Clinical trials: Adaptive Support Ventilation
Central Sleep Apnea, Heart Failure
French Cohort Study of Chronic Heart Failure Patients With Central Sleep Apnoea Eligible for Adaptive Servo-Ventilation (PaceWave, AutoSet CS, AirCurve 10CS): Predictive Factors of Poor Compliance (FACE)
The purpose of this study is to determine the predictive factors of poor compliance to sleep disordered breathing therapy in chronic heart failure patients treated for central sleep apnea.
- Trial name
- FACE (NCT02356367)
- Testing
- telemonitoring
- Where
- 3 sites in France
- Sponsor
- ResMed
Sleep Apnea Syndromes
Sleep Disordered Breathing and Chronic Pain
The purpose of this study is to evaluate positive pressure in patients with chronic pain taking opioid medications who have sleep disordered breathing.
- Trial name
- NCT01457014
- Testing
- servo ventilation auto, Continuous positive airway pressure, servo ventilation manual
- Where
- 4 sites in United States
- Volunteers
- 88 people
- Sponsor
- Philips Respironics
Acute Respiratory Distress Syndrome
Adaptive Support Ventilation in Acute Respiratory Distress Syndrome
The purpose of this protocol is to compare standard of care lung protective ventilation settings with an automated ventilator setting, called Adaptive Support Ventilation (ASV), in patients with acute respiratory distress…
- Trial name
- ARDS (NCT03715751)
- Testing
- ASV, Lung Protective Ventilation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Beth Israel Deaconess Medical Center
Apnea, Hypoxia
Effects of Automated Adjustment of Inspired Oxygen With Combined Adaptive Mechanical Backup Ventilation as Compared to Automated Oxygen Adjustment Alone in Preterm Infants With Intermittent Hypoxemic Events During Non-invasive Ventilatory Support
In this 2-phase cross-over study the investigators test the hypothesis that automated adjustment of the inspired oxygen with the combined use of synchronized noninvasive SpO2-sensitive and apnea-sensitive backup-ventilation…
- Trial name
- NCT02774408
- Testing
- Saturation sensitive backup ventilation
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Chronic Heart Failure
Adaptive Servo-ventilation Monitoring Study
Sleep disordered breathing is very common in patients with chronic heart failure with reported prevalence rates of 50-75%. Adaptive Servo-Ventilation (ASV) can be used to treat sleep apnea in these patients.
- Trial name
- NCT02133859
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- ResMed
Pulmonary Disease, Chronic Obstructive
Adaptive Support Ventilation in the Weaning of COPD
Adaptive support ventilation (ASV) is a closed loop ventilation mode that can act both as pressure support (PSV) and pressure controlled (PCV) ventilation.
- Trial name
- NCT00969605
- Testing
- Comparison of two different modes for weaning from mechanical ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people
- Sponsor
- Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital
Chronic Heart Failure, Sleep Apnea
The Effect of Adaptive Servo Ventilation and Oxygen Therapy in Central Sleep Apnea Patients
The aim of this study is to compare the effects of Adaptive Servo Ventilation (Bipap® auto SV Advanced) and oxygen therapy in chronic heart failure patients complicated with central sleep apnea.
- Trial name
- NCT01187823
- Testing
- Adaptive servo ventilation, Nocturnal oxygen
- Where
- Japan
- Volunteers
- 43 people
- Sponsor
- Kyoto University, Graduate School of Medicine
Heart Failure With Normal Ejection Fraction, Sleep Apnea
Adherence to ASV Therapy in Heart Failure With Preserved Ejection Fraction Feasibility Study
This study is designed to demonstrate feasibility of study conduct and that acceptable adherence to adaptive servo-ventilation (ASV) therapy can be achieved in recently hospitalized HFpEF patients with moderate to severe sleep…
- Trial name
- CAT-PEF (NCT03195660)
- Testing
- ASV Therapy
- Where
- 4 sites in United States, Germany
- Volunteers
- 6 people
- Sponsor
- ResMed
Central Sleep Apnea, Heart Failure With Preserved Ejection Fraction
Quality of Sleep of Patients With Predominant Central Sleep Apnea Syndrome(SAS) Whose EF > 45% Treated by ASV
The main goal of this French multicenter observational cohort study is to prospectively collect data assessing the impact of the Adaptative Servo-Ventilation treatment on the quality of sleep of patients with central or combined…
- Trial name
- FACIL-VAA (NCT02835638)
- Testing
- Adaptative Servo Ventilation
- Where
- 28 sites in France
- Volunteers
- 520 people
- Sponsor
- Société Française de Recherche et de Médecine du Sommeil
Central Sleep Apnea, Complex Sleep Apnea
Registry on the Treatment of Central and Complex Sleep-Disordered Breathing With Adaptive Servo-Ventilation
Phase 1: The European ASV Registry (short name) will investigate the use of Adaptive Servo-Ventilation in non-heart failure conditions.
