Clinical trials: Dental Plaque
Dental Plaque
Effect of the SIMS Programme on Preschool Children's Oral Hygiene Level
This is a cluster randomised control trial targeting 5-6-year-old children and their parents in Kampar district, Perak, Malaysia for a period of 6 months.
- Trial name
- SIMSP (NCT04339647)
- Testing
- The SIMS programme
- Where
- Malaysia
- Volunteers
- 653 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Tooth Demineralization, White Spot Lesion
Comparison of a 3-step Bonding System (Transbond™ XT) and a 2-step System (GC Ortho Connect™) on Demineralization Around Maxillary Orthodontic Brackets
White spot lesions (WSLs) are one of the most common adverse effects of fixed orthodontic treatments, affecting up to 97% of patients treated with labial appliances.
- Conditions
- Tooth Demineralization, White Spot Lesion, Demineralization, Orthodontic Appliance Complication
- Trial name
- ORTHOCOLLAGE (NCT07355322)
- Testing
- Transbond™ XT bonding procedure, GC Ortho Connect™ bonding procedure
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Montpellier
Oral Health, Knowledge
Effectiveness MyBRUSH Module in Improving Knowledge, Attitude, and Behaviour on Toothpaste Use and Toothbrushing Among 12-Year-Old Children
The goal of this intervention study is to study the effectiveness of the oral health education module (MyBRUSH) in improving the knowledge, attitude, and behaviour on toothpaste use and toothbrushing among 12-year-old children.
- Conditions
- Oral Health, Knowledge, Attitude, Behavior
- Trial name
- MyBRUSH module (NCT07125560)
- Testing
- MyBRUSH module, BEGIN program
- Where
- 8 sites in Malaysia
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Gingivitis, Plaque, Dental
Gingivitis Reduction After Use of 0.45% Stannous Fluoride Toothpaste
The 6-month clinical study was designed to investigate clinical efficacy on plaque and gingivitis for the stannous fluoride containing toothpaste (SNAP) compared to Colgate Cavity Protection Toothpaste after 3 and 6 months of…
- Trial name
- NCT06300866
- Testing
- Test, Control
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Plaque, Gingivitis
A Clinical Study to Evaluate the Effectiveness of an Experimental Toothpaste in Improving Gum Health and Reducing Plaque Accumulation
The aim of this 24-week clinical study is to evaluate the ability of an experimental dentifrice containing 0.454 percent (%) weight by weight (w/w) Stannous fluoride (SnF2); to improve gingival health, plaque reduction and…
- Trial name
- NCT07255040
- Testing
- Test Dentifrice, Parodontax Complete Protection, Colgate Cavity Protection
- Where
- United States
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- HALEON
Dental Plaque, Side Effects
Clinical Effects of Two New Chlorhexidine Digluconate Formulations: 0.12% and 0.03%.
In the current study we tested the hypothesis that new 0.05% Cetylpyridinium chloride (CPC) mouthrinse formulations containing 0.12% or 0.03% chlorhexidine digluconate (CHX): 1) yield similar or better clinical results regarding…
- Trial name
- NCT02194023
- Testing
- 0.12%NF, 0.03%NF, PAT
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Menopause
Menopause and Oral Microbiome
The study examines the saliva and dental plaque microbiome of women aged 35-65 in two groups: postmenopausal (case) and premenopausal (control). For this purpose, Illumina Platform to sequence 16S rRNA gene regions will be used.
- Trial name
- NCT05335733
- Testing
- Intraoral examination, saliva, dental plaque and serum collection.
- Where
- Turkey (Türkiye)
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Ege University
Dental Plaque, Gingivitis
Essential Oil+ELA, Plaque and Gingivitis
A commercially available mouth rinse with ethyl lauroyl arginate and essential oils claims to have enhanced antimicrobial properties as compared to the traditional essential oil products.
- Trial name
- NCT02884817
- Testing
- Experimental: essential oils and ELA, Water
- Where
- Norway
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Dental Plaque
Development of Clinical Method to Triclosan Retention in Plaque Following Brushing
The objective is to develop a method to determine active ingredient uptake in oral care products.
- Trial name
- NCT00762853
- Testing
- Fluoride, Fluoride and triclosan
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Healthy
Comparison of Modified Circular and Natural Tooth Brushing Methods in Effectiveness of Dental Plaque Removal
1. Plaque level in subjects using the Modified Circular method is different from that in subjects using natural tooth brushing method. 2.
