Clinical trials: Total Mesorectal Excision
Rectal Cancer
Introduction and Influence of Total Mesorectal Excision (TME) in the Treatment of Rectal Cancer
Total mesorectal excision (TME) is a rather new operation technique in the treatment of rectal cancer. It is known to reduce the rate of local recurrences. However, the influence on long-term survival is unclear.
- Trial name
- NCT00910143
- Testing
- conventional rectal surgery, total mesorectal excision
- Where
- Switzerland
- Volunteers
- 194 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Single-Port Colorectal Surgeries
A Real-World Study to Evaluate the Clinical Performance and Safety of da Vinci SP Surgical System for Single-Port Colorectal Surgeries（SPiM-RWS-CR）
A real-world study to evaluate the clinical performance and safety of da Vinci SP Surgical System ("SP single-port robot" for short) for single-port robot-assisted colorectal surgeries in the real world, providing a real world…
- Trial name
- NCT06141421
- Testing
- procedure
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Ruijin Hospital
Rectal Cancer
ELRR by TEM Versus Laparoscopic TME in iT2N0M0 SMALL LOW RECTAL CANCER
The present prospective randomized study investigated the results of ELRR (ENDOLUMINAL LOCO-REGIONAL RESECTION BY TRANSANAL ENDOSCOPIC MICROSURGERY) versus LTME (LAPAROSCOPIC TOTAL MESORECTAL EXCISION) in the management of 100…
- Trial name
- ELRRvsLTME (NCT01609504)
- Testing
- ELRR BY TEM, LTME
- Volunteers
- 283 people
- Sponsor
- University of Roma La Sapienza
Rectal Cancer
Flexible Colonoscope Assisted Hybrid Transanal Total Mesorectal Resection (taTME)
The investigators propose to use flexible endoscopy combined with transanal total mesorectal resection to further reduce anal injury.
- Trial name
- NCT06380855
- Testing
- Flexible colonoscope assisted hybrid transanal total mesorectal resection
- Where
- China
- Volunteers
- 5 people
- Sponsor
- Sun Yat-sen University
Rectal Cancer
J-pouch Versus Side-to-end Coloanal Anastomosis After Preoperative Radiotherapy and Total Mesorectal Excision for Rectal Cancer
The objective of this study was to compare the functional and surgical results of the J-pouch with those of the side-to-end anastomosis and their impact on quality of life.
- Trial name
- NCT00956241
- Testing
- j-pouch coloanal anastomosis, side-to-end coloanal anastomosis
- Where
- Netherlands
- Volunteers
- 127 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Low Rectal Cancer
Outcomes of TAMIS-Total Mesorectal Excision Versus Transanal Loco-regional Excision for T2 Low Rectal Cancer
Cases with stage T2 N0 low rectal cancer will undergo either Transanal minimally invasive total mesorectal excision or transanal minimally invasive locoregional resection.
- Trial name
- TAMIS (NCT02488577)
- Testing
- Transanal minimally invasive total mesorectal excision, transanal minimally invasive locoregional resection
- Volunteers
- 50 people
- Sponsor
- Osama Mohammad Ali ElDamshety
Adenocarcinoma of the Rectum
Can we Save the Rectum by Watchful Waiting or TransAnal Surgery Following (Chemo)Radiotherapy Versus Total Mesorectal Excision for Early REctal Cancer?
Bowel cancer is the second most common tumour with 41 000 new cases diagnosed annually in the UK, 447 000 across Europe and 1.36 million worldwide; of which one third are located in the rectum.
- Trial name
- STAR-TREC (NCT02945566)
- Testing
- Standard TME surgery, Long course concurrent chemoradiation with capecitabine and radiotherapy, Short course radiotherapy
- Where
- 5 sites in Belgium, Denmark and 3 more
- Volunteers
- 380 people
- Sponsor
- University of Birmingham
Colorectal Neoplasm
A LAparoscopic and TransAnal Total Mesorectal Excision (TME) for Rectal Cancer Trial
All patients planned for an anterior resection due to rectal cancer with a total mesorectal excision are included. This is a feasibility study, thus no randomization will be performed.
- Trial name
- LATA (NCT02324556)
- Where
- 2 sites in Sweden
- Volunteers
- 6 people
- Sponsor
- Sahlgrenska University Hospital
Rectal Cancer
Chinese TaTME Registry Collaborative
Total mesorectal excision (TME) is the gold standard procedure for treating rectal cancer. However, in patients with obesity, prostate hypertrophy, low located tumor or/and pelvic stenosis, the traditional laparoscopic or open…
- Trial name
- NCT03416699
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Beijing Friendship Hospital