Clinical trials: Neurophysiology
Children, Behavior
Role of Ethnicity and Environment on Regulation of Response Towards Sensory Stimulation in Children
Difference in autonomic nervous system processes across cultural and ethnic groups was suggested and autonomic regulation differentiation may occur even at an early age.
- Trial name
- NCT02878824
- Testing
- Ethnicity, Environment
- Where
- Hong Kong
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Autistic Disorder
Clinical and Neurophysiological Evolutions Through a Functional Rehabilitation of Social Communication in ASD
This study aims to identify clinical and biological markers which would allow to evaluate precisely the evolution of children with autism spectrum disorders throughout intervention.
- Trial name
- NCT02444117
- Testing
- functional rehabilitation of social communication
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Tours
Neurodevelopmental Disorders
Individual Neurophysiological Sensory Profiles in People With and Without Neurodevelopmental Disorders
The goal of this observational study is to evaluate intra-individual neurophysiological variability in children and adults with and without NeuroDevelopmental Disorders (NDD), for several sensory modalities and types of…
- Trial name
- SensAUry (NCT07542977)
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Adolescent Development, Stress
Neurophysiology, Estrogen, and Stress Exposure in the Emergence of Depression in Adolescent Girls
The prevalence of adolescent depression is steadily rising in the U.S., especially among adolescent girls. Currently 20% of adolescent girls experience major depression compared with 6% of boys (National Institute of Mental…
- Conditions
- Adolescent Development, Stress, Emotional Disturbances
- Trial name
- EVOLVE (NCT03450135)
- Testing
- Trier Social Stress Test, Emotional go/no-go task
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Healthy Subjects
The Impact of Pain Neuroscience Education on Physical Therapy Students' Knowledge, Attitudes, Beliefs, and Behaviors Towards Pain: A Randomized Controlled Trial
This study investigates the effect of pain neuroscience education (PNE) on pain knowledge, attitudes, beliefs and behaviors among undergraduate physiotherapy students in Jordan
- Trial name
- NCT06821022
- Testing
- Pain Neuroscience Education, Red Flags Education
- Where
- Jordan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Hashemite University
Infant Development
Assessment of Motor Development With a Wearable in Rural and Low-income Settings
The MaMa study aims to assess feasibility and validity of an infant wearable in a rural settings. Altogether N~100 infants will be recruited and measured multiple times at homes from age 6 months to age 18 months.
- Trial name
- MaMa (NCT05782673)
- Testing
- wearable MAIJU for motor assessment
- Where
- 4 sites in Finland, Malawi
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Tourette Syndrome, Tic Disorder
Sensorimotor and Psychosocial Trajectories in Adolescents With Tic Disorder
Individuals with tic disorders have lower quality of life, sensory and movement difficulties, and poorer mental, social, and physical health compared to the general population.
- Trial name
- NCT06576726
- Testing
- This study involves no intervention.
- Where
- United States
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Fear Avoidance
Knowledge, Attitudes, and Beliefs About Musculoskeletal Pain Among Primary Care Health Professionals in Spain.
Pain is influenced by psychological and emotional factors, and healthcare professionals may unintentionally contribute to chronic disability by reinforcing fear and limiting normal activity.
- Trial name
- CACDAPES (NCT06900231)
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Universitat de Lleida
Intracranial Hemorrhages, Prematurity
Neurophysiology and Anatomy of Severe Intraventricular Hemorrhage (IVH)
Currently, when premature infants develop severe intraventricular hemorrhage (IVH), a type of intracerebral bleed, there are no proven therapeutic interventions to prevent the devastating consequences of this event.
- Trial name
- NCT00817310
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Vanderbilt University
Obsessive Compulsive Disorder, Healthy
Cortical Excitability in Obsessive-Compulsive and Related Disorders
This study will use transcranial magnetic stimulation (TMS) to study the function of the cerebral cortex (outer layer of the brain) in people with obsessive compulsive disorder (OCD) and related disorders.
