Clinical trials: Cardiac Arrest (CA)
Cardiac Arrest (CA)
Physiology-directed Epinephrine Dosing in Pediatric Cardiac Arrest
This is a prospective, observational, multi-center cohort study of pediatric cardiac arrests. The purpose of this study is to evaluate the physiologic response to epinephrine as an outcome discriminator in pediatric in-hospital…
- Trial name
- PEDICA (NCT07890610)
- Where
- 22 sites in United States
- Volunteers
- 1,620 people
- Sponsor
- Children's Hospital of Philadelphia
Cardiac Arrest (CA), Pediatric ALL
Dutch Registry of Pediatric Cardiac Arrest
The goal of this observational study is to understand the long-term outcomes of children in the Netherlands who experience cardiac arrest, either in or outside of the hospital.
- Trial name
- PROGNOSE (NCT06938009)
- Where
- 7 sites in Netherlands
- Volunteers
- 500 people
- Sponsor
- Matthijs de Hoog
Cardiac Arrest (CA)
Does Increasing the Compression Pause From 3 to 5 Seconds in Mechanical Compression Devices Increase Ventilation Success Rate and Return of Spontaneous Circulation?
To give chest compressions during cardiopulmonary resuscitation (CPR), mechanical chest compression devices can be used. During synchronous 30:2 CPR, the standard setting on these devices leave an automated 3-second chest…
- Trial name
- LUCASVP (NCT06824961)
- Testing
- 5-second ventilation pause duration during mechanical CPR, 3-second ventilation pause duration during mechanical CPR
- Where
- 2 sites in Netherlands
- Volunteers
- 692 people
- Sponsor
- Amsterdam UMC, location VUmc
Chest Pain, Stroke Acute
Evaluation and Optimization of Telephone Triage Using Artificial Intelligence (AI) Models for the Detection of Demands for Time-dependent Pathology at the Emergency and Urgent Care Coordination Center (CCUE).
Improving Telephone Triage in Emergency Calls with AI The Coordinating Centre for Urgencies and Emergencies in Andalusia (CCUE) handles thousands of calls every day.
- Conditions
- Chest Pain, Stroke Acute, Respiratory Failure, Cardiac Arrest (CA)
- Trial name
- TrIAje Project (NCT07247669)
- Where
- Spain
- Volunteers
- 5,000,000 people
- Sponsor
- Centro de Emergencias Sanitarias 061 Andalucía
Medical Education, Simulation-based Methodology
MIxed ReAlity Versus Manikin Simulation in Basic Life Support Training for Medical Students: a Noninferiority Randomized Controlled Trial (MIRA).
Purpose: To compare the effectiveness of mixed reality and traditional manikin-based simulation in basic life support (BLS) training, making the hypothesis that mixed reality was non-inferior to manikin-based simulation.
- Conditions
- Medical Education, Simulation-based Methodology, Virtual Reality, Cardiac Arrest (CA)
- Trial name
- MIRA (NCT06832072)
- Testing
- MR-BLS
- Where
- France
- Volunteers
- 225 people
- Sponsor
- Sorbonne University
CPR, Cardiac Arrest (CA)
Effect of an Educational Intervention on CPR Knowledge and Skills in Schoolchildren
This study aims to evaluate the effectiveness of a CPR intervention for children aged 7 and 8. Given the high prevalence of out-of-hospital cardiac arrests (OHCA) and the proven benefits of early CPR training, the study seeks to…
- Trial name
- NCT06929715
- Testing
- Intervention for Teaching the First Link in the Chain of Survival to 7- and 8-Year-Old Children
- Where
- Colombia
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Extracorporeal Membrane Oxygenation Complication, ARDS (Acute Respiratory Distress Syndrome)
RECOMMEND Platform Trial
The goal of this platform trial is to determine the efficacy, safety and cost-effectiveness of various interventions in patients with acute cardiorespiratory failure requiring extracorporeal membrane oxygenation (ECMO) The main…
- Conditions
- Extracorporeal Membrane Oxygenation Complication, ARDS (Acute Respiratory Distress Syndrome), Intensive Care Medicine, Cardiac Arrest (CA)
- Trial name
- RECOMMEND (NCT06526533)
- Testing
- Liberal RBC Transfusion, Restrictive RBC Transfusion
- Where
- 3 sites in Australia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Cardiac Arrest (CA), Cardiogenic Shock
Evaluation of Acid-base Disorders and Ventilation Settings in Cardiogenic Shock and Post-cardiac Arrest Patients: Comparison With VentilO Algorithm
This study aims to better understand how mechanical ventilation settings affect patients admitted to the coronary care unit after cardiac arrest or with cardiogenic shock.
- Conditions
- Cardiac Arrest (CA), Cardiogenic Shock, Mechanical Ventilation, Acid Base Disorder
- Trial name
- VentilO CU (NCT07484828)
- Testing
- Initiation of mechanical ventilation
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Laval University
Cardiac Arrest (CA)
Effect of AED-optimized Telephone-assisted CPR Instructions on No-flow Time and Chest Compression Fraction
Out-of-hospital cardiac arrest (OHCA) remains a leading cause of mortality worldwide, with survival highly dependent on the immediate initiation of bystander cardiopulmonary resuscitation (CPR).
- Trial name
- NCT07520877
- Testing
- T-CPR, AED-optimized T-CPR
- Where
- Hungary
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Cardiac Arrest (CA)
Optimal Ventilation for Cardiac Arrest
Pediatric cardiac arrest is a life-threatening problem affecting >15,000 hospitalized children each year. Less than half of these children survive to hospital discharge, and neurologic morbidity is common among survivors.
- Trial name
- OPTI-VENT (NCT07114510)
- Testing
- OPTI-VENT Bundle, Transition, None - control
- Where
- 20 sites in United States
- Volunteers
- 1,530 people
- Sponsor
- Children's Hospital of Philadelphia
Cardiogenic Shock, Malignant Arrhythmias
The Caribbean Registry of Extracorporeal Membrane Oxygenation (ECMO) From the University Hospital in Martinique
The project's main goal is to collect baseline clinical and procedural data as well as to assess clinical outcomes for all patients undergoing VV, VA or VAV ECMO implantation in the French West Indies and Guiana.
- Conditions
- Cardiogenic Shock, Malignant Arrhythmias, Ischemic or Valvular Heart Failure, Drepanocytosis and Thoracic Syndrome
- Trial name
- NCT07351435
- Volunteers
- 1,200 people
- Sponsor
- University of Genova