Clinical trials: Dehiscence
Bladder Exstrophy
Early Versus Delayed Closure of Bladder Exstrophy in Female Patients
This study compared two timings for primary single-stage surgery in female newborns with classic bladder exstrophy. Participants were randomly assigned to surgery within 72 hours of birth or at 6 to 12 weeks of age.
- Trial name
- NCT07794540
- Testing
- Early Primary Single-Stage Closure, Delayed Primary Single-Stage Closure
- Where
- Pakistan
- Volunteers
- 124 people
- Sponsor
- Khyber Teaching Hospital
Laceration, Skin Wound
Comparison of microMend® Devices to Sutures in Closing Lacerations in Children
This study will gather information on the use of microMend® to repair lacerations in children and compare the efficacy of microMend® to sutures for laceration repair.
- Conditions
- Laceration, Skin Wound, Wound Heal
- Trial name
- NCT04557761
- Testing
- microMend®, Closure with Sutures
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospital of Orange County
Hypospadias Repair
Hemostasis During Hypospadias Surgery
A comparison between the two hemostatic methods of hypospadias repairing operation, in terms of early and mid-term (up to 6 months) failure rate (wound dehiscence and urethral stricture needing reoperation) between the two…
- Trial name
- NCT02268019
- Testing
- tourniquet application, epinephrine injection
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Isfahan University of Medical Sciences
Hypospadias
Effect of Caudal and Penile Block on Hypospadias Repair Complications
Hypospadias is one of the most common genitourinary (GU) malformations, seen in approximately 1 of 250 male live births. Common methods of local anesthesia administration for hypospadias surgery include caudal and dorsal penile…
- Trial name
- NCT02851290
- Testing
- Caudal block anesthesia, Dorsal penile nerve block anesthesia
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Baylor College of Medicine
Hypospadias
Local Oestrogen Versus Placebo as Preoperative Treatment in Patients With Severe Hypospadias: Effects on Post-operative Complications
Hypospadias is a congenital abnormality of the penis that is caused by incomplete development of the anterior urethra. This pathology is one of the most common genital anomalies in paediatric urology .The incidence is reported to…
- Trial name
- HYPOSPADES (NCT01370798)
- Testing
- promestriene, Urethroplasty, Wrist X ray
- Where
- 4 sites in France
- Volunteers
- 244 people
- Sponsor
- Hospices Civils de Lyon
Brain Neoplasms
Dexmedetomidine and Intelligence Development in Pediatric Patients Undergoing Craniotomy
The purpose of this randomized, double-blind and placebo-controlled pilot study is to investigate whether dexmedetomidine when used as an adjuvant to general anesthesia can decrease the harmful effects of anesthesia and surgery…
- Trial name
- NCT02810899
- Testing
- dexmedetomidine, normal saline
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University First Hospital
Wound; Head, Multiple, Wound; Head, Scalp
Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection
- Trial name
- FTFDT3 (NCT03872544)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Wound Infection, Wound Dehiscence
Honey Dressing - A Preventive Procedure for Post-Surgical Site Infection.
The goal of this clinical trial is to compare the wound healing in the participants who underwent the clean surgical procedure, by applying honey dressing and common Iodine solution dressing, participants will have no other…
- Conditions
- Wound Infection, Wound Dehiscence, Wound Bleeding, Wound Surgical
- Trial name
- NCT06220344
- Testing
- Honey Dressing, Iodine Dressing
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- HITEC-Institute of Medical Sciences
Cerebral Palsy
Knotless Versus Conventional Sutures for Wound Closure in Cerebral Palsy Multilevel Surgery
This study compares two standard ways of closing surgical incisions in children and adults with cerebral palsy who are having multilevel surgery on both legs (single-event multilevel surgery, or SEMLS).
- Trial name
- NCT07880197
- Testing
- Knotless barbed suture, Conventional suture
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Los Angeles
Laceration of Skin, Injury Skin
Assessment of DAFILON® Suture Material for Skin Closure
In this non-interventional study (NIS) a polyamide non-absorbable suture (Dafilon®) will be evaluated for skin closure in adult and pediatric patients.
- Trial name
- SKINDA (NCT04617041)
- Where
- 2 sites in Germany, Spain
- Volunteers
- 115 people
- Sponsor
- Aesculap AG
Cesarean Wound; Dehiscence
Removal Versus Non Removal of Ceserean Section Scar .
