Clinical trials: Lidocaine
Intubation; Difficult
Using Lignocaine Spray and Gel to Reduce the Pain Associated With Nasogastric Tube Insertion in Children
Nasogastric tube insertion is one of the most common invasive procedures performed in children's hospitals, and has long been recognised as one of the most traumatic and painful.
- Trial name
- NGTIPPS (NCT01075789)
- Testing
- Lignocaine
- Where
- Australia
- Volunteers
- 13 people
- Sponsor
- The University of Queensland
Pediatric Squint Surgeries
Comparing General Anesthesia With Single Injection Peribulbar Block With 3 Different Drugs
To compare the effect of the used local anesthetics in this study on decreasing the incidence of oculocardiac reflex . To evaluate the efficacy of Articaine 4 % , mepivacaine 3% and lidocaine 2% regarding post- operative…
- Trial name
- NCT05728151
- Testing
- Articaine and Epinephrine Only Product, levobupivacaine, mepivacaine
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- Research Institute of Ophthalmology, Egypt
Children, Only, Tonsillar Hypertrophy
Lidocaine Infusion for Pain Relief in Children Scheduled for Tonsillectomy and Adenoidectomy
Lidocaine is widely available and is a very commonly used local anesthetic. When administered intravenously, lidocaine infusions have anti-inflammatory effects and have significantly decreased the reliance on opioid use for…
- Conditions
- Children, Only, Tonsillar Hypertrophy, Adenoid Hypertrophy
- Trial name
- NCT03902314
- Testing
- Lidocaine Iv, Saline Solution
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Rhode Island Hospital
Anesthesia, Local, Pain
Clinical Trial Comparing Effectiveness of Buffered Versus Unbuffered Local Anesthetic in Children Ages 10-12 Years
Local anesthesia is an integral part of clinical pediatric dental practice, but it has challenges. It can be uncomfortable for children, and the risk of adverse events limits how much is used.
- Trial name
- NCT03562481
- Testing
- 1% Buffered Lidocaine 1:100,000 Epinephrine, 2% Unbuffered Lidocaine 1:100,000 Epinephrine
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Pain
Evaluation of Pain Intensity During Bone Marrow Biopsy Performed With Inhalation of Pre-Mixed 50 Per Cent Nitrous Oxide and Oxygen Mixture.
Bone marrow biopsy is a painful medical procedure often performed with local anesthetic. Therefore a double-blind, randomized, controlled trial was carried out in 330 adult patients who where referred for bone marrow biopsy and…
- Trial name
- NCT00219713
- Testing
- nitrous oxide and oxygen
- Where
- France
- Volunteers
- 280 people
- Sponsor
- Poitiers University Hospital
"Lost" IUD
Anesthetic Efficacy of Intrauterine Lidocaine for Removal of a "Lost" Intrauterine Device
Objective: To evaluate the efficacy of intrauterine lidocaine instillation in reducing patient discomfort during the removal of a "lost" intrauterine device (IUD).
- Trial name
- NCT00308841
- Testing
- Lidocaine (drug)
- Where
- Turkey (Türkiye)
- Sponsor
- Suleyman Demirel University
Anesthesia
Needle-Free Lidocaine Injection vs Traditional Local Anesthesia in Infant Lumbar Puncture
We hypothesize that the J-Tip needle-free jet-injection system offers comparable pain control and greater provider satisfaction due to its less invasive nature compared to traditional needle infiltration of 1% lidocaine in…
- Trial name
- NCT06552351
- Testing
- Needle-Free Jet Injection of 1 % lidocaine, traditional needle infiltration of 1% lidocaine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Oklahoma
ADHD
Observational Study to Assess the Frequency of Lidocaine Ineffectiveness in Hard-to-treat ADHD
This work will assess the prevalence in hard-to-treat ADHD of the ineffectiveness of the anesthetic Lidocaine.
- Trial name
- NCT04167189
- Testing
- Lidocaine gel
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- PhenoSolve, LLC
Surgical Procedure, Unspecified
Recovery After Total Intravenous Anesthesia With Ketofol Versus Mixture of Ketofol and Lidocaine for Short Pediatric Surgery
Two hundred children aged 1-12 years undergoing short surgery will be randomized into two groups. Ketofol will be used for induction and maintenance of anesthesia in group l. .Ketofol with lidocaine will be prepared for group ll.
