial name
- NCT07246213
- Testing
- Retrospective Medical Record Review
- Where
- 7 sites in Armenia, Egypt and 4 more
- Volunteers
- 18,000 people
- Sponsor
- Resonance, Inc.
Wellness Program, Cancer Survivorship
Brief Meaning-making for Young Adult Cancer Survivors
The goal of this feasibility study is to learn if a brief meaning-making wellness intervention based on Viktor Frankl's Existential Psychology works to improve fatigue levels in Young Adult Cancer Survivors (YACS) who have…
- Conditions
- Wellness Program, Cancer Survivorship, Adolescent and Young Adult Cancer Survivors
- Trial name
- NCT07836075
- Testing
- Meaning-making
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Cancer, Young Adult Cancer
Comprehensive Care for AYA: Needs Assessment Survey
The goal of this observational study is to assess gaps in education about exercise, sexual health, fertility, survivorship, financial issues, interpersonal relationships, and clinical trial participation among adolescents and…
- Conditions
- Cancer, Young Adult Cancer, Adolescent Cancer
- Trial name
- NCT07196241
- Testing
- Survey using a questionnaire.
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Wake Forest University Health Sciences
Adolescents and Young Adults With Cancer
A Study of Questionnaires in Adolescents and Young Adults With Cancer
The purpose of this study is to evaluate a questionnaire called PRO-AYA: Patient-Reported Outcomes for Adolescents and Young Adults.
- Trial name
- NCT07212166
- Testing
- Patient-Reported Outcome Surveys, Spanish version of PRO-AYA and the cognitive interview
- Where
- 7 sites in United States
- Volunteers
- 120 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Chatbot, Large Language Model
Effects of a Large Language Model-Driven Chatbot on Reproductive Concerns After Cancer
Reproductive health has emerged as a critical yet overlooked concern among Adolescent and Young Adult (AYA) cancer survivors, given their compromised potential for biological parenthood in prime childbearing years.
- Conditions
- Chatbot, Large Language Model, Adolescent and Young Adult Cancer Survivors, Reproductive Health
- Trial name
- NCT07741266
- Testing
- Chatbot, Electronic brochure
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Cancer Survivorship, Family Planning
Family Building Decision Support for Female Adolescent and Young Adult Cancer Survivors
This study aims to develop and pilot-test a nurse navigator-delivered behavioral program to support female adolescent and young adult (AYA) cancer survivors in making informed, values-driven family-building decisions after…
- Conditions
- Cancer Survivorship, Family Planning, Adolescent and Young Adult Cancer
- Trial name
- NCT07471685
- Testing
- Nurse Navigator-Delivered Family Building Decision Support, Survivorship Education
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Duke University
Adolescent Cancer, Young Adult Cancer
Feasibility of Expressive Writing for Body Image Distress and Anxiety Among Adolescent and Young Adult Cancer Survivors
Each year, about 89,500 adolescents and young adults (AYAs; 15-39 years old) are diagnosed with cancer and up to 60% experience body image (BI) distress.
- Conditions
- Adolescent Cancer, Young Adult Cancer, Body Image
- Trial name
- NCT06046014
- Testing
- BI Focused writing, Control
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan Rogel Cancer Center
Cancer, Adolescent Cancer
Life at 100.4: An Immersive Social Virtual Reality (VR) Education Tool for Adolescent and Young Adult Cancer Patients and Caregivers
The purpose of this study is to design and Beta test the Life at 100.4, an immersive social virtual reality education tool, with an anticipated 5 patient-caregiver-provider triads.Patients at Yale Pediatric Hematology and…
- Conditions
- Cancer, Adolescent Cancer, Young Adult Cancer
- Trial name
- NCT07224204
- Testing
- Life at 100.4
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Yale University
Adolescent and Young Adult (AYA) Cancer Survivors
AYA STEPS RCT: AYA Self-Management Via Texting, Education & Plans for Survivors
The proposed project will leverage two programs of research at UPenn and CHOP that are delivering technology-based interventions to adolescent and young adult (AYA) cancer survivors.
- Trial name
- NCT03363711
- Testing
- AYA STEPS
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Depression, Cancer
Optimizing the AYA Survivors' Coping and Emotional Needs Toolkit
Our team has developed a digital intervention that aims to help adolescent and young adult cancer survivors (AYAs) manage symptoms of depression.
- Conditions
- Depression, Cancer, Adolescent, Young Adult
- Trial name
- ASCENT (NCT07173205)
- Testing
- AYA Survivors Coping and Emotional Needs Toolkit (ASCENT)
- Where
- 2 sites in United States
- Volunteers
- 208 people
- Sponsor
- East Carolina University
Financial Toxicity Related to Cancer Diagnosis and Tretment in Adolescents and Young Adults
FINancial Toxicity and CAncer REcovery in YOUNG Adults
The FINCARE-Young study aims to investigate the extent and development of financial toxicity in adolescents and young adults with cancer.
- Trial name
- FINCARE-Young (NCT07314801)
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- University Medical Center Goettingen
Adolescent and Young Adult Cancer Patient
Adolescents and Young Adults (AYAs) With Advanced Cancer
This study aims to develop and test the feasibility and acceptability of a psychosocial symptom management intervention designed to meet the unique needs of Adolescents and Young Adults (AYAs) with advanced cancer.
- Trial name
- NCT05593016
- Testing
- Symptom Management for Improved Physical and Emotional Wellbeing (SMILE), Education Control Arm
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Duke University
Cancer, Adolescent Behavior
Impact of Sick Peer Relation on Adaptation to Disease and on Treatment of Cancer-suffering Adolescents & Young Adults
Adolescents and young adults (AYA) with cancer have to deal with a relatively segmented organization of care between pediatric and adult medicine structures in France.
- Conditions
- Cancer, Adolescent Behavior, Young Adult
- Trial name
- PAIRS-AJA (NCT03964116)
- Testing
- Questionnaires set all 3 months
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Institut Curie
Depression, Cancer
Evaluating Procedures for a Study of the AYA Survivors Coping and Emotional Needs Toolkit
The investigators developed a digital intervention that aims to help adolescent and young adult cancer survivors (AYAs) manage symptoms of depression.
- Conditions
- Depression, Cancer, Adolescent, Young Adult
- Trial name
- ASCENT (NCT06420193)
- Testing
- AYA Survivors Coping and Emotional Needs Toolkit (ASCENT)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- East Carolina University
Adolescent and Young Adult Cancers
CyberCycling to Reduce Therapeutic Side Effects and Improve Quality of Life in AYA Cancers
Only a few clinical trials evaluating the potential benefits of exercise have been conducted in adolescents and young adults (AYA) with cancer and, no prior studies have evaluated the potential effects of 'cybercycling'…
- Trial name
- NCT02916472
- Testing
- CyberCycling, Stretching, Resistance Bands
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Case Comprehensive Cancer Center
Adolescent, Young Adult
Utilizing Novel Information Technology to Promote Exercise and Well-Being in Adolescents and Young Adults With Cancer
Adolescents and young adults (AYAs) with cancer have many needs for supportive care that differ from younger and older patients.This includes age-appropriate psychological support for management of distress, as well as supports…
- Conditions
- Adolescent, Young Adult, Cancer, Physical Activity
- Trial name
- AYA-UNITE (NCT03778658)
- Testing
- Physical Activity Intervention
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Milton S. Hershey Medical Center