- Trial name
- NCT03547531
- Testing
- Natural Tooth Brushing Method, Modified Circular Tooth Brushing Method
- Where
- Indonesia
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Plaque, Dental
Plaque Removal Efficacy of Four Dentifrices Following a Single Brushing
The purpose of this study is to evaluate and compare plaque removal efficacy of four dentifrices following a single timed tooth brushing.
- Trial name
- NCT04794439
- Testing
- Dentifrices
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Dental Plaque, Calculus, Dental
Electric Toothbrush Efficacy in Preventing Dental Plaque Development
The present study will be the first to compared dental plaque quantitation between an oscillating-rotating electric toothbrush and a manual toothbrush with a new QLF technology.
- Trial name
- E-TOOTH (NCT06358482)
- Testing
- oscillating toothbrush, standard manual toothbrush
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Riccardo Polosa
Dental Plaque, Dental Caries
Probiotic Treatment of Orthodontic Patients
The purpose of this study is to examine the effect of treatment with a lozenge containing the probiotic strain S. salivarius M18 on the formation, composition and virulence of dental plaque and in healthy orthodontic patients…
- Trial name
- NCT06751979
- Testing
- Probiotic treatment
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Oral Hygiene, Oral Health, Plaque Score
Personalized Oral Hygiene Instruction Form
The objective of this study is to test a personalized oral hygiene instruction form (POHIF) elaborated after oral examination by a dentist and implemented by caregivers in nursing homes or similar medicalized homes.
- Conditions
- Oral Hygiene, Oral Health, Plaque Score, Dental Plaque Index, Denture Hygiene
- Trial name
- POHIF (NCT07063927)
- Testing
- personalized oral instruction form
- Where
- 2 sites in Switzerland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Dental Plaque
Plaque Removal Efficacy of a U-Shaped Sonic Power Toothbrush in Children
The objective of this single-use, examiner blinded, randomized, two-period, cross-over, IRB-approved clinical study is to evaluate the safety and plaque removal efficacy of AutoBrush®, a new children's 360° sonic toothbrush…
- Trial name
- NCT06300073
- Testing
- Experimental: U-shaped Power Toothbrush
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Lander Enterprises, LLC
pH, Saliva
Carbonated Beverage Consumption in pH and Bacterial Proliferation
The objective of this research is to evaluate the oral modifications caused by different types of coke drinks (regular coke and diet coke).
- Conditions
- pH, Saliva, Dental Plaque
- Trial name
- pHSB (NCT05437874)
- Testing
- Natural Water
- Where
- Mexico
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Dental Caries
Effect of Probiotic Drink on Number of Salivary Mutans Streptococci in School Going Children
This study was conducted to assess the effects of commercially available probiotic drink on the number of salivary mutans streptococci in school going children, aged 12-14 years in Bangalore city in India
- Trial name
- NCT01943123
- Testing
- probiotic drink
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Oxford Dental College, Hospital and Research Center, Bangalore, India
Periodontitis, Dental Plaque
Powered vs. Manual Toothbrushing in Stage 3-4 Periodontitis
This study compares the effectiveness of powered and manual toothbrushes in reducing gum bleeding and dental plaque in people with stage 3 or 4 periodontitis.
- Conditions
- Periodontitis, Dental Plaque, Gingival Bleeding
- Trial name
- NCT06980714
- Testing
- Powered, Manual
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of L'Aquila
Gingivitis, Plaque, Dental
Cetylpyridium Chloride (CPC) Based Chewing Gum and Gingivitis
This placebo-controlled, double-blinded, randomized crossover study evaluates the plaque and gingivitis reducing capacity of Cetylpyridium Chloride (CPC) chewing gum, with mechanical oral hygiene.
- Conditions
- Gingivitis, Plaque, Dental, Periodontal Diseases
- Trial name
- NCT03219840
- Testing
- Cetylpyridinium Chloride (CPC) 0.09% + Xylitol chewing gum, Xylitol only chewing gum
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Gingiva; Infection, Plaque, Dental
Role of Herbal Dentifrices in the Management of Plaque Induced Gingivitis
The clinical cross over study involves the use of two herbal based dentifirices moringa and miswak and its efficacy in reducing plaque induced gingivitis.
- Trial name
- NCT04830176
- Testing
- dentifrice
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ajman University