- Trial name
- NCT00029068
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Attention Deficit Hyperactivity Disorder, Dyslexia
Effects of Atomoxetine on Brain Activation During Attention & Reading Tasks in Participants With ADHD & Comorbid Dyslexia
This study will evaluate the effects of atomoxetine on brain activation during attention and reading tasks via functional Magnetic Resonance Imaging (fMRI) in participants ages 10 to 16 years old with ADHD and comorbid dyslexia
- Trial name
- NCT00716274
- Testing
- Atomoxetine
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Eli Lilly and Company
Diplegia, Spastic
Eye-Hand Coordination in Children With Spastic Diplegia
This study will examine how the brain controls eye-hand coordination (visuomotor skills) in children with spastic diplegia and will determine whether impairment of this skill is related to the learning difficulties in school that…
- Trial name
- NCT00024791
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Aphasia, Acquired
Clinic and Neurophysiology of Aphasia Treatment
In the planned study, clinical and electrophysiological features of aphasia recovery in stroke patients are investigated.
- Trial name
- AphasRehab (NCT05572385)
- Testing
- CIAT + Conventional neurorehabilitative therapy
- Volunteers
- 40 people
- Sponsor
- Klinik Bavaria
Surveys and Questionnaires, Child
Development and Clinimetric Properties of the Dutch Pediatric Neurophysiology of Pain Questionnaire in Healthy Children
The scientific objective of this research implies developing and examining the clinimetric properties of the Dutch Pediatric Neurophysiology of Pain Questionnaire (PedNPQ) in healthy children.
- Conditions
- Surveys and Questionnaires, Child, Pain, Knowledge
- Trial name
- NCT03162835
- Testing
- Pain Neuroscience Education
- Where
- Belgium
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Flatfoot, Flexible, Sports Physical Therapy
Neurophysiology-based Intervention of Foot Dysfunction in Sportive Children
The goal of the clinical trial study is to test the effect of the individual complex physiotherapy intervention program in the children actively playing soccer with flatfoot or valgus foot. The aims are: 1.
- Conditions
- Flatfoot, Flexible, Sports Physical Therapy, Child Development
- Trial name
- NCT05902091
- Testing
- Neurophysiology-based intervention
- Where
- Czechia
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Knowledge, Attitude
Pain Neurophysiology Education for Sport Therapy Students
The effect of a 70 minute Pain Neurophysiology Education session on Sport Therapy Students Knowledge, Attitudes and Clinical Behaviour Towards Athletes With Chronic Pain
- Conditions
- Knowledge, Attitude, Behavior
- Trial name
- NCT03002181
- Testing
- Education
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Teesside University
Usher Syndrome, Cochlear Implantation
Auditory Neural Function in Implanted Patients With Usher Syndrome
Usher syndrome (USH) causes extensive degeneration in the cochlear nerve (CN), especially in CN fibers innervating the base of the cochlea.
- Trial name
- NCT04906135
- Testing
- Experimental manipulation of stimulation parameters
- Where
- 4 sites in United States
- Volunteers
- 29 people
- Sponsor
- Ohio State University
Attention Deficit Hyperactivity Disorder (ADHD)
Train Your Brain and Exercise Your Heart? Advancing the Treatment for Attention Deficit Hyperactivity Disorder (ADHD)
Attention Deficit Hyperactivity Disorder (ADHD) is a developmental disorder that has a severe impact on a child's life and society. The core symptoms are attention problems, hyperactivity and impulsivity.
- Trial name
- NCT01363544
- Testing
- Neurofeedback, Exercise, methylphenidate
- Where
- 6 sites in Netherlands
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- R. van Mourik
Dystonia, Cerebral Palsy
Studying Childhood-Onset Hemidystonia
Background: Childhood-onset dystonia is caused by a brain injury. It causes muscle contractions and twisting movements that the person with dystonia cannot control.
- Trial name
- NCT01432899
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Multiple Sclerosis
The Efficacy of Pulse Therapy in Acute Relapse in Multiple Sclerosis Patients:
This work is aimed to assess the short term effect of pulse therapy on clinical and neurophysiological course before and after pulse therapy in order to understand the possible mechanism of action of steroid therapy on RRMS…
- Trial name
- NCT06280131
- Volunteers
- 30 people
- Sponsor
- Assiut University