Clinical trials: Adaptation
Physical Fitness
BPIT 5-Week Multi-Site Study: Movement Efficiency, Mobility & Neuromuscular Adaptation
This prospective, multi-site, single-arm interventional study evaluates the 5-Line Principle of Balanced Progressive Intensity Training (BPIT) over 5 weeks in healthy adults aged 18-65 years.
- Trial name
- BPIT_5LINE_369 (NCT07256717)
- Testing
- Balanced Progressive Intensity Training (BPIT) 5-Line Method
- Where
- 10 sites in United States, India
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc.
Active Aging Individuals Aged 65 and Over, Aging
Italian Validation of the dNA Scale and Its Correlation With Neurocognitive Variables
The goal of this experimental multicentric intervention study is to validate, in Italian, the dynamic Neurocognitive Adaptation (dNA) Scale, which has already been validated in English, among a healthy elderly population (aged 65…
- Conditions
- Active Aging Individuals Aged 65 and Over, Aging, Mild Cognitive Impairment (MCI), Dementia
- Trial name
- NCT07533084
- Where
- 8 sites in Italy
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Mild Cognitive Impairment, Cognitive Dysfunction
Effects of a Computerized Cognitive Stimulation Intervention Adapted to the Level of Cognitive Reserve
Normal ageing presents subtle cognitive changes that can be detected before meeting the criteria for Mild cognitive impairment (MCI).
- Trial name
- NCT06279325
- Testing
- Computerized cognitive stimulation program, Face-to-face training-explanatory session
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Cardiovascular Diseases
Impact of Statin Therapy on Adaptations to Aerobic Exercise
The purpose of this study is to determine how different doses of a statin affect muscle health and exercise.
- Trial name
- NCT03360916
- Testing
- Lipitor 20Mg Tablet, Lipitor 80Mg Tablet, Exercise Program
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Parkinson Disease, Freezing of Gait
Motor Adaptation to Split-Belt Treadmill in Parkinson's Disease
Freezing of Gait (FOG) is a disabling symptom common in advanced Parkinson's Disease. FOG is an independent contributor to fall risk and is only partially relieved by medication.
- Trial name
- NCT03725215
- Testing
- Split-Belt Treadmill Training
- Where
- 2 sites in Belgium, Germany
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Premature, Infant Development
The Turkish Version of the Affordances in the Home Environment for Motor Development-Infant Scale (AHEMD-IS)
The Affordances in the Home Environment for Motor Development-Infant Scale (AHEMD-IS) is an instrument that assesses the quality and quantity of motor development opportunities available in the home for infants aged 3 to 18…
- Conditions
- Premature, Infant Development, Environmental Exposure
- Trial name
- AHEMD-IS (NCT05210959)
- Testing
- The Affordances in the Home Environment for Motor Development-Infant Scale (AHEMD-IS)
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Gazi University
Healthy
Impact of Stress and Sleep Management on Emergency Professionals
The investigators hypothesize that a recovery management program could have an impact on emergency nurses and physicians by improving their sleep and reducing their psychological and physiological responses when dealing with…
- Trial name
- REST (NCT05251246)
- Testing
- recovery management program
- Where
- France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Cigarette Smoking
Smoking, Stress, HIV and Mobile Technology
The present investigation aims to address disparities in cigarette use outcomes among Black/African American adults with HIV. The specific aims of this study are: (1) To modify a recently developed, culturally adapted, mobile…
- Trial name
- NCT05709002
- Testing
- MASP+, Control
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Houston
Inflammatory Arthritis
Inflammatory Arthritis and Difficulty at Work
Despite biologic drugs and improvements of inflammatory arthritis (IA) treatment, many patients with inflammatory arthritis still face increased absenteeism, reduced at-work productivity and report difficulties working and having…
- Trial name
- RENOIR (NCT04015960)
- Testing
- no intervention
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Lorraine
Youth, Physical Activity
Turkish Translation of Physical Activity Barriers and Facilitators Scale; Validity, Reliability, and Cultural Adaptation
Background:The aim of our study is to examine the validity and reliability of the Turkish version of the "Barriers \& Facilitators to Youth Physical Activity Questionnaire" in young individuals after cultural adaptation.
