Clinical trials: A Randomized Controlled Trial
Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc)
Pragmatic RCT of AI-Assisted Reading for Malignant Hepatic Lesions on CE-CT
The purpose of this multicenter pragmatic randomized controlled trial is to determine whether AI-assisted interpretation of multiphasic liver contrast-enhanced computed tomography (CE-CT) is non-inferior to standard radiology…
- Conditions
- Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc), Hepatic Metastasis, Hepatic Hemangioma
- Trial name
- NCT07768085
- Testing
- AI-assisted abdominal CE-CT reporting, Standard abdominal CE-CT reporting without AI assistance
- Where
- China
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Gingival Recession
Treatment of Gingival Recession Defects Using Platelet-Rich Fibrin With an Allogenic Dermal Matrix
The study aims to test the non-inferiority of an Allogenic Dermal Matrix with Platelet-Rich Fibrin for treatment of gingival recessions in comparison to the Connective Tissue Graft.
- Trial name
- NCT05819515
- Testing
- Tunneled coronally advanced flap
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Exercise Overtraining
Hydrogen-Infused Water for Endurance Performance, Body Hydration Biomarkers, and Health-Related Quality of Life
The study investigates the impact of 4-week hydrogen-infused water consumption on various health and performance outcomes. Conducted with healthy young adults, the trial assesses endurance performance, hydration biomarkers, and…
- Trial name
- HYDRO2EAU (NCT06788015)
- Testing
- Hydrogen-infused water
- Where
- Serbia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Malnutrition, Child
Effectiveness of a Positive Deviance Program in Reducing Childhood Undernutrition
Globally, childhood malnutrition remains a public health concern. Malnutrition can be diverse from undernutrition to overnutrition.
- Trial name
- NCT04688515
- Testing
- Nutrition program developed using positive deviance approach
- Where
- Malaysia
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Sedentary Healthy Young Individuals
The Effect of Square Stepping Exercises Training on Lower Extremity
Physical activity plays an indispensable role to lead a healthy life. Square-stepping exercises (SSE) are aerobic exercises.Our study was designed to investigate the effects of square-stepping exercise training on lower-extremity…
- Trial name
- NCT04910035
- Testing
- Exercises Training
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Blood Pressure, Physical Inactivity
The Effectiveness of an Exergame-based Intervention
This randomized control trial aims to compare the effects of a regular exergame-based intervention and a regular moderate-intensity endurance exercise in healthy individuals.
- Trial name
- NCT05712317
- Testing
- Exergame Intervention, Moderate-intensity endurance exercise
- Where
- Switzerland
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Bern
Gingivitis; Chronic
Zinc Stents for the Treatment of Gingivitis
Background This study investigates the effects of zinc-containing stents on gingival inflammation, bleeding, and plaque regrowth in gingivitis patients.
- Trial name
- NCT06888440
- Testing
- scaling and zinc stents
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Opioid Misuse
A Digital Intervention to Prevent the Initiation of Opioid Misuse in Adolescents in School-based Health Centers
The primary hypothesis of this study is that at 3 months, there will be a higher proportion of intervention participants vs. control participants who report greater risk of harm from misuse of prescription opioids AND heroin.
- Trial name
- NCT04941950
- Testing
- PlaySmart, Video Game Control
- Where
- 15 sites in United States
- Volunteers
- 533 people, healthy volunteers welcome
- Sponsor
- Tyra Boomer
Postpartum Complication, Posttraumatic Stress Symptoms
Labor Education to Reduce Postpartum Traumatic Stress
The goal of this randomized controlled trial is determine if education on common events in labor in nulliparous women can reduce the postpartum traumatic symptoms.
- Trial name
- LEPT (NCT06992791)
- Testing
- Prenatal Education on Childbirth
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Trait Schizotypy
Emotion Regulation in Trait Schizotypy
Our aim is to compare state anger and state emotion regulation strategies in healthy individuals with high trait schizotypy and to look at differences of induced anger, negative emotions, decrease of positive emotions and…
- Trial name
- NCT03694574
- Testing
- instruction to suppress, instruction to reappraise, control
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Danube University Krems
Mental Health, Well-being
The Effectiveness of a Positive Psychology App in the General Population
The corona crisis has a negative impact on the mental wellbeing of the Dutch population. Positive psychology exercises (PPOs) can potentially improve mental well-being and reduce mild and moderate psychological complaints.