- Conditions
- Central Sleep Apnea, Complex Sleep Apnea, Obstructive Sleep Apnea, Mixed Sleep Apnea
- Trial name
- READ-ASV (NCT03032029)
- Testing
- Adaptive Servo-Ventilation
- Where
- 29 sites in Denmark, France and 4 more
- Volunteers
- 847 people
- Sponsor
- ResMed
Mechanical Ventilation
Ventilation With ASV Mode in Children
ASV mode of ventilation is an automatic mode with closed-loop control used for mechanical invasive ventilation in intubated patients. It has been studied in adult patients but not in children.
- Trial name
- NCT03930147
- Testing
- ASV ventilation
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Lausanne Hospitals
Snake Envenomation, Invasive Mechanical Ventilation
A Study to Compare Adaptive Support Ventilation vs. Volume Controlled Ventilation for Management of Respiratory Failure in Patients With Neuroparalytic Snake Envenomation
Neuroparalytic snake envenomation results in severe muscle weakness and respiratory failure. Treatment requires administration of anti-snake venom and supportive care in the form of invasive mechanical ventilation.
- Conditions
- Snake Envenomation, Invasive Mechanical Ventilation, Adaptive Support Ventilation
- Trial name
- ASV vs VCV in (NCT02877498)
- Testing
- Adaptive support ventilation, Volume controlled ventilation
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Chronic Heart Failure and, Complex Sleep Apnea Syndrome
Adaptive Servo-Ventilation in "Real Life" Conditions : the OTRLASV Study
Adaptive Servo-Ventilation (ASV) treatment is routinely prescribed in France. In order to be reimbursed according to the French Social Security rules, the patient treated with an ASV needs to be examined each year.
- Conditions
- Chronic Heart Failure and, Complex Sleep Apnea Syndrome, Obstructive Sleep Apnea Syndrome and, Idiopathic Central Sleep Apnea Syndrome
- Trial name
- OTRLASV (NCT02429986)
- Testing
- Adaptive Servo-Ventilation
- Where
- 5 sites in France
- Volunteers
- 214 people
- Sponsor
- University Hospital, Montpellier
Acute Exacerbation of COPD
Non Invasive Ventilation With NAVA vs ASV for AECOPD
Non invasive ventilation is the standard of care in managing patients with exacerbation of chronic obstructive pulmonary disease.
- Trial name
- NCT04414891
- Testing
- Non invasive ventilation
- Where
- India
- Volunteers
- 76 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Acute Myocardial Infarction, Sleep Apnea
ASV for Sleep Apnea After Myocardial Infarction
The aim of this randomized controlled trial is to test the effect of 12 weeks Adaptive Servo-Ventilation (ASV) therapy (additionally to optimal medical management of myocardial infarction) on myocardial salvage (MSI=myocardial…
- Trial name
- TEAM-ASV-I (NCT02093377)
- Testing
- Adaptive servo-ventilation
- Where
- 5 sites in Germany
- Volunteers
- 79 people
- Sponsor
- University Hospital Regensburg
Central Sleep Apnea, ASV
Interface Selection for Adaptive Servo Ventilation
The purpose of this study is to compare the effects of nasal and oronasal interfaces during ASV treatment on sleep efficiency and sleep architecture.
- Trial name
- NCT02919930
- Testing
- Switch from oronasal to nasal mask during ASV treatment, Switch from nasal to oronasal mask during ASV treatment
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Insomnia, Insomnia (Moderate)
ASV Therapy for Insomnia
This will be a single center, prospective study designed to evaluate the effect of adaptive servo ventilation therapy on insomnia severity among patients with moderate to severe chronic insomnia.
- Trial name
- NCT07011966
- Testing
- ASV therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- ResMed
Ventilator Weaning
Comparative Study of Duration of Respiratory Weaning Between Adaptive Support Ventilation and Succession of Controlled Ventilation Then Spontaneous Ventilation for Patients After Surgery
This is a comparative study of duration of respiratory weaning between adaptive support ventilation and succession of controlled ventilation then spontaneous ventilation for patients after surgery.
- Trial name
- NCT00313326
- Testing
- Adaptative Support Ventilation
- Where
- France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Clermont-Ferrand
Heart Diseases, Sleep Apnea, Central
Comparison of CPAP With SOMNOventCR in Patients With Underlying Heart Disease, Combined OSA and CSR
In patients with underlying heart diseases like hypertensive heart disease, coronary heart disease or dilative cardiomyopathy obstructive sleep-apnea, central sleep-apnea and Cheyne-Stokes-respiration are common finding in…
- Conditions
- Heart Diseases, Sleep Apnea, Central, Sleep Apnea, Obstructive
- Trial name
- VCR (NCT00811668)
- Testing
- CPAP before SOMNOVentCR, SOMNOventCR before CPAP
- Volunteers
- 40 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
ARDS (Acute Respiratory Distress Syndrome)
The Variable Ventilation Trial (Part A)
The goal of this clinical trial is to learn if a breathing machine (ventilator) method called "variable ventilation" can help protect the lungs of adult patients with acute respiratory distress syndrome (ARDS) who need help…
- Trial name
- VV (A) (NCT07791225)
- Testing
- Variable Ventilation, Conventional Ventilation
- Where
- 5 sites in United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital