Clinical trials: Abortion, Induced
Abortion Induced Complicated, Abortion
Second Trimester Abortion With Letrozole and Misoprostol Compared to Misoprostol Alone
Termination of Second trimester Abortion with Letrozole and Misoprostol Compared to Misoprostol Alone
- Trial name
- NCT07767435
- Testing
- · Misoprostol + letrozole, misoprostol alone
- Volunteers
- 80 people
- Sponsor
- Sohag University
Perinatal Death, Hypertension, Pregnancy-Induced
Pregnancy in the Context of Urbanicity and Climate Change. The Overall Aim of the Project is to Co-create, Implement, and Test New Clinical Guidelines in Order to Improve the Quality of Care in Antenatal Clinics in the Context of Urbanisation and Climate Change in Dar es Salaam, Tanzania.
Tanzania's population is growing quickly, and Dar es Salaam is one of the fastest-growing cities in the world. At the same time, the city is increasingly affected by very hot weather, flooding, and air pollution.
- Conditions
- Perinatal Death, Hypertension, Pregnancy-Induced, Abortion, Spontaneous, Stillbirth
- Trial name
- NCT07751432
- Testing
- CC-ANC intervention group.
- Where
- Tanzania
- Volunteers
- 1,060 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Abortion, Induced
To Study the Safety and Efficacy of A Novel Intrauterine Estrogen-Releasing System in Induced Abortion
The purpose of this clinical trial is to evaluate the safety and efficacy of the estradiol-loaded silicone rubber intrauterine stent system for promoting endometrial repair after artificial abortion.
- Trial name
- NCT07381569
- Testing
- Estradiol-Loaded Silicone Rubber Intrauterine Stent System, No-Drug-Loaded Silicone Rubber Intrauterine Stent System
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking Union Medical College Hospital
Induced Abortion
To Study the Safety and Efficacy of Disposable Cyclone Ring in Artificial Abortion
The purpose of this study is to compare the two surgical methods of surgical rotation abortion and surgical negative pressure uterine aspiration with the termination of pregnancy.
- Trial name
- NCT06894732
- Testing
- Rotary induced abortion
- Where
- China
- Volunteers
- 332 people
- Sponsor
- Peking Union Medical College Hospital
Induced Abortion, Instrumental Induced Abortion Between 14 and 16 Weeks of Amenorrhea
Retrospective Study of Surgical Induced Abortions Between 14 and 16 Weeks of Amenorrhea At Croix Rousse University Hospital in Lyon
In France, induced abortions can be carried out by two different methods: the medicinal one, which involves taking medications to expel the pregnancy (MIFEPRISTONE and then MISOPROSTOL), and the instrumental one, which involves…
- Trial name
- TARDIVG (NCT06871618)
- Testing
- Retrospective
- Where
- France
- Volunteers
- 700 people
- Sponsor
- Hospices Civils de Lyon
Legally Induced Abortion Without Mention of Complication
Pre-Operative Effects of Mifepristone on Dilation and Evacuation Services
This research study investigates the use of a drug, mifepristone, given before second trimester abortion. Mifepristone is a medication that is approved for medical abortion during the first trimester.
- Trial name
- POEM (NCT01862991)
- Testing
- Hygroscopic cervical dilators, Misoprostol, Intra-amniotic digoxin
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Stanford University
Abortion, Induced
Value of Mifepristone in Cervical Preparation Prior to Dilation and Evacuation 19-24 Weeks
A common practice for preparation for surgical abortion after 19 weeks gestation is the placement of multiple sets of osmostic dilators 1-2 days prior to the procedure.
- Trial name
- NCT01615731
- Testing
- Mifepristone, Hygroscopic cervical dilators, Misoprostol
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
Abortion, Induced
Mifepristone Versus Laminaria for Cervical Ripening in Midtrimester Induction
Data from other countries have suggested that oral mifepristone used as a cervical ripening agent may decrease induction to delivery time in midtrimester inductions.
- Trial name
- NCT00383032
- Testing
- mifepristone
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Abortion, Induced, Labor Stage, Third/Drug Effects
Oxytocin Infusion vs. Spontaneous Follow-up for Third-stage of Labor After Second-trimester Abortion
This study compares oxytocin infusion to spontaneous follow-up for third-stage of labor at induced mid-trimester abortions. Patients will be randomized to oxytocin infusion or observation with no pharmacologic intervention.
- Conditions
- Abortion, Induced, Labor Stage, Third/Drug Effects, Pregnancy Trimester, Second, Oxytocin/Administration & Dosage
- Trial name
- NCT02485444
- Testing
- Oxytocin
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Ataturk University
Induced Abortion, Medical Abortion
Assessment of Pain During an Abortion With Knowledge of the Predictive Factors of Pain.
