Clinical trials: Post-Traumatic Stress Disorder, PTSD
Psychopathic Personality Trait
Can Psychopathy be Prevented? Clinical, Neuroimaging and Genetic Data
The goal of this clinical trial was to learn about the effect of maltreatment on psychological and brain characteristics in a group of children.
- Trial name
- NCT06028620
- Testing
- Trauma Focused-Cognitive Behavior Therapy
- Where
- Mexico
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
Arthrogryposis, Craniofacial Abnormalities
Study of Quality of Life in Freeman-Sheldon Syndrome and Related Conditions
Freeman-Sheldon syndrome (FSS) is a rare human neuromusculoskeletal disorder present before birth, involving primarily limb and craniofacial deformities.
- Conditions
- Arthrogryposis, Craniofacial Abnormalities, Posttraumatic Stress Disorder, Depressive Disorder
- Trial name
- FSS-QLS (NCT01307475)
- Testing
- PTSD Checklist-Specific, Modified Flanagan Quality of Life Scale, Center for Epidemiologic Studies Depression Scale
- Where
- 2 sites in United States, Guatemala
- Volunteers
- 6 people
- Sponsor
- Freeman-Sheldon Research Group, Inc.
Autism Spectrum Disorder, Depression - Major Depressive Disorder
Mental Health, Intellectual and Neurodevelopmental Disorder Detection With Artificial Intelligence Models
This study investigates whether AI-driven analysis of speech can accurately predict clinical diagnoses and assess risk for various mental or behavioral health conditions, including attention-deficit/hyperactivity disorder (ADHD)…
- Conditions
- Autism Spectrum Disorder, Depression - Major Depressive Disorder, Anxiety, Generalized, Bipolar Disorder (BD)
- Trial name
- MINDAIM (NCT06792175)
- Testing
- Solicue Machine Learning Models, Mercuria Machine Learning Models
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Psyrin Inc.
Posttraumatic Stress Disorder
Biomolecular Characteristics of Reminder-Focused Positive-Psychiatry
Objective: Posttraumatic stress disorder (PTSD) is a prevalent neuropsychiatric disorder in children and is associated with increased neurovascular inflammation, suicidality, adulthood mental health disorder, and major adverse…
- Trial name
- RFPP (NCT04529031)
- Testing
- Reminder Focused Positive Psychiatry, attentional control condition (group process)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Los Angeles
Posttraumatic Stress Disorder, Aggressive Behaviour
Reintegrating Children Living at Landfills in Burundi Into Society by Means of a Comprehensive Family Program Addressing Maltreatment and Mental Health Symptoms
Children living at the landfills of Bujumbura are often exposed to maltreatment, including emotional neglect and physical abuse, and traumatic experiences. Furthermore, they grow up in severe poverty.
- Conditions
- Posttraumatic Stress Disorder, Aggressive Behaviour, Parental Maltreatment, Days Spent at the Landfill
- Trial name
- NCT03846154
- Testing
- Comprehensive family intervention including individual sessions of FORNET
- Where
- Burundi
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Sickle Cell Disease, Pain
Effect of EMDR for Reduction of Pain Interference in Children With Sickle Cell Disease
Children with sickle cell disease may experience frequent painful episodes. This, together with the traumatic experiences during a hospitalization, can lead to the development of posttraumatic stress reactions.
- Conditions
- Sickle Cell Disease, Pain, Pain, Chronic Disease
- Trial name
- RELAX (NCT07001631)
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR)
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Post Traumatic Stress Disorder
An Evaluation of the Long-Term Safety and Efficacy of TSND-201 for the Treatment of PTSD
This study is evaluating the long-term safety and efficacy of TSND-201 in adults with PTSD. Participants that have completed a double-blind clinical trial with TNSD-201 for PTSD will be invited to participate in this open-label…
- Trial name
- EMPOWER-EXT (NCT07670702)
- Testing
- TSND-201
- Where
- 17 sites in United States
- Volunteers
- 300 people
- Sponsor
- Transcend Therapeutics
PTSD
Supported Education Pilot
The goal of this project is to gather data necessary for a full scale trial of a supported education service for OIF/OEF veterans with PTSD.
- Trial name
- SEd (NCT01073657)
- Testing
- Supported Education, General Peer Support
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Trauma, Mental Health Disorder
Investigating the Effect of Evidence-based Treatment for Post-traumatic Stress Disorder Among Youth
Trauma-focused cognitive-behavioral therapy (TF-CBT) is an evidence-based practice (EBP) for the treatment of posttraumatic stress disorder (PTSD) and posttraumatic stress symptoms (PTSS) among children and adolescents.
- Conditions
- Trauma, Mental Health Disorder, PTSD, Implementation
- Trial name
- NCT05226481
- Testing
- Trauma-focused cognitive behavioral therapy (TF-CBT)
- Where
- Norway
- Volunteers
- 216 people
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Siblings, Childhood Cancer
SibACCESS: Developing a Telehealth Intervention to Address Unmet Psychosocial Needs of Siblings of Children With Cancer
This study aims to address barriers to psychosocial care for siblings of children with cancer by piloting a group-based telehealth program for adolescent siblings of youth with cancer.