EXCISION of cs section skin scar and subcutaneous release versus non removal in repeated cs .aRandomized controlled trial .
- Trial name
- cs (NCT05150678)
- Testing
- removal of ceserean section scar, non removal of cesearean section scar
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Assiut University
Disruption or Dehiscence of Closure of Skull or Craniotomy
Incidence of Pain After Craniotomy in Children
The primary objective is to assess the incidence and severity of pain after major craniotomy in paediatric patients (from 1 month to 10 years of age).
- Trial name
- Brainpain (NCT01142830)
- Where
- 8 sites in Italy
- Volunteers
- 218 people
- Sponsor
- San Gerardo Hospital
Wounds and Injuries, Wound Infection
Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries
- Trial name
- FTFDT2 (NCT03880188)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Pilonidal Sinus
Pilonidal Sinus Disease: Preliminare Study
Pilonidal disease is morbid condition of young productive population, that could impair quality of life with high cost for health care system.
- Trial name
- NCT03764657
- Testing
- In "hot" group 16 patients were treated by diathermy in "Cold", in "Cold" group 13 patients were treated by scalpel.
- Where
- Italy
- Volunteers
- 29 people
- Sponsor
- Ospedale di Cavalese
Bone Loss, Tooth Movement
The Introduction of a Novel PAOO Technique
The aim of this study is to evaluate in a prospective, randomized, controlled clinical trail the effectiveness of preorthodontic piezotomy combined with a buccal bone augmentation (in other name periodontlly accelerated…
- Trial name
- NCT05264480
- Testing
- Bone augmentation with minimally invasive corticotomy (piezotomy), Bone augmentation without corticotomy
- Where
- Hungary
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Postoperative Wound Breakdown
Fascial Dehiscence and Mortality
Nationwide cohort study on short- and long-term mortality of patients with and without postoperative fascial dehiscence. The cohort will be comprised of patient undergoing open colonic resection for colonic cancer registered in…
- Trial name
- NCT03008265
- Testing
- Postoperative fascial dehiscence
- Where
- Denmark
- Volunteers
- 9,000 people
- Sponsor
- Kristian Kiim Jensen
Alveolar Buccal Bone Dehiscences, Socket Type 3 Subclass B
Evaluation Of The Success Rate of NOVAMag® SHIELD
This study hypothesizes that the SHIELD technique, when combined with a suitable bone graft material, enables successful immediate implant placement in Type 3 extraction sockets with buccal bone dehiscence, regardless of the…
- Conditions
- Alveolar Buccal Bone Dehiscences, Socket Type 3 Subclass B, Socket Type 3 Subclass C
- Trial name
- NOVASHIELD-RCT (NCT07533110)
- Testing
- SHIELD technique with NOVAMag membrane
- Where
- Portugal
- Volunteers
- 40 people
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Cleft Lip, Cleft Palate +/- Lip
Comparative Study of Regional Nerve Blocks in Primary Cleft Palate Repair
This study will evaluate whether adding a suprazygomatic maxillary nerve block to the standard palatal nerve block improves pain control after cleft palate repair surgery in children.
- Conditions
- Cleft Lip, Cleft Palate +/- Lip, Pain Management, Wound Dehiscence, Surgical
- Trial name
- NCT07892963
- Testing
- Palatal Nerve Block, Suprazygomatic Maxillary Nerve Block
- Volunteers
- 144 people
- Sponsor
- Children's National Research Institute
Wound Dehiscence, Incision
Pediatric Post-operative Abdominal Wound Dehiscence in Association With Midline vs Other Incisions: A Prospective Cohort Study
This study is designed to see different abdominal incisions complication among neonates, infants and children and to find risk factors for developing wound dehiscence
- Trial name
- NCT05963477
- Testing
- laparatomy
- Where
- Afghanistan
- Volunteers
- 270 people
- Sponsor
- French Medical Institute for Mothers and Children
Hypospadias
Caudal vs Local Anesthesia in Hypospadias
Hypospadias is one of the most common congenital malformations of the genitalia in boys, and is typically managed by surgical intervention.
- Trial name
- CLASH (NCT02512887)
- Testing
- Caudal Block Anesthesia, Dorsal Penile Block Anesthesia
- Where
- 4 sites in Canada
- Volunteers
- 224 people
- Sponsor
- McMaster University