Clinical trials: Adolescent Idiopathic Scoliosis
Adolescent Idiopathic Scoliosis (AIS)
Enhancing the Therapeutic Effect of Bracing for Adolescent Idiopathic Scoliosis With a Hybrid Bracing Protocol
This is a prospective randomized controlled trial investigating the therapeutic effect of the Hybrid Bracing Protocol (HyBP) over the Conventional Brace in enhancing In-brace Correction (IBC) for adolescent idiopathic…
- Trial name
- NCT07045337
- Testing
- Hybrid Bracing, Conventional fulltime Underarm Bracing
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Chinese University of Hong Kong
Scoliosis Idiopathic Adolescent, Core Stabilization Exercise
Effectiveness of a Horse Riding Simulator in Adolescents With Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity associated with impaired respiratory muscle strength, balance, postural control, body image, and health-related quality of life.
- Conditions
- Scoliosis Idiopathic Adolescent, Core Stabilization Exercise, Horseback Riding, Postural Balance
- Trial name
- NCT07758712
- Testing
- Horse Riding Simulator, Core Stabilization Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bezmialem Vakif University
Adolescent Idiopathic Scoliosis (AIS)
Intravenous Dexamethasone for ESP Block Analgesia in Children Undergoing Idiopathic Scoliosis Surgery
This randomized, double-blind, placebo-controlled study will evaluate the effect of intravenous dexamethasone on postoperative analgesia in children and adolescents undergoing surgery for idiopathic scoliosis with bilateral…
- Trial name
- NCT07890220
- Testing
- Dexamethasone (0.1 mg/kg), Dexamethasone (0.2 mg/kg)
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
ASD, Scoliosis Idiopathic Adolescent
Quality of Life, Psychosocial Burden, and Structural-functional Status in Adults With Spinal Deformity.
This study examines which factors influence quality of life in adults with a spinal deformity. It looks at imaging findings together with pain, daily functioning, psychosocial factors, and frailty to support more person-centred…
- Conditions
- ASD, Scoliosis Idiopathic Adolescent, Scoliosis Idiopathic Adolescent Treatment
- Trial name
- ASD-QoL (NCT07749534)
- Testing
- first corrective surgery, Reoperation
- Where
- Belgium
- Volunteers
- 320 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Adolescent, Scoliosis
Sleep Quality in Adolescents With Idiopathic Scoliosis
This controlled cross-sectional observational study aims to compare sleep quality between adolescents with idiopathic scoliosis and age- and sex-similar healthy controls.
- Conditions
- Adolescent, Scoliosis, Adolescent Idiopathic Scoliosis (AIS)
- Trial name
- AIS-SLEEP (NCT07767591)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Scoliosis Idiopathic Adolescent
The Effect of Dexamethasone Administration Route and Local Anesthetic Concentration on Pain, Inflammatory Response, and Neuromonitoring in Children Undergoing Scoliosis Correction
Scoliosis correction surgery in children is a complex procedure with significant risks, including postoperative pain, inflammatory response, and potential neurological complications.
- Trial name
- NCT06789029
- Testing
- perineural Dexamethasone, intravenous Dexamethasone
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Idiopathic Scoliosis, Adolescent Idiopathic Scoliosis (AIS)
Real-World Effectiveness of Conservative Treatment in Idiopathic Scoliosis
This retrospective observational study aims to assess the real-world effectiveness of conservative treatment (bracing and specific exercises) in patients with idiopathic scoliosis treated with an Evidence-Based Personalised…
- Conditions
- Idiopathic Scoliosis, Adolescent Idiopathic Scoliosis (AIS), Juvenile Idiopathic Scoliosis
- Trial name
- NCT07873554
- Testing
- Brace, Specific exercises (SEAS)
- Where
- Italy
- Volunteers
- 30,000 people
- Sponsor
- Istituto Scientifico Italiano Colonna Vertebrale
Adolescent Idiopathic Scoliosis, Postoperative Pain, Acute
The Use of a Comfort Tote to Improve Recovery in Pediatric and Adolescent Patients After Surgery
The goal of this clinical trial is to learn if the use of Comfort Tote can treat pain and anxiety in adolescents with idiopathic scoliosis undergoing posterior spinal fusion. The study aims to answer two questions: 1.
- Conditions
- Adolescent Idiopathic Scoliosis, Postoperative Pain, Acute, Postoperative Nausea and Vomiting, Anxiety
- Trial name
- NCT07632833
- Testing
- The Therapeutic Comfort Tote, The Modified Comfort Tote
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Adolescent Idiopathic Scoliosis
Immediate Effects of Self-Corrective Training in Adolescent Idiopathic Scoliosis: A Nested Study
This nested study was conducted within a broader adolescent idiopathic scoliosis research protocol approved under IRB UW24-747. It evaluated immediate within-session changes in bilateral muscle-activation asymmetry and posterior…
- Trial name
- NCT07194564
- Testing
- Fixed-Sequence Exercise and Self-Corrective Posture Training
- Where
- Hong Kong
- Volunteers
- 36 people
- Sponsor
- The University of Hong Kong
Adolescent Idiopathic Scoliosis, Postural Balance
Feedback-Based Balance Training for Adolescents With Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is the most common form of scoliosis occurring during the growth period and is associated with significant alterations in postural balance compared with healthy peers.