- Trial name
- Lidoketofol (NCT04467424)
- Testing
- ketamine, propofol, ketamine, propofol, lidocaine
- Where
- Croatia
- Volunteers
- 200 people
- Sponsor
- University Hospital of Split
Postpartum
Lidocaine-prilocaine Cream Versus Rectal Meloxicam on Relief of Post-episiotomy Pain
Postpartum perineal pain is a very common complaint. It can have negative consequences for mother and child including disability in daily functioning for the mother; for example, it can interfere in taking care of her infant and…
- Trial name
- NCT03146000
- Testing
- lidocaine-prilocaine cream, meloxicam rectal suppository
- Where
- Egypt
- Volunteers
- 190 people
- Sponsor
- Assiut University
Pain
The Effect of Pretreatment With Intravenous Lidocaine for Intravenous Contrast:
Intravenous contrast media is commonly used for CT scans for improved image clarity in pediatric emergency medicine. Children who feel discomfort during the administration of IV contrast media may not remain still during the CT…
- Trial name
- NCT05143489
- Testing
- Preservative Free Lidocaine, Saline
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Antonios Likourezos
Anesthesia, Local
Lidocaine Administration Using STAR Particles
This study is being done to answer the question: Do STAR particles (tiny pieces of ceramic with small spikes) help numbing gel (a gel that helps you feel less pain) work more quickly to provide local anesthesia or numbing in a…
- Trial name
- NCT06034340
- Testing
- LET Gel after STAR Particle Application (Right or Left Arm), LET Gel Application without STAR Particle Application (Contralateral Arm)
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Emory University
Contraception
Comparative Safety and Efficacy of Vaginal Dinoprostone Versus Lidocaine-prilocaine Cream in Copper IUD Insertion
the aim of the present study is to Compare Safety and Efficacy of Vaginal dinoprostone Versus Lidocaine-prilocaine Cream in copper IUD Insertion in nulliparous women: a randomized controlled trial
- Trial name
- NCT04340778
- Testing
- vaginal dinoprostone, Lidocaine-prilocaine Cream
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Operative Pain, Postoperative Hemorrhage
Efficacy of Local Infiltration of Tranexamic Acid and Lidocaine in Tonsillar Bed on Postoperative Bleeding and Pain During Tonsillectomy Surgery: Prospective, Randomized, Control Study
All anesthetic techniques aim to lessen intra-operative surgical site bleeding because it is a major problem and does not help with precision, surgery time, or postoperative wound healing.
- Trial name
- NCT05817474
- Testing
- lidocaine (2 %) 2 ml and tranexamic acid
- Where
- Egypt
- Volunteers
- 94 people
- Sponsor
- mohamed
Pain, Anxiety
Vibrating, Cold Device for Pediatric Intravenous (IV) Cannulation Pain Relief
The purpose of this study is to test the effectiveness of Buzzy®, a battery-powered reusable device that provides cold and vibration, in reducing the pain associated with intravenous (IV) cannulation.
- Trial name
- NCT01394250
- Testing
- Buzzy, Topical Lidocaine 4% Cream
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Anesthesia, Spinal, Pain
Comparison of Two Analgesic Pretreatment Techniques Before Spinal Needle Insertion for Pain Reduction and Maternal Satisfaction Level Assessment in Women Undergoing LSCS.
Nowadays lower segment cesarean sections are preferably carried out under regional anesthesia due to multiple advantages. Local infiltration of lidocaine or any other anesthetic is used before lumber puncture in many centers to…
- Conditions
- Anesthesia, Spinal, Pain, Pregnancy, Cesarean Section
- Trial name
- NCT04050059
- Testing
- EMLA cream, 2% lidocaine
- Where
- Pakistan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Pediatric, Elective
Laryngeal Mask Airways Are Supraglottic Devices Used to Maintain Airway Patency During Anesthesia and in Difficult Airways. IV Dexmedetomidine Improves LMA Insertion Success and Decreases Coughing, While IV Lidocaine Decreases Postoperative Cough.
Laryngeal Mask Airways Are Supraglottic Devices Used to Maintain Airway Patency During Anesthesia and in Difficult Airways. LMA may help in reducing postoperative pulmonary complications.
- Conditions
- Pediatric, Elective, Surgery in Early Childhood
- Trial name
- DEX LMA (NCT07562308)
- Testing
- Dexamedomedine, Lidocaine (drug)
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Dyspepsia, Malabsorption Syndrome
Evaluation of Topical Lidocaine Spray as Adjuvant to Upper Gastrointestinal Endoscopy in Children
There is some controversy in the medical literature regarding the effectiveness of topical lidocaine in children as an adjuvant drug to upper gastrointestinal endoscopy.
- Conditions
- Dyspepsia, Malabsorption Syndrome, Gastroesophageal Reflux Disease, Abdominal Pain
- Trial name
- NCT00521703
- Testing
- Lidocaine, Tannic acid
- Where
- Brazil
- Volunteers
- 78 people
- Sponsor
- Hospital Infantil Cândido Fontoura
Pain
Self-administered Intravaginal 2% Lidocaine Gel Prior to Intrauterine Device Insertion in Nulliparous Women
This study is designed to evaluate if self-inserted intravaginal 2% lidocaine gel is effective at decreasing pain during intrauterine device insertion in nulliparous women.
- Trial name
- LIVIIN (NCT01534520)
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pain Intensity Assessment, Pain Management
Studying Warmed Lidocaine for Increased Analgesic Effect During Intravitreal Injections
Investigating whether warmed lidocaine increases analgesic effect for intravitreal injections
- Trial name
- WarmLido (NCT06962709)
- Testing
- Warmed lidocaine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Missouri-Columbia