Clinical trials: ART
Infertility, in Vitro Fertilization (IVF)
Use of Artificial Intelligence for Clinical Assessment of Assisted Reproductive Techniques and IVF Outcomes
The use of machine learning techniques using an artificial intelligence tool is proposed to analyze clinical data to predict best possible IVF/ART outcomes.
- Conditions
- Infertility, in Vitro Fertilization (IVF), ART
- Trial name
- AI in ART (NCT04255615)
- Testing
- AI to analyze 3 D ultrasound
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
HIV
Metabolomics Fingerprinting and Metabolic Dynamics After HIV Infection
The purpose of this plot study is to find out the relationship between metabolic changes and anti-retroviral therapy (ART), life style and clinical conditions of HIV-infected patients using nuclear magnetic resonance (NMR) based…
- Trial name
- NCT01828268
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sichuan Academy of Medical Sciences
Aging
Evaluation of the Efficacy and Safety of an Injectable Hyaluronic Acid-based Filler, Art Filler® Volume: Comparative Single-blind Study of the Non-inferiority Versus Juvéderm® Voluma on the Midface, Temple and Jaw-line and Non-comparative Study on the Chin. (AF3)
The function of injectable fillers for the treatment of dermal contour deformities is to smooth dermal depressions formed by the loss of volume.
- Trial name
- AF3 (NCT04645576)
- Testing
- Face correction with injectable fillers
- Where
- France
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Laboratoires FILLMED
Infertility
Environment and Reproductive Health; Human Exposure to Bisphenol A, Phthalates and Fertility and Pregnancy Outcomes
The purpose of the study is to investigate the relationship between environmental agents and reproductive health. Environmental agents of interest include exposure to chemicals such as polychlorinated biphenyls (PCBs), flame…
- Trial name
- EARTH (NCT00011713)
- Testing
- Completion questionnaires/providing biological samples
- Where
- United States
- Volunteers
- 1,474 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Malaria
Study of Pharmacokinetics and Pharmacodynamics of Artesunate in Pregnant Women in the Democratic Republic of Congo
The objective of this study is to assess the pharmacokinetics (PK) and pharmacodynamics (PD) of a standard dose of orally administered artesunate, in order to determine if the current adult dose (200 mg) is appropriate in…
- Trial name
- NCT00538382
- Testing
- Artesunate
- Where
- Democratic Republic of the Congo
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Pregnancy, Live Birth
Folic Acid and Zinc Supplementation Trial (FAZST)
The overarching goal of this trial is to determine if an intervention comprising folic acid and zinc dietary supplementation improves semen quality and indirectly fertility outcomes (i.e., live birth rate) among couples trying to…
- Conditions
- Pregnancy, Live Birth, Spontaneous Abortion
- Trial name
- FAZST (NCT01857310)
- Testing
- 5 mg folic acid and 30 mg elemental zinc
- Where
- 4 sites in United States
- Volunteers
- 2,370 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Tuberculosis, HIV/AIDS
TB Reduction Through ART and TB Screening Project
Tuberculosis (TB) has overtaken HIV as the leading infectious cause of death worldwide and requires a major policy shift for it to be controlled in line with the WHO Stop-TB goal to "end TB".
- Trial name
- TREATS (NCT03739736)
- Testing
- Combination of TB/HIV prevention activities (arm A), Combination of TB/HIV prevention activities (arm B), Standard of care (arm C)
- Where
- 2 sites in South Africa, Zambia
- Volunteers
- 4,200 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Dental Caries
Occlusal-proximal ART Restorations in Primary Molars Using 2 Different Kinds of GIC
The aim of this research is to investigate the survival rate and cost effectiveness of two brands of GIC as occlusal-proximal ART restorations. Also the survival rate of the tooth will be investigated.
- Trial name
- NCT02267720
- Testing
- Occlusal-proximal ART restorations - Ketac Molar, Occlusal-proximal ART restorations - Vitro Molar
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Alzheimer's Disease (Incl Subtypes), Depressive Symptoms
Beyond Listening: A Music-based Intervention
Study will be conducted to determine if caregivers who use music at home will feel less burden and whether the person they are caring for will demonstrate decreased symptoms of dementia.
- Trial name
- NCT04840173
- Testing
- Music
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- MJHS Institute for Innovation in Palliative Care
Retention
A Clinical Trial to Assess the Retention and Caries Preventive Effects of Moisture Tolerant Resin Sealant and ART Sealants
It is a clinical trial which employs a split mouth design to assess the retention of a moisture tolerant resin based sealant and the ART(Atraumatic restorative treatment) sealants on a representative sample of 7- 12 year old…
- Trial name
- NCT02716558
- Testing
- ART Sealant Application, Resin sealant application
- Where
- India
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Dr. Praveen B.H
Ovarian Hyperstimulation
Progesterone Diurnal Rhythm During Ovarian Stimulation for IVF
To evaluate the influence of circadian rhythm on progesterone levels during follicular phase of natural cycle and during follicular phase of controlled ovarian stimulation during IVF.