- Conditions
- Mental Health, Well-being, Depression, Anxiety
- Trial name
- NCT05292560
- Testing
- Training in positivity
- Where
- Netherlands
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Twente
Amino Acids, Milk
Determination of the Postprandial Amino Acid Uptake Kinetics of Yoghurt Vs Milk.
Subjects will visit the study site twice in a fasting state. Subjects asked to consume one of the two study products in a random order. Subjects will consume one serving of the study product (T = 0 minutes).
- Conditions
- Amino Acids, Milk, Yoghurt
- Trial name
- NCT06628024
- Testing
- Milk, Yoghurt
- Where
- Netherlands
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Quality of Life, Cancer of Endometrium
FitEx for Endometrial Cancer Survivors
The purpose of this study is to determine whether a physical activity tracking program called FitEx would be useful to endometrial cancer survivors.
- Conditions
- Quality of Life, Cancer of Endometrium, Behavior, Health, Self Efficacy
- Trial name
- NCT05233059
- Testing
- FitEx, Weekly Yoga Sessions, Weekly Movement Sessions
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Interdisciplinary Communication
A Comparison Between Physical and Virtual Simulation: A Randomized Controlled Trial
Nurse-physician communication skills can be improve through inter-professional team training. Simulation is often used to conduct these training.
- Trial name
- NCT04330924
- Testing
- Create Real-life Experience And Teamwork In Virtual Environment (CREATIVE)
- Where
- Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Healthy
Effect of 12-week Probiotic Consumption Immobilized on Oat Flakes on Blood and Urine Biomarkers and Human Microbiome
The purpose of this clinical trial was to evaluate the effects Lactococcus cremoris spp. im-mobilized on oat flakes on human microbiome and blood and urine biomarkers of associated with human health.
- Trial name
- FOODBIOMES CT2 (NCT06293859)
- Testing
- Probiotic oat flakes, Conventional oat flakes
- Where
- Greece
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of the Aegean
Calcinosis Cutis
Efficacy of Intralesional Sodium Thiosulfate Versus Intralesional Saline for Dystrophic and Idiopathic Calcinosis Cutis
The purpose of our research is to compare the effectiveness of 125mg/50ml sodium thiosulfate (STS) solution to normal saline (0.9% sodium chloride) when injected intralesionally for the treatment of calcinosis cutis.
- Trial name
- NCT03639779
- Testing
- Sodium Thiosulfate, Saline Solution
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Postpartum Hemorrhage
Efficacy of Four Different Treatment Regimes on Postpartum Hemorrhage
Postpartum hemorrhage is the most important cause of maternal morbidity and mortality worldwide and accounts for approximately 25% of deaths worldwide.
- Trial name
- NCT05467462
- Testing
- I.V carbetocin administration, I.V Oxytocin administration, I.V carbetocin and tranexamic acid administration
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Menthol Cigarettes, Smoking Behavior
DoubleTake: Effect of Message Exposure Via a Discrete Choice Experiment With Eye-Tracking on Quit Attempts Among Adults Who Smoke Menthol Cigarettes
<p>The goal of this clinical trial is to learn how exposure to anti-smoking social media messages affects quitting-related behaviors.
- Conditions
- Menthol Cigarettes, Smoking Behavior, Cigarette Use
- Trial name
- NCT07782879
- Testing
- Message Exposure via Discrete Choice Experiment
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Second Stage of Labor
Caffeine in the Second Stage of Labor in Low-risk Nulliparous Mothers at Term
Single blind, randomized control trial to determine benefit of caffeine and sodium benzoate on the second stage of labor
- Trial name
- NCT05906303
- Testing
- Caffeine and Sodium Benzoate Injection, Normal Saline
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Reading Hospital and Medical Center
Healthy
Single and Multiple Ascending Dose Study of JW1601 for Healthy Volunteers
This study is conducted to evaluate the safety/tolerability and PK/PD of JW1601 after oral administration in healthy Korean, Caucasian and Japanese adult volunteers
- Trial name
- NCT04018170
- Testing
- Study drug
- Where
- 2 sites in South Korea
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- JW Pharmaceutical
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