Clinical trials: Dehiscence
Surgical Wound, Wound Dehiscence, Surgical
Prophylactic Negative Pressure Wound Therapy for High Risk Laparotomy Wounds. A Randomized Prospective Clinical Trial.
Negative pressure wound closure technique (NPWT) has been widely introduced in different clinical settings. Most of the studies report it as an effective and cost-effective method to treat complicated surgical wounds or even open…
- Conditions
- Surgical Wound, Wound Dehiscence, Surgical, Surgical Site Infection, Dehiscence of Internal Surgical Wound
- Trial name
- NCT03716687
- Testing
- Prophylactic negative pressure wound dressing after laparotomy
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- St. Borbala Hospital
Cesarean Section; Dehiscence
Preemptive Analgesia With Intravenous Paracetamol for Post-cesarean Section Pain Control
The investigators designed a prospective randomized study to investigate the efficacy of intravenous (IV) preemptive paracetamol on postoperative pain scores, patient satisfaction, total morfin consumption and the incidence of…
- Trial name
- NCT02369133
- Testing
- paracetamol
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Baskent University
Sternal Dehiscence, Sternal Infection
Improvement of Hemostasis Techniques After Median Sternotomy
The purpose of this study is to compare 2 different hemostatic agents (Bonewax and Ostene)to a control group with regards to bleeding, bone healing, pain and infection in a patient group all undergoing median sternotomy.
- Conditions
- Sternal Dehiscence, Sternal Infection, Sternal Pain
- Trial name
- NCT01134471
- Testing
- Ostene, Bonewax
- Where
- Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Badly Decayed Anterior Maxillary Teeth
Immediate Implant Placement With Immediate Provisionalization Into Extraction Sockets With Labial Plate Dehiscence Defects Within the Maxillary Esthetic Zone
Immediate tooth replacement with implants into extraction sockets has become a common clinical procedure regarding implant survival, osseointegration and esthetics.
- Trial name
- NCT03676244
- Testing
- immediate implant in defected anterior maxillary esthetic zone
- Volunteers
- 15 people
- Sponsor
- Cairo University
Surgical Wound Dehiscence, Cutis Laxa
Use of 2-octyl-cyanoacrylate Together With a Self-adhering Mesh
The investigators prospectively studied the results of wound closure after abdominoplasty with randomized use of PrineoTM and conventional suturing to assess the possible difference in outcome between these two methods.Follow-up…
- Conditions
- Surgical Wound Dehiscence, Cutis Laxa, Wound of Skin
- Trial name
- NCT01658163
- Volunteers
- 2 people
- Sponsor
- Medical University of Graz
Surgical Site Infection, Length of Stay
Prevena to Prevent Surgical Site Infection After Emergency Abdominal Laparotomy
Post-operative wound complications in abdominal surgery have a major impact on patient outcomes and the real impact of Closed incision negative pressure therapy (CINVt) is not clear in the literature moreover concerning its…
- Conditions
- Surgical Site Infection, Length of Stay, Seroma, Hematoma
- Trial name
- CiPNT/SSI (NCT04496180)
- Testing
- Closed incision negative pressure therapy versus standard dressing after emergency abdominal laparotomies
- Volunteers
- 334 people
- Sponsor
- University Hospital, Geneva
Colon Cancer, Rectal Cancer
Pilot Study Evaluating the Efficacy of AlloMEM After Loop Ileostomy
The objective of this study is to investigate whether the use of Human Peritoneal Membrane (HPM) in a temporary loop ileostomy is beneficial to patients.
- Trial name
- AlloMem (NCT01113736)
- Testing
- AlloMEM™
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Reproductive Issues, Cesarean Section; Dehiscence
Hysteroscopic Isthmocele Repair on IVF Outcome
Hysteroscopic Isthmocele repair on IVF outcome It aims to assesse the efficacy of Hysteroscopic CS scar defect repair on the clinical pregnancy rate after embryo transfer.
- Conditions
- Reproductive Issues, Cesarean Section; Dehiscence, Intrauterine Disorder
- Trial name
- NCT05590104
- Testing
- Hysteroscopic CS scar defect repair
- Where
- 2 sites in United Arab Emirates
- Volunteers
- 50 people
- Sponsor
- HealthPlus Fertility Center
Obstetric Trauma, Infections
Oral Antibiotics After Obstetric Perineal Tear
The purpose of this study is to investigate if 3 dose of oral antibiotics administrated the first day after a vaginal delivery with a second degree obstetric tear will decrease the risk of infection and/or wound dehiscence…
- Conditions
- Obstetric Trauma, Infections, Wound Dehiscence
- Trial name
- REPAIR (NCT05830162)
- Testing
- Bioclavid (Amoxicillin and Clavulanic acid)
- Where
- Denmark
- Volunteers
- 442 people
- Sponsor
- Hanna Jangö
Colo-rectal Anastomosis Dehiscence
The Role of Ghost Ileostomy in Laparoscopic Rectal Resection
To evaluate if the Ghost Ileostomy is really advantageous in laparoscopy we conducted a prospective randomized controlled study comparing 2 groups of patients undergoing anterior resection of the rectum laparoscopically.
- Trial name
- GILRR (NCT01861379)
- Testing
- Ghost Ileostomy
- Volunteers
- 107 people
- Sponsor
- University of Roma La Sapienza
Wounds and Injuries, Wound Infection
Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries
- Trial name
- FTFDT2 (NCT03880188)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Cesarean Section; Dehiscence, Breast Feeding
Technology-Based Breastfeeding Training After Cesarean
Aim: The aim of this study was to determine the effect of breastfeeding training given with virtual reality (VR) to postpartum primiparous mothers on breastfeeding success and breastfeeding self-efficacy.
- Conditions
- Cesarean Section; Dehiscence, Breast Feeding, Self Efficacy
- Trial name
- NCT06256822
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ordu University
Vaginal Cuff Complications
Oxidized Regenerated Cellulose to Decrease Vaginal Cuff Complications
The goal of the investigators study is to determine whether the use of oxidized regenerated cellulose reduces the risk of vaginal cuff cellulitis, pelvic abscess, or vaginal cuff dehiscence in patients undergoing laparoscopic…
- Trial name
- NCT01584128
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Dehiscence Wound
Efficacy Evaluation of ActiGraft in Secondary Closure of Abdominal Surgical Wound Dehiscence
This is a prospective, single arm study, consisting of 20 women with abdominal surgical wound dehiscence that requires secondary closure.
- Trial name
- NCT04899466
- Testing
- ActiGraft
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- RedDress Ltd.
Breast Cancer, Surgical Site Infection
NPWT for Abdominal Incisions in DIEP Reconstructions: A RCT
The current study is a single center randomized control trial that will examine the effect of closed incision negative pressure wound therapy (ciNPT) versus conventional dressing on abdominal incision in a deep inferior…
- Conditions
- Breast Cancer, Surgical Site Infection, Wound Dehiscence
- Trial name
- NPWTinDIEP (NCT05338281)
- Testing
- Negative Pressure Wound Therapy
- Where
- Canada
- Sponsor
- Western University, Canada
Cesarean Section; Dehiscence, Cesarean Section Complications
Lower Uterine Segment Thickness and Term Pain,Previous Cesarean Section
the purpose of the researchers; The aim of this study is to evaluate the consistency of niche dimensions measured by ultrasonography with visual measurement of the surgeon during the operation of the patient when presenting with…
- Trial name
- NCT04070118
- Testing
- Measure niche thickness with ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Cutaneous Ulcer, Diabetic Ulcer
Dermacyte® Liquid for Treatment of Cutaneous Ulcers and Wounds
The objective of this study is to make Dermacyte Liquid available on an expanded access basis to treat cutaneous ulcers and wounds refractory to initial treatment or that do not have adequate alternative treatments.
- Conditions
- Cutaneous Ulcer, Diabetic Ulcer, Surgical Wound Dehiscence, Burns - Multiple
- Trial name
- NCT06730022
- Testing
- MTX-001 (Dermacyte Liquid)
- Where
- United States
- Sponsor
- Merakris Therapeutics
Superior Semicircular Canal Dehiscence
Electro-physiological Findings and Symptoms Severity in Superior Canal Dehiscence
This research aims at assessing the validity of three different electro-physiological tests (Vestibular Evoked Myogenic Potentials, WideBand Tympanometry, Electrocochleography) used in the investigation of the symptoms severity…
- Trial name
- INTEX-DEHI (NCT06170398)
- Testing
- Wideband tympanometry, Electrocochleography, Vestibular Evoked Myogenic potentials
- Where
- France
- Volunteers
- 115 people
- Sponsor
- University Hospital, Toulouse
Cesarean Section; Dehiscence
Ultrasound Based Study For Niche Development In The Uterine Cesarean Section Scar
The aim of this study is to evaluate different factors affecting niche development in the uterine cesarean section scar in women enrolled 3 to 6 months after cesarean delivery using both TVS and SIS.
- Trial name
- NCT03859258
- Testing
- Transvaginal sonography
- Where
- Egypt
- Volunteers
- 221 people
- Sponsor
- Cairo University
Diabetic Foot Ulcers
Investigation of Subatmospheric Pressure Dressing on Pressure Ulcer Healing
Many spinal cord injury (SCI) and otherwise debilitated patients develop pressure ulcers over the course of their injury or disease.
- Trial name
- NCT00011531
- Testing
- Prevention of Pressure Ulcers
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- US Department of Veterans Affairs