- Conditions
- Siblings, Childhood Cancer, Pediatric Cancer, Posttraumatic Stress Disorder
- Trial name
- R03 CA259898 (NCT04889755)
- Testing
- SibACCESS
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Posttraumatic Stress Disorder
Stepped Care for Young Children After Trauma
The aim of this R34 study is to develop and test the feasibility of a Stepped Care intervention for young children with Posttraumatic Stress Disorder (PTSD).
- Trial name
- NCT01603563
- Testing
- Stepped Care TF-CBT, Standard TF-CBT
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of South Florida
Posttraumatic Stress Disorder, Depression
Controlled Trial of Early Intervention With Children and Adolescents Exposed to Nonrelational Traumatic Events
Background: International studies have shown that a substantial number of children and adolescents are exposed to potentially traumatic events.
- Conditions
- Posttraumatic Stress Disorder, Depression, Anxiety
- Trial name
- NCT02299583
- Testing
- Preventive intervention trauma-informed early intervention
- Where
- Denmark
- Volunteers
- 684 people
- Sponsor
- Carolina Magdalene Maier
Depression and Suicide Ideation, Anxiety
Culturally Adapted Psychological Support for Conflict-Affected Afghans: Study Protocol on Mental Health & Violence
This pilot study examines the feasibility and acceptability of a culturally adapted psychological intervention-Problem Management Plus with Emotional Processing (PM+ EP)-for young Afghans aged 16-30 experiencing high…
- Conditions
- Depression and Suicide Ideation, Anxiety, PTSD
- Trial name
- NCT06980441
- Testing
- Problem Management Plus with Emotional Processing module
- Where
- Afghanistan
- Volunteers
- 60 people
- Sponsor
- Peace of Mind Association (PoMA)
PTSD - Post Traumatic Stress Disorder, PTSD-Related Functional Impairment in Children and Adolescents
Development of the PTSD-iMPACT to Measure PTSD-Related Functional Impairment in Children and Adolescents - A Validation Study in Switzerland and Germany
Population-based and clinical studies indicate that a substantial proportion of children and adolescents are exposed to one or more potentially traumatic events (PTEs) Approximately 16 % of those affected by childhood trauma go…
- Trial name
- PTSD-iMPACT (NCT07368166)
- Where
- 11 sites in Germany, Switzerland
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
PTSD - Post Traumatic Stress Disorder, Substance Use
CBITS-RTM Pilot Study
This pilot study, conducted in partnership with juvenile detention centers, evaluates an adapted CBITS-RTM intervention delivered in a detention school setting.
- Trial name
- NCT07682441
- Testing
- Adapted Cognitive Behavioral Intervention for Trauma in Schools (CBITS) with a Racial Trauma Module (RTM)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of California, San Francisco
CPTSD, Compelx Post-traumatic Stress Disorder
The Effectiveness of Group Guided Written Exposure Therapy for CPTSD Symptoms Among Adolescents
This study aims to examine the effectiveness of group-delivered Guided Written Exposure Therapy for Complex Post-Traumatic Stress Disorder (GWE-C) among Chinese adolescents through a randomized controlled trial.
- Trial name
- NCT06931093
- Testing
- Group Guided Written Exposure Therapy for CPTSD (GWE-C), Supportive counselling
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University
Posttraumatic Stress Disorder
Efficacy of Internet-delivered Trauma-focused CBT for Young People With PTSD
The goal of this clinical trial is to compare therapist-guided internet delivered trauma-focused cognitive behavior therapy (CBT) to an active control condition comprising therapist-guided internet delivered cognitive behavioral…
- Trial name
- NCT06185244
- Testing
- Therapist-supported internet-delivered trauma-focused CBT, 12 weeks of therapist-supported internet-delivered psychoeducation and stress management/relaxation for both the youth and the care giver.
- Where
- Sweden
- Volunteers
- 240 people
- Sponsor
- Karolinska Institutet
ART, Hiv
Strengthening Families Living With HIV in Kenya
This study seeks to use a group-based microfinance/internal lending model to develop social capital among people with HIV in Kenya.
- Conditions
- ART, Hiv, Trust, Depression, Anxiety
- Trial name
- NCT04588883
- Testing
- Kuja Pamoja - HIV
- Where
- Kenya
- Volunteers
- 843 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Sleep Initiation and Maintenance Disorders, Anxiety
HIRREM Developmental Study
The purpose of this study is to explore the functional and physiological effects associated with the use of High-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM), as supplemental care, for symptoms of…
- Conditions
- Sleep Initiation and Maintenance Disorders, Anxiety, Post-Traumatic Stress Disorder, Hot Flashes
- Trial name
- NCT02709369
- Testing
- HIRREM
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Wake Forest University Health Sciences
Drug Use, Drug Abuse
Prevention of Post Sexual Assault Stress
The purpose of this study is to evaluate whether a brief intervention in video format, that includes education about reactions to assault and modeling of adaptive coping strategies, designed to reduce post assault drug use or…
- Conditions
- Drug Use, Drug Abuse, Posttraumatic Stress Disorder
- Trial name
- NCT01430624
- Testing
- PPRS, PIRI
- Where
- 2 sites in United States
- Volunteers
- 245 people
- Sponsor
- Medical University of South Carolina