- Trial name
- NCT02975713
- Where
- United Arab Emirates
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
HIV Infections, Gonorrhea
Cellulose Sulfate (CS) Gel and HIV in Nigeria
This is a Phase 3, multi-center, randomized, placebo-controlled trial to determine the effectiveness and safety of the 6% cellulose sulfate (CS) vaginal gel for the prevention of HIV infection.
- Conditions
- HIV Infections, Gonorrhea, Chlamydia Infections
- Trial name
- NCT00120770
- Testing
- Cellulose Sulfate Vaginal Gel (Microbicide)
- Where
- 2 sites in Nigeria
- Volunteers
- 2,160 people, healthy volunteers welcome
- Sponsor
- FHI 360
Cognitive Impairment
Geriatric Inclusive Art: Effects of Painting Sessions on Older In-patients With Cognitive Decline
Geriatric Inclusive Art (GIA) painting activity is a new form of art therapy, which has been adapted for older adults hospitalized in medical wards.
- Trial name
- GIA (NCT03624387)
- Testing
- Painting Sessions
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Jewish General Hospital
HIV Infections, AIDS
Pilot Project of Virologic and Immunologic Correlates of GALT Immune Reconstitution Following Raltegravir Therapy
This research is being done to study how the immune system in the small intestine improves after taking antiretroviral (anti-HIV) medications.
- Trial name
- NCT00661960
- Testing
- raltegravir, efavirenz
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
HIV/AIDS
Behavioural Text Messages to Improve Retention in Care in South Africa
The proportion of South Africans aware of their HIV status and on treatment remains lower than optimal. The goal of this study is to rapidly determine whether text messages framed according to behavioural economics principles…
- Trial name
- NCT05010291
- Testing
- Standard of Care (SOC) text message reminder to attend clinic appointment, Loss aversion framed text message reminder to attend clinic appointment, Social norms framed text message reminder to attend clinic appointment
- Where
- South Africa
- Volunteers
- 1,541 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
HIV/AIDS
The Incidence and Severity of Drug Interactions Before and After Switching Antiretroviral Therapy to Bictegravir/Emtricitabine/Tenofovir Alafenamide in Treatment Experienced Patients
This study will assess changes in the incidence and severity of drug interactions before and after switching antiretroviral therapy to bictegravir/emtricitabine/tenofovir alafenamide-based regimens in treatment experienced…
- Trial name
- NCT03789968
- Testing
- bictegravir/emtricitabine/tenofovir alafenamide
- Where
- United States
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Healthy
Time of Treatment in HALL Technique Vs ART
The goal of this clinical trial is to assess the time of treatment of Hall Technique versus Atraumatic Restorative Technique in the management of carious primary molars.
- Trial name
- NCT06594770
- Testing
- Atraumatic Restorative Treatment, Hall technique
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Adherence to Medication Regime
Early Antiretroviral Therapy and Pre-exposure Prophylaxis for HIV Prevention Among Female Sex Workers in Cotonou, Benin
In the last few years, early treatment of HIV-infected individuals, or "treatment as prevention (TasP), and pre-exposure prophylaxis with antiretroviral drugs among HIV-negative people at very high-risk of acquiring the infection…
- Trial name
- TasP/PrEP (NCT02237027)
- Testing
- TasP using ART regimen as per Benin guidelines, PrEP using Truvada
- Where
- Benin
- Volunteers
- 361 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
HIV/AIDS
Outcomes of Differentiated Models of Antiretroviral Treatment (ART) Provision
The aim of this study is to evalulate the effectiveness and cost-effectiveness of three models of ART provision for stable ART patients.
- Trial name
- [MMD] (NCT03438370)
- Testing
- Three monthly ART supply at CAGs, Six monthly ART supply at outreaches
- Where
- Lesotho
- Volunteers
- 5,760 people, healthy volunteers welcome
- Sponsor
- Equip, Lesotho
Arthroscopic Surgical Procedures
Effects of VR and White Noise During Arthroscopy (VR/WN_ ART)
Background: Today, arthroscopy is widely used in the diagnosis and of treatment intra-articular diseases. Arthroscopy is considered a procedure that disturbs the patient's comfort because it is a very invasive and painful…
- Trial name
- (VR/WN_ ART) (NCT05992714)
- Testing
- Virtual Reality Glasses group, white noise group
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Seher Tanrıverdi