Dental PlaqueNCT07555223
Intraoral Scan and CBCT-Aided Diagnosis of Dental Plaque and Caries
An observational study of Dental Plaque and Dental Caries, run by University Ghent at 1 site in Belgium.
Trial summary
This prospective clinical study aims to evaluate the diagnostic accuracy of intraoral scans (IOS) for the detection of dental plaque and caries. The diagnostic performance of IOS will be compared with current clinical reference standards. Read more about this study
- Who is it for?
- Ages 18 to 70 yearsHealthy volunteers can take part
- Conditions the study is for
- Dental Plaque, Dental Caries
- What is being tested?
- intraoral scan
- How many people
- 50 participants
- Where
- 1 siteBelgium
- Study dates
- 3 Apr 2025to Jul 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 70 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Adult patients aged 18 to 70 years undergoing intraoral examination in a clinical setting, with at least 20 teeth, who are not pregnant and able to provide informed consent.
Who may be able to join
- Adults aged 18 to 70 years
- Not pregnant and not planning pregnant
- At least 20 teeth present
- Ability to provide informed consent
Who cannot join
- Conditions that prevent proper intraoral examination (e.g., severe gag reflex, limited mouth opening)
- patient unable to provide informed consent
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Belgium1 site, 1 recruiting
- Recruiting
Tandarts Praktijk VERVACK
Wondelgem, Botestraat, 104
About this study
Official title: Intra Oral Scan and CBCT Aided Diagnosis of Dental Plaque and Caries
This prospective clinical study aims to evaluate the diagnostic accuracy of intraoral scans (IOS) for the detection of dental plaque and caries. The diagnostic performance of IOS will be compared with current clinical reference standards. For plaque assessment, IOS-based evaluation will be compared with plaque detection using disclosing agents. For caries detection, IOS (including white-light imaging and caries detection features) will be compared with conventional visual inspection and bitewing radiography. Adult patients aged 18 to 70 years will be included.
- Conditions
- Dental Plaque, Dental Caries
- Being tested
- intraoral scan
- Medical subject headings
- Dental Plaque, Dental Caries
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
intraoral scanDiagnostic test
intraoral scanning used for assessment of dental plaque and caries.
| Study group | Role | What they receive |
|---|---|---|
| Study Participants | All participants undergo intraoral scanning, visual inspection, plaque disclosure, and bitewing radiography for the assessment of dental plaque and caries. Receives: Diagnostic Test: intraoral scan |
What is being measured
The primary outcome is the main question the study is designed to answer.
Diagnostic Accuracy of Intraoral Scan for Dental Plaque Detection
Diagnostic accuracy of intraoral scan compared with plaque assessment using disclosing agents.
Measured: At baseline and 2 weeks
Secondary outcomes (1)
Agreement Between Intraoral Scan and Reference Standard for Dental Caries Detection
Agreement between intraoral scan assessments and reference standard (visual inspection and bitewing radiography) using kappa statistics.
Measured: At baseline and 2 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Apr 2026
- Study start3 Apr 2025
- Primary completionOct 2026 (estimated)
- Study completionJul 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Dental PlaqueStudies of the same condition, open and under way.
- More trials run by University GhentThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University Ghent
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07555223
- Sponsor's protocol ID
- ONZ-2024-0383
- Status last verified
- Apr 2026
- First submitted
- 21 Apr 2026
- Last updated
- 29 Apr 2026
- Results posted
- No
Study at a glance
From the registry record, last updated by the sponsor on 29 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Intra Oral Scan and CBCT Aided Diagnosis of Dental Plaque and Caries
- ClinicalTrials.gov ID
- NCT07555223
- Acronym / sponsor ID
- ONZ-2024-0383
- Conditions
- Dental Plaque, Dental Caries
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- University GhentUniversity, hospital or other
- Study start
- 3 Apr 2025 (actual)
- Primary completion
- Oct 2026 (estimated)
- Study completion
- Jul 2027 (estimated)
- First posted
- 29 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This prospective clinical study aims to evaluate the diagnostic accuracy of intraoral scans (IOS) for the detection of dental plaque and caries. The diagnostic performance of IOS will be compared with current clinical reference standards. For plaque assessment, IOS-based evaluation will be compared with plaque detection using disclosing agents. For caries detection, IOS (including white-light imaging and caries detection features) will be compared with conventional visual inspection and bitewing radiography. Adult patients aged 18 to 70 years will be included.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Study Participants | – | Diagnostic Test: intraoral scanAll participants undergo intraoral scanning, visual inspection, plaque disclosure, and bitewing radiography for the assessment of dental plaque and caries. |
Who may qualify
- Ages
- 18 to 70 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Adult patients aged 18 to 70 years undergoing intraoral examination in a clinical setting, with at least 20 teeth, who are not pregnant and able to provide informed consent.
Key inclusion criteria (4 listed)
- Adults aged 18 to 70 years
- Not pregnant and not planning pregnant
- At least 20 teeth present
- Ability to provide informed consent
Key exclusion criteria (2 listed)
- Conditions that prevent proper intraoral examination (e.g., severe gag reflex, limited mouth opening)
- patient unable to provide informed consent
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| intraoral scanintraoral scanning used for assessment of dental plaque and caries. | Diagnostic test | Study Participants |
Primary outcome
Diagnostic Accuracy of Intraoral Scan for Dental Plaque Detection
Time frame: At baseline and 2 weeks
Diagnostic accuracy of intraoral scan compared with plaque assessment using disclosing agents.
1 secondary outcome
Agreement Between Intraoral Scan and Reference Standard for Dental Caries Detection
Time frame: At baseline and 2 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Apr 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Dental Plaque and Dental Caries, run by University Ghent at 1 site in Belgium.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 29 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Belgium. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact sachiko maemoto (+32 93 32 40 57, Sachiko.Maemoto@ugent.be), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Diagnostic Accuracy of Intraoral Scan for Dental Plaque Detection (time frame: At baseline and 2 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Apr 2026.