- Conditions
- Youth, Physical Activity, Physical Activity Barriers, Physical Activity Facilitators
- Trial name
- NCT05397561
- Testing
- Turkish Translation of Physical Activity Barriers and Facilitators Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istinye University
Staphylococcus (S.) Aureus Infection
Staphylococcus Aureus Caught in Action at the Site of Infection
This study is to obtain a comprehensive view of S. aureus adaptations in the infected human host and (i) to improve the understanding of the interface between antibiotic therapy, resistance development and virulence factor…
- Trial name
- PROSA (NCT04781569)
- Testing
- data collection, blood draw, nose swabs
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Resistance Training, Muscle Hypertrophy
High- and Low-Load Resistance Training
The goal of this clinical trial is to learn whether low-load resistance training performed to muscle failure can produce similar increases in muscle size and strength as high-load resistance training in healthy untrained young…
- Trial name
- NCT07412600
- Testing
- Low-load resistance training (30% 1RM), High-load resistance training (75% 1RM)
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Athletic Performance, Physical Endurance
Event-Specific Adaptations to CrossFit and Running-Based HIIT in Elite Distance Runners at Moderate Altitude
The goal of this clinical trial is to compare the effects of two high-intensity training programs on physical performance and physiological adaptations in elite male middle- and long-distance runners aged 25 to 35 years who live…
- Conditions
- Athletic Performance, Physical Endurance, Altitude Training Adaptation, Aerobic Capacity
- Trial name
- NCT07675577
- Testing
- Running-Based High-Intensity Interval Training (HIIT), CrossFit-Based High-Intensity Training (CF)
- Where
- Iran
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sistan and Baluchestan
Sedentary Behaviors, Physical Inactivity
Step-Up vs. Running Exercise at Matched Heart Rate Zones in Sedentary Males
This study compares the effects of two aerobic exercise methods - loaded step-up exercise and treadmill running - on cardiovascular fitness, leg strength, heart rate variability, and recovery in sedentary adult males.
- Trial name
- NCT07585617
- Testing
- Loaded Step-Up Exercise, Treadmill Running
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ankara University
Carpal Tunnel Syndrome (CTS), Median Nerve Entrapment
Turkish Adaptation of the CTS-6 Evaluation Tool: A Validation and Reliability Study
The purpose of this study is to develop the Turkish version of the CTS-6 Evaluation Tool and to comprehensively assess its validity and reliability in the Turkish population.
- Conditions
- Carpal Tunnel Syndrome (CTS), Median Nerve Entrapment, Peripheral Nerve Disease, Peripheral Nerve Disorder
- Trial name
- NCT07420049
- Testing
- CTS-6 Evaluation Tool
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Medication Non-adherence
Improving Adherence and Outcomes by Artificial Intelligence-Adapted Text Messages
Uncontrolled hypertension is a major cause of morbidity and mortality and many patients fail to take their antihypertensive medication as prescribed.
- Trial name
- AIM@BP (NCT02454660)
- Testing
- SMS (Text messages)
- Where
- 2 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Major Depressive Disorder 1
Cultural Adaptation of EMDR for Major Depressive Disorder and Compaire Its Online and Face-to-Face Testing
The present study aims to develop a culturally and methodologically adapted EMDR therapy protocol, determine its treatment fidelity, and then clinically test its efficacy in the treatment of Major Depressive Disorder in Pakistan…
- Trial name
- EMDR (NCT06439043)
- Testing
- EMDR Psychotherapy, Online EMDR Psychotherapy
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Khushal Khan Khattak Univeristy, Karak, Pakistan
Heat Intolerance, Heat Stress
Acquiring and Targeting Heat Exposures Necessary for Action
The purpose of this research study is to better understand ways that women and men differ physiologically, cognitively, physically, and cellularly to better prescribe helpful interventions that will prevent injury and risk of…
- Conditions
- Heat Intolerance, Heat Stress, Fatigue; Heat
- Trial name
- ATHENA (NCT05678738)
- Testing
- Antioxidant Berry Supplementation, Acute and Chronic Exercise-Heat Stress
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Follicular Non-Hodgkin's Lymphoma
Study to Evaluate the Efficacy of Response-adapted Strategy in Follicular Lymphoma
Recently, the availability of R has substantially changed therapeutic approach to FL patients, since its combination with chemotherapy has improved response rates, progression free survival (PFS) and overall survival (OS).
- Trial name
- NCT02063685
- Testing
- R-CHOP or R-bendamustine, Observation, Maintenance weekly x4
- Where
- 48 sites in Italy
- Volunteers
- 807 people, healthy volunteers welcome
- Sponsor
- Fondazione Italiana Linfomi - ETS
Trauma, Posttraumatic Stress Disorder
Increasing Treatment Access in Trauma Exposed Children: Developing an Adapted Step One Intervention (Pilot)
One of the most common and widely disseminated trauma treatments is Trauma Focused Cognitive Behavioral Therapy (TF-CBT). TF-CBT is a therapist-led, structured and sequential intervention, with treatment organized around…
- Trial name
- NCT07396935
- Testing
- Personalized Stepped Care Cognitive Behavioral Therapy for Children after Trauma (pSC-CBT-CT)
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.