Two studies carried out in 2011 at the Center for Contraception and Voluntary Interruption of Pregnancy (CIVG) at the Louis-Mourier Hospital, evaluated the pain of patients undergoing an abortion, and looked for predictors of the…
- Conditions
- Induced Abortion, Medical Abortion, Surgical Abortion, Pain
- Trial name
- NCT05532085
- Testing
- Evaluation of pain during voluntary termination of pregnancy with medication following consideration of predictive factors of pain without an established analgesic protocol, Evaluation of pain during a voluntary medical termination of pregnancy following consideration of predictive factors of pain with an established analgesic protocol, Assessment of pain during voluntary termination of pregnancy by aspiration under local anesthesia following consideration of predictive factors of pain without an established analgesic protocol
- Where
- France
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- Olivier CHASSANY
Pregnancy Complications
Measuring sVAP-1 as a Predictor of Pregnancy Problems
Pre-eclampsia is a common pregnancy disorder defined as high blood pressure and protein in the urine after 20 weeks of pregnancy.
- Trial name
- NCT04891315
- Testing
- Blood test for soluble VAP-1 (sVAP-1).
- Where
- United Kingdom
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Pregnancy Complications, Legally Induced Abortion Without Mention of Complication
Medical Abortion up to 10 Weeks Gestation at Home
Medical abortion performed in the womens home has shown to be safe and acceptable up to 9 weeks of gestation. Our project is aiming to confirm our hypothesis that it is equally effective, safe and acceptable when the gestation is…
- Trial name
- NCT02191774
- Testing
- Medical abortion at home
- Where
- Sweden
- Volunteers
- 273 people
- Sponsor
- Karolinska Institutet
Abortion Induced Complicated
Management of RPOC After Induced Abortion
Randomized trial comparing expectant management and medical management in women diagnosed with retained products of conception after first trimester induced abortion
- Trial name
- RPOC (NCT04685694)
- Testing
- Misoprostol
- Where
- Israel
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Induced Abortion
Same-Day Mifepristone-Misoprostol Compared to Misoprostol Only for Surgical Abortion Cervical Preparation
A randomized double---blinded comparison of same---day mifepristone and misoprostol with misoprostol only for cervical preparation in second---trimester surgical abortion in 100 women at 14 0/7---19 6/7 weeks gestation.
- Trial name
- MMSAP (NCT02412618)
- Testing
- Mifepristone, Misoprostol
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Induced Abortion, Second Trimester Abortion
Midlevel Versus Physician-provided Medical Abortion in the Second Trimester
The purpose of the study is to determine the safety and effectiveness of second trimester medical abortion when provided by nurse midwives compared with physicians.
- Conditions
- Induced Abortion, Second Trimester Abortion, Medical Abortion, Health Personnel
- Trial name
- NCT04181541
- Testing
- Provider type: Physicians, Provider type: Midlevel Providers
- Where
- Ethiopia
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Ipas
Induced Abortion, First Trimester Abortion
Study of Clinic-based Versus Self-use of Medical Abortion Pills
The goal of the study is to determine whether important clinical outcomes differ among women who access a combined medical abortion regimen from a pharmacy when compared with those who access it from a facility.
- Conditions
- Induced Abortion, First Trimester Abortion, Misoprostol, Mifepristone
- Trial name
- MOC (NCT03727308)
- Testing
- Medical abortion pills sourced from pharmacies, Medical abortion pills sourced from health clinics
- Where
- 2 sites in Cambodia, Ghana
- Volunteers
- 4,196 people, healthy volunteers welcome
- Sponsor
- Ipas
Abortion, Induced
Misoprostol Dose and Timing Before Surgical Abortion at 13 to 16 Weeks' Gestation: a Randomized Trial
This study is a blinded randomized trial to compare two different doses and intervals of buccal misoprostol for cervical preparation before surgical abortion at 13 to 16 weeks' gestation: 400 mcg administered 3 hours before D\&E…
- Trial name
- NCT02279914
- Testing
- Misoprostol 400 mcg 3 hours prior to procedure, Misoprostol 600 mcg 90 minutes prior to procedure
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood of Greater New York
Induced Abortion and Complications of Termination of Pregnancy
Embryoscopic Evacuation for Induced Abortion
The investigators intend to assess if hysteroscopic evacuation of gestational tissue, is possible as a tool for early induced abortion with a hysteroscopic morcellator rather than with a traditional dilation and curettage…
- Trial name
- NCT04668547
- Testing
- Hysteroscopic Embryolysis
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Oshri Barell
Abortion, Induced, Abortion, Incomplete
Developing and Testing Interventions to Address Conscientious Objection to Abortion Care in Mexico and South Africa
The primary purpose of this research is to develop strategies and interventions to mitigate the impact of conscientious objection on women's access to safe abortion care in Mexico and South Africa using a user-centered design…
- Trial name
- NCT04290832
- Testing
- CO Intervention
- Where
- 2 sites in Mexico, South Africa
- Volunteers
- 317 people, healthy volunteers welcome
- Sponsor
- Ipas
Abortion, Induced, Cervical Preparation
Gabapentin for Pain Control After Osmotic Dilator Insertion and Prior to D&E Procedure: a Randomized Controlled Trial
Women having abortion procedures between 15 weeks 0 days and 23 weeks 6 days gestational age on the day of their procedure commonly have dilators placed in their cervix overnight before the abortion procedure.
- Conditions
- Abortion, Induced, Cervical Preparation, Pain
- Trial name
- GABA (NCT03080493)
- Testing
- Gabapentin 600mg, acetaminophen/codeine and ibuprofen
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- University of California, Davis