- Trial name
- NCT07430098
- Testing
- HUBER® 360 Balance Training, Home-Based Balance Exercise Program, Individualized Conservative Scoliosis Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ankara Etlik City Hospital
Spinal Fusion, Adolescent Idiopathic Scoliosis
Low Dose Dexmedetomidine as a Postoperative Pain Adjunct
This randomized controlled trial examines whether the addition of a low-dose dexmedetomidine infusion to our current multimodal pain management plan decreases narcotic consumption and reduces side effects in adolescent patients…
- Trial name
- NCT06067893
- Testing
- Dexmedetomidine, Normal Saline
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Nichole Doyle
Adolescent Idiopathic Scoliosis (AIS)
Validation of the Clinical Decision Support Systems (CDSS) Developed in the EU Horizon PREPARE Project in the Rehabilitative Treatment of Idiopathic Scoliosis
The study aims to validate both the predictive capacity and the clinical usability of the Clinical Decision Support System (CDSS) developed within the PREPARE project (European Union Grant Agreement 101080288 PREPARE…
- Trial name
- PREPARE (NCT07379593)
- Testing
- CDSS simulation, Focus group - clinicians, Focus group - patients
- Where
- Italy
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Istituto Scientifico Italiano Colonna Vertebrale
Adolescent Idiopathic Scoliosis (AIS)
Hypnosis for Pain and Nausea Reduction in Scoliosis Surgery: An Interventional Study
This study evaluates whether preoperative hypnosis can reduce postoperative pain, nausea, and opioid use in adolescents undergoing scoliosis surgery. Participants aged 12-18 years will receive hypnosis training before surgery.
- Trial name
- HYP-SCOL (NCT07854951)
- Testing
- Hypnosis
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- St. Olavs Hospital
Fracture, Scoliosis Idiopathic Adolescent
Opioid Analgesia Impacts on Neurological Development
Background: Pain in childhood - whether from injuries like fractures or long-term conditions like scoliosis - is often treated with opioid medicines. These drugs are effective for pain relief.
- Conditions
- Fracture, Scoliosis Idiopathic Adolescent, Traumatic Injury, Adolescent
- Trial name
- OPAL (NCT07855952)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Nottingham
Scoliosis Idiopathic Adolescent, Cyberchondria
Cyberchondria in Adolescents With Idiopathic Scoliosis
Scoliosis is a three-dimensional torsional deformity of the spine and trunk characterized by alignment abnormalities in the coronal plane, the presence of axial rotation in the horizontal plane, and abnormalities in the normal…
- Trial name
- NCT07481071
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Adolescent Idiopathic Scoliosis
Diaphragm Mobilization in Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity that can affect posture, trunk movement, and respiratory function.
- Trial name
- NCT07482748
- Testing
- Diaphragm Mobilization, Schroth Best Practice Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Marmara University
Adolescent Idiopathic Scoliosis (AIS)
Relationship Between Spinopelvic Parameters and Plantar Pressure in Adolescents With Lenke Type I and V Scoliosis
Adolescent idiopathic scoliosis (AIS) affects the alignment of the spine and body posture, which can influence balance and the way body weight is distributed through the feet.
- Trial name
- AIS-PLANTAR (NCT07810140)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Aslıhan içer
Adolescent Idiopathic Scoliosis
Investigation of Muscle Activity With sEMG, Surface Topography and Radiographic Changes of Paraspinal Muscles in Individuals With Adolescent Idiopathic Scoliosis.
The aim of this study is to examine paraspinal muscle activity, body surface topography, posture, and radiographic characteristics in adolescents with idiopathic scoliosis.
- Trial name
- NCT07804836
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Adolescent Idiopathic Scoliosis (AIS)
Supervised vs. Home Schroth Exercise in AIS
This study aims to compare the effectiveness of supervised Schroth exercises versus a home-based exercise program in adolescents with Adolescent Idiopathic Scoliosis (AIS).
- Trial name
- NCT07779070
- Testing
- Supervised Schroth Exercise, Home-Based Schroth Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Bitlis Eren University
Scoliosis Idiopathic, Scoliosis Idiopathic Adolescent
Evaluation of Safety of Complex Pedicle Screw Trajectories Using Patient-Specific Guides (MySpine, Medacta)
This retrospective, single-center observational study evaluates the clinical safety and neurophysiological performance of patient-specific MySpine guides (Medacta International) for pedicle screw placement in patients undergoing…
- Conditions
- Scoliosis Idiopathic, Scoliosis Idiopathic Adolescent, Scoliosis Associated With Other Conditions, Scoliosis Idiopathic Adolescent Treatment
- Trial name
- Red Screws (NCT07790068)
- Testing
- Patient-Specific Guides to pedicle screws placement (MySpine, Medacta)
- Where
- Italy
- Volunteers
- 130 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio