Clinical trials: D-dimer
Deep Vein Thrombosis
D-Dimer Vs Serial Compression Ultrasound Study
To determine whether d-dimer testing can be used to simplify and reduce the costs of the diagnostic approach to patients with clinically suspected deep vein thrombosis
- Trial name
- NCT00182351
- Testing
- D-dimer, Serial Compression Ultrasound
- Where
- 3 sites in Canada
- Volunteers
- 810 people
- Sponsor
- Hamilton Health Sciences Corporation
Pregnancy, Deep Vein Thrombosis
Safely Ruling Out Deep Vein Thrombosis in Pregnancy With the LEFt Clinical Decision Rule and D-Dimer
This is prospective cohort study in pregnant women who present with signs and symptoms of possible deep vein thrombosis (DVT). All patients will have the same method of assessment of their DVT symptoms (the LEFt clinical decision…
- Trial name
- LEaD (NCT02507180)
- Testing
- LEFt clinical decision rule
- Where
- 12 sites in United States, Canada and 2 more
- Volunteers
- 366 people
- Sponsor
- Ottawa Hospital Research Institute
Deep Vein Thrombosis, Pulmonary Embolism
D-Dimer and IPG for Recurrent Thrombosis (DIRECT)
To simplify and improve the diagnostic approach to patients with clinically suspected recurrent DVT by determining whether the results of the combination of IPG and d-dimer testing, using a whole blood agglutination assay, can be…
- Trial name
- NCT00182247
- Testing
- venogram
- Where
- 8 sites in Canada, Italy
- Volunteers
- 600 people
- Sponsor
- Hamilton Health Sciences Corporation
COVID-19
Serum Level of Ferritin and D-dimer and the Severity of (COVID 19) Infection
Many laboratory biomarkers were used for diagnosis of COVID-19 infection; however, their accuracy to assess the severity and prognosis are still to be evaluated.
- Trial name
- NCT05672810
- Testing
- serum level of Ferritin and D-dimer
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Ain Shams University
Deep Vein Thrombosis
D-dimer and Pre-test Clinical Probability Score in Cancer Patients With Suspected Deep Vein Thrombosis of the Legs
Patients with cancer have a high risk of deep vein thrombosis which often develops in the veins of the lower limbs. The initial evaluation of clinically suspected deep vein thrombosis includes the estimation of the clinical…
- Trial name
- NCT02341937
- Testing
- Diagnostic tests for suspected deep vein thrombosis
- Where
- Italy
- Volunteers
- 239 people
- Sponsor
- G. d'Annunzio University
Idiopathic Intracranial Hypertension
Quantitative D-dimer Level and Anticoagulant Therapy in Idiopathic Intracranial Hypertension
Idiopathic intracranial hypertension (IIH) is a syndrome characterized by elevated intracranial pressure (ICP) of unknown etiology.
- Trial name
- NCT03963336
- Testing
- LMWH, acetazolamide
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Cerebral Venous Thrombosis
Thrombin Generation and Thrombus Degradation in Cerebral Venous Thrombosis : Clinical and Radiological Correlations
Cerebral venous thrombosis is considered as a rare type of stroke with an annual incidence of 3 to 4 per million people. It occurs generally in young patients (mean age of occurrence = 40 years) and principally in young females…
- Trial name
- PHRC-TVC (NCT02013635)
- Testing
- Blood samples, Neuroimaging, Clinical assessments
- Where
- 36 sites in France
- Volunteers
- 232 people
- Sponsor
- University Hospital, Rouen
Stroke Code, Large Vessel Occlusion
Evaluation of a Point-of-care Lateral Flow Assay in Glial Fibrillary Acidic Protein (GFAP) and D-dimer in Diagnosis of Large Vessel Occlusion Acute Ischemic Stroke in a Pediatric Hospital
The goal of this study is to test the efficacy of a rapid bedside blood test in determining if a stroke is happening in children who present to the emergency department with stroke symptoms.
- Conditions
- Stroke Code, Large Vessel Occlusion, Acute Ischemic Stroke
- Trial name
- NCT07474675
- Testing
- Point of Care Rapid Assay
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Boston Children's Hospital
Deep Venous Thrombosis
Measurement of D-Dimer Levels in Patients With Confirmed Deep Vein Thrombosis
Measurement of D-Di (D-Dimer) levels using the in-vitro diagnostic reagent STA® - Liatest® D-Di and STA® - Liatest® D-Di PLUS in plasma samples from patients diagnosed with Deep Vein Thrombosis (DVT) Data from this study may be…
- Trial name
- NCT02078154
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Diagnostica Stago
Adnexal Torsion
Role of Preoperative D-dimer Levels in the Diagnosis of Adnexal Torsion
Adnexal torsion is the fifth most common gynecologic emergency. Thirty percent of all cases of adnexal torsion occur in females younger than 20 years.
- Trial name
- NCT06324565
- Testing
- D-Dimer test
- Where
- 9 sites in Austria, Italy and 1 more
- Volunteers
- 130 people
- Sponsor
- IRCCS Burlo Garofolo
Suspected Pulmonary Embolism, Deep Venous Thrombosis
Canadian Pulmonary Embolism Diagnosis Study (CANPEDS)
The main objective of the trial is to determine whether D-dimer testing combined with assessment of Pre-Test-Probability (using a standardized clinical model) can be used to markedly simplify the diagnostic process for PE.
- Trial name
- NCT00182546
- Testing
- Two diagnostic management strategies
- Where
- 7 sites in Canada
- Volunteers
- 1,126 people
- Sponsor
- Hamilton Health Sciences Corporation
COVID-19
BNP, Serum Troponin and D-dimer as Risk Factors in Patients With COVID-19
To evaluate the role of N terminal pro B type natriuretic peptide (NTproBNP), D-Dimer, and Troponin - I as risk factors in COVID-19 patients and to correlate these markers with in-hospital death in patients with COVID-19
- Trial name
- NCT04433026
- Testing
- N terminal pro B type natriuretic peptide (NTproBNP), D-Dimer, and serum Tropinin - I
- Volunteers
- 90 people
- Sponsor
- Assiut University
Deep Venous Thrombosis, Pulmonary Embolism
STA®-Liatest®D-Di-Exclusion of Venous Thromboembolism
The purpose of this study is to demonstrate the ability of STA® Liatest® D-Di combined with a clinical pretest probability (PTP) to safely exclude pulmonary embolism (PE) or Deep Venous Thrombosis (DVT) in a 3 month follow-up.
- Conditions
- Deep Venous Thrombosis, Pulmonary Embolism, D-dimer
- Trial name
- DiET (NCT01221805)
- Where
- 18 sites in United States, Canada and 3 more
- Volunteers
- 2,040 people
- Sponsor
- Diagnostica Stago
Ductus Arteriosus, Patent
Ductus Arteriosus Closure and D-Dimer and Fibrinogen Levels
The aim of this study is to investigate whether there is a relationship between echocardiographic measurements regarding closure of PDA and serum D-Dimer and Fibrinogen levels in premature infants born before 32nd gestational…
- Trial name
- NCT04508036
- Testing
- Withdrawal of blood samples for D-Dimer, Withdrawal of blood samples for Fibrinogen, Echocardiographic Examination
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Critical Illness, Pneumonia, Viral
D-Dimer as Predictor of Disease Outcome in Intensive Care Unit in COVID-19m Patients
Evaluating value of D-Dimer blood level of icu admitted patients on admission and 48 hours later as outcome predictor in SARS.COV.2 patients.
- Trial name
- COVID-19 (NCT05279469)
- Testing
- no intervention, just observational for D-Dimer level in blood
- Where
- 2 sites in Egypt
- Volunteers
- 465 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pneumonia
Observation and Treatment of Pulmonary Microthrombosis in Childhood Pneumonia With Elevated D-dimer
Objective 1. Master the clinical feathers, imaging features and laboratory diagnosis characteristics and economic costs of children pneumonia with higher D-dimer: 1.
- Trial name
- NCT04778917
- Testing
- Low-Molecular-Weight Heparins Calcium Injection
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Capital Institute of Pediatrics, China
Acute Leukemia
Assessment of Antithrombin III, Protein C, Protein S and D-dimer in Acute Leukemia
The goal of this observational study is to evaluate the levels of Antithrombin III, Protein C, Protein S, and D-dimer in patients with Acute Leukemia (Acute Lymphoblastic Leukemia (ALL) and Acute Myeloid Leukemia (AML)).
- Trial name
- NCT07036809
- Testing
- Antithrombin III, Protein C, Protein S
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Muhamed Ahmed Abdelmoaty Muhamed Alhagrasy
Thrombosis, Deep Venous Thrombosis
Venous Thromboembolism and Haemostatic Disturbances in Patients With Upper Gastrointestinal Cancer
Cancer is a well known risk factor for venous thromboembolism (VTE) such as deep venous thrombosis (DVT) and pulmonary embolism (PE).
- Conditions
- Thrombosis, Deep Venous Thrombosis, Pulmonary Embolism, Venous Thromboembolism
- Trial name
- GIVTE (NCT00660205)
- Where
- Denmark
- Volunteers
- 285 people
- Sponsor
- University of Aarhus