Clinical trials: Oxygen Therapy
Heart Defects, Congenital, Adolescent
Rehabilitation of Adolescents and Young Adults With Congenital Heart Diseases
The investigators aim to measure the impact of a rehabilitation program in congenital cardiology in terms of health related quality of life.
- Conditions
- Heart Defects, Congenital, Adolescent, Young Adult
- Trial name
- QUALIREHAB (NCT03690518)
- Testing
- Cardiac rehabilitation
- Where
- 17 sites in France
- Volunteers
- 142 people
- Sponsor
- University Hospital, Montpellier
Rhabdomyolysis Linked to a Hereditary Disease of Metabolism
Evaluate the Effort Test as a Therapeutic Monitoring Tool in Acute Rhabdomyolyses
The prognosis of rhabdomyolyses related to hereditary diseases of metabolism is poor and treatments are only symptomatic. Rhabdomyolysis outbreaks are frequently precipitated by fever and fasting. They are unpredictable.
- Trial name
- EFFORHAB (NCT03802279)
- Testing
- Effort test, Functional tests on fibroblasts
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infant, Premature, Diseases, Premature Birth of Newborn
Elevated Midline Positioning During Diaper Change in Preterm Infants
Diaper changing is one of the most frequent routine care procedures in the neonatal intensive care unit (NICU) and is known to cause physiological instability and behavioral stress responses in preterm infants.
- Conditions
- Infant, Premature, Diseases, Premature Birth of Newborn, Pain
- Trial name
- NCT07865897
- Testing
- 30-Degree Elevated Midline Positioning, Standard Lateral Position Diaper Change
- Volunteers
- 80 people
- Sponsor
- Akdeniz University
Keratoconus
Evaluate the Safety and Feasibility of Same-Day Bilateral Epithelium-On Corneal Cross-Linking for Keratoconus
Clinical trial to evaluate the safety and feasibility of corneal cross-linking in both eyes on the same day in subjects with keratoconus.
- Trial name
- NCT07629557
- Testing
- Riboflavin Ophthalmic Solutions, UV-A Irradiation System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Glaukos Corporation
Oxygen Toxicity
Pulmonary Function After Hyperbaric Oxygen Therapy
Patients receiving hyperbaric oxygen therapy (HBOT) for any indication at the Hyperbaric Medicine Unit (University Health Network, Toronto, ON, Canada) from 2016-2021 were recruited to this prospective cohort study.
- Trial name
- NCT05088772
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Canada
- Volunteers
- 86 people
- Sponsor
- University of Toronto
Stem Cell Transplant Complications
Hyperbaric Oxygen Therapy for Hemorrhagic Cystitis Post HSCT
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a potentially curative therapy for many malignant or nonmalignant hematological diseases.
- Trial name
- NCT04502628
- Testing
- Hyperbaric oxygen therapy
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Shandong Provincial Hospital
Oxygen Deficiency
High-flow Nasal Cannula for Pediatric Anesthetic Induction
Endotracheal intubation in infants often involves more than one attempt, and oxygen desaturation is common. It is unclear whether nasal high-flow therapy, which extends the time to desaturation during elective intubation in…
- Trial name
- NCT05578131
- Testing
- high flow nasal oxygen, face mask
- Where
- South Korea
- Volunteers
- 132 people
- Sponsor
- Seoul National University Hospital
Newborn; Fit, Safety Issues
The Effects Of Safe Swadding On Newborns' Oxygen Saturation And Comfort Level
Objective: This study was conducted as a randomized controlled experimental study to determine the effects of safe swaddling on oxygen saturation and comfort in preterm newborns born between 30-36 weeks of gestation.
- Trial name
- NCT06900127
- Testing
- Safe Swaddling
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ayse Sonay Turkmen, Prof.Dr
Respiratory Distress Syndrome in Premature Infants, Very Low Birth Weight Baby
Inhaled Nitric Oxide (iNO) as an Adjunct to Neonatal Resuscitation
This study hopes to determine whether nitric oxide along with oxygen during the first 20 minutes of life in infants needing help with breathing will reduce the percentage and total exposure to oxygen during that time frame.
- Trial name
- iNO (NCT01220687)
- Testing
- iNO, Nitrogen
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- University of Oklahoma
Bronchiolitis
High-flow Nasal Oxygen Therapy in Hospitalized Infant With Moderate-to-severe Bronchiolitis
Over the last decade, high-flow nasal oxygen therapy (HFN) has emerged as a new method to provide respiratory support in children with moderate to severe bronchiolitis.
- Trial name
- BRONCHOPTI (NCT02856165)
- Testing
- High-flow nasal canula oxygen therapy, Low-flow oxygen therapy with standard nasal canula
- Where
- France
- Volunteers
- 268 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Child Autism
Hyperbaric Oxygen Treatment in Autism Spectrum Disorders
Hyperbaric oxygen therapy (HBOT) is part of a multidisciplinary therapeutic management of infant autism including psychotherapy, drug treatment and other therapeutics (speech therapy, occupational therapy restrictive diet ...).
- Trial name
- NCT04472780
- Testing
- Hyperbaric oxygen Therapy HBOT
- Where
- Tunisia
- Volunteers
- 80 people
- Sponsor
- General Administration of Military Health, Tunisia
Pain
Evaluation of Pain Intensity During Bone Marrow Biopsy Performed With Inhalation of Pre-Mixed 50 Per Cent Nitrous Oxide and Oxygen Mixture.
Bone marrow biopsy is a painful medical procedure often performed with local anesthetic. Therefore a double-blind, randomized, controlled trial was carried out in 330 adult patients who where referred for bone marrow biopsy and…
- Trial name
- NCT00219713
- Testing
- nitrous oxide and oxygen
- Where
- France
- Volunteers
- 280 people
- Sponsor
- Poitiers University Hospital
Vascular Disease, Critical Lower Limb Ischemia
Pilot Study of Hemospan® in Patients With Chronic Critical Limb Ischemia
The purpose of this study is to evaluate the effects of Hemospan infusion on vascular reactivity, regional perfusion and oxygenation of ischemic tissue in patients with chronic critical lower limb ischemia.
- Trial name
- NCT00633659
- Testing
- Hemospan (MP4OX), Voluven (HES 130/0.4)
- Where
- Sweden
- Volunteers
- 6 people
- Sponsor
- Sangart
Prematurity, Oxidative Injury
Comparison of Different Oxygen Delivery Strategies During Resuscitation of Babies
Preterm infants are born with immature lungs and often require help with breathing shortly after birth. This currently involves administering 100% oxygen.
- Conditions
- Prematurity, Oxidative Injury, Respiratory Distress
- Trial name
- NCT00356902
- Testing
- titration of oxygen during resuscitation
- Where
- Canada
- Volunteers
- 215 people
- Sponsor
- University of Calgary
COPD
Comparison of Anterior Chest Compression Assist and Abdominal Thrust Assist Technique COPD
A total 34 patients will be taken. 2 groups will be created to apply intervention. After signing consent form, 17 patients in group A will be given abdominal thrust assist technique and 17 patients in group B will be given…
- Trial name
- NCT05936801
- Testing
- Anterior Chest Compression technique, Abdominal Thrust Technique
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Pediatric Pneumonia
Effect of Nurse-Directed Therapeutic Positioning in Children With Pneumonia
Pneumonia is a common respiratory infection in children that may cause respiratory distress and impaired oxygenation. This quasi-experimental study aims to evaluate the effectiveness of nurse-directed therapeutic positioning on…
- Trial name
- NCT07913191
- Testing
- Nurse - Directed Side - Lying Positioning, Nurse - Directed Semi-fowler's positioning
- Volunteers
- 150 people
- Sponsor
- University of Baghdad
Ischemic Heart Disease, Coronary Artery Disease
Impact of Acute Normovolemic Hemodilution on Blood Viscosity
Acute normovolemic hemodilution (ANH) has long been employed for reducing allogenic blood transfusion for cardiac surgery, and hydroxyethyl starch has been used as an intravenous replacement fluid during ANH procedure.
- Trial name
- NCT03366753
- Testing
- acute normovolemic hemodilution, In-vitro hemodilution
- Where
- South Korea
- Volunteers
- 21 people
- Sponsor
- Konkuk University Medical Center
Hypoxic-ischemic Encephalopathy
Hyperbaric Oxygen Therapy Improves Outcome of Hypoxic-Ischemic Encephalopathy
The purpose of this study is to to evaluate the safety and efficacy of hyperbaric oxygen in term gestation newborn infants with hypoxic-ischemic encephalopathy..
- Trial name
- NCT02894866
- Testing
- hyperbaric oxygen
- Where
- 10 sites in China
- Volunteers
- 250 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Oxygen Consumption, Aortic Aneurysm
Study of Post-operative Oxygen Consumption Following Vascular Surgery
To define any changes in whole body oxygen consumption that occur following major vascular surgery (open aortic aneurysm surgery; endovascular aortic aneurysm repair; and infra-inguinal lower limb revascularisation procedures).
- Conditions
- Oxygen Consumption, Aortic Aneurysm, Peripheral Arterial Disease
- Trial name
- NCT01327820
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- NHS Lothian
Neonatal Respiratory Distress Related Conditions, Neonatal Respiratory Failure
Automated Versus Manual Control Of Oxygen For Preterm Infants On Continuous Positive Airway Pressure In Nigeria
One in ten babies are born preterm (<37 weeks gestation) globally. Complications of prematurity are the leading cause of death in children under 5 years, with the highest mortality rate in Sub-Saharan Africa (SSA).
- Conditions
- Neonatal Respiratory Distress Related Conditions, Neonatal Respiratory Failure, Prematurity, Oxygen Toxicity
- Trial name
- NCT05508308
- Testing
- OxyMate, Manual oxygen control
- Where
- 2 sites in Nigeria
- Volunteers
- 49 people
- Sponsor
- Murdoch Childrens Research Institute