Clinical trials: Abdominal Aortic Surgery
Toraco Abdominal Aneurysm
Clinical Study on the Prevention of Surgical Wound Complications for Aneurysmal Thoracic-abdominal Aortic Pathology Using the "PREVENA" System
The patients will be randomized into two groups of 100 subjects each one. One arm will be randomized to treatment with a negative topical pressure system (Sistema Prevena ™); while the other arm ("control group") will be…
- Trial name
- TVAC (NCT03512470)
- Testing
- Sistema Prevena ™(TVAC), Standard medication
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS San Raffaele
Myocardial Injury After Non-cardiac Surgery
Preoperative BNP and MINS in AAA Open Repair
The aim of this study was to investigate whether preoperative B-type natriuretic peptides serves as an independent predictor of myocardial injury after non-cardiac surgery (MINS) in abdominal aortic aneurysm open repair.
- Trial name
- NCT06088641
- Testing
- preoperative BNP value
- Where
- South Korea
- Volunteers
- 198 people
- Sponsor
- Gangnam Severance Hospital
Abdominal Aortic Aneurism, Surgery
Study of the Glycocalyx in Abdominal Aortic Aneurysm
The investigators want to measure the degradation of the endothelial glycocalyx before and after clamping the aorta, in patients operated for a abdominal aortic aneurism.
- Conditions
- Abdominal Aortic Aneurism, Surgery, Ischemic Reperfusion Injury
- Trial name
- Endo_eAAA (NCT01834092)
- Testing
- Plasma
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Thoracic Aortic Aneurysm, Respiratory Insufficiency
Immunonutrition and Thoracoabdominal Aorta Aneurysm Repair
The purpose of this study is to determine whether immunonutrition and pre operative nutrition can reduce lenght of respirator support, lenght of stay in the ICU and incidence of post operative infections
- Trial name
- NCT00339053
- Testing
- Immunonutrition ( Impact)
- Where
- Netherlands
- Volunteers
- 142 people
- Sponsor
- St. Antonius Hospital
Abdominal Aortic Aneurism, Abdominal Aortic Rupture
Haemostasis Management of Abdominal Aortic Procedures
Comparative study on efficacy of haemostatic therapy guided either by standard laboratory coagulation parameters or point-of-care testing in patients undergoing vascular surgical procedures.
- Conditions
- Abdominal Aortic Aneurism, Abdominal Aortic Rupture, Perioperative/Postoperative Complications, Surgical Blood Loss
- Trial name
- NCT03426839
- Testing
- Coagulation tests
- Volunteers
- 40 people
- Sponsor
- University of Pecs
Abdominal Aortic Surgery
The Effect of Intraperitoneal Injection of Magnesium Sulphate Versus Dexmedetomidine as an Adjuvant to Bupivacaine on Postoperative Analgesia in Patients Undergoing Abdominal Aortic Surgery
optimal management of postoperative pain is essentiel for better outcome in abdominal aortic surgery.the study aim to compare between analgesic effect of magnesium sulphate versus dexmedetomidine as an adjuvant to bupivacaine…
- Trial name
- NCT05577260
- Testing
- magnesuim sulphate, Dexmedetomidine, isobaric bupivacaine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Abdominal Aortic Aneurysm
Structured Exercise Programme and Abdominal Aortic Aneurysm Surgery
There is a relationship between aerobic fitness and survival both with and without surgery. Some patients can improve their aerobic fitness with a structured exercise programme but currently it is not know how much this could…
- Trial name
- NCT03985202
- Testing
- Structured exercise programme
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Torbay and South Devon NHS Foundation Trust
Infrarenal Abdominal Aortic Aneurysm
Arterial Stiffness, Blood Pressure and Cardiac Output Study
Comparison of non-invasively obtained central blood pressure using SphygmoCor and invasively recorded central blood pressure in patients with an AAA that will be treated with EVAR.
- Trial name
- ABC (NCT03469388)
- Testing
- Pulse wave analyses; central blood presaure parameters
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Rijnstate Hospital
Thoracic Aneurysm
Effectiveness of Acetazolamide in Reducing Paralysis of the Leg in Patients Undergoing Aortic Aneurysm Surgery Surgery
The aorta is a large vessel that carries blood away from the heart. Sometimes it becomes dilated (swells) and this is known as 'aneurysm'. It may cause either dissection (splitting of the wall) or rupture (bursting).
- Trial name
- AZATAAR (NCT01889498)
- Testing
- Acetazolamide
- Where
- 2 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Abdominal Aortic Aneurysm
Prognostic Impact of NLR, PLR, and MPV in Patients Undergoing AAA Open Repair
Abdominal aortic aneurysm (AAA) is a multifactorial degenerative disorder, which if untreated might lead to catastrophic complications.
- Trial name
- NCT05031195
- Testing
- 1st tertile, 2nd tertile, 3rd tertile
- Where
- South Korea
- Volunteers
- 334 people
- Sponsor
- Gangnam Severance Hospital
Aortic Aneurysm, Abdominal
Clinical Outcomes of Patients Treated With Open Surgical Repair for Complex Aortic Aneurysms
This is a prospective, non-randomized, single center, data collection study of patients treated with open surgical repair (OR) for complex aortic aneurysms (CAAs).
- Trial name
- NCT03446287
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Mayo Clinic
Hemodynamic Instability
Hemodynamic Monitoring During Abdominal Aortic Surgery
This trial investigates the ability of our istitutional algorithm in maintaining a safe hemodynamics during abdominal aorta open surgery, in terms of limitation of intraoperative hypotension incidence
- Trial name
- HEMAS (NCT05478564)
- Testing
- Intraoperative fluids and vasoactive drugs management protocol
- Where
- Italy
- Volunteers
- 63 people
- Sponsor
- Humanitas Clinical and Research Center
Abdominal Aortic Aneurysm
Evaluation of the Impact of Prehabilitation on Recovery Following Open Surgery for Abdominal Aortic Aneurysm
This is a pilot, prospective, randomized control trial that aim to provide a first estimation of the 3-month post-operative variation in the functional recovery of patients who benefited from an outpatient pre-habilitation…
- Trial name
- EPOP-AORTA (NCT05375292)
- Testing
- PREHABILITATION
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Toulouse
Aortic Aneurysm, Abdominal, Aortic Diseases
Haemodynamic Response to Aortic Surgery
Open elective abdominal aortic surgery is a high risk procedure involving clamping of the aorta. Indications include abdominal aortic aneurysm (AAA) or aortic occlusive disease (AOD) causing lower limb ischaemia.
- Conditions
- Aortic Aneurysm, Abdominal, Aortic Diseases, Acute Kidney Injury
- Trial name
- NCT01704391
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- Sygehus Lillebaelt
Aortic Aneurysm
Melatonin and Cardiac Outcome After Major Surgery
The purpose of this study is to assess whether treatment with melatonin can reduce cell damage and inflammatory stress response and thereby occurrence of myocardial injury after abdominal aortic surgery.
- Trial name
- NCT00315926
- Testing
- Melatonin
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Delirium, AAA
Abdominal Aortic Aneurysm Patients Remain at Risk for Delirium on the Surgical Ward After Intensive Care Unit Dismissal
The incidence of delirium following open abdominal aortic aneurysm (AAA) surgery is significant, with incidence rates ranging from 12 to 33%.
- Conditions
- Delirium, AAA, Intensive Care Unit Delirium, Surgery--Complications
- Trial name
- NCT04080557
- Testing
- Surgery
- Where
- Netherlands
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Amphia Hospital
Aortic Aneurysm, Abdominal
TAP-Block in Abdominal Aortic Surgery
The primary outcome of this study was the evaluation of the efficacy of TAP block on pain intensity following open abdominal aortic surgery.
- Trial name
- TAP-CACAO (NCT03657979)
- Testing
- Ropivacaine
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Aneurysm Aortic, Vascular Diseases
F-BEVAR vs Open Surgery for Complex Abdominal Aortic Aneurysm
The aim of the present study was to investigate outcomes of a propensity matched series of patients treated with F-BEVAR and open surgery repair for complex abdominal aortic aneurysm in two aortic high-volume centres.
- Trial name
- NCT05247944
- Testing
- Fenestrated and branched endovascular aortic repair (F-BEVAR), Open repair
- Volunteers
- 278 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
General Anesthesia, Vascular Surgery
BNP and Vascular Surgery
Background and rationale of the study: Patients undergoing non-cardiac major surgery show a perioperative cardiac risk and postoperative complications, that can be stratified based on parameters linked to patient's conditions and…
- Conditions
- General Anesthesia, Vascular Surgery, Abdominal Aortic Aneurysm, Natriuretic Peptide, Brain
- Trial name
- BNPinVasc (NCT03926104)
- Where
- Italy
- Volunteers
- 165 people
- Sponsor
- University of Parma
Aortic Aneurysm
Preventing Myocardial Ischemia by Preconditioning in Elective Operation for Abdominal Aortic Aneurysm
Primary To investigate whether peripheral predonditioning induced by brief, intermittent constriction of blood supply to an arm can reduce the incidence of perioperative myocardial ischemia in patients operated electively for…
- Trial name
- NCT01523262
- Testing
- preconditioning
- Where
- 2 sites in Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital